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GLYCIDOXYPROPYLMETHYLDIETHOXYSILANE

Glycidoxypropylmethyldiethoxysilane is a colorless transparent liquid that can be used as an automotive laminate, furniture laminate or flocking adhesive. 
Glycidoxypropylmethyldiethoxysilane benefits from a silane cross-linked water stable single component system that reduces scrap, improves process efficiency and reduces cross-linker toxicity. 
Glycidoxypropylmethyldiethoxysilane can also be used as an adhesion promoter for waterborne system such as acrylic sealant.

CAS Number: 2897-60-1
Molecular Formula: C11H24O4Si
Molecular Weight: 248.39
EINECS Number: 220-780-8

Synonyms: 2897-60-1, Diethoxy(methyl)(3-(oxiran-2-ylmethoxy)propyl)silane, 3-(Methyldiethoxysilyl)propyl glycidyl ether, DTXSID2044638, (gamma-Glycidoxypropyl)methyldiethoxysilane, Diethoxy(3-(glycidyloxy)propyl)methyl silane, 3-GPMDES, EINECS 220-780-8, H04254P08T, NSC 252159, NSC-252159, Silane, diethoxymethyl(3-(oxiranylmethoxy)propyl)-, gamma-glycidoxypropylmethyldiethoxysilane, Silane, (3-(2,3-epoxypropoxy)propyl)diethoxymethyl-, Oxirane, 2-((3-(diethoxymethylsilyl)propoxy)methyl)-, DTXCID0024638, [3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane, diethoxy-3-glycidoxypropylmethylsilane, diethoxy(3-(glycidyloxy)propyl)methylsilane, 3-(GLYCIDOXY)PROPYLDIETHOXYMETHYLSILANE, 3-(GLYCIDOXYPROPYL)METHYLDIETHOXYSILANE, (3-GLYCIDYLOXY)PROPYLDIETHOXYMETHYLSILANE, .GAMMA.-GLYCIDOXYPROPYLMETHYLDIETHOXSILANE, (3-(2,3-Epoxypropoxy)propyl)diethoxymethylsilane, .GAMMA.-GLYCIDYLOXYPROPYLMETHYLDIETHOXYSILANE, (3-(GLYCIDYLOXY)PROPYL)METHYLDIETHOXYSILANE, .GAMMA.-GLYCIDYLOXYPROPYLMETHYLDIETHOXYSILANE, Silane, diethoxymethyl[3-(oxiranylmethoxy)propyl]-, Oxirane, 2-[[3-(diethoxymethylsilyl)propoxy]methyl]-, Diethoxy[3-(glycidyloxy)propyl]methyl silane, gamma-glycidyloxypropylmethyldiethoxysilane, GAMMA-GLYCIDOXYPROPYLMETHYLDIETHOXSILANE, (3-Glycidoxypropyl)methyldiethoxysilane, Diethoxy(3-glycidyloxypropyl)methylsilane, diethoxy-methyl-[3-(oxiran-2-ylmethoxy)propyl]silane, C11H24O4Si, (3-Glycidyloxypropyl)methyldiethoxysilane, 3-glycidoxypropylmethyldiethoxysilane, MFCD00046995, diethoxy(methyl){3-[(oxiran-2-yl)methoxy]propyl}silane, UNII-H04254P08T, [3-(2,3-Epoxypropoxy)propyl]methyldiethoxysilane, SCHEMBL43462, CHEMBL3182993, glycidoxypropylmethyldiethoxysilane, Tox21_302661, NSC252159, AKOS008901364, FS-5247, NCGC00256882-01, CAS-2897-60-1, DB-017974, (.gamma.-Glycidoxypropyl)methyldiethoxysilane, CS-0198099, D2632, Silane,3-epoxypropoxy)propyl]diethoxymethyl-, 3-(2,3-Epoxypropoxypropyl)Methyldiethoxysilane, 3-[Diethoxy(methyl)silyl]propyl Glycidyl Ether, D90094, Diethoxy(3-glycidyloxypropyl)methylsilane, 97%, S09100, 3-(2,3-Epoxypropoxy)Propyl]Diethoxymethylsilane, 3-(2,3-Epoxypropyloxy)PropylmethylDiethoxysilane, A819699, Q27279389, [3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane, [3-(2,3-EPOXYPROPOXY)PROPYL]METHYLDIETHOXYSILANE, GAMMA-GLYCIDOXYPROPYLMETHYLDIETHOXYSILANE, DIETHOXY(3-GLYCIDYLOXYPROPYL)METHYLSILANE, (3-GLYCIDOXYPROPYL)METHYLDIETHOXYSILANE, (3-GLYCIDYLOXYPROPYL)METHYLDIETHOXYSILANE, 3-[DIETHOXY(METHYL)SILYL]PROPYL GLYCIDYL ETHER, diethoxymethyl[3-(oxiranylmethoxy)propyl]-silan

