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GLYCERYL LAURATE

Glyceryl laurate = Monolauroylglycerin = Monolaurin

CAS Number: 27215-38-4 / 142-18-7
EINECS/ELINCS No: 248-337-4 / 205-526-6
COSING REF No: 76230
Chem/IUPAC Name: Lauric acid, monoester with glycerol / 2,3-dihydroxypropyl laurate

Glyceryl laurate is classified as:
-Emollient
-Emulsifying

Properties of Glyceryl Laurate:
Molar mass: 274.401 g/mol     
Melting point: 63 °C
Boiling point: 186 °C / 1mmHg

Description:
Glyceryl laurate is a monoester of glycerin and lauric acid, used for its skin conditioning and emollient, skin softening and soothing properties. 
Glyceryl laureate is also used in personal care products as a surfactant in order to create natural lather and an emulsifier.
Glyceryl laurate acts as a lubricant on the skin’s surface, which gives the skin a soft and smooth appearance. 
Glyceryl laurate also helps to form emulsions by reducing the surface tension of the substances to be emulsified. 
Glyceryl laurate is used in the formulation of hair dyes and colors, shampoos, cleaning products, and skin care and bath products.
Monolaurin is the mono-ester formed from glycerol and lauric acid. 
Glyceryl laurate, also known as monolaurin, is a monoester produced from vegetable-derived glycerin and lauric acid.
Glyceryl laurate is a plant-based viscosity stabilizer. 
Glyceryl laurate is also a skin-conditioning agent.
We use monolaurin to hold our solid stick deodorant formula together.
Glyceryl laurate is glyceryl monoester. 
Glyceryl laurate is made via the direct esterification of glycerol with a fatty acid that often comes from plant oils.
Glyceryl laurate is a glycerin and lauric acid derived multi-functional ingredient.
Glycerol monolaurate works as a co-emulsifier, emollient and anti-microbial agent. 
Glycerol monolaurate also has some thickening and refatting properties in cleansing formulas. 
When compared with standard monoglycerides, glyceryl laurate has multiple positive characteristics.
Monolaurin should be added to a formulation so that it does not receive severe heating for prolonged periods. 
Glyceryl laurate is a chemical derived from lauric acid, a component of both coconut fat and breast milk.
Glyceryl laurate is used in cosmetics and as a food additive.
People can also take glyceryl laurate as a diatery supplement.
Monolaurin has shown antibacterial and antiviral effects when examined in test tubes and culture dishes.

General Characteristics of Glyceryl Laurate:
Glyceryl laurate is a monoester of glycerin and lauric acid (obtained from vegetable oils).
Monolaurin ranks among the so-called monoglycerides due to the composition.
Glyceryl laurate usually occurs in the form of an oily to waxy consistency.
Glyceryl laurate has a white or yellow color.
Glyceryl laurate has, inter alia, emulsifying effects and serves as a surfactant.
Monolaurin helps to smooth and hydrate the skin.

Use of Glyceryl Laurate:
Monolaurin is most commonly used as a surfactant in cosmetics, such as deodorants. 
As a food additive, glycerol monolaurate is also used as an emulsifier or preservative. 
Monolaurin is also taken as a dietary supplement.
Glyceryl monoesters are primarily used in the formulation of creams and lotions, moisturizers, and other skin care products.
Glyceryl monoesters can also be found in permanent waves, deodorants, bath soaps, eye makeup and foundations.

Occurrence of Glyceryl Laurate:
Monolaurin is found in coconut oil and may be similar to other monoglycerides found in human breast milk.
Lauric acid can be ingested in coconut oil. 
The human body converts lauric acid into monolaurin, furthermore, coconut oil, coconut cream, grated coconut.
Glyceryl laurate is present in many personal care products, including deodorant, shampoo, moisturizer, cleansers, exfoliants and other items.
Glyceryl laurate is a unique, multifunctional compound made from lauric acid obtained from sustainable plant sources. 
Monolaurin is not typically found in a single product and offers elegance and utility to personal care and pharmaceutical products.
Lauric acid is mainly found in:
-dietary supplements
-coconut oil
-coconut cream
-fresh coconut
-coconut milk
-human breast milk

Pharmacology of Glyceryl Laurate:
Monolaurin has antibacterial, antiviral, and other antimicrobial effects in vitro, but its clinical usefulness has not been established. 
Monolaurin is currently sold as a dietary supplement and is categorized in the United States by the Food and Drug Administration as generally recognized as safe.
Glyceryl laurate is known to inactivate lipid-coated viruses by binding to the lipid-protein envelope of the virus.
Other studies show that Monolaurin disintegrates the protective viral envelope, killing the virus.
Glyceryl laurate has been studied to inactivate many pathogens including Herpes simplex virus and Chlamydia trachomatis.
Monolaurin also shows promising effects against bacteria (both gram-positive and gram-negative), yeast, fungi, and protozoa. 
Bacteria and other microbes have all been neutralized by monolaurin in scientific studies. 
Monolaurin also shows antibacterial and anti-biofilm properties against Borrelia burgdorferi and Borrelia garinii.

