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Gynostemma P. (Jiaogulan) extract is a climbing vine native to the mountainous regions of Asia, particularly China, Korea, and Japan.
Gynostemma P. (Jiaogulan) extract is sometimes referred to as "Southern Ginseng" due to its adaptogenic properties, similar to those of ginseng.
Gynostemma P. (Jiaogulan) extract, in the family Cucurbitaceae, which includes cucumbers, gourds, and melons.
Cas Number: 8047-15-2
Molecular Formula: C27H42O3
EINECS Number: 232-462-6
Synonyms: sasanquasaponin, SAPONIN, 8047-15-2, AS-83333, DA-67405, 10-[(3-{[4,5-dihydroxy-6-(hydroxymethyl)-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-4-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]oxan-2-yl)oxy]-2-hydroxy-4,5,9,9,13,20-hexamethyl-24-oxahexacyclo[15.5.2.0(1),(1)?.0?,(1)?.0?,(1)?.0?,(1)(3)]tetracosane-20-carbaldehyde, 10-[3-[4,5-dihydroxy-6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-2-yl]oxy-2-hydroxy-4,5,9,9,13,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracosane-20-carbaldehyde
Gynostemma P. (Jiaogulan) extract, commonly known as Jiaogulan, is an herb used in traditional Chinese medicine.
Gynostemma P. (Jiaogulan) extract is a secondary metabolite that facilitates the penetration of proteins through the cell membrane.
Studies indicate that saponins are amphipathic glycosides, which can act as hemolytic agents.
Research indicates that Saponin displays antinociceptive, anti-inflammatory and antipyretic activities, which may be due to its nonglycosidic moiety, sapogenin.
Gynostemma P. (Jiaogulan) extract can also be used in environmental research to recover chromium and other metals from sludge samples.
Additional studies indicate that Gynostemma P. (Jiaogulan) extract is useful in immunoassays since it can stimulate the Th1 immune response and the production of cytotoxic T-lymphocytes in response to exogenous antigens.
Gynostemma P. (Jiaogulan) extracts are phytochemicals which can be found in most vegetables, beans and herbs.
The best known sources of saponins are peas, soybeans, and some herbs with names indicating foaming properties such as soapwort, saoproot, soapbark and soapberry.
Commercial saponins are extracted mainly from Yucca schidigera and Quillaja saponaria.
Its fruit is a small purple inedible gourd.
Gynostemma P. (Jiaogulan) extract is a climbing vine, attaching itself to supports using tendrils.
The serrated leaflets commonly grow in groups of five (as in G. pentaphyllum) although some species can have groups of three or seven leaflets.
Gynostemma P. (Jiaogulan) extract is dioecious, meaning each plant exists either as male or female.
Therefore, if seeds are desired, both a male and female plant must be grown.
Gynostemma P. (Jiaogulan) extract is a plant that grows wild in many parts of Asia. It's sometimes called Southern Ginseng or Miracle Plant.
Gynostemma P. (Jiaogulan) extract contains substances that might help reduce cholesterol levels.
Gynostemma P. (Jiaogulan) extract for high cholesterol, diabetes, liver disease, obesity, and many other conditions, but there is no good scientific evidence supporting most of these uses.
Gynostemma P. (Jiaogulan) extract with miracle fruit, or with aloe or gymnema, which are also sometimes called miracle plant.
Also, don't confuse Gynostemma P. (Jiaogulan) extract with other plants that are called ginseng, including American ginseng, blue cohosh, canaigre, codonopsis, eleuthero, Panax ginseng, and Panax notoginseng.
Modern recognition of the plant outside of China originated from research in sugar substitutes.
Continued research has described several saponins (gypenosides) comparable or identical to those found in ginseng.
Panax ginseng contains ginsenosides, while gypenoside saponins have been found in Gynostemma P. (Jiaogulan) extract.
Other constituents include sterols and triterpenols.
Gynostemma P. (Jiaogulan) extract have been extracted from its leaves.
While there have been in vitro studies on toxicity, there have been no clinical trials providing high-quality clinical evidence about its efficacy and safety; no information exists about human toxicity.
Gynostemma P. (Jiaogulan) extract tea of the highest grade (no stems). Made from the dried leaves of the plant scientifically known as Gynostemma Pentaphyllum, a remarkable herb native to South China and some other Asian countries.
