PRODUCTS

GLYCERYL DIACETATE (DIACETIN)

Glyceryl diacetate (diacetin) is widely applied to the pharmaceutical industry, food emulsifier, cement additive, resin curing agent, solvent, plasticizer, softener and solvent of basic dye.
Glyceryl diacetate (diacetin) is used as a solvent, plasticizer, and softening agent.
Glyceryl diacetate (diacetin) is used in the food industry, it gives dishes a buttery taste.

CAS Number: 25395-31-7 for the mixed isomers (commonly used)
EC Number: 246-941-2
MDL Number: MFCD00008717
Chemical formula: C₇H₁₂O₅ (for the diacetate)
Molar mass: ~ 176.17 g/mol

SYNONYMS:
Glyceryl diacetate, Glycerol diacetate, Glycerine diacetate, Diacetin, Acetin, di-, 1,2,3-Propanetriol, diacetate, 1,2-diacetylglycerol, 1,3-diacetylglycerol, Diacetyl glycerol, Glycerin diacetate, Diacetin; Glycerol diacetate, acetic acid, diglyceride, acetin, 1,2-di-, (1-acetyloxy-3-hydroxypropan-2-yl) acetate, 2,3-diacetin, 2,3-diacetoxypropan-1-ol, diacetyl glycerine, diacetyl glycerol, diacetylglycerol, 1,2-diacetylglycerol, glycerin diacetate, glycerine diacetate, glycerol 1,2-diacetate, glycerol 1,3-di(acetate), glycerol diacetate, glyceryl 1,2-diacetate, glyceryl diacetate, 3-hydroxypropane-1,2-diyl diacetate, 1,2,3-propanetriol 1,2-diacetate, 1,2,3-propanetriol diacetate, 1,2,3-propanetriol, 1,2-diacetate, 1,2,3-propanetriol, diacetate, 1,2,3-Propanetriol, 1,3-diacetate, RefChem:410747, 1,3-Diacetin, 105-70-4, 2-Hydroxypropane-1,3-diyl diacetate, Glyceryl 1,3-diacetate, 1,2,3-Propanetriol,1,3-diacetate, (3-acetyloxy-2-hydroxypropyl) acetate, G45CU3Z186, MFCD00008717, (3-acetoxy-2-hydroxy-propyl) acetate, 3-(acetyloxy)-2-hydroxypropyl acetate, 1,3-Diacetin (Technical grade, ~50%), UNII-G45CU3Z186, 1,3-Diacetoxy-2-propanol, Glycerine 1,3-Diacetate, Glycerol 1,3-Diacetate, 1,2,3-Propanetriol 1,3-Diacetate, EINECS 203-323-7, 1,3-diacetoxy-propan-2-ol, SCHEMBL304203, 1,3-DIACETATE GLYCEROL, Glycerol alpha,alpha'-Diacetate, GLYCERYL-1,3-DIACETATE, DTXSID90146906, MPPODKLDCLFLKT-UHFFFAOYSA-N, 2-Hydroxypropane-1,3-diyldiacetate, AAA10570, 1,3-DIACETIN [USP IMPURITY], AKOS030241027, CS-0256205, G0077, NS00020049, H27316, EN300-1720641, F552750, Q27278722, Diacetin, Carset 555, Carset 533, Acetin, di-, Diacetin FCC, Glycerol Diacetate, GLYCEROLMONO-ANDDIACETATES, 1,2,3-Propanetriol, diacetate, GLYCERIL-ALPHA,ALPHA'-DIACETATE, (2S)-3-hydroxypropane-1,2-diyl diacetate, (2R)-3-hydroxypropane-1,2-diyl diacetate, 2-(Acetyloxy)-1-(hydroxymethyl)ethyl acetate, GLYCERYL DIACETATE, Glycerin diacetate, GLYCEROL DIACETATE, Glycerol 1,3-diacetate, 3-Hydroxypropane-1,2-diyl diacetate, 2-(Acetyloxy)-1-(hydroxymethyl)ethyl acetate, di-aceti, DIACETIN, Carset 555, Carset 533, 1,2,3-Propanetriol, 1,2-diacetate, 2-(Acetyloxy)-1-(hydroxymethyl)ethyl acetate, 1,2-Diacetin, Acetin, 1,2-di-, Acetic acid, diglyceride, (Hydroxymethyl)ethylene acetate, 1,2-Diacetylglycerol, 2,3-Diacetin, 2,3-Diacetoxypropan-1-ol, NSC 2348, glyceryl diacetate, 1,2-diacetin, glycerol diacetate, 1,2,3-propanetriol, diacetate, 3-hydroxypropane-1,2-diyl diacetate, glycerol 1,2-diacetate, 1,2-diacylglycerol, 2,3-diacetin, 1,2-diacetylglycerol, acetin, di, 1,2,3-Propanetriol,diacetate, Acetin,di-, Diacetin, Glycerol diacetate, Glyceryl diacetate, Diacetylglycerol, Glycerine diacetate, Glycerin diacetate, Estol 1583, Estol 1582, Diacetain glycerol, 1300-63-6, 29860-16-0, 1202865-19-7,

