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ETHYL DIGLYME (DIETHYLENE GLYCOL METHYL ETHYL ETHER)

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) found that carbonyl and ether groups in the absorbents improved CO2 solubility, and the carbonyl group was more effective than the ether group.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) could be synthesized by reacting 1, 4-dioxane with diethyl ether. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether), is an organic solvent used to study the activities of enzymes in aqueous organic mixtures. 

CAS Number: 112-36-7
Molecular Formula: C8H18O3
Molecular Weight: 162.23
EINECS Number: 203-963-7

Synonyms: Diglyme, 111-96-6, 2-Methoxyethyl ether, Bis(2-methoxyethyl) ether, 1-Methoxy-2-(2-methoxyethoxy)ethane, DIETHYLENE GLYCOL DIMETHYL ETHER, Di(2-Methoxyethyl) ether, Dimethyl carbitol, 2,5,8-Trioxanonane, Ether, bis(2-methoxyethyl), (2-Methoxyethyl) ether, Dimethoxydiglycol, Bis(2-methoxyethyl)ether, Glyme 2, Diglycol methyl ether, Ethane, 1,1'-oxybis[2-methoxy-, Diethyl glycol dimethyl ether, 2-(2-Methoxyethoxy)-1-methoxyethane, 1,1'-Oxybis(2-methoxyethane), NSC 59726, Glyme-2, diethylene glycol dimethylether, diethyleneglycol dimethyl ether, Ethanol, 2,2'-oxybis-, dimethyl ether, 2,2'-oxybis(1-methoxyethane), DTXSID1024621, Ethane, 1,1'-oxybis(2-methoxy-, 2,2'-oxybis[1-(methyloxy)ethane], M4BH3X0MVZ, 1,1'-oxybis[2-methoxyethane], Methyldiglyme, CHEBI:46784, NSC-59726, Diethylene Glycol Dimethyl Ether(Diglyme), Dimethyldiglycol, CH3-O-CH2-CH2-O-CH2-CH2-O-CH3, DTXCID604621, 2-methoxyethylether, CAS-111-96-6, HSDB 72, M2M, CCRIS 6212, EINECS 203-924-4, UNII-M4BH3X0MVZ, MFCD00008503, diethyleneglycoldimethylether, BRN 1736101, Dimethyldigol, dimethyl digol, methyl diglyme, Dimethylcarbitol, AI3-28583, methoxyethyl ether, (Diglyme), 2,8-Trioxanonane, Diglyme, 1-Methoxy-2-(2-methoxyethoxy)ethane, Bis(2-methoxyethyl)ether, Diethylene glycol dimethyl ether, 2-methoxylethyl ether, 2-methyoxyethyl ether, (2-methoxyethyl)ether, HISOLVE MDM, bis(2methoxyethyl)ether, DIGLYME [MI], Dimethoxydiethylene glycol, di-(2-methoxyethyl)ether, SCHEMBL398, EC 203-924-4, bis-(2-methoxy ethyl)ether, bis-(2-methoxyethyl) ether, bis-(2-methoxy ethyl) ether, Ethane,1'-oxybis[2-methoxy-, diethylene-glycol dimethyl ether, CH3OCH2CH2OCH2CH2OCH3, 1,1'-Oxybis(2-methoxy)ethane, CHEMBL1234162, 2,2'-Oxybisethanol dimethyl ether, NSC59726, Bis(2-methoxyethyl) Ether, Reagent, Ethanol,2'-oxybis-, dimethyl ether, Tox21_202340, Tox21_300077, STL280534, 1-(2-methoxyethoxy)-2-methoxyethane, 1-methoxy-2-(2-methoxyethoxyl)ethane, AKOS000120199, DB02935, BIS(2-METHOXYETHYL) ETHER-D14, 1-Methoxy-2-(2-methoxyethoxy)ethane #, NCGC00247897-01, NCGC00247897-02, NCGC00253963-01, NCGC00259889-01, DB-060140, B0498, CS-0017205, NS00000296, EN300-19205, D72523, DIETHYLENE GLYCOL DIMETHYL ETHER [HSDB], Q865952, Diethylene glycol dimethyl ether, analytical standard, Diethylene glycol dimethyl ether, anhydrous, 99.5%, J-509864, Q-200977, Diethylene glycol dimethyl ether, ReagentPlus(R), 99%, F1908-0129, Z104473160, Diethylene glycol dimethyl ether stabilized with 100ppm BHT, Diethylene glycol dimethyl ether, Vetec(TM) reagent grade, 98%, Diethylene glycol dimethyl ether, puriss. p.a., >=99.5% (GC), Diethylene glycol dimethyl ether, spectrophotometric grade, >=99%, InChI=1/C6H14O3/c1-7-3-5-9-6-4-8-2/h3-6H2,1-2H, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE(STABILIZED WITH 0.01%BHT), Diethylene glycol dimethyl ether, puriss., absolute, over molecular sieve (H2O <=0.005%), >=99.5% (GC), 1,1’-oxybis(2-ethoxy-ethan, diethyldiethyleneglycol, Diethyldigol, diethyleneglycoldlethylether, Diethylether diethylenglykolu, diethyletherdiethylenglykolu,Ethane, 1,1'-oxybis*2-ethoxy-,Ethane,1,1’-oxybis[2-ethoxy-

