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Ethyl Diglycol (DEGEE) is also known as diethylene glycol monoethyl ether, a clear, colorless, slightly viscous hygroscopic liquid with a mild, pleasant odor.
Ethyl Diglycol is a glycol ether solvent derived from ethylene oxide and ethanol, featuring both ether and alcohol functionality.
Ethyl Diglycol is widely used as a high-boiling, low-volatility solvent, carrier, wetting agent, plasticizer, and humectant in cosmetics, pharmaceuticals, coatings, inks, and agrochemical formulations.
CAS Number: 111‑90‑0
EC Number: 203‑919‑7 (also 203‑937‑5)
Molecular Formula: C₆H₁₄O₃
Molecular Weight: ~134.17 g/mol
Synonyms: Diethylene Glycol Monoethyl Ether, Ethyl Diglycol, DEGEE, Ethoxydiglycol, Carbitol, Carbitol Cellosolve, Transcutol®, Dioxitol, Polysolv DE, Dowanol DE, Ethyl carbitol, Di‑ethylene glycol ethyl ether, Diglycol Monoethyl Ether, Ethoxy Diglycol, Ethyldiglycol, Ethyldiglycol Ether, Ethylene Diglycol Monoethyl Ether, 2‑(2‑Ethoxyethoxy)ethanol, 3,6‑Dioxa‑1‑octanol, Dioxytol, DGEE, DE Solvent, Eastman™ DE Solvent, Solvosol, Chemical DE Solvent, Ethylene Diglycol Ethyl Ether, Monoethyl Ether of Diethylene Glycol, Ethanol, 2,2′‑oxybis‑monoethyl Ether, Ethylene Diglycol Mono‑ethyl Ether, EDGE, Ektasolve DE, EMKANOL DEG, APV Carbitol, Cellosolve DE, Diglycol Mono‑ethyl Ether, Poly‑Solv DE, Solvolsol, Ethyldiglycol Mix, Karbitol, 2‑(2‑Ethoxyethoxy)ethanol, Ethyl Diglycol, Diethylene Glycol Monoethyl Ether, 2-(2‑Ethoxyethoxy)ethanol, Carbitol, Transcutol, Ethoxydiglycol, Dowanol DE, DEGEE
APPLICATIONS
Ethyl Diglycol (DEGEE) is used in personal care products as a solvent for active ingredients.
Ethyl Diglycol (DEGEE) is utilized in hair dyes to dissolve colorants and ensure uniform application.
Ethyl Diglycol (DEGEE) is added to perfumes and fragrances for its excellent solvency and low odor.
Ethyl Diglycol (DEGEE) is used in skin creams and lotions to enhance the penetration of actives.
Ethyl Diglycol (DEGEE) is included in sunscreen formulations to improve solubility of UV filters.
Ethyl Diglycol (DEGEE) is employed in deodorants for its fast-drying and non-sticky nature.
Ethyl Diglycol (DEGEE) is used in facial cleansers and toners as a carrier for active agents.
Ethyl Diglycol (DEGEE) is used in makeup removers for its solvent and mild degreasing properties.
Ethyl Diglycol (DEGEE) is used in topical pharmaceutical formulations for enhanced delivery.
Ethyl Diglycol (DEGEE) is used in insect repellents as a solvent and carrier for actives.
Ethyl Diglycol (DEGEE) is used in industrial coatings for its low volatility and water solubility.
Ethyl Diglycol (DEGEE) is used in textile printing inks for consistent pigment dispersion.
Ethyl Diglycol (DEGEE) is used in water-based paints to improve flow and leveling.
Ethyl Diglycol (DEGEE) is used in water-based adhesives for better viscosity control.
Ethyl Diglycol (DEGEE) is applied in cleaning products as a coupling agent and solvent.
Ethyl Diglycol (DEGEE) is used in printing inks for improved wetting and film formation.
Ethyl Diglycol (DEGEE) is used in floor polishes to enhance gloss and spreadability.
Ethyl Diglycol (DEGEE) is used in air fresheners as a solvent for fragrance oils.
Ethyl Diglycol (DEGEE) is used in surface disinfectants for its compatibility with biocides.
Ethyl Diglycol (DEGEE) is used in chemical synthesis as a reaction medium.
Ethyl Diglycol (DEGEE) is included in anti-corrosion fluids for its solvency and water miscibility.
Ethyl Diglycol (DEGEE) is used in brake fluids and coolants due to its hygroscopic nature.
Ethyl Diglycol (DEGEE) is used in metal cleaners and degreasers for its solvent properties.
Ethyl Diglycol (DEGEE) is used in agricultural formulations as a solvent for pesticides.
Ethyl Diglycol (DEGEE) is used in leather finishing agents for smooth and even coating.
Ethyl Diglycol (DEGEE) is used in automotive care products for cleaning and polishing effects.
Ethyl Diglycol (DEGEE) is used in glass and window cleaners as a streak-free solvent.
Ethyl Diglycol (DEGEE) is used in inkjet printer inks for pigment dispersion and flow control.
Ethyl Diglycol (DEGEE) is used in latex-based products to improve flexibility and film formation.
Ethyl Diglycol (DEGEE) is used in pigment pastes for high dispersion stability.
Ethyl Diglycol (DEGEE) is used in cosmetic serums as a fluidizing agent.
Ethyl Diglycol (DEGEE) is used in pharmaceutical sprays for fine mist formation.
Ethyl Diglycol (DEGEE) is used in household cleaners to dissolve greasy and oily residues.
Ethyl Diglycol (DEGEE) is used in chemical intermediates as a process aid.
Ethyl Diglycol (DEGEE) is used in room sprays for even fragrance distribution.
