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GLUCOPON 650 EC

Glucopon 650 EC is a surfactant and cleansing agent used in cosmetics. 
Glucopon 650 EC is a glycoside produced from glucose and lauryl alcohol. 
Glucopon 650 EC and Octyl glucoside are similar products used in cosmetics.

CAS Number: 110615-47-9
Molecular Formula: C18H36O6
Molecular Weight: 348.47484
EINECS Number: 600-975-8

Synonyms: LAURYL GLUCOSIDE;D-Glucopyranose, oligomeric, C10-16-alkyl glycosides;D-GLUCOPYRANOSE,OLIGOMERIC,C10-C16-ALKYLGLYCOSIDES;(C10-16)alkyl D-glycopyranoside;Glucopyranose, oligometric, C10-16-alkyl glycosides;D-Glucopyranoside, C10-16-alkyl, oligomeric;Alkyl-D-Glucopyranose C10-C16;Alkyl Polyglucoside C08 - C16

Glucopon 650 EC is a commercial alkyl polyglucoside (APG) nonionic surfactant made from plant-derived fatty alcohols and glucose, designed for cleaning, wetting, and emulsifying applications in industrial and consumer formulations.
It belongs to a class of “green surfactants” because it is based on renewable raw materials instead of petroleum chemistry.
Glucopon 650 EC makes it a widely used sustainable surfactant.

Glucopon 650 EC consists of alkyl chains (hydrophobic part) linked to glucose units (hydrophilic part) through glycosidic bonds, forming amphiphilic molecules that reduce surface tension between oil and water phases.
This structure allows it to solubilize and disperse oils in aqueous systems.
Glucopon 650 EC makes it important in interface chemistry.

Glucopon 650 EC is typically characterized by a relatively high degree of polymerization in the sugar head group and a longer alkyl chain distribution, giving it strong detergency and good foaming behavior compared with lighter APG grades.
This influences its cleaning strength and formulation behavior.
Glucopon 650 EC makes it important in surfactant engineering.

Glucopon 650 EC is best described as a biodegradable, nonionic surfactant used to improve cleaning efficiency, wetting ability, and emulsification performance in a wide range of formulations.
Its main value is combining performance with low environmental impact.
Glucopon 650 EC makes it important in modern green chemistry.

Glucopon 650 EC is an aqueous solution that provides excellent dishwashing and detergent performance.
Glucopon 650 EC is part of the alkyl polyglucoside (APG) family, which is structurally unique because it contains no ethoxylate groups, sulfates, or quaternary ammonium structures, making it fundamentally different from many conventional petrochemical surfactants.

This absence of strongly reactive or persistent functional groups contributes to its mildness and biodegradability.
Glucopon 650 EC makes it important in clean-label surfactant chemistry.

The hydrophilic-lipophilic balance (HLB) of Glucopon 650 EC is relatively high, meaning it is more water-loving and therefore better suited for oil-in-water emulsions and strong detergency rather than water-in-oil systems.
This determines its typical use in cleaning and aqueous formulations.
Glucopon 650 EC makes it important in formulation selection.

In solution, APG surfactants like Glucopon 650 EC tend to form structured micelles and sometimes larger aggregated assemblies due to hydrogen bonding between glucose head groups, which can influence viscosity and foam behavior.
This gives it different rheological properties compared to simpler surfactants.
Glucopon 650 EC makes it important in solution structure chemistry.

Glucopon 650 ECs performance is often described as “mild but effective,” meaning it provides good cleaning power while maintaining relatively low irritation potential compared to sulfate-based surfactants such as SLS or SLES.
This balance is why it is widely used in personal care formulations.
Glucopon 650 EC makes it important in dermatologically mild product design.

Glucopon 650 EC can also act as a co-surfactant that enhances the performance of other surfactants by improving micelle formation, lowering surface tension further, and stabilizing emulsions in mixed systems.
This synergistic behavior is widely exploited in industrial formulations.
This makes it important in surfactant synergy systems.

Because it is derived from glucose and fatty alcohols, its production is closely linked to biomass feedstocks such as starch crops and vegetable oils, making it sensitive to agricultural sourcing and sustainability considerations.
Glucopon 650 EC connects it directly to renewable chemical supply chains.
This makes it important in bio-based industrial chemistry.

Its cleaning performance is often enhanced when used in synergistic blends with anionic surfactants, where mixed micelle formation improves grease solubilization and lowers overall surface tension more effectively than either component alone.
This synergy is a key principle in modern detergent formulation.
Glucopon 650 EC makes it important in multi-component surfactant systems.