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a solvent for reactions performed at higher temperatures. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the following products: inks and toners, paper chemicals and dyes, pH regulators and water treatment products and laboratory chemicals.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the following areas: health services and scientific research and development. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used for the manufacture of: pulp, paper and paper products. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a scrubbing medium to absorb carbonyl sulfide (COS), an impurity in petroleum refineries. 
It could be used as an absorbent for CO2. 

This absorbent has a high boiling point (462 K, in SciFinder), indicating that energy for absorbent regeneration and loss were saved. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the following products: inks and toners and paper chemicals and dyes.
Other release to the environment of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is likely to occur from: indoor use.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is also used for the removal of water from gas streams (dehydration).
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is not flammable, unless preheated. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is an organic compound with the formula (HOCH2CH2)2O. 

It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is miscible in water, alcohol, ether, acetone, and ethylene glycol. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a widely used solvent. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) can be a contaminant in consumer products.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used as a building block in organic synthesis, e.g. of morpholine and 1,4-dioxane. 
It is a solvent for nitrocellulose, resins, dyes, oils, and other organic compounds. 

It is a humectant for tobacco, cork, printing ink, and glue.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is also a component in brake fluid, lubricants, wallpaper strippers, artificial fog and haze solutions, and heating/cooking fuel.
In personal care products (e.g. skin cream and lotions, deodorants), Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is often replaced by selected Diethylene Glycol Methyl Ethyl Ethers. 

A dilute solution of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) can also be used as a cryoprotectant; however, ethylene glycol is much more commonly used.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used for the manufacture of: chemicals, plastic Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) 's production and use as a high boiling reaction medium, and as a solvent for nitrocellulose, lacquers, resins, and organic syntheses may result in its release to the environment through various waste streams. 
If released to air, a vapor pressure of 0.52 mm Hg at 25 °C indicates Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) will exist solely as a vapor in the atmosphere. 

Vapor-phase Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 14 hours. 
If released to soil, Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is expected to have very high mobility based upon an estimated Koc of 39. 
Volatilization from moist soil surfaces is not expected to be an important fate process based upon an estimated Henry's Law constant of 1.1X10-7 atm-cu m/mole.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) may volatilize from dry soil surfaces based upon its vapor pressure. 
Biodegradation of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is not expected to be an important fate process in soil or water based on biodegradation studies conducted with sewage seed. 
If released into water, Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. 

Volatilization from water surfaces is not expected to be an important fate process based upon this compound's estimated Henry's Law constant. 
An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. 
Occupational exposure to Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) may occur through inhalation and dermal contact with this compound at workplaces where Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)is produced or used. 

Monitoring data indicate that the general population may be exposed to Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)via inhalation of ambient air, ingestion of drinking water, and dermal contact with this compound and other products containing Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether). 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is considered to be a safe and tolerable pharmaceutical-grade glycol ether when used at 99.9% purity.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) also acts as an intracutaneous depot for multiple drugs to reach different layers of the skin. 
The solvent is massively gaining demand in dermatology sector as Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) has the ability to penetrate through the eisoderm of the skin and aid in healing the root cause. 
Owing to these factors, the product is anticipated to witness high growth in pharmaceutical and personal care application in near future.

