PRODUCTS

EDTA 2Na

Edta 2Na can be used as a cosmetic additive.
Edta 2Na can be used as food additive.
Edta 2Na can be used in agriculture fertilizer etc.

CAS Number: 139-33-3 (anhydrous form) — and related hydrate forms such as 6381-92-6 for dihydrate
EC Number: 205-358-3
MDL Number: MFCD00070672
Molecular Formula: C₁₀H₁₄N₂Na₂O₈
Molecular Weight: ~336.21 g/mol

SYNONYMS:
Disodium EDTA, Isodium dihydrogen ethylenediaminetetraacetate, Edetic acid disodium salt, EDTA disodium salt, (Ethylenedinitrilo)tetraacetic acid disodium salt, Disodium Edetate, Chelaplex, Chelaplex III, Chelaton III, Chelest 200, Chelest 2B-SD, Chelest 2BS, Chelest B, Clewat N, Clewat N 2, Complexon III, Disodium (Ethylenedinitrilo)tetraacetate, Disodium EDTA, Disodium Diacid Ethylenediaminetetraacetate, Disodium Dihydrogen Ethylenediaminetetraacetate, 1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID DISODIUM SALT, 1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID DISODIUM SALT 2H2O, 4C EDTA, COMPLEXONE III, COMPLEXONE III(R), DISODIUM DIHYDROGEN ETHYLENEDIAMINE TETRAACETATE, DISODIUM DIHYDROGEN ETHYLENEDIAMINETETRAACETATE DIHYDRATE, DISODIUM DIHYDROGEN ETHYLENEDIAMINETETRA-ACETIC DIHYDRATE, DISODIUM EDETATE, DISODIUM EDETATE DIHYDRATE, DISODIUM EDTA, DISODIUM ETHYLENEDIAMINETETRAACETATE, DISODIUM ETHYLENEDIAMINETETRAACETATE DIHYDRATE, Disodium ethylenediaminetetraacetic acid, DISODIUM (ETHYLENEDINITRILO)TETRAACETATE, DIHYDRATE, EDATHAMIL DISODIUM SALT DIHYDRATE, EDETATE DISODIUM, EDETATE DISODIUM, DIHYDRATE, EDETATE DISODIUM DIHYDROGEN, DIHYDRATE, EDETATE DISODIUM SALT DIHYDRATE, (Ethylenedinitrilo)tetraacetic acid disodium salt, EDTA disodium salt, EDTA-Na2, (Ethylenedinitrilo)tetraacetic Acid Disodium Salt, EDTA Disodium Salt, EDTA-Na2, Ethylenediamine-N,N,N',N'-tetraacetic Acid Disodium Salt, EDNRA, 1,2-Diaminoethane-N,N,N',N'-tetra-acetic Acid Sisodium Salt, ETHYLENEBIS(IMINODIACETIC ACID)DISODIUM SALT, ETHYLENEDIAMINETETRAACETIC ACID, 2NA, DIHYDRATE, ETHYLENE DIAMINETETRA ACETIC ACID DISODIUM, ETHYLENEDIAMINE TETRAACETIC ACID DISODIUM DIHYDRATE, ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT, ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT-2-HYDRATE, ETHYLENEDIAMINE-N,N,N',N'-TETRAACETIC ACID DISODIUM SALT, ETHYLENEDIAMINETETRAACETATE DISODIUM SALT, (ETHYLENENDINITRILO)TETRAACETIC ACID, DISODIUM SALT, DIHYDRATE, (ETHYLENEDINITRILO)TETRAACETIC DISODIUM, DIHYDRATE, Disodium EDTA, Disodium dihydrogen ethylenediaminetetraacetate, Disodium edetate, Disodium ethylenediamine tetraacetate, Edetate disodium, Ethylenediaminetetraacetic acid, disodium salt, (Ethylenedinitrilo) tetraacetic acid, sodium salt, Glycine, N,N-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt dihydrate, Chelaplex, Chelaplex III, Chelaton III, Chelest B, Disodium (Ethylenedinitrilo)tetraacetate, Disodium EDTA, Disodium Diacid Ethylenediaminetetraacetate, Disodium Dihydrogen Ethylenediaminetetraacetate, Disodium Edathamil, Disodium Edetate, Disodium Ethylenediamine-N,N,N',N'-tetraacetate, Disodium Ethylenediaminetetraacetate, Disodium Ethylenediaminetetraacetic Acid Salt, Disodium Sequestrene, Disodium Tetracemate, Disodium Versenate, Disodium Versene, EDTA Disodium Salt, Edathamil Disodium, Edetate Disodium, Endrate Disodium, Ethylenedinitrilotetraacetate Disodium, EDTA-2NA, DISODIUM EDTA, DISODIUM EDETATE, ETA, EDETATE DISODIUM, EDTA DISODIUM, EDTA DISODIUM SALT, TITRIPLEX III, DISODIUM ETHYLENEDIAMINETETRAACETATE, EDTA NA2, Ethylenediaminetetra-acetic acid disodium salt dihydrate, Edetate disodium dihydrate, Ethylenediaminetetraacetic acid, disodium salt, dihydrate, Kestranal 2S 2 H2O, Ethylenedinitrilotetra-acetic acid disodium salt dihydrate, Titriplex III, Kestranal 2S dihydrate, Edetic acid disodium salt dihydrate, Disodium dihydrogen ethylenediaminetetraacetate dihydrate, EDTA-2Na, Disodium EDTA, Disodium Edetate, EDTA Disodium Salt, Disodium Ethylenediaminetetraacetate, ETA, Titriplex III, EDTA Na₂, Disodium EDTA dihydrate (for hydrated forms), EDTA Disodium Salt, Disodium (Ethylene-dinitrilo)tetraacetate, Complexone III, Disodium EDTA, Isodium dihydrogen ethylenediaminetetraacetate, Edetic acid disodium salt, EDTA disodium salt, (Ethylenedinitrilo)tetraacetic acid disodium salt, Disodium Edetate