Ethyl Diglycol (DEGEE) is used in floor cleaners for its solvent and coupling action.
Ethyl Diglycol (DEGEE) is used in shoe polishes for better shine and consistency.
Ethyl Diglycol (DEGEE) is used in shaving gels for improved texture and glide.
Ethyl Diglycol (DEGEE) is used in bath products for dissolving oil-soluble vitamins and scents.
Ethyl Diglycol (DEGEE) is used in medical disinfectants for better delivery of active agents.
Ethyl Diglycol (DEGEE) is used in ink formulations for fountain pens and markers.
Ethyl Diglycol (DEGEE) is used in lubricants for its solvency and spreading characteristics.
Ethyl Diglycol (DEGEE) is used in wax emulsions for a smoother finish.
Ethyl Diglycol (DEGEE) is used in corrosion inhibitors for its water-solubility and stability.
Ethyl Diglycol (DEGEE) is used in heat transfer fluids for thermal stability.
Ethyl Diglycol (DEGEE) is used in metalworking fluids as a lubricant carrier.
Ethyl Diglycol (DEGEE) is used in electroplating baths to regulate viscosity.
Ethyl Diglycol (DEGEE) is used in dental products for its mildness and solvency.
Ethyl Diglycol (DEGEE) is used in cosmetic emulsions for consistency and performance.
Ethyl Diglycol (DEGEE) is used in veterinary topical formulations for enhanced skin delivery.
Ethyl Diglycol is used in cosmetics, personal care, and pharmaceuticals as a solvent, humectant, carrier, penetration enhancer, and stabilizer.
Ethyl Diglycol is a common solvent for resins, nitrocellulose, dyes, inks, and coatings, improving flow, gloss, and drying properties.
Ethyl Diglycol acts as a plasticizer and wetting agent in plastics, sealants, adhesives, elastomers, rubber processing, and concrete additives.
Ethyl Diglycol is used in cleaning products and offset printing as a solvent and wetting/dispersing agent.
Ethyl Diglycol finds use in brake fluids and heat transfer fluids due to its low freezing point and viscosity behavior at low temperature.
DESCRIPTION
Ethyl Diglycol (DEGEE), also known as diethylene glycol monoethyl ether, is a clear, hygroscopic liquid.
Ethyl Diglycol (DEGEE) has excellent solvency for polar and nonpolar compounds.
Ethyl Diglycol (DEGEE) is fully miscible with water and many organic solvents.
Ethyl Diglycol (DEGEE) offers low volatility and a mild odor, making it suitable for sensitive formulations.
Ethyl Diglycol (DEGEE) is widely used in cosmetics, pharmaceuticals, and industrial applications.
Ethyl Diglycol (DEGEE) improves the spreadability and absorption of skincare products.
Ethyl Diglycol (DEGEE) functions as a coupling agent between water and oil-based ingredients.
Ethyl Diglycol (DEGEE) is stable under a wide range of pH and temperature conditions.
Ethyl Diglycol (DEGEE) is valued for its role in dissolving poorly water-soluble substances.
Ethyl Diglycol (DEGEE) enhances the performance and stability of active ingredients in formulations.
Ethyl Diglycol is synthesized through ethoxylation of ethanol or condensation of diethylene glycol and ethanol.
It is hydrophilic, completely miscible with water and many organic solvents, including alcohols, ethers, ketones, aromatic and aliphatic hydrocarbons.
The liquid is hygroscopic and may oxidize over time in air, forming peroxides under certain conditions.
Ethyl Diglycol is chemically stable and relatively low in toxicity, with oral LD₅₀ exceeding 2000 mg/kg in animals.
PROPERTIES
Chemical Formula: C₆H₁₄O₃
Molecular Weight: ~134.17 g/mol
Appearance: Colorless to nearly colorless clear liquid
Odor: Mildly sweet or pleasant, characteristic ether smell
Density / Specific Gravity: ~0.99 g/cm³ at 20 °C
Melting Point: ~–76 °C
Boiling Point: ~196–202 °C at atmospheric pressure
Flash Point: ~96–99 °C (open/closed cup)
Vapor Pressure: ~0.12–0.16 mmHg at 20 °C
Refractive Index: ~1.427 (n₂₀/D)
Viscosity: ~3.8 mPa·s @ 20 °C
Solubility: Fully miscible in water and in solvents such as alcohols, ethers, ketones, and hydrocarbons
Log P: ~–0.54 indicating high polarity
Stability: Stable under normal atmospheric conditions; sensitive to oxidation over time
Storage Conditions: Store in well-sealed containers below 30 °C under inert atmosphere, protected from moisture and light
FIRST AID
Inhalation:
Move person to fresh air.
If symptoms occur, seek medical attention.
Skin Contact:
Wash with soap and water.
Remove contaminated clothing.
Seek medical advice if irritation persists.
Eye Contact:
Rinse thoroughly with water for at least 15 minutes.
Seek medical evaluation if irritation continues.
Ingestion:
Rinse mouth.
Do not induce vomiting.
Seek medical attention if discomfort or symptoms develop.
Note to Physicians:
Treat symptomatically; DEGEE has low acute toxicity and no specific antidote is known.
HANDLING AND STORAGE
Handling:
Use in well-ventilated areas.
Wear gloves, goggles, and protective clothing.
Avoid inhalation of vapor or mist and minimize dust.
Spill Response:
Absorb with inert material and ventilate area.
Dispose according to local environmental regulations.
Storage:
Store in sealed containers below 30 °C in a dry, cool, well-ventilated area.
Protect from moisture, strong oxidants, high heat, and direct sunlight.
Precautions:
Avoid mixing with strong acids or oxidizers due to risk of peroxide formation.
Use explosion-proof equipment when handling vapors.