Glycidoxypropylmethyldiethoxysilane, also known by its CAS number 2897-60-1, is a type of organosilane compound that contains both a reactive epoxy group (glycidyl/oxirane) and a hydrolyzable alkoxysilane group (diethoxymethylsilane). 
Because of this dual functionality, it serves as a chemical bridge between organic and inorganic materials, making it very useful in coatings, adhesives, sealants, and composite manufacturing.

Chemically, Glycidoxypropylmethyldiethoxysilane is a clear, colorless to light yellow liquid with a mild odor, and it typically has a low viscosity that makes it easy to blend with other resins or solvents. 
The molecule has two reactive ends: the epoxy group, which can undergo ring-opening reactions with amines, acids, and alcohols in organic resins, and the alkoxysilane group, which can hydrolyze in the presence of moisture to form silanol groups that bond strongly with inorganic materials such as glass, metals, silica, and ceramics. 

This dual reactivity makes it an effective coupling agent that enhances adhesion between materials that would not normally bond well.
In practical use, Glycidoxypropylmethyldiethoxysilane is widely applied in the coatings and paints industry, where it is added to improve adhesion, durability, and resistance to moisture. 
In the adhesive and sealant industry, it acts as a primer or additive that strengthens bonding between surfaces, such as metals and polymers, or glass and plastics. 

In the production of composite materials, especially fiberglass-reinforced plastics, it helps bind the resin matrix to the glass fibers, improving both the mechanical strength and the long-term stability of the composite.
Glycidoxypropylmethyldiethoxysilane is a cross linking agent. 
Glycidoxypropylmethyldiethoxysilane can be used to polymerize with other monomers to be special and high molecular compounds. 

Glycidoxypropylmethyldiethoxysilane is suitable as a cross-linking agent for RTV, as coupling agent for inorganic materials e.g. glass fiber and SiO2, as strengthening agent for laminated plastic products, etc.
Glycidoxypropylmethyldiethoxysilane is an epoxysilane which can be used as a silane coupling agent for the surface treatment of a variety of materials. 
These silanes can also be used as adhesion promoters by modifying the surface properties of the substrates and elastomeric materials.

Glycidoxypropylmethyldiethoxysilane is an organofunctional silane, meaning it contains both an organic reactive group (the epoxy/glycidyl group) and an inorganic reactive group (the alkoxysilane group). 
The epoxy group is located at the end of a three-carbon chain, while the silicon atom is bonded to two ethoxy groups and one methyl group. 
This combination of functionalities allows the compound to interact with a wide variety of materials, enabling it to act as a molecular coupling agent that improves compatibility between organic polymers and inorganic substrates.

Melting point: <0 °C
Boiling point: 122–126 °C at 5 mm Hg (lit.)
Density: 0.978 g/mL at 25 °C (lit.)
Vapor pressure: 0–7910 Pa at 25 °C
Refractive index: n20/D 1.431 (lit.)
Flash point: >230 °F
Storage temp.: 2–8 °C
Form: Liquid
Color: Colorless to almost colorless
Specific Gravity: 0.978
Water Solubility: 1.2–1000 g/L at 20 °C
Hydrolytic Sensitivity: 7: reacts slowly with moisture/water
BRN: 121965
InChIKey: OTARVPUIYXHRRB-UHFFFAOYSA-N
LogP: -0.7–2.7 at 20 °C

Glycidoxypropylmethyldiethoxysilane can be used as an adhesion promoter or a crosslinker in the coating and sealants industries.
Glycidoxypropylmethyldiethoxysilane’s suitable for the processing of furniture adhesives, automotive sealants and marine coatings.
Glycidoxypropylmethyldiethoxysilane can improve electrical properties of composites therefore it is also used for the preparation of electronic encapsulation and electronic packaging materials.