Ethylenediaminetetraacetic Acid Disodium, commonly known as Edta 2Na for short, is a widely used chelating agent in detergents, personal care products, and cosmetics.
Edta 2Na effectively binds to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes in an aqueous solution, thus preventing these metal ions from bonding to the surfactants, which are commonly ionic in cleaning formulas.

In this way, Edta 2Na contributes to softening the water and maintaining the effectiveness of the surfactant.
Edta 2Na also features outstanding sequestering ability and bacteria-inhibiting ability to improve the stability of the products in the air to increase their shelf life.

Edta 2Na (Ethylenediaminetetraacetic acid disodium salt) is a chelating agent with the chemical formula C10H14N2O8Na2.
Edta 2Na is a white, crystalline powder that is highly soluble in water.
Edta 2Na (Ethylenediaminetetraacetic acid disodium salt) is a widely used chelating agent that forms stable complexes with metal ions, making it useful in fields such as analytical chemistry, medicine, agriculture, and industry.

To create Edta 2Na, ethylenediamine and chloroacetic acid combine to form EDTA, which is subsequently neutralized with sodium hydroxide to yield the disodium salt.
The process involves first reacting ethylenediamine and chloroacetic acid in an alkaline medium, followed by adding sodium hydroxide to yield

Edta 2Na, which is then purified by crystallization.
Edta 2Na is a small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1982 and is indicated for eye disease and has 4 investigational indications.
Edta itself has multiple salt forms (disodium, tetrasodium, calcium disodium) but all share the primary function of chelating metal ions.

USES and APPLICATIONS of EDTA 2Na:
Edta 2Na is used Washing and cleaning products, coating products, polishes and waxes, biocides (eg disinfectants, pest control products), adhesives and sealants, fillers, putties, plasters, modeling clay, non-metal surface treatment products, metal surface treatment products.
Edta 2Na is widely used in air care products, photo-chemicals, textile processing products and dyes.