Ethylene oxide, which is precursor in manufacturing of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether), is highly regulated by multiple regulatory authorities such as U.S. EPA. 
These regulations impact the production and industrial consumption of ethylene oxide, thus affecting the entire manufacturing cycle of ethylene oxide-based products. 

Currently, U.S. is one of the major producers of ethylene oxide owing to abundant availability of feedstock. 
However, increased restrictions on Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)s are anticipated to hinder its production, which, in turn, is expected to have a negative impact on Diethylene Glycol Methyl Ethyl Ethermanufacturers.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether), is a chemical compound used primarily as a solvent. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is an ethylene glycol ether derivative, structurally related to other glycol ethers like Diglyme, but with one methyl group replaced by an ethyl group.
Other release to the environment of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the following products: inks and toners.

Release to the environment of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) can occur from industrial use: formulation of mixtures.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the following products: inks and toners, paper chemicals and dyes, pH regulators and water treatment products and laboratory chemicals.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the following areas: printing and recorded media reproduction and scientific research and development.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used for the manufacture of: chemicals.
In addition, this absorbent is chemically and thermally stable, non-corrosive, and has low density and viscosity. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is rich in philic-CO2 groups, which makes Diethylene glycol diethyl ether more effective for CO2 capture.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is involved in the preparation of nitrocellulose, resins, and adhesives. 
Release to the environment of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) can occur from industrial use: in the production of articles, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.
With special structure, chemical stability and non-toxicity, Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is usually used in the production of water-based coating, special ink and special binder. 

Besides, with excellent solubility, it is often used to produce cleaning agent and paint remover, to recycle and re-process the old high molecular material.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) has a higher boiling point, viscosity, and specific gravity. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is the raw material used in the production of polyester fiber, PET resins, alkyds, and unsaturated polyesters.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the manufacture of unsaturated polyester resins, polyurethanes and plasticizers.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a water-soluble liquid, boiling point 245 C, and is soluble in many organic solvents.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is produced by the partial hydrolysis of ethylene oxide. 

Depending on the conditions, varying amounts of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) and related glycols are produced. 
The resulting product is two ethylene glycol molecules joined by an ether bond, Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is derived as a co-product with ethylene glycol and triethylene glycol. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used as a dehydrating agent for natural gas; a raw material for the production of plasticizers and polyester resins; a humectant; a textile lubricant and coupling agent; a solvent in textile dyeing and printing; a constituent of hydraulic fluids; a plasticizer for paper, cork and synthetic sponges; a solvent in printing inks; a raw material for the production of esters used as emulsifiers, demulsifiers, and lubricants; and a selective solvent for aromatics in petroleum refining.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is the second member of a homologous series of dihydroxyalcohols.
The markets for Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) products are polyester fibres, polyethylene terephthalate (PET) plastics, coolants in automobile antifreeze, and resins. 
The excellent humectant (hygroscopicity) property of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) also makes it ideal for use in fibres treatment, paper, adhesives, printing inks, leather and cellophane.

Melting point: -44.3 °C
Boiling point: 180-190 °C(lit.)
Density: 0.909 g/mL at 25 °C(lit.)
vapor density: 5.6 (vs air)
vapor pressure: 0.5 mm Hg ( 20 °C)
refractive index: n20/D 1.412(lit.)
Flash point: 160 °F
storage temp.: Store below +30°C.
solubility: Chloroform (Sparingly), Methanol (Slightly)
form: Liquid
color: Clear
Relative polarity: 3.9
explosive limit: 6.2%
Water Solubility: SOLUBLE
λmax: λ: 260 nm Amax: 1.00
λ: 300 nm Amax: 0.10
λ: 320 nm Amax: 0.04
λ: 350-400 nm Amax: 0.01
Merck: 14,3118
BRN: 1699259
Dielectric constant: 5.7000000000000002
Stability: Stable. Combustible. Incompatible with strong oxidizing agents. May form peroxides on exposure to air - test for their presence before heating.
InChIKey: RRQYJINTUHWNHW-UHFFFAOYSA-N
LogP: 0.39 at 25℃