Glyceryl diacetate (diacetin) is a colourless, odorless, oily liquid, slightly soluble in water, easily soluble in alcohol, aether and other organic solvents.
Glyceryl diacetate (diacetin), also known as diacetin, is used as an excipient in pharmaceutical formulations.

Glyceryl diacetate (diacetin), with the CAS number 25395-31-7, is an organic compound that belongs to the class of acetates.
Glyceryl diacetate (diacetin) is a colorless, viscous liquid that is soluble in organic solvents but has limited solubility in water.

Glyceryl diacetate (diacetin) is derived from glycerol and acetic acid, where two hydroxyl groups of glycerol are esterified with acetic acid, resulting in a compound that exhibits both hydrophilic and lipophilic properties.
Additionally, Glyceryl diacetate (diacetin) is recognized for its low toxicity and is often considered safe for use in food and cosmetic applications.

Its chemical structure contributes to its stability and reactivity, making Glyceryl diacetate (diacetin) a versatile ingredient in chemical synthesis and formulation chemistry.
Overall, Glyceryl diacetate (diacetin) serves as an important compound in both industrial and consumer products due to its functional properties.

Glyceryl diacetate (diacetin) is fully miscible in water.
Glyceryl diacetate (diacetin) is hygroscopic.
Glyceryl diacetate (diacetin) is incompatible with oxidizing agents.

Glyceryl diacetate (diacetin) is a food additive with the E number E1517.
Glyceryl diacetate (diacetin) is more generally known as diacetin.
Glyceryl diacetate (diacetin) is the diester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.

Glyceryl diacetate (diacetin) is a colorless, viscous and odorless liquid with a high boiling point.
Glyceryl diacetate (diacetin) is typically a mixture of two isomers, 1,2-Glyceryl diacetate (diacetin) and 1,3-Glyceryl diacetate (diacetin).
Glyceryl diacetate (diacetin), also known as diacetin and numbered E1517, is a colorless, oily liquid with a faint odor.

Glyceryl diacetate (diacetin) is a food ingredient used as a solvent and flavor carrier, as well as a softening agent in food products.
Glyceryl diacetate (diacetin) is obtained by acetylation of glycerol and is valued for its softening properties and its ability to improve the texture and stability of food products.

USES and APPLICATIONS of GLYCERYL DIACETATE (DIACETIN):
Pharmaceuticals: Glyceryl diacetate (diacetin) is used as a solvent and excipient in drug formulations, supporting solubility and stability.
Food Industry: Glyceryl diacetate (diacetin) functions as a food emulsifier and solvent for flavorings, enhancing product texture and stability.
Cosmetics & Personal Care: Glyceryl diacetate (diacetin) acts as an emollient and solvent in lotions and creams, contributing to skin softness and ingredient dissolution.

Industrial Applications: Glyceryl diacetate (diacetin) serves as a plasticizer for polymers and a solvent in various industrial processes.
Solvent Power uses of Glyceryl diacetate (diacetin): High solvency for various organic compounds, crucial for flavor and fragrance applications.
Plasticizing Properties: Glyceryl diacetate (diacetin) enhances flexibility in polymers, making it a key ingredient for plasticizers you can buy.