At the interfacial level, APG surfactants like Glucopon 650 EC can also reduce interfacial tension between immiscible liquids such as oil and water to very low levels, enabling stable emulsions and fine dispersion of hydrophobic phases.
This property is essential in emulsified cleaning systems.
Glucopon 650 EC makes it important in emulsion science.

Because it is derived from renewable raw materials, its production chain is influenced by agricultural feedstock availability, particularly starch crops for glucose and plant oils for fatty alcohols, linking its industrial supply to agricultural economics and sustainability policy.
This makes it sensitive to global biomass markets.
Glucopon 650 EC makes it important in bio-based chemical supply chains.

Boiling point: 301 °C at 101.3 kPa
Density: 1.16 at 20 °C
vapor pressure: 0.008 Pa at 20 °C
refractive index: 1.4450
form: solid
color: slightly yellowish
Odor: mild, sweet, fatty odor
Cosmetics Ingredients Functions: FOAMING; SURFACTANT - FOAM BOOSTING; SKIN CONDITIONING - EMOLLIENT; CLEANSING; SURFACTANT - CLEANSING; SKIN CONDITIONING
Cosmetic Ingredient Review (CIR): Lauryl glucoside (110615-47-9)
InChI: 1S/C18H36O6/c1-2-3-4-5-6-7-8-9-10-11-12-23-18-17(22)16(21)15(20)14(13-19)24-18/h14-22H,2-13H2,1H3/t14-,15-,16+,17-,18/s3
InChIKey: PYIDGJJWBIBVIA-KGFPCJIYNA-N
SMILES: O(CCCCCCCCCCCC)C1OC@HC@@HC@H[C@H]1O |&1:15,18,20,22,r|
LogP: -0.07 at 20 °C

Glucopon 650 EC reduces surface tension by adsorbing at interfaces between water and hydrophobic substances, allowing oils, greases, and particulate soils to be lifted and dispersed into solution more effectively.
This mechanism improves cleaning efficiency even at relatively low concentrations.
Glucopon 650 EC makes it important in detergent performance.

As a nonionic surfactant, it shows excellent compatibility with anionic, amphoteric, and other nonionic surfactants, enabling flexible formulation design without strong ionic incompatibilities.
This allows it to be used in complex detergent systems.
Glucopon 650 EC makes it valuable in formulation chemistry.

In aqueous systems, it forms micelles above its critical micelle concentration, where hydrophobic cores trap oils and organic contaminants while hydrophilic shells maintain dispersion in water.
Glucopon 650 EC is the basis of its emulsifying and cleaning action.
This makes it important in colloidal chemistry.

It also shows good stability in hard water and across a broad pH range, meaning it maintains performance even in the presence of calcium and magnesium ions that often reduce surfactant efficiency.
Glucopon 650 EC makes it suitable for real-world industrial conditions.
Glucopon 650 EC makes it important in robust formulation systems.

Because it is derived from glucose and fatty alcohols, it is readily biodegradable under aerobic conditions, making it favorable for environmentally conscious formulations and regulatory compliance in many regions.
This reduces long-term environmental persistence compared to many synthetic surfactants.
Glucopon 650 EC makes it important in sustainable product design.

Its performance can be tuned by adjusting concentration, temperature, and combination with co-surfactants, allowing manufacturers to optimize foaming, wetting, or emulsification depending on application needs.
Glucopon 650 EC flexibility is a key advantage in industrial formulation design.
This makes it important in applied surfactant technology.

Glucopon 650 EC is part of a broader shift in surfactant chemistry toward sugar-based amphiphiles, where glucose-derived head groups replace petrochemical ethoxylates and sulfates to reduce environmental persistence and improve biological compatibility.
This structural change significantly reduces ecological footprint compared to traditional surfactants.
Glucopon 650 EC makes it important in sustainable surfactant development.

Its molecular behavior in water is strongly influenced by extensive hydrogen bonding between hydroxyl groups on the glucose units, which can create more structured hydration shells around micelles and affect foam texture and stability.
This gives it a distinct sensory and performance profile in formulations.
Glucopon 650 EC makes it important in colloid and interface science.

Unlike many anionic surfactants, Glucopon 650 EC shows minimal sensitivity to water hardness because it does not form insoluble complexes with calcium or magnesium ions, maintaining stable performance in both soft and hard water systems.
This makes it reliable in real-world cleaning conditions.
Glucopon 650 EC makes it important in robust formulation design.