Edta 2Na is used in machine wash fluids/detergents, automotive care products, paints, coatings or adhesives, fragrances and air fresheners, coolants in refrigerators, and oil-based electric heaters.
Edta 2Na is used hydraulic fluids in automotive suspension, lubrica

Edta 2Na is used brake fluids in engine oil, upholstery, furniture, toys, construction materials, curtains, shoes, leather products, paper and cardboard products, and electronic equipment.
Edta 2Na is used for sanding fabrics, textiles, interior paint removal, metal, wood, plastic building and building materials, tyres, engineered wood products, treated textiles and fabrics, brake pads on trucks or cars, buildings (bridges, facades) or vehicles (ships).

Edta 2Na can be applicable to detergent, dyeing adjuvant, and processing agents for fibers.
Edta 2Na can be used as a cosmetic additive.
Edta 2Na can be used as food additive.

Edta 2Na can be used in agriculture fertilizer etc.
Edta 2Na is a versatile chelating agent, meaning it can effectively bind to metal ions, forming stable, water-soluble complexes.
This unique property makes Edta 2Na a valuable compound across a wide range of industries.

Analytical Chemistry: Complexometric Titrations: Edta 2Na is used as a titrant in complexometric titrations for the determination of metal ion concentrations.
Edta 2Na is used as a sequestrant in cleaning and laundry products, in water treatment, and in the food industry as a preservative and a color stabilizer.

Personal Care: Edta 2Na is used in shampoos, conditioners, and cleansers, it binds to metal ions in hard water, improving foaming and cleansing effectiveness.
Cosmetics & Skin Care: Edta 2Na stabilizes products like moisturizers and sunscreens by preventing oxidation and discoloration due to metal impurities, enhancing shelf life and texture.

Pharmaceuticals: In IV solutions and vaccines, Edta 2Na prevents metal ion contamination and stabilizes active ingredients.
Detoxification treatments can employ Edta 2Na to rid the body of heavy metals.
Food & Beverage: Edta 2Na acts as a preservative and stabilizer, preventing discoloration and degradation in processed foods and beverages.

Edta 2Na is commonly employed for metal ion separation, analysis, and removal.
EDTA 2Na is incorporated in personal care products to chelate and sequester metal ions, in an effort to increase shelf life and enhance the products foaming properties.

Edta 2Na is used in shampoo, dyes, lotion, gel, cosmetics.
Edta 2Na has a pH lower than 7.

Edta 2Na (ethylenediaminetetracetic acid disodium) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.
Industrial & Household uses of Edta 2Na: Water softening: Binds Ca²⁺ and Mg²⁺ preventing soap scum and scale buildup.

Cleaning & Detergents: Edta 2Na is added to laundry and dish detergents to enhance cleaning by sequestering hardness ions.
Fixer & Photographic Solutions: Edta 2Na helps stabilize solutions by binding metal contaminants.
Paper & Textile: Edta 2Na chelates metal ions that influence coloration or interfere with process chemistry.

pH Modifying & Corrosion Control: Edta 2Na is used where metal ions might accelerate degradation.
Cosmetics & Personal Care: Edta 2Na acts as a sequestering agent to improve stability, prevent discoloration, and enhance performance of soaps, shampoos, creams, lotions.

Food & Beverage: Edta 2Na is used in some food products as a sequestrant and to prevent oxidative spoilage by binding metal catalysts.
Personal Care Applications: Edta 2Na is used in Cosmetics to increase effectiveness and improve stability of bar and solid soaps, bath preparations; creams, oils, hair care products and many other personal care formulations.

-Industrial Applications of Edta 2Na:
Edta 2Na is used in cleaners, detergent, fertilizers, fixer solution for development of colour film, water cleaner and pH modifier.
Edta 2Na is also used in redox reaction for the polymerization of butyl benzene rubber.
Edta 2Na is used as part of activator for the control of polymerization speed.

