PRODUCTS

ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID)

Ethylenediamine tetra(methylene phosphonic Acid) is used as scale and corrosion inhibitor for steam boiler.
Ethylenediamine tetra(methylene phosphonic Acid) is used scale Inhibitor for circulating cooling water.
Ethylenediamine tetra(methylene phosphonic Acid) is used stabilizer for peroxide.

CAS Number: 1429-50-1
EC / EINECS Number: 215-851-5
MDL Number: MFCD00058893
Molecular Formula: C6H20N2O12P4
Molecular Weight: 436.12 g/mol

SYNONYMS:
{Ethane-1,2-diylbis[nitrilobis(methylene)]}tetrakis(phosphonic acid), Ethylenediamine tetra(methylene phosphonic acid), EDTMP, 1429-50-1, Lexidronam, Ethylenediaminetetra(methylenephosphonic acid), V4CP8RSX7V, BRIQUEST 422-25S, DTXSID3061689, EDTPO, (Ethylenedinitrilo)-tetramethylenephosphonic acid, Ethylenediamine tetra(methylene phosphonic acid), PH540, Ethylenediamine tetrakis(methylene phosphonic acid), PH-540, Phosphonic acid, (1,2-ethanediylbis(nitrilobis(methylene)))tetrakis-, editempa, editempa acid, 68Ga-EDTMP, RefChem:406469, DTXCID9034654, ethylenediaminetetra(methylenephosphonic)acid, N,N,N',N' ethylenediamine tetra(methylene-phosphonic acid), (1,2-ethanediylbis(nitrilobis(methylene)))tetrakisphosphonic acid, 215-851-5, edtmp, EDTMPA, Ethylenebis(nitrilodimethylene)tetraphosphonic acid, ((Ethane-1,2-diylbis(azanetriyl))tetrakis(methylene))tetraphosphonic acid, [2-[bis(phosphonomethyl)amino]ethyl-(phosphonomethyl)amino]methylphosphonic acid, MFCD00058893, N,N,N',N'-Ethylenediaminetetrakis(methylenephosphonic Acid), 61827-49-4, Ethylenediamine tetrakis(methylene phosphonic acid) hexasodium salt, Masquol P 430NA, 22036-77-7, [ethane-1,2-diylbis(nitrilodimethanediyl)]tetrakis(phosphonic acid), [[Ethane-1,2-diylbis(azanetriyl)]tetrakis(methylene)]tetraphosphonic Acid, C6H20N2O12P4, [1,2-Ethanediylbis[Nitrilobis-(Methylene)]]Tetrakis-Phosphonic Acid, EINECS 215-851-5, EINECS 239-204-1, EINECS 263-254-3, UNII-V4CP8RSX7V, SCHEMBL22492, orb2942385, CHEMBL1208647, n,n,n',n'-ethylenediaminetetra(methylenephosphonic acid), N,N,N',N'-Ethylenediaminetetrakis, Ethylenediaminetetrakis(methylenephosphonic acid) hexasodium salt, (Ethane-1,2-diylbis(nitrilobis(methylene)))tetrakisphosphonic acid, BBL000007, Ethylene bis(nitrilodimethylene)tetraphosphonic acid, hexasodium salt, STK368766, AKOS000365812, CS-W009667, FE75418, HY-W008951, ethylendiamintetra(methylenphosphonsaure), Phosphonic acid, (1,2-ethanediylbis(nitrilobis(methylene)))tetrakis-, hexasodium salt, Tetrasodium tetrahydrogen (ethane-1,2-diylbis(nitrilobis(methylene)))tetrakisphosphonate, AS-15020, PD062904, ST011995, SY053136, DB-042657, E0393, NS00009310, E75876, SR-01000944825, Q3045881, SR-01000944825-1, BRD-K54542929-001-01-7, bis(phosphonomethyl){2-[bis(phosphonomethyl)amino]ethyl}amine, ETHYLENEDIAMINE-N,N,N',N'-TETRA(METHYLPHOSPHONIC ACID), {Ethane-1,2-diylbis[nitrilobis(methylene)]}tetrakis(phosphonic acid), EDTMP, [1,2-Ethanediylbis(nitrilobis-(methylene))]tetrakis-phosphonic acid, ETHANEDIYLBIS(NITRILOBIS-(METHYLENE)))TETRAKIS-PHOSPHONIC ACID, (1,2-, Hexasodium dihydrogen (ethane-1,2-diylbis(nitrilobis(methylene)))tetrakisphosphonate, Phosphonic acid, P,P',P'',P'''-(1,2-ethanediylbis(nitrilobis(methylene)))tetrakis-, EDTMP ,Ethylenediamine tetrakis(methylene phosphonic acid) ,[2-[bis(phosphonomethyl)amino]ethyl-(phosphonomethyl)amino]methylphosphonic