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CAS NO:141-43-5
EC NO:205-483-3
Ethyl Monoethanolamine is a clear, colourless to pale yellow liquid with an amine-like odor.
Ethyl Monoethanolamine is completely miscible with water and many other organic solvents.
Specifications:
Appearance : Clear,Colourless Liquid
Colour : 25 APHA max.
Moisture : 0.5% max.
Purity ( GC ) : 99 % min.
Distillation Range : 160 0C – 170 0C
Intermediate used in the production of : Pharmaceuticals.
Ethyl Monoethanolamine is also used in microelectronics.
Also used in preparation of coatings, detergents, Functional fluids & Oil additives.
Ethyl Monoethanolamine (2-aminoethanol, monoethanolamine, ETA, or MEA) is an organic chemical compound with the formula HOCH2CH2NH2 or C2H7NO.The molecule is bifunctional, containing both a primary amine and a primary alcohol.
Ethyl Monoethanolamine is a colorless, viscous liquid with an odor reminiscent of ammonia.
Ethyl Monoethanolamine molecules are a component in the formation of cellular membranes and are thus a molecular building block for life.
Ethyl Monoethanolamine was thought to exist only on Earth and on certain asteroids, but in 2021 evidence was found that Ethyl Monoethanolamine molecules exist in interstellar space.
Derivatives of ethanolamine are widespread in nature; e.g., lipids, as precursor of a variety of N-acylethanolamines (NAEs), that modulate several animal and plant physiological processes such as seed germination, plant–pathogen interactions, chloroplast development and flowering, as well as precursor, combined with arachidonic acid C20H32O2 20:4, ω-6), to form the endocannabinoid anandamide (AEA:C22H37NO2; 20:4, ω-6).
The ethanolamines comprise a group of amino alcohols. A class of antihistamines is identified as ethanolamines, which includes carbinoxamine, clemastine, dimenhydrinate, Chlorphenoxamine, diphenhydramine and doxylamine.
Ethyl Monoethanolamine is produced by treating ethylene oxide with aqueous ammonia; the reaction also produces diethanolamine and triethanolamine. The ratio of the products can be controlled by the stoichiometry of the reactants.
Properties:
Chemical formula: C2H7NO
Molar mass: 61.084 g·mol−1
Appearance: Viscous colourless liquid
Odor: Unpleasant ammonia-like odour
Density: 1.0117 g/cm3
Melting point: 10.3 °C (50.5 °F; 283.4 K)
Boiling point: 170 °C (338 °F; 443 K)
Solubility in water: Miscible
Vapor pressure: 64 Pa (20 °C)[2]
Acidity (pKa): 9.50[]
Refractive index (nD): 1.4539 (20 °C)
Ethyl Monoethanolamine is a first generation monoethanolamine with antihistaminic property.
Ethyl Monoethanolamine competes with free histamine for binding at the histamine (H)-1 receptor thereby acting as an inverse agonist that combines with and stabilizes the inactive form of the H1-receptor thereby shifting the equilibrium toward the inactive state. This leads to a reduction of the negative symptoms brought on by H1-receptor binding.
Ethyl Monoethanolamine appears as a clear colorless liquid with an odor resembling that of ammonia. Flash point 185°F. May attack copper, brass, and rubber. Corrosive to tissue. Moderately toxic. Produces toxic oxides of nitrogen during combustion.
Ethyl Monoethanolamine is a member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol.
Ethyl Monoethanolamine has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite.
Ethyl Monoethanolamine is a primary amine, a primary alcohol and a member of ethanolamines.
Ethyl Monoethanolamine is a conjugate base of an ethanolaminium(1+).
Industry Uses:
-Agricultural chemicals (non-pesticidal)
-Corrosion inhibitors and anti-scaling agents
-Functional fluids (closed systems)
-Functional fluids (open systems)
-Intermediates
-Ion exchange agents
-Lubricants and lubricant additives
-Plating agents and surface treating agents
-Processing aids, not otherwise listed
-Processing aids, specific to petroleum production
-Solvents (which become part of product formulation or mixture)
Consumer Uses:
-Agricultural products (non-pesticidal)
-Cleaning and furnishing care products
-Electrical and electronic products
-Floor Care Chemicals
-Gas treating to scrub hydrogen sulfide and carbon dioxide from natural gas streams
-Lubricants and greases
-Metal products not covered elsewhere
-Paper products
-Plastic and rubber products not covered elsewhere
-used in products which are used as cleaners in plating processes, as paint strippers, used as cleaners used in products for a variety of applications for surface treatments, examples of final uses are automotive and machinery.