Due to its beneficial properties, this plant has a long history of usage.
Gynostemma P. (Jiaogulan) extract's been traditionally used as a natural remedy for everything from stress to high cholesterol.
The original name "Jiao Gu Lan" itself is of Chinese origin, where "Jiao" means twisting or winding, "Gu" means vine, and "Lan" refers to blue or blueish, capturing its appearance as a twining, bluish vine.
In China, Jiaogulan is often called, which translates to "Miracle Grass" or "Immortality Herb."
This term harks back to its traditional usage for longevity and a wide array of health benefits.
Gynostemma P. (Jiaogulan) extract is also referred to as "Southern Ginseng" due to its adaptogenic properties similar to those of true ginseng (Panax Ginseng).
Adaptogens are known to improve the body's response to stress, enhance stamina, and boost overall well-being.
The Japanese name for Gynostemma P. (Jiaogulan) extract is "Amachazuru" which translates to 'sweet tea vine,' reflecting both its taste and its physical form.
Gynostemma P. (Jiaogulan) extract comes from the cucumber (Cucurbitaceae) family which proves it to be a caffeine-free beverage.
This family predominantly contains a different set of phytochemicals, including cucurbitacins and carotenoids, which have their own set of biological functions but do not include the stimulant properties of caffeine.
Gynostemma P. (Jiaogulan) extract tea has a vegetal-grassy, “greenish” taste with quite a rich flavor palette.
In the foreground you can notice a minty chill with a slightly noticeable sparkling bitterness, against the backdrop of natural sweetness.
Gynostemma P. (Jiaogulan) extract is somewhat reminiscent of the taste of stevia or licorice, but more interesting, multifaceted and deep.
There are also some salty notes, which indicates a high degree of minerality.
Overall, Gynostemma P. (Jiaogulan) extract's a balanced flavor that leaves a pleasant, sweet note on your tongue after each sip.
But it is mainly thanks to its health benefits, that Gynostemma P. (Jiaogulan) extract tea has become a respected drink even among true tea lovers.
The main bioactive components are flavonoids and saponins.
For example, Gynostemma P. (Jiaogulan) extract contains gypenosides (type of saponins), which are structurally similar to the catechins found in green tea and to the ginsenosides found in real Ginseng.
These compounds contribute to its adaptogenic and antioxidant properties.
The list of Gynostemma P. (Jiaogulan) extract’s beneficial properties is even longer and includes hypolipidemic, anti-cancer, cardioprotective, hepatoprotective, neuroprotective, anti-diabetic and anti-inflammatory effects.
Some studies suggest that Jiaogulan may help regulate blood sugar levels, which could be beneficial for managing diabetes.
Gynostemma P. (Jiaogulan) extract may support liver function and protect against liver damage due to its antioxidant and anti-inflammatory properties.
There is some evidence to suggest that Jiaogulan may assist with weight management by improving metabolic function and reducing fat accumulation.
Gynostemma P. (Jiaogulan) extract has been used in traditional Chinese medicine for centuries to promote longevity, vitality, and overall well-being.
Gynostemma P. (Jiaogulan) extract is available in various forms, including capsules, tablets, teas, and tinctures.
Modern research continues to explore its potential health benefits.
Gynostemma P. (Jiaogulan) extract is generally considered safe when used appropriately.
However, it's important to use it under the guidance of a healthcare provider.
Rare side effects may include gastrointestinal discomfort or allergic reactions.
Gynostemma P. (Jiaogulan) extract may interact with certain medications, including those for blood pressure, blood sugar, and anticoagulants.
Consult a healthcare provider before using Gynostemma P. (Jiaogulan) extract if are on any medications or have existing health conditions.
Melting point: 158℃
Boiling point: 101.9℃[at 101 325 Pa]
Density: 1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.)
vapor pressure: 0.009Pa at 105℃
storage temp.: Store at RT.
form: Tan solid
color: Yellow crystalline
Odor: Odorless
Water Solubility: Soluble in cold water.
Merck: 14,8365
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.24 at 20℃
Gynostemma P. (Jiaogulan) extract have many health benefits. Studies have illustrated the beneficial effects on blood cholesterol levels, cancer, bone health and stimulation of the immune system.
Most scientific studies investigate the effect of saponins from specific plant sources and the results cannot be applied to other saponins.