-Laboratory & Medical uses of Edta 2Na:
*Biochemistry & Molecular Biology:
Edta 2Na is used to chelate metal ions, inhibiting metal-dependent enzymes and preserving samples.

*Diagnostic Blood Collection:
Edta 2Na is often used as anticoagulants in blood collection tubes (binds Ca²⁺ to prevent clotting).

*Medicine:
Certain EDTA salts (e.g., sodium calcium edetate) used in chelation therapy for heavy metal poisoning.
Note: Edta 2Na itself may be used medically with care.

-Industrial Cleaning:
Edta 2Na is added to detergents and cleaning agents to remove mineral deposits, limescale, and soap scum by chelating metal ions that reduce cleaning effectiveness.
Water treatment is the process of eliminating metal impurities from water to stop scaling and enhance the quality of water in industrial systems.

*Metalworking:
Edta 2Na prevents rust and metal deposits in coolants and lubricants, enhancing the performance of metalworking processes.

-Water Treatment uses of Edta 2Na:
*Sequestering Metal Ions:
Effectively binds to metal ions like calcium, magnesium, iron, and copper, preventing their precipitation and deposition on equipment surfaces.

*Corrosion Inhibition:
Edta 2Na helps control corrosion in industrial water systems by preventing the formation of corrosive deposits.

*Scale Prevention:
Edta 2Na prevents the formation of scale in boilers, cooling towers, and heat exchangers, improving equipment efficiency and longevity.

-Detergents and Cleaning Products use of Edta 2Na:
*Improved Cleaning Performance:
Edta 2Na enhances the cleaning effectiveness of detergents by sequestering metal ions that can interfere with surfactant action, leading to better cleaning results.

*Hard Water Softening:
Edta 2Na helps soften hard water by binding to calcium and magnesium ions, reducing their impact on cleaning performance.

*Used in various cleaning products:
Including laundry detergents, dishwashing detergents, and personal care products like shampoos and cosmetics.

-Food Industry uses of Edta 2Na:
*Food Preservative:
Edta 2Na is employed as a food additive (E386) to stabilize and preserve food products by chelating metal ions that can catalyze oxidation reactions.

*Beverage Stabilization:
Edta 2Na is used in the production of beverages to improve their stability and prevent the formation of haze or cloudiness.

*Flavor Enhancement:
Edta 2Na can enhance the flavor of certain foods by preventing metal-catalyzed reactions.

-Industrial Applications of Edta 2Na:
*Textile Dyeing:
Edta 2Na improves dye fixation and colorfastness in textile dyeing processes.

*Paper Manufacturing:
Edta 2Na is used in paper manufacturing processes to improve paper quality and strength.

*Metal Finishing:
Edta 2Na is employed in various metal finishing processes, such as electroplating and metal cleaning.

-Pharmaceutical Industry uses of Edta 2Na:
*Pharmaceutical Formulations:
Edta 2Na is used as a stabilizer and chelating agent in the formulation of various pharmaceuticals.

*Anticoagulant:
Edta 2Na is used as an anticoagulant in blood collection and processing.

*Drug Delivery:
Edta 2Na is used in drug delivery systems to improve the stability and bioavailability of certain medications.

FUNCTIONAL PROPERTIES & BENEFITS of EDTA 2Na:
*Chelating Agent:
Strong binding with divalent and polyvalent metal ions.

*Stabilizer & Sequestrant:
Edta 2Na prevents metal-catalyzed deterioration in formulations.

*Improves Product Performance:
Edta 2Na enhances detergent cleaning, prevents discoloration or precipitation.

*Versatile:
Edta 2Na is used across industries — detergents, cosmetics, food, lab, and industrial chemicals.

FEATURES & BENEFITS of EDTA 2Na:
Highly effective in chelating metal ions to maintain the activeness of the surfactants used in detergent, personal care, and cosmetic formulas.