acid, EDTMP, EDTMPA, Ethylenediamine tetra(methylene phosphonic acid), Ethylenebis(nitrilodimethylene)tetraphosphonic acid, N,N,N′,N′-tetrakis(phosphonomethyl)ethylenediamine, Tetraphosphonic acid, (a phosphonate analog of EDTA), EDTMP, [bis(phosphonomethyl)amino]methylphosphonic acid, {ethane-1,2-diylbis[nitrilobis(methylene)]}tetrakis(phosphonic acid), Ethylenediamine tetra(methylene phosphonic acid, EDTMPA, EDITEMPA, Dequest 2041, EDTMP, EDTMPA, EDTMPA (Solid), Antiscale and inhibitor, Ethylenediamine Tetramethylenephosphonic acid, ethylene diamine tetra-methylene phosphoric aci, Ethylene Diamine Tetra(Methylene Phosphonic Acid), (Ethylenedinitrilo)-tetramethylenephosphonic acid, Ethylene Diamine Tetra (Methylene Phosphonic Acid), N,N,N',N'-Tetrakis(phosphonomethyl)ethylenediamine, (Ethylene-dinitrilo)-tetramethylene phosphonic acid, Ethylenebis(Nitrilodimethylene)Tetraphosphonic Acid, N,N,N,N-Ethylenediaminetetra(methylenephosphonic acid), Ethylene Diamine Tetra (Methylene Phosphonic Acid) Sodium, ETHYLENEDIAMINETETRA(METHYLENEPHOSPHONICACID)SODIUM(EDTMPS), [ethane-1,2-diylbis(nitrilodimethanediyl)]tetrakis(phosphonic acid), N,N,N',N'-Ethylenediaminetetrakis(methylenephosphonic Acid) Hydrate, Phosphonic acid,P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, Phosphonic acid,[ethylenebis(nitrilodimethylene)]tetra-, Phosphonic acid,[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, P,P′,P′′,P′′′-[1,2-Ethanediylbis[nitrilobis(methylene)]]tetrakis[phosphonic acid], Ethylenediaminetetra(methylenephosphonic acid), Ethylenediaminetetrakis(methylphosphonic acid), Ethylenediaminotetra(methylenephosphonic acid), [Ethylenebis(nitrilodimethylene)]tetraphosphonic acid, Ethylenediaminetetrakis(methylenephosphonic acid), Ethylenediamine-N,N,N′,N′-tetra(methylphosphonic acid), Ethylenedi(nitrilodimethylene)tetraphosphonic acid, Dequest 2041, N,N,N′,N′-Tetrakis(phosphonomethyl)ethylenediamine, Dequest 2040, Editempa, EDTF, EDPA, EDTPA, Wayplex 45K, EDTMP, Ethylenediamine-N,N,N′,N′-tetrakis(methylenephosphonic acid), EDPA (chelating agent), Cublen 3115, EDTPH, EDTMPA, Ethylenediaminetetramethylenephosphonate, Briquest 422-25S, PH 540, Chelest PH 540, Chelating agent 540, Cublen E 950, EDTMPS, ([[2-(Bis-phosphonomethyl-amino)-ethyl]-phosphonomethyl-amino]-methyl)-phosphonic acid, [2-[Bis(phosphonomethyl)amino]ethyl-(phosphonomethyl)amino]methylphosphonic acid, 103333-76-2, 54579-31-6, 66300-26-3, 85497-53-6, 244775-21-1, ETHYLENEDIAMINETETRA(METHYLENEPHOSPHONICACID)SODIUM(EDTMPS), N,N,N’,N’-Tetrakis(phosphonomethyl)ethylenediamine, tetraphosphonic acid, N,N,N’,N’-ETHYLENEDIAMINETETRA(METHYLENEPHOSPHONIC ACID), ETHYLENEDIAMINE TETRA(METHYLENEPHOSPHONIC ACID), Phosphonic acid, P,P’,P”,P”’-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, Ethylenediaminetetra(methylenephosphonic acid) (EDTMP)

EDTMP or ethylenediamine tetra(methylene phosphonic acid) is a phosphonic acid.
Ethylenediamine tetra(methylene phosphonic Acid) has chelating and anti corrosion properties.
Ethylenediamine tetra(methylene phosphonic Acid) is the phosphonate analog of EDTA.

Ethylenediamine tetra(methylene phosphonic Acid) is classified as a nitrogenous organic polyphosphonic acid.
Ethylenediamine tetra(methylene phosphonic acid), commonly known as EDTMP, is a phosphonic acid characterized by its chelating and anti-corrosion properties.