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is an excellent reagent for converting compatible carboxylic acids to ethyl esters. 
Such carboxylic acids, refluxed neat in excess TEOF until low-boilers cease evolution, are quantitatively converted to the ethyl esters, without need for extraneous catalysis.
Alternatively, added to ordinary esterifi cations using catalytic acid and ethanol, TEOF helps drive esterification to completion by converting the byproduct water formed to ethanol and ethyl formate.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) are organic compounds in which an oxygen atom is connected to two carbon groups. 
Unlike alcohols, ethers are fairly unreactive (except towards combustion).
They are very common organic solvents, and some ethers also make good anesthetics. 

Simple ethers are named by naming the alkyl groups in alphabetical order and adding the word "ether" to the end. 
In more complicated ethers, the ether group is named as an alkoxy substituent, in which the "yl" ending of alkyl groups is replaced by "oxy." 
For example, a methyl group attached to an oxygen, OCH3, is named as a methoxy group. 

In cyclic ethers, the prefix oxa- is used to indicate replacement of a carbon by an oxygen. 
Since ethers do not have a hydrogen connected to the oxygen atoms, they are not capable of forming hydrogen bonds to each other.
Thus, their boiling points are similar to those of alkanes of comparable molecular mass. 

For example, propane, dimethyl ether, and ethanol have very similar molecular masses, but drastically different boiling points: Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) forms explosive peroxides on prolonged exposure to air.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) decomposition products may be sensitive to shock. 
The bulk chemical is stable for 2 weeks at temperatures up to 140° F when protected from light.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is incompatible with strong oxidizers. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is also incompatible with strong acids.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) may react with peroxides, oxygen, nitric acid and sulfuric acid. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)s are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol commonly used in paints and cleaners.
These solvents typically have a higher boiling point, together with the favorable solvent properties of lower-molecular weight ethers and alcohols. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)s are either "e-series" or "p-series" glycol ethers, depending on whether they are made from ethylene oxide or propylene oxide, respectively. 
Typically, e-series Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)s are found in pharmaceuticals, sunscreens, cosmetics, inks, dyes and water-based paints, while p-series glycol ethers are used in degreasers, cleaners, aerosol paints and adhesives. 
Both E-series glycol ethers and Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)s can be used as intermediates that undergo further chemical reactions, producing glycol diethers and glycol ether acetates. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)s are marketed as having lower toxicity than the E-series.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)s are water-soluble, biodegradable and only a few are considered toxic.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is anticipated that this common cosmetic ingredient will be a component in numerous future prescription topical products approved for the US market. 

Dermatologists are already treating patients that apply products containing 5–40% of this solvent multiple times each day.
The Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) are used widely as solvents for resins, lacquers, paints, varnishes, dyes and inks, as well as components of painting pastes, cleaning compounds, liquid soaps, cosmetics and hydraulic fluids. 
Propylene and butylene glycol ethers are valuable as dispersing agents and as solvents for lacquers, paints, resins, dyes, oils and greases.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the manufacture of unsaturated polyester resins, polyurethanes and plasticizers.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a water-soluble liquid; boiling point 245 C; soluble in many organic solvents.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used as a humectant in the tobacco industry and in the treatment of corks, glue, paper and cellophane.

The industry generally operates to maximize MEG production. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is by far the largest volume of the glycol products in a variety of applications. 
Availability of Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) will depend on demand for derivatives of the primary product, ethylene glycol, rather than on Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) market requirements. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether), HO(C2H4O)3H, is a colourless, odourless, non-volatile, and hygroscopic liquid.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is characterised by two hydroxyl groups along with two ether linkages, which contribute to its high water solubility, hygroscopicity, solvent properties and reactivity with many organic compounds.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the synthesis of morpholine and 1,4-dioxane. 

TEG is displacing Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) in many of these applications on account of its lower toxicity. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) finds use as a vinyl plasticizer, as an intermediate in the manufacture of polyester resins and polyols, and as a solvent in many miscellaneous applications.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)is derived as a coproduct in the manufacture of ethylene glycol from ethylene oxide, and from "onpurpose" Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) production using Diethylene Glycol Monoethyl Ether. 