Functions of Glyceryl Laurate:
Emollient: Glyceryl laurate softens and soothes the skin. 
Glyceryl laurate prevents water (moisture) loss from the skin.
Emulsifier: Monolaurin allows water and oils to remain mixed together to form an emulsion.
Surfactant: Glyceryl laurate reduces the surface tension to allow mixtures to be formed evenly.
Glyceryl laurate can be dispersed in water and dissolved in oil. 
Glyceryl laurate acts as a rheology modifier.
Glyceryl laurate improves the consistency of preparations containing anionic surfactants, thanks to the formation of the so-called mixed micelles. 
When monolaurin used in rinse-off preparations (e.g., in hair conditioners), monolaurin will facilitate washing off the preparation from the hair surface. 
Monolaurin facilitates the removal of impurities.
The composition of monolaurin ranks among the so-called monoglycerides.
Monolaurin usually occurs in the form of an oily to waxy consistency and has a white or yellow color.
Glyceryl laurate is a monoester of glycerin and lauric acid (obtained from vegetable oils).
Glycerol monolaurate helps to smooth and hydrate the skin. 
Glycerol monolaurate is an effective component of body lotions, moisturizers, but also soaps or makeup. 
However, glyceryl laurate is often found in the composition of deodorants, for one simple reason. 
Monolaurin has an antibacterial effect and prevents the decomposition of sweat. 
Glycerol monolaurate keeps the skin underarms without an undesirable odor.

Cosmetic Action of Glyceryl Laurate:
Glyceryl laurate is used in skin and hair care products.
Glyceryl laurate creates an occlusive layer (film) on their surface, which prevents excessive evaporation of water from the surface. 
Glycerol monolaurate indirectly moisturizes the skin.
Glyceryl laurate conditions the skin and hair, and the resulting film smoothes the surface of the epidermis and hair. 
Glycerol monolaurate gives shine. 
Glyceryl laurate is used as a re-greasing agent in cleansing preparations. 
Glyceryl laurate is safe for use in cosmetic products. 
In cosmetic products, monolaurin also has softening effects.

Applications of Glyceryl Laurate:
Primary & auxiliary emulsifier for cosmetic emulsions & hand washes.

Benefits of Glyceryl Laurate:
Monolaurin shows antibacterial effects against a range of bacteria such as Staphylococcus aureus (Staph).
There are many antibiotic-resistant bacteria that no longer respond to medications. 
Monolaurin might be helpful, has few side effects, and monolaurin is cost-effective to use.
Monolaurin is reported to inhibit several lipid-coated viruses that affect humans and animals, including:
-cytomegalovirus
-measles
-Herpes simplex-1
-Herpes simplex-2
-HIV
-visna virus
-Epstein-Barr virus
-influenza
-pneumonovirus
Both monolaurin and coconut oil, which contains lauric acid, are possibly best known for their antifungal effects.

Possible Uses of Glyceryl Laurate:
-preventing and treating bacterial, fungal, or viral infections
-treating some skin conditions
-treating some antibiotic-resistant infections, such as Staphylococcus aureus)
-boosting the immune system
Monolaurin also has uses in food production and manufacturing. At present, people use monolaurin in the production of:
-margarine
-pasta
-deodorant
-cosmetics
-detergents
-insecticides

Synonyms: 
1- Monomyristin
Glyceryl monolaurate
1-Glyceryl laurate
1-Monododecanoylglycerol
1-Monolaurin
1-Monolauroyl-rac-glycerol
3-Dodecanoyloxy-1,2-propanediol
Dodecanoic acid alpha-monoglyceride
Dodecanoic acid, 2,3-dihydroxypropyl ester
Glucerol alpha-monolaurate
Glycerin 1-monolaurate
Glycerol 1-laurate
Lauric acid 1-monoglyceride
Lauric acid alpha-monoglyceride
Lauricidin
alpha-Monolaurin; 2,3-Dihydroxypropyl laurate

Forms and Dosage of Glyceryl Laurate:
The richest food source of lauric acid is coconut oil, with certain coconut products consisting of nearly 50 percent lauric acid.
It is likely that the appropriate dose of monolaurin depends on several factors, including:
-age
-health status
-presence of other conditions

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