As a nitrogenous organic polyphosphonic acid, Ethylenediamine tetra(methylene phosphonic Acid) serves as the phosphonate analog of ethylenediaminetetraacetic acid (EDTA) and is typically delivered in its sodium salt form, which exhibits high solubility in water.
Ethylenediamine tetra(methylene phosphonic Acid) is notable for its ability to inhibit scale formation and corrosion in various industrial applications, outperforming traditional inorganic polyphosphates by three to five times in corrosion inhibition efficiency.

Ethylenediamine tetra(methylene phosphonic Acid) has a high capacity for chelating metal ions.
The complex constant with Cu is the largest in all chelating agents including EDTA.
Ethylenediamine tetra(methylene phosphonic Acid) is a kind of high-pure grade reagent and innocuous.

The chelating capacity of Ethylenediamine tetra(methylene phosphonic Acid) largely exceeds that of EDTA and DTPA and can replace EDTA as a chelating agent in almost any situation.
Ethylenediamine tetra(methylene phosphonic Acid) is a kind of high-pure grade reagent and innocuous.

Ethylenediamine tetra(methylene phosphonic Acid) is a white crystal powder at room temperature, with melting point 215-217℃, hard to be dissolved in water, the solubility is less than 5% at room temperature, easy dissolved in ammonia.
Ethylenediamine tetra(methylene phosphonic Acid), commonly referred to as EDTMPA, is a phosphonic acid derivative characterized by its four methylenephosphonic acid groups attached to an ethylenediamine backbone.

Overall, Ethylenediamine tetra(methylene phosphonic Acid) is valued for its multifunctional properties, making it a versatile compound in both industrial and research settings.
Ethylenediamine tetra(methylene phosphonic Acid) is a nitrogenous polyphosphonic acid chelator is able to form complexes with various metal ions.

Ethylenediamine tetra(methylene phosphonic Acid) has a strong ability to chelate metal ions, and its complexation constant of copper ion is the largest of all chelating agents, including EDTA.
Ethylenediamine tetra(methylene phosphonic acid) (EDTMPA; CAS 1429-50-1; EC 215-851-5) is a nitrogen-containing organic polyphosphonic acid and chelating agent with strong metal binding, anti-corrosion and scale inhibition properties.

Ethylenediamine tetra(methylene phosphonic acid) (commonly abbreviated EDTMPA or EDTMP) is an organic phosphonic acid with strong chelating and anti-corrosion properties.
Chemically, Ethylenediamine tetra(methylene phosphonic Acid) belongs to the organophosphonic acid family and is the phosphonate analog of ethylenediaminetetraacetic acid (EDTA).

Ethylenediamine tetra(methylene phosphonic Acid)'s molecular structure contains an ethylenediamine core with four methylene phosphonic acid groups attached, making it a polyphosphonic chelating agent useful in many industrial applications where metal ion binding is required.
Ethylenediamine tetra(methylene phosphonic Acid) is usually supplied either as the free acid (EDTMPA) or more commonly in salt forms (e.g., sodium salts) to improve water solubility.

USES and APPLICATIONS of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) is high-pure grade and innocuous reagent.
Ethylenediamine tetra(methylene phosphonic Acid) can be used as detergent of semiconductor chip to prepare integrated circuit in electronics industry, as carrying agent for radioelement for inspection and therapy of disease in medical industry.

The chelating capacity of Ethylenediamine tetra(methylene phosphonic Acid) largely exceed that of EDTA and DTPA, and can replace EDTA for chelating agent at almost any situation.
Ethylenediamine tetra(methylene phosphonic Acid) is widely used across various sectors:

Water Treatment: Ethylenediamine tetra(methylene phosphonic Acid) acts as an antiscalant and corrosion inhibitor, effectively preventing scale formation in industrial systems.
Radiopharmaceuticals: Its chelating properties make Ethylenediamine tetra(methylene phosphonic Acid) suitable for labeling metal ions in cancer therapy.

Agriculture: Ethylenediamine tetra(methylene phosphonic Acid) is utilized as a chelating agent for micronutrients to enhance soil quality and plant growth.
Ethylenediamine tetra(methylene phosphonic Acid) is used in organic synthesis and pharmaceutical industry, dye intermediates, etc.

Ethylenediamine tetra(methylene phosphonic Acid) has a strong ability to chelate metal ions, and the complexing constant with copper ions is the largest among all chelating agents including EDTA.
Ethylenediamine tetra(methylene phosphonic Acid) is a high-purity reagent and non-toxic.

