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CAS NO:1120360-13-5
Glyceryl Ascorbate at a Glance
Made by binding ascorbic acid with hydrating glycerin
Helps visibly fade discoloration by inhibiting transfer of excess melanin
Excellent skin penetration and easier to formulate with than ascorbic acid
Not considered as potent an antioxidant as pure vitamin C (ascorbic acid)
Most effective in a pH between 3–5 and more stable than ascorbic acid
Glyceryl Ascorbate Description
Glyceryl ascorbate is a water-soluble form of vitamin C made by binding ascorbic acid with the humectant glycerin.
Glyceryl Ascorbate is considered more stable and offers formulary flexibility because it isn’t beholden to the same narrow pH range for efficacy compared to pure vitamin C (ascorbic acid).
This form shares many of the same benefits as regular vitamin C, including being an antioxidant, improving skin tone, helping to fade hyperpigmentation and post-breakout marks, and supporting skin’s firmness.
A derivative of glyceryl ascorbate known as 3-O-Laurylglyceryl ascorbate (VC-3LG) has been shown to improve ceramide synthesis in skin which in turn helps strengthen skin’s surface against moisture loss.
VC-3LG is also a formidable antioxidant and can help improve skin’s natural antioxidant defenses.
Interestingly, although glyceryl ascorbate and its derivatives are very good antioxidants, they’re considered less potent than ascorbic acid, which is less stable in the presence of light and air. This is likely due to the molecular changes necessary to create vitamin C derivatives. There’s a trade-off between greater stability and reduced antioxidant potential.
Concentration range of glyceryl ascorbate in skin care is between 1–10%; however, there are no studies showing which percentages are needed for results on discolorations, wrinkles, or skin tone improvement. Instead, some studies imply that the concentrations for such benefits are comparable to pure vitamin C.
Specifications
Appearance White to Almost white powder to crystal
Purity(Neutralization titration) min. 95.0 %
Melting point 156.0 to 161.0 °C
Specific rotation [a]20/D +52.0 to +57.0 deg(C=1, MeOH)
Properties (reference)
Melting Point 159 °C
Specific Rotation 55° (C=1,MeOH)
Glyceryl ascorbate is a novel, stabilized vitamin C derivative produced by binding vitamin C (ascorbic acid) to glycerin. Has enhanced moisturizing and antioxidant properties when compared with l-ascorbic acid. Can improve appearance of aged and fragile skin. Widely used as add-on ingredient in skin-lightening products to correct hyperpigmentation and age spots. Antioxidant effect can be increased by glyceryl ascorbate with vitamin E.
GLYCERYL ASCORBATE is classified as :
Antioxidant
Humectant
Application/Recommended for
Hair care (Shampoos, Conditioners & Styling)
Skin care (Facial care, Facial cleansing, Body care, Baby care)
bio-based
whitening
Glyceryl ascorbate is a condensate of vitamin C in glycerol.
Glyceryl ascorbate comes as a crystalline, white to yellowish powder.
Glyceryl ascorbate is considered as a more stable form of Vitamin C, which can easily be used into oil-soluble or fat dissolvable form. For more information on vitamin C, refer: Ascorbic acid
TECHNICAL DATA
CAS No: 1120360-13-5
Product Code: VUB36013
MDL No: MFCD28386108
Chemical Formula: C9H14O8
Molecular Weight: 250.2 g/mol
Origin:
Glyceryl ascorbate is made synthetically by attaching glycerin to ascorbic acid (vitamin C).
Overview:
Glyceryl ascorbate is a novel vitamin C derivative that is bound to glycerin.
Glyceryl ascorbate has enhanced moisturizing and antioxidant properties compared to l-ascorbic acid.
Glyceryl ascorbate helps improve the appearance of aging or fragile skin.
Glyceryl ascorbate can also lighten hyperpigmentation and age spots.
Suggested Uses:
Skin toners
Gel serums
Lotions
Creams
Sun care
After sun products
Its functions (INCI)
Antioxidant : Inhibits reactions favored by oxygen, thus avoiding oxidation and rancidity
Humectant : Maintains the water content of a cosmetic in its packaging and on the skin
Glyceryl Ascorbate is a novel, stable form of vitamin C derived from binding ascorbic acid to glycerin.
Glyceryl Ascorbate is a vitamin C derivative that is more stable than powder-derived vitamin C alternatives.
Glyceryl Ascorbate does not discolor over time due to degradation, and since it is a stable product, it will not alter a formulations color or content.
Glyceryl Ascorbate offers the benefits of Vitamin C in a formulation without the instability or degradation of a traditional Vitamin C option.
Key Benefits
Behaves as an anti-oxidant to block UV damage and damage caused by stress, also brightens skin and improves skin regeneration.
Suppresses melanin production for improvement of spots
Conditions and moisturizes skin
Enhances collagen production for improved elasticity
Cosmetic Applications
gel-type formulations such as serums
emulsions such as creams and lotions
mildly acidic formulations
Benefits:
Has enhanced moisturizing and antioxidant properties when compared with l-ascorbic acid
Can improve appearance of aged and fragile skin
Widely used as add-on ingredient in skin-lightening products to correct hyperpigmentation and age spots
Antioxidant effect can be increased by glyceryl ascorbate with vitamin E
Use:
Add to water phase of formula. Usual concentration 1-10%. For external use only. Ideal pH environment 3-5. Do not apply directly to skin. Keep refrigerated
Appearance:
Clear yellowish liquid.
Solubility:
Water-soluble.
Applications:
Skin toners, transparent gel-serums, lotions, creams, sun care & after sun products.
Raw material source:
L-ascorbic acid and glycerin
Manufacture:
Glyceryl ascorbate is made synthetically by attaching glycerin to ascorbic acid (vitamin C).
Animal Testing:
Not animal tested
SYNONYMS:
glyceryl ascorbate
1120360-13-5
(2R)-2-[(1S)-1,2-dihydroxyethyl]-4-(2,3-dihydroxypropoxy)-3-hydroxy-2H-furan-5-one
2-o-glyceryl ascorbic acid
SCHEMBL2069552
VUB36013
MFCD28386108
Glyceryl Ascorbate
Glyceryl Ascorbate >
L-Ascorbic acid, 2-O-(2,3-dihydroxypropyl)-
2-O-(2,3-Dihydroxypropyl)-L-ascorbic Acid
(2R)-2-[(1S)-1,2-Dihydroxyethyl]-4-(2,3-dihydroxypropoxy)-3-hydroxy-2H-furan-5-one