Ethyl Monoethanolamine is used to manufacture wet-adhesion additives for latex paints, in the manufacture of fabric softeners, fuel additives and lube oil additives.
Ethyl Monoethanolamine is an intermediate in the manufacture of chelating agents and surfactants.
Applications
Ethyl Monoethanolamine is commonly called monoethanolamine or MEA in order to be distinguished from diethanolamine (DEA) and triethanolamine (TEA).
Ethyl Monoethanolamine is used as feedstock in the production of detergents, emulsifiers, polishes, pharmaceuticals, corrosion inhibitors, chemical intermediates.
A clear liquid with an ammonia-like odor.
Ethyl Monoethanolamine is toxic, flammable, and corrosive.
Uses: In sweetening natural gas and coal gas, as soaps or amides in heavy-duty detergents, in the production of ethylene amines, in aqueous solutions for scrubbing certain acidic gases, in feedstock in the production of detergents, emulsifiers, polishes, pharmaceuticals, corrosion inhibitors, and chemical intermediaries.
Ethyl Monoethanolamine belongs to the group of ethanolamines and is used in the production of detergents and cleaning agents, amongst others.
Product description
Ethyl Monoethanolamine is available as an anhydrous liquid.
Ethyl Monoethanolamine has an ammonia-like odor and is miscible with water, alcohol and ether.
Applications/uses:
-Electronic chemicals
-Herbicides - intermediate for atrazine
-Herbicides - intermediate for other
Ethyl Monoethanolamine has several important industrial uses: as a “scrubber” to remove carbon dioxide, hydrogen sulfide, and other acidic pollutants from waste gas streams; as a starting material for manufacturing surfactants, chelating agents, and even pharmaceuticals; as an agent for softening leather; and as an additive for controlling pH in industrial water streams.
Ethyl Monoethanolamine, the first of three organic compounds that can be derived from ammonia by successively replacing the hydrogen atoms with hydroxyethyl radicals (―CH2CH2OH), the others being diethanolamine and triethanolamine.
Ethyl Monoethanolamine, also called 2-aminoethanol or monoethanolamine (MEA), is a viscous, hygroscopic organic chemical compound that is both a primary amine (due to an amino group) and a primary alcohol (hydroxyl group). Used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.
Ethyl Monoethanolamine is widely distributed in biological tissue and is a component of lecithin.
Ethyl Monoethanolamine is the second-most-abundant head group for phospholipids, substances found in biological membranes.
Formula: C2H7NO / H2NCH2CH2OH
Molecular mass: 61.1
Boiling point: 171°C
Melting point: 10°C
Relative density (water = 1): 1.02
Solubility in water: freely soluble
Vapour pressure, Pa at 20°C: 53
Relative vapour density (air = 1): 2.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 85°C c.c.
Auto-ignition temperature: 410°C
Explosive limits, vol% in air: 5.5-17
Octanol/water partition coefficient as log Pow: -1.31 (estimated)
Ethyl Monoethanolamines are present in many consumer products ranging from cosmetics, personal care products and household cleaning products. Both have been linked to liver tumors. The European Commission prohibits diethanolamine (DEA) in cosmetics, to reduce contamination from carcinogenic nitrosamines.
FOUND IN: Soaps, shampoos, hair conditioners and dyes, lotions, shaving creams, paraffin and waxes, household cleaning products, pharmaceutical ointments, eyeliners, mascara, eye shadows, blush, make-up bases, foundations, fragrances, sunscreens
Ethyl Monoethanolamine is also used in messenger molecules such as palmitoylethanolamide, which have an effect on CB1 receptors.
Ethyl Monoethanolamine is used as a scrubber for the removal of methyl bromide. Polyaniline doping ethanolamine is used for modified electrode preparation to measure uric acid in human body with the presence of antiscorbutic acid.
Ethyl Monoethanolamine, also known as aminoethanol or beta-aminoethyl alcohol, is a member of the class of compounds known as 1,2-aminoalcohols. 1,2-aminoalcohols are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom.
Ethyl Monoethanolamine is soluble (in water) and an extremely weak acidic compound (based on its pKa).
Ethyl Monoethanolamine can be found in a number of food items such as daikon radish, caraway, muscadine grape, and lemon grass, which makes ethanolamine a potential biomarker for the consumption of these food products.
Ethyl Monoethanolamines are a family of chemicals that work as surfactants and emulsifying ingredients in personal care products and cleaning products. Common ethanolamines include monoethanolamine (MEA), diethanolamine (DEA) and triethanolamine (TEA).
Ethyl Monoethanolamines are made through a chemical reaction of ethylene oxide with ammonia.