Ethylenediamine tetra(methylene phosphonic Acid) can be used as a cleaning agent for semiconductor chips in the electronic industry to manufacture integrated circuits.
As a carrier of radioactive elements in the pharmaceutical industry, Ethylenediamine tetra(methylene phosphonic Acid) is used to check and treat diseases.

The chelating ability of Ethylenediamine tetra(methylene phosphonic Acid) far exceeds EDTA and DTPA, and EDTMPA can be replaced in almost all places where EDTA is used as chelating agent.;
Ethylenediamine tetra(methylene phosphonic Acid) is used as scale and corrosion inhibitor for steam boilers, scale inhibitor for circulating cooling water, stabilizer for peroxide, metal ion chelating agent for electroplating industry, etc.

Ethylenediamine tetra(methylene phosphonic Acid) or ethylenediamine tetra(methylene phosphonic acid) is a phosphonic acid.
Ethylenediamine tetra(methylene phosphonic Acid) has chelating and anti corrosion properties.
Ethylenediamine tetra(methylene phosphonic Acid) is the phosphonate analog of EDTA.

Ethylenediamine tetra(methylene phosphonic Acid) is classified as a nitrogenous organic polyphosphonic acid.
Ethylenediamine tetra(methylene phosphonic Acid) can be used as a detergent in the semiconductor chip to prepare an integrated circuit, as a carrying agent for radioelement in the medical industry, and as an agent for inspection and therapy.

Ethylenediamine tetra(methylene phosphonic Acid) can be used as detergent in semiconductor chip to prepare integrated circuit, as carrying agent for radioelement in medical industry, and as agent for inspection and therapy.
Ethylenediamine tetra(methylene phosphonic Acid) is used in detergents as an incrustation control agent and for the stabilization of bleach components.

Ethylenediamine tetra(methylene phosphonic Acid) is also used in oilfield formulations and as a peroxide bleach stabilization agent in textile auxiliaries.
Ethylenediamine tetra(methylene phosphonic Acid) has a high dispersing power for ceramic slurries and retards setting in building materials.

Ethylenediamine tetra(methylene phosphonic Acid) is a methylene phosphonic acid Cathodic corrosion inhibitor, which has more prominent cathodic protection effect than inorganic polyphosphate, and the corrosion inhibition rate is about 7 times higher.
At 200 deg C has better scale inhibition.

The combination of Ethylenediamine tetra(methylene phosphonic Acid) and polymaleic anhydride can effectively reduce the scaling rate.
Ethylenediamine tetra(methylene phosphonic Acid) is used to do Scale Inhibitor.
Ethylenediamine tetra(methylene phosphonic Acid) is used alone concentration is 10 mg/L,EDTMP do inhibitor used alone concentration is greater than lOOmg/L,EDTMP and low relative molecular mass scale inhibitor used in combination concentration is less than 5mg/L.

The combination of Ethylenediamine tetra(methylene phosphonic Acid) and sodium gluconate can clean and treat the metal surface and remove the grease on the metal surface.
In addition, high-purity Ethylenediamine tetra(methylene phosphonic Acid) can be used as a cleaning agent for semiconductor chips in the electronics industry;

In the pharmaceutical industry, Ethylenediamine tetra(methylene phosphonic Acid) is used as a carrier of radioactive elements for the detection and treatment of diseases;

Ethylenediamine tetra(methylene phosphonic Acid) has a strong ability to chelate metal ions, and the complexation constant with copper ions is the largest of all chelating agents, including ethylenediaminetetraacetic acid, and can be replaced by EDTMP in almost all places where ethylenediaminetetraacetic acid is used as a chelating agent.

Ethylenediamine tetra(methylene phosphonic Acid) is used metal ion chelating agent for electroplating industry.
Ethylenediamine tetra(methylene phosphonic Acid) is used in detergents as an incrustation control agent and for the stabilization of bleach components.

Ethylenediamine tetra(methylene phosphonic Acid) is typically a white to off-white solid and is soluble in water, making it useful in various applications, particularly in the fields of water treatment and as a chelating agent.
Ethylenediamine tetra(methylene phosphonic Acid) exhibits strong chelating properties, allowing it to effectively bind metal ions, which can help in preventing scale formation and corrosion in industrial systems.

Additionally, Ethylenediamine tetra(methylene phosphonic Acid) has applications in agriculture as a fertilizer additive and in the pharmaceutical industry due to its potential in drug formulation.
The presence of multiple phosphonic acid groups contributes to its high stability and effectiveness in complexing with divalent and trivalent metal ions.