Some capacities are based on total capacity for ethylene glycols.
The main uses for Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) depend upon its hygroscopic properties. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) as dehumidifiers and, when volatilized, as an air disinfectant for bacteria and virus control.

Diethylene Glycol Monoethyl Ether, having high boiling point and affinity for water, are employed as liquid desiccant for the dehydration of natural gas. 
The dehydration means the removal of water vapor in refinery tower so that dry hydrocarbon gases can exit from the top of the tower. 
There are wide range of glycol ethers which have bifunctional nature of ether and alcohol. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) are monoether derivatives of ethylene glycol. 
They are excellent solvents, having solvent properties of both ethers and alcohols.
Volatilization from water Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is not expected to be an important fate process based upon this compound's estimated Henry's Law constant.

An estimated Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) of 3 suggests the potential for bioconcentration in aquatic organisms is low.
Occupational exposure to Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) may occur through inhalation and dermal contact with this compound at workplaces where Ethyl diglyme is produced or used.
Monitoring data indicate that the general population may be exposed to Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) via inhalation of ambient air, ingestion of drinking water, and dermal contact with this compound and other products containing Ethyl diglyme.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether)'s production and use as a high boiling reaction medium, and as a solvent for nitrocellulose, lacquers, resins, and organic syntheses may result in its release to the environment through various waste streams(SRC).
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether), or glymes, are aprotic, saturated polyethers that offer high solvency, high stability in strong bases and moderate stability in acid solutions.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) solvate cations, increasing anion reactivity, and thus can increase both selectivity and reaction rates.
Most Ethyl diglymeare water-soluble, but a range of solubility and boiling points are available.
The polyether structure produces only weak associations between glyme molecules, and is responsible for the low viscosity and excellent wetting properties of these solvents.

A further structural feature of Ethyl diglyme that contributes significantly to their usefulness involves the arrangement of oxygen atoms, as ether linkages, at two-carbon intervals.
The model of the Ethyl diglyme molecule (picture above) illustrates this periodic recurrence of oxygen atoms separated by two carbon atoms.
This steric arrangement, analogous to that of crown ethers, gives Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) the ability to form complexes with many cations. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) have a wide range of solubilities and boiling points.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) are used as reaction solvents and in closed loop applications such as gas scrubbing and in refrigeration systems.
The higher molecular Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) beginning with ethyl diglyme are suitable for emissive applications such as coatings, inks, adhesives and in cleaning compounds.

The lower molecular Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) should not be used in emissive applications.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is most commonly utilized as a high-performance solvent for both laboratory and industrial applications.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) effectively solvates digital inks and decorative ceramic inks, since Ethyl diglyme is stable enough to withstand the high temperatures of these applications.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is also commonly used on small scales as an extraction solvent for gold from hydrochloric acid media, a process which results in an extremely high concentration of pure gold metal.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) can also be used as an intermediate in the production of siloxane-based adjuvants.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a linear aliphatic diether widely used as a solvent and present as a clear liquid at room temperature with a mild ether odor.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is not known to occur in nature.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is synthesized from ethylene oxide and methanol in the presence of either acidic or basic catalysts.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a clear colorless viscous liquid.

Because of its resistance to strong bases, diglyme is favored as a solvent for reactions of alkali metal reagents even at high temperatures. 
Rate enhancements in reactions involving organometallic reagents, such as Grignard reactions or metal hydride reductions, have been observed when using diglyme as a solvent.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is also used as a solvent in hydroboration reactions with diborane.

It serves as a chelate for alkali meta
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether), is an organic compound with the chemical formula (CH3OCH2CH2)2O. 
It is a colorless liquid with a slight ether-like odor. 

It is a solvent with a high boiling point. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is the dimethyl ether of diethylene glycol. 
The name Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a portmanteau of diglycol methyl ether. 

It is miscible with water as well as organic solvents.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) consists of an ethoxy and a methoxy group attached to an ethylene glycol backbone, making it a dialkyl ether with good solubility properties.
If sodium is used, the ether should be redistilled alone to remove any products which may be formed by the action of sodium on the ether. 

