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EDA (ETHYLENE DIAMINE)

CAS NUMBER: 107-15-3

EC NUMBER: 203-468-6

MOLECULAR FORMULA: NH2CH2CH2NH2

MOLECULAR WEIGHT: 60.10

IUPAC NAME: ethane-1,2-diamine

EDA (Ethylene Diamine) is the organic compound with the formula C2H4(NH2)2. 
This colorless liquid with an ammonia-like odor is a basic amine. 

EDA (Ethylene Diamine) is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.
EDA (Ethylene Diamine) is the first member of the so-called polyethylene amines.

EDA (Ethylene Diamine) appears as a clear colorless liquid with an ammonia-like odor. 
EDA (Ethylene Diamine)'s Flash point of 91°F and a melting point of 47°F. 

EDA (Ethylene Diamine)'s vapors are heavier than air.
EDA (Ethylene Diamine)'s density 7.5 lb / gal.
EDA (Ethylene Diamine) is used to make other chemicals and as a fungicide.

EDA (Ethylene Diamine) is an alkane-alpha,omega-diamine in which the alkane is ethane. 
EDA (Ethylene Diamine) has a role as a GABA agonist. 

EDA (Ethylene Diamine) derives from a hydride of an ethane.
EDA (Ethylene Diamine) is an organic compound that is used as a building block for the production of many other chemical products. 

EDA (Ethylene Diamine) is also used as an excipient in many pharmacological preparations such as creams. 
Notably, EDA (Ethylene Diamine) is a contact sensitizer capable of producing local and generalized reactions. 
Sensitivity to EDA (Ethylene Diamine)e may be identified with a clinical patch test.

Applications:
EDA (Ethylene Diamine) is used in large quantities for production of many industrial chemicals. 
EDA (Ethylene Diamine) forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones. 
Because of EDA (Ethylene Diamine)'s bifunctional nature, having two amines, it readily forms heterocycles such as imidazolidines.

Precursor to chelation agents, drugs, and agrochemicals:
A most prominent derivative of EDA (Ethylene Diamine) is the chelating agent EDTA, which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde. 
Hydroxyethylethylenediamine is another commercially significant chelating agent.
Numerous bio-active compounds and drugs contain the N-CH2-CH2-N linkage, including some antihistamines.
Salts of ethylenebisdithiocarbamate are commercially significant fungicides under the brand names Maneb, Mancozeb, Zineb, and Metiram. 
Some imidazoline-containing fungicides are derived from ethylenediamine.

Pharmaceutical ingredient:
EDA (Ethylene Diamine) is an ingredient in the common bronchodilator drug aminophylline, where it serves to solubilize the active ingredient theophylline. 
EDA (Ethylene Diamine) has also been used in dermatologic preparations, but has been removed from some because of causing contact dermatitis.
When used as a pharmaceutical excipient, after oral administration its bioavailability is about 0.34, due to a substantial first-pass effect. 
Less than 20% is eliminated by renal excretion.

EDA (Ethylene Diamine)-derived antihistamines are the oldest of the five classes of first-generation antihistamines, beginning with piperoxan aka benodain, discovered in 1933 at the Pasteur Institute in France, and also including mepyramine, tripelennamine, and antazoline. 
The other classes are derivatives of ethanolamine, alkylamine, piperazine, and others (primarily tricyclic and tetracyclic compounds related to phenothiazines, tricyclic antidepressants, as well as the cyproheptadine-phenindamine family)

Role in polymers:
EDA (Ethylene Diamine), because it contains two amine groups, is a widely used precursor to various polymers. 
Condensates derived from formaldehyde are plasticizers. 
EDA (Ethylene Diamine) is widely used in the production of polyurethane fibers. 
The PAMAM class of dendrimers are derived from EDA (Ethylene Diamine).

Other applications:
-as a solvent, EDA (Ethylene Diamine) is miscible with polar solvents and is used to solubilize proteins such as albumins and casein. It is also used in certain electroplating baths.
-as a corrosion inhibitor in paints and coolants.
-ethylenediamine dihydroiodide (EDDI) is added to animal feeds as a source of iodide.
-chemicals for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxies, and dyes.
-as a compound to sensitize nitromethane into an explosive. 
This mixture was used at Picatinny Arsenal during WWII, giving the nitromethane and ethylenediamine mixture the nickname PLX, or Picatinny Liquid Explosive.

EDA (Ethylene Diamine) is a colorless, alkaline liquid with an ammonia-like odor. 
EDA (Ethylene Diamine) is a strong base that’s soluble in water, alcohol, ether, and insoluble in benzene. 

EDA (Ethylene Diamine) readily absorbs carbon dioxide from the air.
EDA (Ethylene Diamine) is used commonly in fungicides, chelating agents like EDTA, resins, textiles, lubricants, and as a solvent and emulsifying agent.

EDA (Ethylene Diamine) is used in adhesives and sealants, coating products, pH regulators and water treatment products, fillers, putties, plasters, modelling clay and water treatment chemicals.
EDA (Ethylene Diamine) is used in municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, health services and scientific research and development.

EDA (Ethylene Diamine) is used in fuels.
EDA (Ethylene Diamine) has an industrial use resulting in manufacture of another substance (use of intermediates).

EDA (Ethylene Diamine) is used in pH regulators and water treatment products, adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids and polymers.
EDA (Ethylene Diamine) is used for the manufacture of chemicals.