Ethylenediamine tetra(methylene phosphonic Acid), often referred to as EDTMP, is a chelating agent with a high affinity for metal cations, which is extensively used in various research applications.
In the field of water treatment, Ethylenediamine tetra(methylene phosphonic Acid) is studied for its ability to inhibit the formation of scale by sequestering metal ions.

Its effectiveness in controlling mineral deposition makes Ethylenediamine tetra(methylene phosphonic Acid) a subject of interest in industrial applications where water hardness is an issue.
In materials science, Ethylenediamine tetra(methylene phosphonic Acid) is investigated for its role as a corrosion inhibitor, particularly in systems where it can form stable complexes with metal ions, thus preventing oxidative damage to metal surfaces.

Furthermore, research in geochemistry utilizes Ethylenediamine tetra(methylene phosphonic Acid) to understand the mobility and distribution of trace metals in natural waters, as it can strongly influence the speciation of metals in aquatic environments.
Additionally, its properties are exploited in the study of nuclear waste management, where Ethylenediamine tetra(methylene phosphonic Acid) may be used to immobilize radioactive metal ions, reducing their environmental impact.

As a phosphonate, Ethylenediamine tetra(methylene phosphonic Acid) disrupts normal crystal growth of scale precursors (like calcium carbonate and sulfate), helping prevent scale buildup on heat exchange and boiler surfaces.
Ethylenediamine tetra(methylene phosphonic acid) and its salts are used widely in industrial, water treatment, and specialized technical applications.

Chelating Agent: Ethylenediamine tetra(methylene phosphonic Acid) is employed to sequester (bind) metal ions in aqueous systems where preventing precipitation and scaling is needed, such as in textiles, dyeing, electroplating, and pulp/paper operations.
Industrial and Technical Uses of Ethylenediamine tetra(methylene phosphonic Acid): Detergents and cleaning formulations: Ethylenediamine tetra(methylene phosphonic Acid) helps stabilize the formulation by binding metals.

Electronics industry: Ethylenediamine tetra(methylene phosphonic Acid) is used in cleaning solutions for semiconductor chips due to its chelating properties.
Radiopharmaceutical preparation uses of Ethylenediamine tetra(methylene phosphonic Acid): In specialized formulations (e.g., complexes with radiolanthanides for bone-palliation therapeutics such as Lexidronam, a derivative).

Ethylenediamine tetra(methylene phosphonic Acid) is used extensively in industrial water treatment, electroplating, detergents, semiconductor cleaning, and can serve as a precursor for specialized radiopharmaceuticals.
In its free acid form, Ethylenediamine tetra(methylene phosphonic Acid) is a white crystalline powder with limited water solubility; sodium salt forms are often used to enhance water miscibility.

-Water Treatment uses of Ethylenediamine tetra(methylene phosphonic Acid):
Ethylenediamine tetra(methylene phosphonic Acid) is used as a scale inhibitor and corrosion inhibitor in circulating cooling water systems, boiler water systems, and industrial water treatment, often as a sodium salt form for better water solubility.
Ethylenediamine tetra(methylene phosphonic Acid) offers superior performance to inorganic polyphosphates in preventing scale and corrosion.

FEATURES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) is a broad spectrum scale inhibitor.
Particularly effective against calcium sulphate and barium sulphate.
Ethylenediamine tetra(methylene phosphonic Acid) is a powerful complexing agent with a high calcium tolerance.
Ethylenediamine tetra(methylene phosphonic Acid) is an excellent chelant and also has good chemical and thermal stability.

Ethylenediamine tetra(methylene phosphonic Acid) has strong metal ion chelating capacity, The complex constant with Cu is the largest in all chelating agents including EDTA.
Ethylenediamine tetra(methylene phosphonic Acid) can replace EDTA for chelating agent at almost any situation.

PROPERTIES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) is white crystal powder at room temperature, with melting point 215-217℃, easy dissolved in ammonia, but hard to be dissolved in water: the solubility is less that 5% at room temperature.
Ethylenediamine tetra(methylene phosphonic Acid) has a strong ability to chelate metal ions, and its complexation constant of copper ion is the largest of all chelating agents, including EDTA.

PROPERTIES AND APPLICATIONS of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) is normally delivered as its sodium salt, which exhibits good solubility in water.
Ethylenediamine tetra(methylene phosphonic Acid) is used in water treatment as an antiscaling and anti corrosion agent, the corrosion inhibition of EDTMP is 3–5 times better than that of inorganic polyphosphate.

Ethylenediamine tetra(methylene phosphonic Acid) can degrade to Aminomethylphosphonic acid.
Ethylenediamine tetra(methylene phosphonic Acid) shows excellent scale inhibition ability under temperature 200 °C.
Ethylenediamine tetra(methylene phosphonic Acid) functions by chelating with many metal ions.