Emulsifying Capabilities: Glyceryl diacetate (diacetin) stabilizes oil-water mixtures in food products, serving as a critical food emulsifier.
Glyceryl diacetate (diacetin) is widely applied to the pharmaceutical industry, food emulsifier, cement additive, resin curing agent, solvent, plasticizer, softener and solvent of basic dye.

Glyceryl diacetate (diacetin) is used as a solvent, plasticizer, and softening agent.
Glyceryl diacetate (diacetin) is used in the food industry, it gives dishes a buttery taste.
Glyceryl diacetate (diacetin) is also used as a solvent, plasticizer, and softening agent.

Glyceryl diacetate (diacetin) functions as a plasticizer, solubilizer, and stabilizer in various dosage forms, helping to improve the texture and stability of the final product.
This dual nature makes Glyceryl diacetate (diacetin) useful in various applications, including as a solvent, plasticizer, and in the formulation of personal care products.

Glyceryl diacetate (diacetin) is used in chemical manufacturing and other food applications.
Glyceryl diacetate (diacetin) is used in the food industry as a softening agent in chewing gums, as a flavor carrier in beverages and bakery products, and as a texture-enhancing ingredient in a variety of food products.

Glyceryl diacetate (diacetin) is widely used as plasticizer.
Glyceryl diacetate (diacetin) has been used to design and evaluate gliclazide push-pull osmotic pump (PPOP) coated with aqueous colloidal polymer dispersions.

Glyceryl diacetate (diacetin) is widely used as a plasticizer.
Glyceryl diacetate (diacetin) is also used in food, flavors & fragrances and foundry.

ALTERNATIVE PARENTS of GLYCERYL DIACETATE (DIACETIN):
*Dicarboxylic acids and derivatives
*Carboxylic acid esters
*Primary alcohols
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds

SUBSTITUENTS of GLYCERYL DIACETATE (DIACETIN):
*1,2-acyl-sn-glycerol
*Dicarboxylic acid or derivatives
*Carboxylic acid ester
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Primary alcohol
*Organooxygen compound
*Carbonyl group
*Alcohol
*Aliphatic acyclic compound

CHEMICAL AND PHYSICAL PROPERTIES of GLYCERYL DIACETATE (DIACETIN):
Glyceryl diacetate (diacetin) is a colorless, hygroscopic liquid.
Glyceryl diacetate (diacetin) is soluble in water, alcohol, ether, benzene.
Melting point of Glyceryl diacetate (diacetin) is -30°C.
Boiling point of Glyceryl diacetate (diacetin) is 280 °C.
Density of Glyceryl diacetate (diacetin) is 1.1875

WHERE TO BUY GLYCERYL DIACETATE (DIACETIN)?
Glyceryl diacetate (diacetin) is available from raw material suppliers to the food industry and online stores specializing in food additives.
Glyceryl diacetate (diacetin) is usually available in liquid form, making it easy to dispense and mix with other ingredients.

GLYCERYL DIACETATE (DIACETIN)'S FUNCTIONS IN FOODS
As a food additive, Glyceryl diacetate (diacetin) plays a key role in improving the sensory quality and texture of food products.
By enhancing stability, improving flavor and providing texture, Glyceryl diacetate (diacetin) contributes to the production of high-quality foods.

PROPERTIES of GLYCERYL DIACETATE (DIACETIN):
Glyceryl diacetate (diacetin) has good softening properties, which makes it often used in the production of chewing gums and bakery products.
Glyceryl diacetate (diacetin) is also soluble in water and alcohol, allowing it to be used as a solvent for food additives.

PHYSICAL and CHEMICAL PROPERTIES of GLYCERYL DIACETATE (DIACETIN):
CAS Number: 25395-31-7 for the mixed isomers (commonly used)
EC (EINECS) Number: 246-941-2
Chemical formula: C₇H₁₂O₅ (for the diacetate)
Molar mass: ~ 176.17 g/mol
Food-additive number: E1517 (in EU) for glyceryl diacetate used as flavour carrier etc.
IUPAC / structural information: the compound is the diester of glycerol (1,2,3-propanetriol) with acetic acid;
it is typically a mixture of 1,2- and 1,3-diacetate isomers
Appearance: Colourless (to pale) liquid / oily liquid.
Odour: Odourless (or virtually so) in many sources.

