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EC / List no.: 206-076-3
CAS no.: 299-29-6
Mol. formula: C12H22FeO14
Iron(II) gluconate, or ferrous gluconate, is a black compound often used as an iron supplement.
Ferrous gluconate is the iron(II) salt of gluconic acid.
Uses:
Medical
Main article: Iron supplement
Ferrous gluconate is effectively used in the treatment of hypochromic anemia.
The use of this compound compared with other iron preparations results in satisfactory reticulocyte responses, a high percentage utilization of iron, and daily increase in hemoglobin that a normal level occurs in a reasonably short time.
Food additive
Ferrous gluconate is also used as a food additive when processing black olives.
Ferrous gluconate is represented by the food labeling E number E579 in Europe.
Ferrous gluconate imparts a uniform jet black color to the olives.
What is ferrous gluconate?
Ferrous gluconate is a type of iron. You normally get iron from the foods you eat.
In your body, iron becomes a part of your hemoglobin (HEEM o glo bin) and myoglobin (MY o glo bin).
Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen.
Ferrous gluconate is used to treat or prevent iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).
Ferrous gluconate may also be used for purposes not listed in this medication guide.
This medication is an iron supplement used to treat or prevent low blood levels of iron (such as those caused by anemia or pregnancy). Iron is an important mineral that the body needs to produce red blood cells and keep you in good health.
How to use Ferrous Gluconate
Follow all directions on the product package, or take as directed by your doctor.
Do not take more than the recommended dosage. If you have any questions, ask your doctor or pharmacist.
Iron is best absorbed on an empty stomach (usually if taken 1 hour before or 2 hours after meals).
If stomach upset occurs, you may take this medication with food.
See the instructions below for the liquid drops for infants/children.
Avoid taking antacids, dairy products, tea, or coffee within 2 hours before or after this medication because they will decrease its effectiveness.
Take tablets or capsules with a full glass of water (8 ounces or 240 milliliters) unless otherwise directed by your doctor. Do not lie down for at least 10 minutes after taking your tablet or capsule dose.
Swallow extended-release capsules whole.
Do not crush or chew extended-release capsules or tablets.
Doing so can release all of the drug at once, increasing the risk of side effects.
Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so.
Swallow the whole or split tablet without crushing or chewing.
If you are taking chewable tablets, chew the medication thoroughly, then swallow.
If you are taking a liquid suspension form of this medication, shake the bottle well before each dose.
If you are taking the liquid form for adults, carefully measure the dose using a special measuring device/spoon.
Do not use a household spoon because you may not get the correct dose.
Mix the dose in a glass of water or juice, and drink the mixture through a straw to prevent staining the teeth.
If you are giving the liquid drops to an infant or child, use the dropper provided to carefully measure the dose.
The dose may be placed directly into the mouth (towards the back of the tongue) or it may be mixed in formula (not milk), fruit juice, cereal, or other food as directed to increase your child's acceptance.
Ferrous gluconate is best to give this medication right after a meal.
What is ferrous gluconate?
Ferrous gluconate is a type of iron. You normally get iron from the foods you eat.
In your body, iron becomes a part of your hemoglobin (HEEM o glo bin) and myoglobin (MY o glo bin).
Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen.
Ferrous gluconate is used to treat or prevent iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).
Ferrous gluconate may also be used for purposes not listed in this medication guide.
Ferrous Gluconate is a form of mineral iron for oral administration, Ferrous Gluconate is absorbed in the stomach and small intestine and combines with apoferritin to form ferritin, which is stored in the liver, spleen, red bone marrow, and intestinal mucosa.
Important in transport of oxygen by hemoglobin to the tissues, iron is also found in myoglobin, transferrin, and ferritin, and is as a component of many enzymes such as catalase, peroxidase, and cytochromes. (NCI04)
Ferrous gluconate is a L-alpha-D-Hepp-(1->7)-L-alpha-D-Hepp-(1->3)-L-alpha-D-Hepp-(1->5)-alpha-Kdo.
Chemical Properties
light grey solid
Uses:
Iron Suppliment in Pharmaceutical Formulations etc.
Ferrous Gluconate is a nutrient and dietary supplement that is a source of iron and a coloring adjunct.
Ferrous gluconate is a yellowish gray to pale greenish yellow powder or granules with a burnt sugar odor. it has a solubility of 1 g in approximately 10 ml of water with slight heating.