Glycidoxypropylmethyldiethoxysilane is a colorless transparent liquid that is compatible with most organic solvents and hydrolyzes in water. 
It is mainly used in unsaturated polyester composite materials to improve the mechanical, electrical, and light transmittance properties of composite materials, especially significantly improving the wet performance of composite materials.
Soaking fiberglass with the coupling agent can improve the mechanical strength and electrical properties of fiberglass reinforced composite materials in the wet state.

Glycidoxypropylmethyldiethoxysilane also finds application in the electronics industry, where it is used in encapsulants and insulating materials to improve electrical insulation, thermal stability, and moisture resistance. 
Because of its reactive epoxy group, it can be chemically incorporated into epoxy resins, polyurethanes, and other thermosetting polymers, enhancing their crosslinking density and performance properties.

Glycidoxypropylmethyldiethoxysilane is an epoxysilane which can be used as a silane coupling agent for the surface treatment of a variety of materials. 
These silanes can also be used as adhesion promoters by modifying the surface properties of the substrates and elastomeric materials.

One of the most important roles of Glycidoxypropylmethyldiethoxysilane is as a silane coupling agent, which means it helps create strong and durable chemical bonds between two otherwise incompatible surfaces, such as glass fibers and polymer resins. 
The alkoxy groups on the silicon atom can hydrolyze in the presence of moisture to form silanol groups, which can then chemically bond to the surface of materials like silica, metals, or ceramics. 

At the same time, the epoxy group can react with functional groups in resins such as epoxies, polyurethanes, and acrylics. 
This dual functionality significantly improves the mechanical strength, moisture resistance, and long-term durability of coatings, adhesives, and composites.
When added to formulations, Glycidoxypropylmethyldiethoxysilane can enhance multiple performance characteristics. 

For example, in protective coatings and paints, it improves adhesion to metal and glass surfaces, reduces peeling or delamination, and increases resistance to water and environmental degradation. 
In adhesives and sealants, it strengthens bonding at the interface between dissimilar materials, leading to joints that maintain stability even under stress or in humid conditions. 
In fiber-reinforced composites, it creates a stronger bond between the resin matrix and reinforcing fibers, which improves tensile strength, impact resistance, and dimensional stability of the final material.

Uses:
Glycidoxypropylmethyldiethoxysilane is an organo-functional silane that can be used as a coupling agent between inorganic fillers (powdered silicas, glass, fiberglass, ceramics, etc.) and a wide variety of polymers such as epoxy, melamine, phenolic and urethane resins, polystyrene plastic, acrylic sealants, butyl rubber and water soluble polymers that contain hydroxyl groups and/or primary or secondary amine groups.
Glycidoxypropylmethyldiethoxysilane, silane coupling agent KH-7180, is a versatile epoxy organo-reactive silane with two hydrolyzable ethoxy groups. 

Glycidoxypropylmethyldiethoxysilane provides shelf stable non-yellowing adhesion promoter performance while enhancing physical properties in latexes and waterborne adhesive and sealant systems.
Glycidoxypropylmethyldiethoxysilane can be used in the surface modification of a variety of particles such as cellulose nanocrystals, silica nanomaterials and other silicon based substrates. 

Glycidoxypropylmethyldiethoxysilane functionalizes these surfaces by attaching the epoxy-silane groups with the surface molecules.
Coverslips coated with diethoxy(3-glycidyloxypropyl)methyl silane were used as sample holders for electrostatically holding particles for optical microscopy.
Glycidoxypropylmethyldiethoxysilane may be used to introduce epoxy groups to Fe3O4SiO2 nanoparticles. 

Self assembled monolayer (SAMs) of diethoxy(3-Glycidoxypropylmethyldiethoxysilane could be formed on the oxide layer of silicon wafer to render them siloxane functionalities.
Glycidoxypropylmethyldiethoxysilane can be used in the surface modification of a variety of particles such as cellulose nanocrystals, silica nanomaterials and other silicon based substrates. 