Outstanding sequestering ability and bacteria-inhibiting ability to improve the stability of personal care products and cosmetics in the air, so to increase their shelf life.

PROPERTIES of EDTA 2Na:
Edta 2Na appears as a white crystal powder.
Edta 2Na can be soluble in water.
Edta 2Na cannot be nearly soluble in alcohol and acid in water.
About the Edta 2Na solubility in water.
At 22 ℃, 10.8g~11.1g of Edta 2Na can be dissolved in 100 ml water.

FUNCTIONS of EDTA 2Na:
*Preservative
*Scale Inhibitor
*Stabilizer
*Lubricant

INDUSTRY of EDTA 2Na:
*Cosmetic
*Plating
*Pharmaceutical
*Water Treatment
*Textiles
*Adhesives
*Detergent

PROPERTIES of EDTA 2Na:
Appearance:
Edta 2Na is a white crystalline solid or powder

Odor:
Edta 2Na is odorless or characteristic mild odor in some technical grades

Melting Point:
~245–250 °C (decomposes)

Boiling Point:
Edta 2Na is not well defined; decomposes before boiling

Density:
~1.01 g/mL (solid)

Solubility:
Edta 2Na is highly soluble in water; forms clear solutions

pH:
Around 8.0 ±0.2 in aqueous solution

Stability:
Stable under normal ambient conditions; hygroscopic (absorbs moisture)

Edta 2Na is the disodium salt of Ethylenediaminetetraacetic acid (EDTA), an aminopolycarboxylic acid chelating agent.
Edta 2Na binds strongly to metal cations (like Ca²⁺, Mg²⁺, Fe²⁺/Fe³⁺), forming stable, water-soluble complexes and thereby sequesters metal ions in solution.
Chelation inhibits metal-ion-catalyzed reactions and improves product stability.

PHYSICAL and CHEMICAL PROPERTIES of EDTA 2Na:
Formula: [CH2N(CH2COOH)CH2COONa]2·2H2O
Appearance: white crystals
Assay: 99% min.
Specific gravity: 0.8 - 1.1 kg/l at 20°C
pH: 4,5-5 in 10% aqueous solution
Appearance: white crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in: water, 1e+006 mg/L @ 25 °C (est)

Insoluble in: alcohol
Form: powder
Colour: white
Odour: product specific
Odour threshold:
not determined
pH value: 4 - 5 (DIN 19268)
Melting point: 248 °C (dec.)(lit.)
Boiling point: >100 °C
Density: 1.01 g/mL at 25 °C

vapor pressure: 0Pa at 25℃
storage temp.: 2-8°C
solubility: H2O: clear, colorless
form: solution
color: ≤5 (0.5 M)(APHA)
Water Solubility: Miscible with water.
BRN: 3822669
Stability: Hygroscopic
LogP: -4.3 at 25℃
Self ignition: not self-igniting

Test type: Spontaneous selfignition at room-temperature.
Temperature: > 400 °C Test type: Self-ignition at high
Pressure: 1.013,25 hPa temperatures.
No self ignition was observed up to (Method: Regulation
the specified temperature. 440/2008/EC, A.16)
Viscosity, dynamic:
Study scientifically not justified.
Viscosity, kinematic: not applicable, the product is a solid

Explosion hazard: Product is not explosive, however a dust explosion could result from an air / dust mixture.
Fire promoting properties: Based on its structural properties the product is not classified as oxidizing.
Other information:
Self heating ability: It is not a substance capable of spontaneous heating.
Minimum ignition energy: > 4 J (DIN EN 13821) (1.013,25 hPa, 20 °C)
Bulk density: approx. 950 kg/m3 (DIN ISO 697)
Surface tension: Based on chemical structure, surface activity is not to be expected.
Grain size distribution: particles < 100 µm approx. 29 %
particles < 10 µm approx. 1,2 %
particles < 4 µm approx. 0,2 %