As a preliminary purification, the crude ether (2L) can be refluxed for 12hours with 25mL of conc HCl in 200mL of water, under reduced pressure, with slow passage of N2 to remove aldehydes and other volatile substances. 
After cooling, add sufficient solid KOH pellets (slowly and with shaking until no more dissolves) to give two liquid phases. 
The upper of these is decanted, dried with fresh KOH pellets, decanted, then refluxed over, and distilled from sodium. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) can be passed through (alkaline) alumina prior to purification.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is an organic compound with the formula HC(OC2H5)3. 
This colorless volatile liquid, the ortho ester of formic acid, is commercially available. 

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) may also be prepared from the reaction of sodium ethoxide, formed in-situ from sodium and absolute ethanol, and chloroform: CHCl3 + 3 Na + 
3 EtOH → HC(OEt)3 + 3⁄2 H2 + 3 NaCl Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in the Bodroux-Chichibabin aldehyde synthesis, for example: RMgBr + HC(OC2H5)3 → RC(H)(OC2H5)2 + MgBr(OC2H5) ; RC(H)(OC2H5)2 + H2O → RCHO + 2 C2H5OH . 
In coordination chemistry, Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used to convert metal aquo complexes to the corresponding ethanol complexes: [Ni(H2O)6](BF4)2 + 6 HC(OC2H5)3 → [Ni(C2H5OH)6](BF4)2 + 6 HC(O)(OC2H5) + 6 HOC2H5.

Uses:
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used as a solvent in the synthesis of pharmaceuticals and fine chemicals, facilitating various chemical reactions.
Helps dissolve active ingredients in pharmaceutical formulations, improving their stability and efficacy.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used as a solvent and carrier in cosmetic products, helping to dissolve ingredients and enhance product texture.

Found in creams, lotions, and serums to improve the consistency and application properties.
Included in formulations for various cleaning agents, providing effective removal of grease, grime, and stains.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used in specific applications related to fuel cells, including the dissolution of certain materials or as a part of the electrolyte system.

Utilized in research laboratories for chemical synthesis, extraction, and analysis, where it serves as a versatile solvent.
May be used in formulations for drilling fluids to enhance performance and reduce environmental impact.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used as a solvent in dyeing processes and textile finishing treatments, aiding in the application of dyes and chemicals.

Sometimes used as a solvent in agricultural chemical formulations, helping to dissolve active ingredients and improve application efficiency.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a very useful organic solvent. 
It has a high boiling point and has been used to study the activities of enzymes in aqueous organic mixtures.

Used for dissolving resins, oils, dyes, and waxes in industrial settings, particularly for coatings, inks, and cleaners.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used as a solvent in electronics manufacturing, especially in cleaning and preparation processes.
Sometimes used as a reaction medium in the synthesis of pharmaceuticals and fine chemicals.

Can be used as a solvent in formulations for skincare and cosmetic products.
Due to its chemical stability, Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) may be used in certain specialized solvent applications within the energy sector, such as fuel cell components or related research areas.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used as a solvent for paints, varnishes, and inks, where it helps dissolve and stabilize various components.

Acts as a solvent for adhesive formulations, improving viscosity and application properties.
Employed in cleaning processes for electronic components and circuit boards, effectively removing residues and contaminants.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is used as a solvent in soldering processes to ensure proper wetting and adhesion.

Safety Profile:
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) may cause irritation to the skin, eyes, and respiratory system. 
Chronic exposure could have effects on the liver and kidneys.
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) is a flammable liquid and should be handled away from sources of ignition.

Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) has relatively low acute toxicity, but prolonged or high-level exposure could lead to more significant health concerns.
Care should be taken to prevent spills and leaks, as it can cause environmental contamination if released in significant quantities.

Moderately toxic by ingestion. 
Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) an experimental teratogen. 
Other experimental reproductive effects. 

Flammable when exposed to heat or flame. 
When heated to decomposition Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) emits acrid smoke and irritating fumes.
The European Chemicals Agency lists diglyme as a substance of very high concern (SVHC) as a reproductive toxin.

At higher temperatures and in the presence of active metals diglyme is known to decompose, which can produce large amounts of gas and heat.
This decomposition led to the T2 Laboratories reactor explosion in 2007.
Similar to other glycol ethers, Ethyl Diglyme (Diethylene Glycol Methyl Ethyl Ether) can be hazardous upon prolonged exposure. 

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