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ETHOXYDIGLYCOL

DESCRIPTION:
Ethoxydiglycol is a solubilizer, solvent, humectant, moisturizer, and perfuming agent widely used in cosmetics and personal care products. 
Ethoxydiglycol boosts the efficacy of cosmetic formulations. 
Its chemical formula is C6H14O3.

CAS Number    111-90-0
EINECS/ELINCS No:    203-919-7
Chem/IUPAC Name:    2-(2-Ethoxyethoxy)ethanol; Carbitol; Diethylene glycol monoethyl ether; DEGEE
COSING REF No:    33802
INCI name: ETHOXYDIGLYCOL

SYNONYMS OF ETHOXYDIGLYCOL:
Diethylene Glycol Monoethyl Ether, 2-(2-Ethoxyethoxy)ethanol.


Ethoxydiglycol is a widely used as solubilizer, solvent carrier, fragrance enhancer, humectant, co-solvent and viscosity decreasing agent. 
Ethoxydiglycol is Superior solubilizer and efficacy booster for cosmetic formulations. 
Ethoxydiglycol Enhances skin penetration of cosmetic actives. 

Ethoxydiglycol Helps repair split ends of damaged hairs. Improves color fixation of self-tanning products with DHA. 
Due to its excellent solubilizing properties Ethoxydiglycol has application in almost every type of cosmetic product.


Ethoxydiglycol also known as diethylene glycol monethyl ether, is a cosmetic grade solvent that conforms to the current USP/NF monographs. 
Ethoxydiglycol is particularly appropriate for skin care preparations where Ethoxydiglycol acts as an excellent solvent and carrier. 

Its solubility in ethanol, propylene glycol, vegetable oils, water, and butylene glycol makes it a valuable solvent or co-solvent which can be used in hydrophilic or lipophilic phases.

Ethoxydiglycol (Diethylene glycol monoethyl ether) is a synthetic derivative (ethoxylated) of grain alcohol (drinking alcohol; ethanol) widely used in skin and hair care applications as an excellent solvent, carrier, viscosity modifier, humectant, penetration enhancer, fragrance, etc. 

Thanks to a potent solubilizing property, Ethoxydiglycol solves insoluble or sparingly soluble active ingredients like Sulfur or Copper Usnate while decreasing the viscosity of the formula. 
In many applications, it improves penetration levels and boosts the efficiency of active ingredients.


Diethylene glycol monoethyl ether possesses outstanding safety and versatility in both water and oil-based preparations, additionally moisturizing and conditioning the skin. 
In addition, it improves skin feel, lubricating and spreading properties of the product.

In hair care applications, Ethoxydiglycol delivers long-lasting and uniform color fixation, preventing and repairing split ends. 
Ethoxydiglycol is utilized in all types of skin and hair care products, including anti-acne, self-tanning, and hair conditioning preparations, as well as cleansers, antiperspirants, and soaps.


Ethoxydiglycol also known as diethylene glycol monethyl ether is a solvent, penetration enhancer, solubilizer, and humectant.

Ethoxydiglycol is odorless liquid used mainly as a superior solubilizer and efficacy booster due to its ability to make ingredients penetrate the skin better.

Ethoxydiglycol functions as a humectant and attracts moisture from the air and draws it into your skin, it improves moisture retention in the skin, and may help other topical ingredients to perform well. 

Ethoxydiglycol prevents the skin from drying and also delays the signs of aging. 
Ethoxydiglycol is used at a concentration of 1-10%. It boosts the efficacy of certain active ingredients.

Ethoxydiglycol gives a longer-lasting and more uniform color to the hair, and also prevents split ends. 

Solvents like ethoxydiglycol are used to make thinner formulations and decrease the viscosity of a formulation to make the formulation readily spreadable on the skin or hair,
Ethoxydiglycol is non-irritating, non-penetrating, and non-comedogenic when applied to the skin.
 The Cosmetics Ingredient Review (CIR) concludes it to be safe for use in cosmetics and personal care products.


Restriction in Europe: III/297
The restrictions and maximum permitted concentrations are dependent on the use of the ingredient in:
a) Oxidative hair dyes: 7%.
b) Non-oxidative hair dyes: 5%.
c) Rinse-off products other than hair dyes: 10%.
d) Other cosmetic products that are not in spray form: 2.6%.
e) The following spray products: fine perfumes, personal care products, antiperspirants and deodorants: 2.6%.


FUNCTIONS (INCI) OF ETHOXYDIGLYCOL:
Humectant: Maintains the water content of a cosmetic in its packaging and on the skin
Solvent: Dissolves other substances
Fragrance agent: Used for perfume and aromatic raw materials


USES OF ETHOXYDIGLYCOL
Ethoxydiglycol is primarily used as a solvent in cosmetics to help dissolve or suspend other formulation ingredients. 
Ethoxydiglycol is soluble in various other solvents like ethanol, propylene glycol, and vegetable oil, due to which it is found in almost every other cosmetic product like antiperspirants, soaps, nail polish removers, fragrances, hair conditioners, etc.


Skin care: 
Ethoxydiglycol functions as a humectant and attracts moisture from the air and draws it into your skin, it improves moisture retention in the skin, and may help other topical ingredients to perform well. 

Ethoxydiglycol prevents the skin from drying and also delays the signs of aging. 
Ethoxydiglycol is used at a concentration of 1-10%. 
Ethoxydiglycol boosts the efficacy of certain active ingredients like vitamin C, self-tanning active DHA, or benzoyl peroxide and is thus used in vitamin C serums

Hair care: 
Ethoxydiglycol gives a longer-lasting and more uniform color to the hair, and also prevents split ends. 
Solvents like ethoxydiglycol are used to make thinner formulations and decrease the viscosity of a formulation to make the formulation readily spreadable on the skin or hair

Origin
The ethoxylation of ethanol produces Ethoxydiglycol. 
Ethoxylation is a chemical reaction in which ethylene oxide is added to a substrate. 
In this case, the substrate is ethanol, a type of alcohol.

What does ETHOXYDIGLYCOL do in a formulation?
•    Humectant
•    Solvent
•    Perfuming


CHEMICAL AND PHYSICAL PROPERTIES OF ETHOXYDIGLYCOL:

Boiling Point    196°C
Melting Point    -77.7°C
Solubility    Soluble in ethyl ether, miscible with water, ethanol, acetone, benzene
Viscosity    3.85 mPa.s
Functions
Humectant
Perfuming
Solvent
CAS Number(s)
111-90-0
EINECS number(s)
203-919-7
FDA UNII
A1A1I8X02B


SAFETY INFORMATION ABOUT ETHOXYDIGLYCOL:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician. 
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:
 
If inhaled:
If breathed in, move person into fresh air. 
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately. 
Wash off with soap and plenty of water.
Consult a physician.
 
In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
 
If swallowed:
Do NOT induce vomiting. 
Never give anything by mouth to an unconscious person. 
Rinse mouth with water. 
Consult a physician.
 
Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
 
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. 
 
Avoid breathing vapours, mist or gas. 
Evacuate personnel to safe areas.
 
Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
 
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste. 
Keep in suitable, closed containers for disposal.
 
Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.
 
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place. 
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
 
Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
 
Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles. 
Faceshield (8-inch minimum). 
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
 
Skin protection:
Handle with gloves. 
Gloves must be inspected prior to use. 
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product. 
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. 
Wash and dry hands.
 
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.
 
Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. 
 
If the respirator is the sole means of protection, use a full-face supplied air respirator. 
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. 
Do not let product enter drains.
Discharge into the environment must be avoided.
 
Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions. 
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
 
Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company. 
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.
 
 
 

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