Density / Specific gravity: ~1.17-1.19 g/cm³ (some sources list 1.18 at 20 °C)
Boiling point: Around 250-280 °C (at 760 mmHg) or until decomposition.
Melting / freezing point: One source lists ~ –30 °C for one isomer.
Solubility: Soluble in water (or “easily miscible”) and in alcohol.
Vapour pressure: Very low; e.g., <1 mmHg at 20 °C in one SDS.
Partition coefficient (log P): One estimate ~ -0.64 (suggesting somewhat hydrophilic) for an isomer mixture.
Stability / reactivity: Stable under normal conditions; incompatible with strong oxidising agents.
Hygroscopic behaviour reported.
Note: Because it is a diester of glycerol, there are two esters in the molecule; structurally the central glycerol unit has two acetyl substituents and one hydroxyl

CAS Number: 25395-31-7 (for the common mixed isomer)
EC Number: 246-941-2
Chemical Formula: C7H12O5
Molar Mass: 176.168 g/mol
Appearance: Colourless to pale liquid / oily liquid
Odor: Odorless (or very faint)
Density / Specific Gravity: 1.120–1.170 g/cm³ @ 25 °C
Boiling Point: 245–280 °C at 760 mmHg
Melting / Freezing Point: −30 °C

Solubility: Soluble/miscible in water & alcohol
Vapor Pressure: 0.007 mmHg @ 25 °C
Vapor Density: 6.1 (Air = 1)
Log P (estimate): −0.64
Flash Point: >110 °C (TCC)
Assay: 95–100% sum of isomers
Beilstein Number: 1706903
MDL Number: MFCD00008717
XLogP3: −0.30 (est)
Food Additive Number: E1517 (EU)

Typical Uses: Flavor solvent/carrier, softener/plasticiser in food; excipient in pharma/cosmetics
NMR Predictor: Predict (works with Chrome, Edge or Firefox)
Name: (3-acetyloxy-2-hydroxypropyl) acetate
Refractive Index: 1.184–1.187 @ 20 °C
Pounds per Gallon (est.): 9.320–9.736
Food Chemicals Codex Listed: No
Soluble in: Alcohol, Water (6.577 × 10⁵ mg/L @ 25 °C)
CBNumber: CB7280546

Molecular Formula: C7H12O5
Molecular Weight: 176.17
MDL Number: MFCD00008717
MOL File: 25395-31-7.mol
Melting Point: -30 °C
Boiling Point: 280 °C
Density: 1.17 g/mL at 25 °C (lit.)
Vapor Density: 6.1 (vs air)
Vapor Pressure: <1 mm Hg (20 °C)
Refractive Index: n20/D 1.440 (lit.)

Flash Point: >230 °F
Storage Temp.: Inert atmosphere, Room Temperature
Solubility: Alcohol: soluble (lit.)
Form: Liquid
Color: Clear colorless
pH: 5–6 (50 g/L, H2O, 20 °C)
Odor: Very mild alcoholic at 100%
Odor Type: Alcoholic
Biological Source: Synthetic

Water Solubility: Soluble in water, alcohol, ether, benzene
Sensitive: Hygroscopic
Merck: 14,2961
BRN: 1706903
LogP: -0.640
Indirect Additives used in Food Contact Substances: GLYCEROL DIACTATE
FDA 21 CFR: 177.1200
CAS DataBase Reference: 25395-31-7
EWG's Food Scores: 1
FDA UNII: GJ0544W99Q

NIST Chemistry Reference: 1,2,3-Propanetriol, diacetate (25395-31-7)
EPA Substance Registry System: 1,2,3-Propanetriol, diacetate (25395-31-7)
UNSPSC Code: 12352100
NACRES: NA.22
Physical State: Clear, viscous liquid
Color: Colourless
Odor: No data available
Melting Point/Freezing Point: No data available
Initial Boiling Point and Boiling Range: No data available