CHEMICAL REACTIONS of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Due to Ethylenediamine tetra(methylene phosphonic Acid)'s unique structure, featuring multiple phosphonic acid groups.
These groups enable Ethylenediamine tetra(methylene phosphonic Acid) to chelate metal ions effectively, forming stable complexes that are crucial in applications like water treatment.
Ethylenediamine tetra(methylene phosphonic Acid) can degrade into aminomethylphosphonic acid under certain conditions, demonstrating its reactivity and potential environmental impact.

PROPERTIES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) is white crystal powder at room temperature, with a melting point of 215~217℃.
Ethylenediamine tetra(methylene phosphonic Acid) is hard to be dissolved in water.
The solubility of Ethylenediamine tetra(methylene phosphonic Acid) is less than 5% at room temperature and is easily dissolved in ammonia.
Ethylenediamine tetra(methylene phosphonic Acid) acid acid has a strong metal ion chelating capacity, whose chelating constant with cuprum ion is larger than that of EDTA.

SALT FORMS of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Due to poor water solubility of the free acid, sodium salts (e.g., pentasodium or octasodium EDTMP) are commonly used in formulations where aqueous solubility and dispersion are required, such as in industrial water treatment and corrosion control.

PHYSICAL AND CHEMICAL PROPERTIES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Pure white crystals.
Industrial products are light yellow.
Goods are generally yellow-brown transparent viscous liquid.
The relative density of 1.3~1.4.
Dry product decomposition temperature of 223~228.
Good chemical stability.

FUNCTIONAL CHARACTERISTICS of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) exhibits excellent metal ion chelation due to the presence of multiple phosphonic acid groups, which bind strongly to metal ions such as Ca²⁺, Mg²⁺, Fe³⁺, and Cu²⁺.
This makes Ethylenediamine tetra(methylene phosphonic Acid) effective where strong chelation is needed for scale control, dispersion, and corrosion inhibition.
Ethylenediamine tetra(methylene phosphonic Acid)'s metal-binding (chelating) capability is often greater than that of EDTA in similar conditions.

DECOMPOSITION MECHANISM of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
The thermal decomposition of iron complexes involving Ethylenediamine tetra(methylene phosphonic Acid) has been studied extensively.
Research indicates that the P-C bonds in Ethylenediamine tetra(methylene phosphonic Acid) complexes are more prone to breakage compared to C-C bonds in similar compounds like iron ethylenediaminetetraacetic acid (EDTA) complexes.
This difference arises from the structural characteristics of the phosphonic acid groups, leading to distinct decomposition pathways.

BIOLOGICAL ACTIVITY of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) exhibits significant biological activity, particularly in the field of radiopharmaceuticals.
Ethylenediamine tetra(methylene phosphonic Acid) is utilized in the formulation of radiolabeled compounds for diagnostic imaging and cancer treatment.

For instance, Samarium-153 lexidronam, an anti-cancer drug derived from Ethylenediamine tetra(methylene phosphonic Acid), showcases its therapeutic potential.
Ethylenediamine tetra(methylene phosphonic Acid)'s ability to chelate with metal ions enhances the stability and efficacy of these radiopharmaceuticals.

MANUFACTURING INFO of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Phosphonic acid, P,P',P'',P'''-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-: ACTIVE

SYNTHESIS METHODS of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
The synthesis of Ethylenediamine tetra(methylene phosphonic Acid) involves a modified Mannich-type reaction using phosphorous acid, ethylenediamine, and formaldehyde in the presence of hydrochloric acid.
The process includes:
Mixing phosphorous acid and ethylenediamine with water and hydrochloric acid.

Refluxing the mixture for two hours.
Adding formaldehyde dropwise and continuing reflux for an additional four hours.
Cooling the solution and removing the solvent under reduced pressure.

Precipitating the product with ethanol and filtering it out.
Characterization techniques such as Nuclear Magnetic Resonance (NMR) spectroscopy are employed to confirm the structure of the synthesized compound.

INTERACTION STUDIES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Research has focused on the interaction of Ethylenediamine tetra(methylene phosphonic Acid) with various metal ions, revealing that it forms stable complexes that enhance solubility and bioavailability.
Studies indicate that Ethylenediamine tetra(methylene phosphonic Acid) interacts favorably with ions such as samarium and lutetium, which are critical in medical applications.
Additionally, photodegradation studies have shown that EDTMP can undergo significant changes when exposed to UV light, impacting its stability and efficacy in environmental contexts.