Ethyl Monoethanolamine or also called Monoethanolamine (MEA) is a colorless liquid used mainly in so-called "ammonia-free" hair dyes, to replace it.
Ethyl Monoethanolamine therefore promotes the opening of the scales of the cuticle before any permanent coloring.
Ethyl Monoethanolamine is nevertheless made from ethylene oxide and ammonia.
Ethyl Monoethanolamine is a potential irritant/allergen to mucous membranes and skin.
Restriction in Europe: III/61
The maximum concentrations authorized in cosmetics are as follows:
- Maximum content of secondary amine: 0.5%
Other restrictions:
- Do not use with nitrosating systems
- Minimum purity: 99%
- Maximum content of secondary amine: 0.5% (applies to raw materials)
- Maximum nitrosamine content: 50 micrograms/kg
- Store in nitrite-free containers
Ethyl Monoethanolamines functions (INCI)
pH regulator: Stabilizes the pH of cosmetics
Ethyl Monoethanolamine is a kind of viscous hygroscopic amino alcohol contains both amine and alcohol chemical groups.
Ethyl Monoethanolamine is widely distributed inside the body and is a component of lecithin.
Ethyl Monoethanolamine has many kinds of industrial applications. For example, it can be used in the production of agricultural chemicals including ammonia as well as the manufacturing of pharmaceuticals and detergents.
Ethyl Monoethanolamine can also be used as a surfactant, fluorimetric reagent and removing agent of CO2 and H2S. In pharmaceutical field, ethanolamine is used as a Vascular Sclerosing agent.
Ethyl Monoethanolamine also has antihistaminic property, which alleviates the negative symptoms caused by H1-receptor binding.
Ethyl Monoethanolamines are used widely as intermediates in the production of surfactants, which have become commercially important as detergents, textile and leather chemicals, and emulsifiers. Their uses range from drilling and cutting oils to medicinal soaps and highquality toiletries.
Ethyl Monoethanolamine is used as an absorption agent to remove carbon dioxide and hydrogen sulfide from natural gas and other gases, as a softening agent for hides, and as a dispersing agent for agricultural chemicals.
Ethyl Monoethanolamine is also used in polishes, hair waving solutions, emulsifiers, and in the synthesis of surface-active agents (Beyer et al 1983; Mullins 1978; Windholz 1983).
Ethyl Monoethanolamine is permitted in articles intended for use in the production, processing, or packaging of food (CFR 1981).
Ethyl Monoethanolamine undergoes reactions characteristic of primary amines and of alcohols. Two industrially important reactions of ethanolamine involve reaction with carbon dioxide or hydrogen sulfide to yield water soluble salts, and reaction with long chain fatty acids to form neutral ethanolamine soaps (Mullins 1978).
Ethyl Monoethanolamine is contained in many products, such as metalwork fluids.
Ethyl Monoethanolamine is mainly an irritant. Traces may exist in other ethanolamine fluids.
Chemical Properties
Ethyl Monoethanolamine is a clear, colorless or pale yellow-colored, moderately viscous liquid with a mild, ammoniacal odor.
Ethyl Monoethanolamines can be detected by odor as low as 2-3 ppm.
Physical properties
Colorless, viscous, hygroscopic liquid with an unpleasant, mild, ammonia-like odor. Odor threshold concentration is 2.6 ppm (quoted, Amoore and Hautala, 1983). The lowest taste threshold concentration in potable water at 40 °C was 2.4 mg/L (Alexander et al., 1982).
Uses
Ethyl Monoethanolamine is used as a dispersing agent for agricultural chemicals, in thesynthesis of surface-active agents, as a softening agent for hides, and in emulsifiers,polishes, and hair solutions.
Uses
As a chemical intermediate; corrosion inhibitor; in the production of cosmetics, detergents, paints, and polishes
Uses
Used as buffer; removal of carbon dioxide and hydrogen sulfide from gas mixtures.
Definition
ChEBI: A member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol.
Production Methods
Ethyl Monoethanolamine is prepared commercially by the ammonolysis of ethylene oxide. The reaction yields a mixture of monoethanolamine, diethanolamine, and triethanolamine, which is separated to obtain the pure products.
Ethyl Monoethanolamine is also produced from the reaction between nitromethane and formaldehyde.
About Ethyl Monoethanolamine
Helpful information
Ethyl Monoethanolamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 tonnes per annum.
Ethyl Monoethanolamine is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
Ethyl Monoethanolamine is used in the following products: adhesives and sealants, washing & cleaning products, polishes and waxes, coating products, lubricants and greases, fillers, putties, plasters, modelling clay and inks and toners.