Glucopon 650 EC is classified as a low-to-moderate hazard surfactant, with most risks limited to irritation under concentrated or prolonged exposure conditions rather than systemic toxicity.
Its safety profile is significantly better than many traditional surfactants.
Glucopon 650 EC makes it relatively safe in industrial and consumer use.

Direct exposure to concentrated material may cause eye irritation and mild skin irritation, particularly with repeated contact or insufficient rinsing in occupational environments.
These effects are typically reversible with proper hygiene measures.
Glucopon 650 EC makes basic protective measures important.

Inhalation risk is generally low because of low volatility, but aerosolized forms such as sprays or misted solutions may cause temporary respiratory irritation in poorly ventilated areas.
Ventilation and controlled application reduce this risk effectively.
Glucopon 650 EC makes engineering controls important.

From an environmental perspective, it is considered readily biodegradable under aerobic conditions and less ecotoxic than many conventional surfactants, although high localized concentrations should still be avoided.
Its breakdown products are generally less persistent in ecosystems.
Glucopon 650 EC makes it favorable in environmental risk assessment.

Uses:
Glucopon 650 EC is a mild surfactant.
Glucopon 650 EC creates an excellent and stable foam. 
Glucopon 650 EC is useful in hair care products where it aids hair cleaning abilities without stripping the hair.

Glucopon 650 EC can be used alongside other glucosides to enhance the foam and skin conditioning properties. 
Glucopon 650 EC is very effective when used in ionic formulations to add foam depth and emulsifying properties.
Glucopon 650 EC is very useful for Bath Foams, Shower Gel and Shampoo where you wish to increase the foaming ability of the product without a decrease in the natural formulation.

Glucopon 650 EC is biodegradable.
Glucopon 650 EC is not only used as surfactant in personal care products, but also can be used as raw material for organic synthesis by reacting with maleic anhydride and then sulfonating with sodium sulfite to synthesise AG-SS. 
Glucopon 650 EC is used as cement air-entraining agent to accelerate the hydration reaction, so as to make the distribution of small air holes in the cement slurry uniformly, and thus to greatly improve the compressive strength of the cement slurry.

Glucopon 650 EC is widely used in industrial cleaning products where strong wetting, grease removal, and soil dispersion are required for metal, equipment, and surface cleaning applications.
It improves cleaning efficiency while maintaining relatively low toxicity.
Glucopon 650 EC makes it important in industrial cleaning systems.

In household detergents, it is used in dishwashing liquids, laundry detergents, and all-purpose cleaners to enhance foam stability, grease removal, and overall cleaning performance.
It also contributes to milder formulations compared to harsher surfactants.
This makes it important in consumer cleaning products.

In personal care products, it is used in shampoos, body washes, and facial cleansers where mild cleansing action and good foaming behavior are required without excessive skin irritation.
It is often chosen for “gentle” or eco-labeled formulations.
Glucopon 650 EC makes it useful in cosmetic chemistry.

In agriculture, it is used as a spray adjuvant to improve spreading, wetting, and penetration of pesticide and herbicide formulations on plant surfaces.
This increases the effectiveness of active ingredients.
Glucopon 650 EC makes it important in agrochemical formulations.

In textile processing, it is used to remove oils, waxes, and processing residues from fibers before dyeing and finishing, ensuring more uniform chemical treatment of fabrics.
Glucopon 650 EC improves textile quality and dye consistency.
This makes it important in textile manufacturing.

In coatings and specialty formulations, it is used as an emulsifier and dispersing agent for pigments, oils, and hydrophobic additives to maintain stable, homogeneous mixtures.
Glucopon 650 EC prevents phase separation and improves product stability.
This makes it important in industrial formulation engineering.

Glucopon 650 EC is widely used in industrial degreasers and hard-surface cleaners where strong removal of oils, lubricants, and particulate soils is required without using highly aggressive or toxic solvents.
It improves cleaning efficiency while maintaining environmental compatibility.
Glucopon 650 EC makes it important in industrial cleaning formulations.

In household cleaning products, it is used in multi-purpose cleaners, dishwashing liquids, and laundry detergents where balanced foam, grease removal, and mildness are required simultaneously.
It helps reduce the need for harsher surfactants.
This makes it important in consumer cleaning systems.

In personal care applications, it is used in shampoos, shower gels, and facial cleansers where gentle cleansing and good foam stability are required without excessive skin barrier disruption.
It is often chosen for sensitive-skin or eco-labeled products.
Glucopon 650 EC makes it important in cosmetic formulation science.