Melting Point: >250°C (dec.)
Density: 1.01 g/mL at 25°C
InChI Key: ZGTMUACCHSMWAC-UHFFFAOYSA-L
Stability: Stable.
Molecular Formula: C₁₀H₁₄N₂Na₂O₈
Appearance: White to Off-White Solid
Melting Point: >250°C (dec.)
Molecular Weight: 336.21
Storage: 4°C, Hygroscopic

Solubility: Aqueous Base (Slightly), Water (Sparingly, Sonicated)
Stability: Hygroscopic
Name: Ethylenediaminetetraacetic acid disodium salt
Common Abbreviation: EDTA 2Na
CAS Number: 139-33-3 (anhydrous form) — and related hydrate forms such as 6381-92-6 for dihydrate
EC (EINECS) Number: 205-358-3
Molecular Formula: C₁₀H₁₄N₂Na₂O₈
Molecular Weight: ~336.21 g/mol
PubChem CID: 13020083 (Disodium EDTA)

Appearance: White crystalline solid or powder
Odor: Odorless or characteristic mild odor in some technical grades
Melting Point: ~245–250 °C (decomposes)
Boiling Point: Not well defined; decomposes before boiling
Density: ~1.01 g/mL (solid)
Solubility: Highly soluble in water; forms clear solutions
pH: Around 8.0 ±0.2 in aqueous solution
Stability: Stable under normal ambient conditions; hygroscopic (absorbs moisture)

FIRST AID MEASURES of EDTA 2Na:
-Description of first aid measures:
Remove contaminated clothing.
*If inhaled:
Keep patient calm, remove to fresh air, seek medical attention.
*On skin contact:
Wash thoroughly with soap and water.
*On contact with eyes:
Wash affected eyes for at least 15 minutes under running water with eyelids held open.
*On ingestion:
Immediately rinse mouth and then drink 200-300 ml of water, seek medical attention.
-Indication of any immediate medical attention and special treatment needed:
*Treatment:
Treat according to symptoms, with no known specific antidote.

ACCIDENTAL RELEASE MEASURES of EDTA 2Na:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective clothing.
-Environmental precautions:
Contain contaminated water/firefighting water.
Do not discharge into drains/surface waters/groundwater.
-Methods and material for containment and cleaning up:
*For small amounts:
Pick up with suitable appliance and dispose of.
*For large amounts:
Contain with dust binding material and dispose of.
Dispose of absorbed material in accordance with regulations.

FIRE FIGHTING MEASURES of EDTA 2Na:
-Extinguishing media:
*Suitable extinguishing media:
dry powder, foam
-Advice for fire-fighters:
*Further information:
Contaminated extinguishing water must be disposed of in accordance with official regulations.

EXPOSURE CONTROLS/PERSONAL PROTECTION of EDTA 2Na:
-Exposure controls:
--Personal protective equipment:
*Hand protection:
Chemical resistant protective gloves.
*Supplementary note:
Manufacturer's directions for use should be observed because of great diversity of types.
*Eye protection:
Safety glasses with side-shields (frame goggles)
-General safety and hygiene measures:
Wearing of closed work clothing is recommended.
No eating, drinking, smoking or tobacco use at the place of work.
Handle in accordance with good industrial hygiene and safety practice.

HANDLING and STORAGE of EDTA 2Na:
-Conditions for safe storage, including any incompatibilities:
*Suitable materials for containers:
Low density polyethylene (LDPE), glass, Paper/Fibreboard, High density polyethylene (HDPE)
-Further information on storage conditions:
Keep container tightly closed and dry; store in a cool place.

STABILITY and REACTIVITY of EDTA 2Na:
-Reactivity:
No hazardous reactions if stored and handled as prescribed/indicated.
*Corrosion to metals:
No corrosive effect on metal.
-Chemical stability:
The product is stable if stored and handled as prescribed/indicated.