FEATURES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) is a broad spectrum scale inhibitor that is particularly effective against calcium sulphate and barium sulphate.
Ethylenediamine tetra(methylene phosphonic Acid) is a powerful complexing agent with a high calcium tolerance.
Ethylenediamine tetra(methylene phosphonic Acid) is an excellent chelant and also has good chemical and thermal stability.

SYNTHESIS of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) is one of the most widely used ligands which forms stable complexes with various radionuclides all of which have shown high bone affinity and other favorable pharmacological characteristics in biodistribution studies.
The Ethylenediamine tetra(methylene phosphonic Acid) is very important precursor in the preparation of radiopharmaceutical kits which is used in the applications for bone diagnosis and therapy was synthesized in one step with Mannich type reaction.
The obtained product was fully characterized by Ethylenediamine tetra(methylene phosphonic Acid)'s multi-nuclear NMR and IR spectroscopy.
The purity of Ethylenediamine tetra(methylene phosphonic Acid) was confirmed by HPLC.

CLASSIFICATION of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
There are many types of scale and corrosion inhibitors, usually the compounding of some compounds with special structures, and the types should be selected according to factors such as metal surface conditions, corrosion medium composition and operation conditions.
Ethylenediamine tetra(methylene phosphonic Acid) is commonly used scale inhibitors in water treatment include inorganic polyphosphate, organic phosphonic acid, phosphonic acid, organic phosphonic acid, polycarboxylic acid, etc.

There are many types of scale and corrosion inhibitors, and the main products with both corrosion and scale inhibition functions are:
Organic phosphorus scale and corrosion inhibitors: such as ATMP, HEDP, DTPMPA, EDTMPS, HPAA, etc.;

In addition, a small amount of polymer also contains certain scale and corrosion inhibition functions, such as phosphonyl carboxylic acid copolymer, green scale and corrosion inhibitor PESA, PASP, etc.
Scale and corrosion inhibitors are mainly used in industrial circulating water systems such as power plants, steel plants, fertilizer plants, oil field water injection systems, etc.

General end users use a single agent as a scale and corrosion inhibitor is not much, according to the system situation to set the scheme, add a special corrosion and scale inhibitor.
In addition, there are many special corrosion inhibitors, such as MBT (copper corrosion inhibitor), BTA (benzotriazole), TTA (methyl benzotriazole), and hydrochloric acid pickling corrosion inhibitors.

NATURE of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Ethylenediamine tetra(methylene phosphonic Acid) is a white crystalline powder at room temperature.
The melting point of Ethylenediamine tetra(methylene phosphonic Acid) is 215~217 deg C, the relative density of 1.3~1.4.
Decomposition temperature of Ethylenediamine tetra(methylene phosphonic Acid) is 223~228.

Ethylenediamine tetra(methylene phosphonic Acid) is slightly soluble in water, at room temperature solubility of less than 5%, soluble in ammonia.
Chemical stability and thermal stability of Ethylenediamine tetra(methylene phosphonic Acid) is good.
Industrial products are light yellow.

PREPARATION METHOD of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
using ethylene glycol as an intermediate medium, ethylene glycol phosphonate chloride is generated by the reaction of ethylene glycol with phosphorus trichloride, and then reacted with ethylenediamine to obtain phosphorous acid, and then the reaction of phosphorous acid with formaldehyde to obtain ethylenediamine tetramethylene phosphonic acid.
Alternatively, formaldehyde is nucleophilic added with ethylenediamine to form hydroxymethylamine, which is then esterified with the hydrolysis product of pcl3.

PRODUCTION METHOD of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
there are three synthesis methods.
Formaldehyde and ethylenediamine undergo nucleophilic addition to generate hydroxymethylamine, which is then esterified with the hydrolysate of PCl3.

Using ethylene glycol as the intermediate medium, ethylene glycol reacts with carbon dichloride to form phosphate chloride, and then reacts with ethylenediamine and formaldehyde to form Ethylenediamine tetra(methylene phosphonic Acid).

EDTA,PCl3 synthesis.
The first two methods have few by-products, high yield and good product purity.
But the cost is high and the raw materials are more expensive.
At present, the country is still dominated by (1) law.

First, add stoichiometric ethylenediamine to the reaction kettle and add appropriate amount of water to dissolve.
Stir well.
Then add phosphorus trichloride dropwise under cooling.

The reaction temperature should be 40~60 ℃.
After dropping, the temperature is raised to 60 ℃, and formaldehyde aqueous solution is added dropwise.
After dropping, the temperature was raised to 100~120 ℃ and the reaction was about 5 hours.

Cool and blow out the residual hydrogen chloride with air.
Add sodium phosphate aqueous solution to adjust the pH value to 9.5~10.5.
The discharge is the finished product.

PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
Chemical formula: C6H20N2O12P4
Molar mass: 436.13 g/mol
Appearance: solid
Solubility in water: limited
Molecular Weight: 436.12 g/mol
XLogP3-AA: -11.2
Hydrogen Bond Donor Count: 8
Hydrogen Bond Acceptor Count: 14
Rotatable Bond Count: 11
Exact Mass: 435.99667207 Da
Monoisotopic Mass: 435.99667207 Da

Topological Polar Surface Area: 237 Å²
Heavy Atom Count: 24
Formal Charge: 0
Complexity: 486
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
Molecular Formula / Molecular Weight: C6H20N2O12P4 = 436.12
Physical State (20 deg.C): Solid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN: 1429-50-1
Reaxys Registry Number: 1810320
PubChem Substance ID: 87569651
SDBS (AIST Spectral DB): 18830
MDL Number: MFCD00058893
Preferred (IUPAC) Name: Ethylenediamine tetra(methylene phosphonic acid)
Other Names (Synonyms): EDTMP, EDTMPA, Ethylene-1,2-diylbis[nitrilobis(methylene)]tetraphosphonic acid, N,N,N′,N′-tetrakis(phosphonomethyl)ethylenediamine, Ethylenediaminetetra(methylenephosphonic acid)

Molecular Formula: C6H20N2O12P4
Molecular Weight: 436.12 g/mol
CAS Number: 1429-50-1
EC / EINECS Number: 215-851-5
Appearance: White to nearly white crystalline powder
Molecular Formula: C6H20N2O12P4
Molecular Weight: 436.12 g/mol
Melting Point: 215–217 °C

Solubility: Limited solubility in water in the free acid form (typically <5% at room temperature); more soluble when present as sodium salts
Solubility in Ammonia: Soluble
Physical State: Solid at room temperature
Chelating Ability: Strong; higher metal ion chelation constant than EDTA for some ions such as copper
pH: Aqueous solutions of the acid are acidic; salt forms can exhibit neutral to slightly alkaline pH
Stability: Chemically stable under normal storage conditions
Appearance: White crystal powder
Active acid (as EDTMPA)%: 96.0 min
Total phosphonic acid(as PO43-)%: 82.0 min

Chloride (Cl-) %: 0.1 max
Moisture %: 2.0 max
Fe, mg/L: 5.0 max
pH(1% water solution): 2.0 max
CAS: 1429-50-1
EINECS: 215-851-5
InChI: InChI=1/C6H20N2O12P4/c9-21(10,11)3-7(4-22(12,13)14)1-2-8(5-23(15,16)17)6-24(18,19)20/h1-6H2,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20)
InChIKey: NFDRPXJGHKJRLJ-UHFFFAOYSA-N
Molecular Formula: C6H20N2O12P4

Molar Mass: 436.12 g/mol
Density: 1.993±0.06 g/cm3 (Predicted)
Melting Point: 247 °C
Boiling Point: 878.7±75.0 °C (Predicted)
Flash Point: 485.2 °C
Water Solubility: 19.6 g/L at 20 °C
Solubility: Aqueous Base (Slightly)
Vapor Pressure: 0 Pa at 25 °C
Appearance: Crystallization

Color: White
pKa: 0.13±0.10 (Predicted)
Storage Condition: Hygroscopic, -20°C Freezer, Under inert atmosphere
Refractive Index: 1.622
MDL: MFCD00058893
Molecular Weight: 436.12400
Exact Mass: 436.12
EC Number: 263-254-3
UNII: V4CP8RSX7V
DSSTox ID: DTXSID3061689
HScode: 2931900090

PSA: 275.84000
XLogP3: -1.86880
Density: 1.993 g/cm3
Melting Point: 247 °C
Boiling Point: 878.7 °C at 760 mmHg
Flash Point: 485.2 °C
Refractive Index: 1.622
Vapor Pressure: 2.43E-34 mmHg at 25 °C
Molecular Weight: 436.12
XLogP3: -11.2
Hydrogen Bond Donor Count: 8
Hydrogen Bond Acceptor Count: 14
Rotatable Bond Count: 11

Exact Mass: 435.99667207
Monoisotopic Mass: 435.99667207
Topological Polar Surface Area: 237
Heavy Atom Count: 24
Complexity: 486
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: White crystal powder
Active acid, %: 96.0 Min.
Total phosphonic acid (as PO43-), %: 82.0 Min.
Moisture, %: 2.0 Max.
Fe, mg/L: 5.0 Max.
Chloride (Cl–), %: 0.1 Max.
pH (1% solution): 2.0 Max.

FIRST AID MEASURES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available