PHYSICAL PROPERTIES: 

-Molecular Weight: 60.10    

-XLogP3: -2    

-Exact Mass: 60.068748264    

-Monoisotopic Mass: 60.068748264    

-Topological Polar Surface Area: 52 Ų

-Physical Description: Colorless, viscous liquid with an ammonia-like odor

-Color: Water-white

-Form: Liquid

-Odor: Ammonia-like

-Boiling Point: 117.0 °C

-Melting Point: 11.1 °C

-Flash Point: 110 °F

-Solubility: 16.64 M

-Density: 0.898

-Vapor Density: 2.07

-Vapor Pressure: 12.00 mmHg

-Autoignition Temperature: 385 °CViscosity: 0.0154 cP

-Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic


EDA (Ethylene Diamine) is the organic compound with the formula C2H4(NH2)2. 
EDA (Ethylene Diamine) has an ammonia-like odor
EDA (Ethylene Diamine) is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.

EDA (Ethylene Diamine) is the first member of the so-called polyethylene amines.
EDA (Ethylene Diamine) appears as a clear colorless liquid with an ammonia-like odor. 

EDA (Ethylene Diamine)'s melting point is 47°F. 
EDA (Ethylene Diamine)'s vapors are heavier than air.
EDA (Ethylene Diamine) is used to make other chemicals and as a fungicide.


CHEICAL PROPERTIES: 

-Hydrogen Bond Donor Count: 2    

-Hydrogen Bond Acceptor Count: 2    

-Rotatable Bond Count: 1        

-Heavy Atom Count: 4    

-Formal Charge: 0    

-Complexity: 6    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 1    

-Compound Is Canonicalized: Yes


EDA (Ethylene Diamine) is an alkane-alpha,omega-diamine in which the alkane is ethane. 
EDA (Ethylene Diamine) derives from a hydride of an ethane.
EDA (Ethylene Diamine) is an organic compound that is used as a building block for the production of many other chemical products. 

EDA (Ethylene Diamine) is also used as an excipient in many pharmacological preparations such as creams. 
EDA (Ethylene Diamine) is used in large quantities for production of many industrial chemicals. 

EDA (Ethylene Diamine) is an ingredient in the common bronchodilator drug aminophylline, where it serves to solubilize the active ingredient theophylline. 
EDA (Ethylene Diamine) has also been used in dermatologic preparations, but has been removed from some because of causing contact dermatitis.

EDA (Ethylene Diamine) is miscible with polar solvents and is used to solubilize proteins such as albumins and casein. It is also used in certain electroplating baths.
EDA (Ethylene Diamine) is a colorless, alkaline liquid with an ammonia-like odor. 

EDA (Ethylene Diamine) is a strong base that’s soluble in water, alcohol, ether, and insoluble in benzene. 
EDA (Ethylene Diamine) readily absorbs carbon dioxide from the air.

EDA (Ethylene Diamine) is used commonly in fungicides, chelating agents like EDTA, resins, textiles, lubricants, and as a solvent and emulsifying agent.
EDA (Ethylene Diamine) is used in adhesives and sealants, coating products, pH regulators and water treatment products, fillers, putties, plasters, modelling clay and water treatment chemicals.

EDA (Ethylene Diamine) is used in municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, health services and scientific research and development.
EDA (Ethylene Diamine) is used in fuels.

EDA (Ethylene Diamine) has an industrial use resulting in manufacture of another substance (use of intermediates).
EDA (Ethylene Diamine) is used in pH regulators and water treatment products, adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids and polymers.


SYNONYMS: 

ethylenediamine
Ethane-1,2-diamine
107-15-3
1,2-Ethanediamine
1,2-Diaminoethane
Ethylene diamine
Ethylendiamine
edamine
Dimethylenediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Ethyleendiamine
Ethylene-diamine
beta-Aminoethylamine
1,2-Diaminoaethan
Algicode 106L
Amerstat 274
1,2-Diamino-ethaan
1,2-Diamino-ethano
ETHYLENEDIAMINE ANHYDROUS
2-Aminoethylammonium chloride
1, 2-Diaminoethane
1,2-diaminoethane phase II
1,2-diaminoethane
Aethaldiamin
1,2-diaminoethane
Ethylenediamine
Polyamines
Ethyleendiamine
Aethylenediamin
Ethylene-diamine
1,2-Diaminoaethan
1,2-Diamino-ethaan
1,2-Diamino-ethano
ethylenediarnine
1,2-Ethanediamine, homopolymer
2-aminoethylamine
ethylene di amine
1,4-diazabutane
1,2-diaminoethan
Ethylenediamine, piperazine polymer
ethylene - diamine
EDN
1,2-ethylendiamine
Edamine
1,2-diamino-ethane
ethane 1,2-diamine
N,N'-ethylenediamine
Ethylenediamine, 8CI
1,2-ethylene diamine
1,2-ethylene-diamine
Ethylenediamine
.beta.-Aminoethylamine
ethane-1, 2-diamine
Ethylenediamine solution
N,N'-ethylene diamine
1,2-Ethanediamine,homopolymer
624-59-9 (di-hydrobromide)
333-18-6 (di-hydrochloride)
5700-49-2 (di-hydriodide)
Ethylenediamine, for synthesis, 99.0%
Ethylenediamine

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