In agricultural chemistry, it is used as a spray adjuvant that improves wetting, spreading, and penetration of active ingredients on waxy or hydrophobic plant surfaces.
This enhances pesticide and herbicide effectiveness.
Glucopon 650 EC makes it important in agrochemical delivery systems.

In textile and leather processing, it is used to remove oils, waxes, and processing residues before dyeing or finishing, ensuring more uniform chemical treatment and coloration.
This improves product consistency and quality.
Glucopon 650 EC makes it important in textile finishing chemistry.

In coatings, inks, and dispersions, it is used as a wetting and dispersing agent to stabilize pigments, fillers, and hydrophobic additives in water-based systems.
This prevents clumping and phase separation.
Glucopon 650 EC makes it important in industrial dispersion technology.

Glucopon 650 EC is widely used in high-performance industrial degreasers where removal of heavy oils, lubricants, and hydrophobic contaminants is required without relying on harsh solvents or strongly corrosive chemistry.
It provides effective cleaning with lower environmental impact.
Glucopon 650 EC makes it important in industrial cleaning systems.

Glucopon 650 EC is used in eco-friendly detergents, dishwashing liquids, and multipurpose cleaners designed to combine strong cleaning performance with mild skin compatibility and biodegradability.
It supports the development of environmentally conscious consumer products.
Glucopon 650 EC makes it important in household care chemistry.

Glucopon 650 EC is used in shampoos, body washes, and facial cleansers where gentle foaming, low irritation potential, and good rinsability are required for sensitive skin applications.
Glucopon 650 EC helps maintain skin barrier integrity during cleansing.
This makes it important in cosmetic surfactant systems.

In agriculture, it functions as an adjuvant that enhances pesticide and herbicide coverage by improving wetting and spreading on hydrophobic leaf surfaces, increasing biological efficacy of active ingredients.
This reduces runoff and improves spray efficiency.
This makes it important in agrochemical delivery systems.

In textile and leather industries, it is used for scouring and pre-treatment processes to remove oils, waxes, and processing residues before dyeing or finishing operations.
This ensures uniform dye uptake and fabric quality.
Glucopon 650 EC makes it important in textile processing chemistry.

In coatings, inks, and pigment dispersions, it is used as a stabilizing surfactant that prevents particle aggregation and improves long-term dispersion stability in water-based systems.
This improves product shelf life and visual consistency.
Glucopon 650 EC makes it important in industrial dispersion technology.

Safety Profile:
Glucopon 650 EC is considered quite safe for your skin as it is a very mild surfactant, that poses little or no risk of irritation. 
In fact that is why it is included in skin care products meant to be used for sensitive skin.
A number of agencies such as the Safe Cosmetics Database, GoodGuide database, EcoCert and the Organic Food Federation consider lauryl glucoside as a safe ingredient. 

Glucopon 650 EC is even included in the CIR list of safe ingredients for cosmetics.
Glucopon 650 EC can be used in facial cleansers while 15 to 30% in shampoos and body washes. 

Glucopon 650 EC is generally considered a low-hazard surfactant with favorable environmental and toxicological properties compared to many traditional petrochemical surfactants.
Its main risks are related to irritation rather than systemic toxicity.
Glucopon 650 EC makes it relatively safe in industrial use.

Direct contact with concentrated material may cause mild to moderate eye irritation and possible skin irritation, especially with prolonged or repeated exposure.
Use of gloves and eye protection is recommended during handling.
Glucopon 650 EC makes personal protection important.

Inhalation risk is generally low due to its low volatility, although inhalation of sprays or aerosols may cause temporary respiratory discomfort in poorly ventilated areas.
Proper ventilation reduces exposure risk significantly.
Glucopon 650 EC makes engineering controls useful.

Glucopon 650 EC is considered readily biodegradable and has lower aquatic toxicity compared to many conventional surfactants, although large uncontrolled releases should still be avoided.
Environmental management remains necessary in industrial use.
Glucopon 650 EC makes environmental safety important.

The compound is chemically stable under normal storage conditions but should be protected from extreme temperatures and contamination to maintain product quality and performance consistency.
This ensures reliable formulation behavior.
Glucopon 650 EC makes proper storage important.

Glucopon 650 EC is a modern, bio-based surfactant that combines effective cleaning and emulsifying performance with low toxicity and good biodegradability, making it widely used in environmentally conscious formulations while still requiring standard industrial safety practices.
Its balance of performance and sustainability is its key advantage.
Glucopon 650 EC makes it a leading green surfactant in modern chemistry.

 

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