Ferrous gluconate is used by the pharmaceutical industry as an iron supplement in vitamin pills.
Ferrous gluconate is used by olive growers to darken the olives to a uniform black color.
Ferrous gluconate can function as an iron fortifier in corn and soy products, breakfast cereals, beverages, and dietary foods.
About Ferrous gluconate
Helpful information
Ferrous gluconate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum.
Ferrous gluconate is used at industrial sites and in manufacturing.
Consumer Uses
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
ECHA has no public registered data on the routes by which Ferrous gluconate is most likely to be released to the environment.
Article service life
ECHA has no public registered data on the routes by which Ferrous gluconate is most likely to be released to the environment.
ECHA has no public registered data indicating whether or into which articles the substance might have been processed.
Widespread uses by professional workers
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
ECHA has no public registered data on the types of manufacture using Ferrous gluconate.
ECHA has no public registered data on the routes by which Ferrous gluconate is most likely to be released to the environment.
Formulation or re-packing
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
ECHA has no public registered data on the routes by which Ferrous gluconate is most likely to be released to the environment.
Uses at industrial sites
Ferrous gluconate is used in the following products: pH regulators and water treatment products.
Ferrous gluconate is used in the following areas: mining.
Ferrous gluconate is used for the manufacture of: mineral products (e.g. plasters, cement).
Release to the environment of Ferrous gluconate can occur from industrial use: in processing aids at industrial sites.
Manufacture
Release to the environment of Ferrous gluconate can occur from industrial use: manufacturing of the substance.
IUPAC NAMES:
D-Gluconic acid, Iron (2+) Salt (2:1)
digluconate de fer1.2. Utilisations identifiées pertinentes de la substance ou du mélange et utilisations déconseillées
Ferrous glcuonate
Iron digluconate
iron digluconate
iron(2+) bis(2,3,4,5,6-pentahydroxyhexanoate)
iron(2+) bis(2,3,4,5,6-pentahydroxyhexanoate) (non-preferred name)
Iron; (2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanoic acid
iron; (2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanoic acid
lambda2-iron(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate)
pentahydroxyhexanoic acid
SYNONYMS:
Ferrous gluconate dihydrate
FERROUS GLUCONATE
22830-45-1
UNII-U1B11I423Z
D-Gluconic acid, iron(II) salt, dihydrate
Iron(II) D-gluconate dihydrate
6047-12-7
U1B11I423Z
Fergon
Ferrous gluconate (USP)
Ferrous gluconate [USP]
iron(2+);(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate;dihydrate
CCRIS 7332
MFCD00150872
Enterued (TN)
Gluconic acid, iron(II) salt, hydrate (2:1:2)
Ferrous gluconate usp
Iron(II) gluconate dihydrate
D-Gluconic acid, iron complex
Gluconic acid iron (II) salt
CHEBI:31608
DTXSID601018448
XAA83045
AKOS015896165
Gluconic acid, iron(2+) salt, dihydrate
Iron, bis(D-gluconato-O1,O2)-, dihydrate
D02394
A832742
J-014873
Q27290556
ferrous (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate dihydrate
irox(gador)
nionate
ray-gluciron
iron digluconate
Ferrous Gluconate NF, Powder
Ferrous Gluconate USP/FCC, Granular
Ferrous Gluconate(CIQ)
Ferrous Gluconate, Granular
Ferrous Gluconate, Powder
Iron(II) gluconate (non-medicinal)
IRON (II) GLUCONATE
IRON GLUCONATE
biofergate
bis(d-gluconato-o1,o2)-iro
cerevon
entron
fenton
feravol
fergon
fergonpreparations
ferlucon
ferox
ferrin55
ferro-agepha
ferroglyconicum
ferronicum
ferrose
ferrumpolon
glucoferron
gluco-ferrum
glucomax
gluconicacid,iron(2+)salt(2:1)
gluconicacidironsalt
gluferate
iromin
iromon(gador)
iron(2+)salt(2:1),d-gluconicaci
Iron,bis(D-gluconato-O1,O2)-
irox
Iron, bis(D-gluconato-.kappa.O1,.kappa.O2)-
GLUCONICACIDFERROUSSALT
Iromon
Ferrous gluconate
Iron(2+) bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate]
Iron(II) D-gluconate
D-g luconic acid iron(II) salt
Ferrous gluconate CRS
Ferrous gluconate USP/EP/BP
Food Grade Powder Ferrous Gluconate?299-29-6