Glycidoxypropylmethyldiethoxysilane functionalizes these surfaces by attaching the epoxy-silane groups with the surface molecules.
Glycidoxypropylmethyldiethoxysilane is extensively used in the coatings and paints industry as a performance-enhancing additive because its dual functional groups allow it to improve adhesion between organic resins and inorganic surfaces such as glass, metals, and ceramics, resulting in coatings that are more durable, resistant to peeling, and less susceptible to moisture damage over time.

Glycidoxypropylmethyldiethoxysilane is incorporated into primers, protective coatings, and specialty paints to strengthen the chemical bonding between the substrate and the paint layer, which also enhances scratch resistance, weathering resistance, and long-term stability in outdoor or harsh environments.
In the adhesive and sealant industry, Glycidoxypropylmethyldiethoxysilane functions as a coupling agent that bridges dissimilar materials, such as metals, glass, plastics, or ceramics, which would otherwise have poor adhesion. 

Glycidoxypropylmethyldiethoxysilanes epoxy group reacts with polymer chains in the adhesive formulation, while its silane group bonds to inorganic surfaces, creating a strong, durable, and moisture-resistant interface. 
This makes it particularly useful in structural sealants, silicone adhesives, and epoxy formulations, where high mechanical strength and longevity are critical.
Glycidoxypropylmethyldiethoxysilane is widely used in the manufacture of composite materials, particularly fiber-reinforced plastics, where it improves the bond between glass fibers or mineral fillers and polymer matrices. 

By chemically linking the reinforcing fibers to the resin, Glycidoxypropylmethyldiethoxysilane enhances the tensile strength, impact resistance, and dimensional stability of composites, making them suitable for applications in the aerospace, automotive, and construction industries, where materials must withstand mechanical stress, temperature fluctuations, and exposure to chemicals.
In the electronics industry, Glycidoxypropylmethyldiethoxysilane is used in encapsulants, insulating materials, and protective coatings, where it contributes to excellent adhesion to substrates, improved thermal stability, and resistance to moisture penetration. 

Glycidoxypropylmethyldiethoxysilane helps prevent delamination and degradation of electronic components over time, which is critical for ensuring the long-term performance and reliability of devices such as circuit boards, sensors, and semiconductor modules.
Glycidoxypropylmethyldiethoxysilane is also employed in plastics and polymer formulations to improve the compatibility between inorganic fillers (such as silica, alumina, or clay) and organic polymer matrices. 

By acting as a chemical bridge, it improves mechanical strength, dimensional stability, and thermal performance of plastics and enhances flame retardancy in certain formulations. 
Glycidoxypropylmethyldiethoxysilane is used in high-performance plastics, elastomers, and specialty polymer composites where durability and stability are essential.

Safety Profile:
Glycidoxypropylmethyldiethoxysilane is considered a moderately hazardous chemical, primarily due to the presence of its reactive epoxy (glycidyl) group, which can act as an irritant and sensitizer. 
Direct contact with the skin may cause irritation, redness, or dermatitis, particularly in individuals with sensitive skin, while repeated or prolonged exposure can potentially lead to allergic skin reactions. 

Eye contact can result in burning, redness, or irritation, and accidental splashes should be rinsed immediately with copious amounts of water. 
Inhalation of vapors, mists, or fine aerosols may cause respiratory irritation, coughing, or throat discomfort, and in poorly ventilated areas, prolonged exposure could potentially lead to more significant respiratory sensitization or discomfort. 
Although Glycidoxypropylmethyldiethoxysilane is not classified as acutely toxic in small amounts, ingestion could cause gastrointestinal irritation, nausea, or vomiting, and it should never be ingested intentionally.

From an environmental perspective, Glycidoxypropylmethyldiethoxysilane can pose risks to aquatic life if released in significant quantities, because its reactive silane and epoxy groups can hydrolyze or react in water, potentially forming compounds that are harmful to fish and other aquatic organisms. 
While it is not highly persistent, large-scale spills or improper disposal can result in localized contamination and disruption of aquatic ecosystems.
Therefore, measures should be taken to prevent release into waterways and to follow proper waste management protocols according to regulatory guidelines.

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