Other release to the environment of Ethyl Monoethanolamine is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Article service life
Release to the environment of Ethyl Monoethanolamine can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and of articles where the substances are not intended to be released and where the conditions of use do not promote release. Other release to the environment of Ethyl Monoethanolamine is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints). Ethyl Monoethanolamine can be found in complex articles, with no release intended: vehicles. Ethyl Monoethanolamine can be found in products with material based on: wood (e.g. floors, furniture, toys), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and plastic (e.g. food packaging and storage, toys, mobile phones).
Widespread uses by professional workers
Ethyl Monoethanolamine is used in the following products: washing & cleaning products, lubricants and greases, metal working fluids, polymers, laboratory chemicals, fuels, inks and toners, leather treatment products and paper chemicals and dyes.
Ethyl Monoethanolamine is used in the following areas: building & construction work, scientific research and development and printing and recorded media reproduction.
Ethyl Monoethanolamine is used for the manufacture of: chemicals and machinery and vehicles.
Other release to the environment of Ethyl Monoethanolamine is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Formulation or re-packing
Ethyl Monoethanolamine is used in the following products: fuels, metal surface treatment products, non-metal-surface treatment products, biocides (e.g. disinfectants, pest control products), pH regulators and water treatment products, laboratory chemicals, photo-chemicals and semiconductors.
Release to the environment of Ethyl Monoethanolamine can occur from industrial use: formulation of mixtures.
Uses at industrial sites
Ethyl Monoethanolamine is used in the following products: metal working fluids, pH regulators and water treatment products, fuels, inks and toners, leather treatment products, paper chemicals and dyes, biocides (e.g. disinfectants, pest control products), laboratory chemicals, lubricants and greases, washing & cleaning products and extraction agents.
Ethyl Monoethanolamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethyl Monoethanolamine is used for the manufacture of: chemicals and electrical, electronic and optical equipment.
Release to the environment of Ethyl Monoethanolamine can occur from industrial use: in processing aids at industrial sites, in the production of articles, of substances in closed systems with minimal release and as an intermediate step in further manufacturing of another substance (use of intermediates).
Manufacture
Release to the environment of Ethyl Monoethanolamine can occur from industrial use: manufacturing of the substance.
IUPAC names
2,2',2" -Nitriloethanol
2-aminoethan-1-ol
2-AMINOETHANOL
2-Aminoethanol
2-aminoethanol
2-Aminoethanol
2-aminoethanol
2-aminoethanol ethanolamine
2-Aminoethanol; Ethanolamine
2-aminoethanol; ethanolamine
2-aminoethanolMEA
2-Aminoethyl alcohol
2-Ethanolamin
Ethanol, 2-amino-
Ethanol,2-amino
Ethanolamin
Ethanolamine
ethanolamine
Ethanolamine
Ethanolamine, 2-Aminoethyl alcohol, Monoethanolamine, ETA, MEA 90, MEA-LCI, MEA
Ethanolamine; monoethanolamine; 2-aminoethanol ...
ethanoloamine
MEA
monoetanolammine
MONOETHANOLAMINE
Monoethanolamine
Monoethanolamine
monoethanolamine
Monoethanolamine (MEA)
Monoethanolamine (MEA) - OR30
Monoethanolamine 99 %
Piperazine Mixture
SYNONYMS:
1,3-Propanediol, 2-methyl- [ACD/Index Name]
141-43-5 [RN]
205-483-3 [EINECS]
2-Aminoethanol [ACD/IUPAC Name]
2-Aminoethanol [German] [ACD/IUPAC Name]
2-Aminoéthanol [French] [ACD/IUPAC Name]
2-aminoethyl alcohol
505944 [Beilstein]
aminoethanol
ETA
etanolamina [Italian]
Ethanol, 2-amino- [ACD/Index Name]
ETHANOLAMINE [Wiki]
MEA 90
MEA-LCI
MFCD00008183 [MDL number]
Monoaethanolamin [German]
monoethanolamine [Wiki]
olamina [Spanish] [INN]
olamine [INN]
olamine [French] [INN]
olaminum [Latin] [INN]
β-aminoethanol
β-aminoethyl alcohol
оламин [Russian] [INN]
أولامين [Arabic] [INN]
乙醇胺 [Chinese] [INN]
12220-07-4 [RN]
12220-09-6 [RN]
1-amino-2-hydroxyethane
1-Aminoethane
2-Amino ethanol
2-AMINO-1-ETHANOL
2-Aminoaethanol [German]
2-Aminoetanolo [Italian]
2-Aminoethan-1,1,2,2-d4-ol
2-Aminoethan-1-Ol
2-Amino-ethanol