Flammability (solid, gas): No data available
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: 110 °C - closed cup
Autoignition Temperature: No data available
Decomposition Temperature: No data available
pH: No data available
Viscosity: Kinematic: No data available, Dynamic: No data available
Water Solubility: No data available
Partition Coefficient (n-octanol/water): No data available

Vapor Pressure: < 1 hPa at 20 °C
Density: 1.17 g/cm³ at 25 °C (lit.)
Relative Density: No data available
Relative Vapour Density: No data available
Particle Characteristics: No data available
Explosive Properties: No data available
Oxidizing Properties: No data available
Other Safety Information: Relative vapor density 6.08 (Air = 1.0)
Molecular Weight: 176.17 g/mol

XLogP3-AA: -0.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 6
Exact Mass: 176.06847348 Da
Monoisotopic Mass: 176.06847348 Da
Topological Polar Surface Area: 72.8 Å²
Heavy Atom Count: 12
Formal Charge: 0

Complexity: 147
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical Formula: C7H12O5

Average Molecular Weight: 176.1672
Monoisotopic Molecular Weight: 176.068473494
IUPAC Name: 1-(acetyloxy)-3-hydroxypropan-2-yl acetate
Traditional Name: 1,2,3-propanetriol, diacetate
CAS Registry Number: 101364-64-1
SMILES: CC(=O)OCC(CO)OC(C)=O
InChI Identifier: InChI=1S/C7H12O5/c1-5(9)11-4-7(3-8)12-6(2)10/h7-8H,3-4H2,1-2H3
InChI Key: UXDDRFCJKNROTO-UHFFFAOYSA-N

Linear Formula: (CH3COOCH2)2CHOH
CAS Number: 25395-31-7
Molecular Weight: 176.17
Beilstein: 1706903
EC Number: 246-941-2
UNSPSC Code: 12164502
PubChem Substance ID: 24901997
NACRES: NA.21

Organoleptic: Alcohol
Biological Source: Synthetic
Food Allergen: No known allergens
Exact Mass: 176.068466
HS Code: 2918199090
PSA: 72.83
XLogP3: -0.52650
Appearance: Absorption near colorless, transparent oily liquid
Density: 1.2 ± 0.1 g/cm³

Melting Point: -30 °C
Boiling Point: 259 °C
Flash Point: 90.7 ± 11.7 °C
Refractive Index: 1.444
Water Solubility: Soluble in water, alcohol, ether, benzene
Storage Conditions: Keep container closed when not in use.
Store in a tightly closed container.
Store in a cool, dry, well-ventilated area away from incompatible substances.
Vapor Pressure: <1 mm Hg (20 °C)

CAS: 25395-31-7, 194423-61-5
EINECS: 246-941-2
InChI: InChI=1/C7H12O5/c1-5(9)11-4-7(3-8)12-6(2)10/h7-8H,3-4H2,1-2H3/t7-/m1/s1
Molecular Formula: C7H12O5
Molar Mass: 176.17 g/mol
Density: 1.17 g/mL at 25 °C (lit.)
Melting Point: -30 °C
Boiling Point: 280 °C
Flash Point: >230 °F
Water Solubility: Soluble in water, alcohol, ether, benzene

Solubility: Alcohol: soluble (lit.)
Vapor Pressure: <1 mm Hg (20 °C)
Vapor Density: 6.1 (vs air)
Appearance: Transparent liquid
Color: Clear colorless
Merck: 14,2961
BRN: 1706903
pH: 5-6 (50 g/L, H2O, 20 °C)
Storage Condition: Inert atmosphere, Room Temperature
Sensitive: Hygroscopic
Refractive Index: n20/D 1.440 (lit.)
MDL: MFCD00008717

FIRST AID MEASURES of GLYCERYL DIACETATE (DIACETIN):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of GLYCERYL DIACETATE (DIACETIN):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of GLYCERYL DIACETATE (DIACETIN):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of GLYCERYL DIACETATE (DIACETIN):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of GLYCERYL DIACETATE (DIACETIN):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of GLYCERYL DIACETATE (DIACETIN):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available