Gynostemma P. (Jiaogulan) extract bind with bile salt and cholesterol in the intestinal tract.
Bile salts form small micelles with cholesterol facilitating its absorption.
Gynostemma P. (Jiaogulan) extract cause a reduction of blood cholesterol by preventing its re-absorption.
Studies have shown that saponins have antitumor and anti-mutagenic activities and can lower the risk of human cancers, by preventing cancer cells from growing.
Gynostemma P. (Jiaogulan) extract seem to react with the cholesterol rich membranes of cancer cells, thereby limiting their growth and viability.
Gynostemma P. (Jiaogulan) extract to fight infections by parasites.
When ingested by humans, saponins also seem to help our immune system and to protect against viruses and bacteria.
Studies with ovariectomized induced rats have shown that some Gynostemma P. (Jiaogulan) extract, such as the steroidal saponins from Anemarrhena asphodeloides, a Chinese herb, have a protective role on bone loss.
The non-sugar part of Gynostemma P. (Jiaogulan) extract have also a direct antioxidant acitivity, which may results in other benefits such as reduced risk of cancer and heart diseases.
A type of toxic glycoside that forms a frothy colloidal solutionon shaking with water.
Gynostemma P. (Jiaogulan) extract occur in many plants (such as horsechestnut).
They break down red blood cells and have been used for poisoning fish. On hydrolysis they yield a variety of sugars.
These are Gynostemma P. (Jiaogulan) extract that are thought to be responsible for many of Jiaogulan's therapeutic effects.
These have antioxidant properties that help protect cells from oxidative damage.
These can have immune-boosting effects and support overall health.
Gynostemma P. (Jiaogulan) extract is known for its adaptogenic effects, which help the body adapt to stress and maintain balance.
Gynostemma P. (Jiaogulan) extract may improve overall resilience and endurance.
Gynostemma P. (Jiaogulan) extract is believed to support cardiovascular health by improving blood circulation, lowering blood pressure, and reducing cholesterol levels.
Gynostemma P. (Jiaogulan) extract may help prevent heart disease and support overall heart function.
The herb has immune-boosting properties, potentially enhancing the body's ability to fight infections and diseases.
Gynostemma P. (Jiaogulan) extract has strong antioxidant properties, which help neutralize free radicals and reduce oxidative stress.
This can help protect cells from damage and support overall health.
The herb may help reduce inflammation in the body, which is beneficial for conditions associated with chronic inflammation.
Uses Of Gynostemma P. (Jiaogulan) extract:
The plant is used in folk medicine, typically as a herbal tea, but may be used as an alcohol extract or in dietary supplements.
Gynostemma P. (Jiaogulan) extract has not seen widespread use in traditional Chinese medicine, being adopted only in the past 20 years, and grows mainly in Guizhou province.
In the European Union, Gynostemma P. (Jiaogulan) extract is considered a novel food following a 2012 court ruling that prohibited its sale as food.
Limited clinical studies have been conducted to support therapeutic applications.
Gynostemma P. (Jiaogulan) extract may have a role in the management of type 2 diabetes, obesity, fatty liver disease, immune response (such as asthma), and cancer. G. pentaphyllum extracts may also have a place in beneficial antioxidant therapy.
Gynostemma P. (Jiaogulan) extracts are steroid or triterpenoid glycosides found in wild or cultivated plants, lower marine animals and some bacteria.
Gynostemma P. (Jiaogulan) extract can also activate the mammalian immune system, which have led to significant interest in their potential as vaccine adjuvants.
Their unique capacity to stimulate both the Th1 immune response and the production of cytotoxic Tlymphocytes (CTLs) against exogenous antigens makes them ideal for use in subunit vaccines and vaccines directed against intracellular pathogens as well as for therapeutic cancer vaccines.
Gynostemma P. (Jiaogulan) extract are used in permeabilization of cell membranes and separation of low molecular weight contaminants and as an adjuvant in vaccine development.
Glycoside widely distributed in plants.
Gynostemma P. (Jiaogulan) extract that forms oil-in-water emulsions and acts as protective colloid. Used for the direct determination of metals in milk by flame atomic-absorption spectrophotometry.
Also used in permeabilization of cell membranes and separation of low molecular weight contaminants, and as an adjuvant in vaccine development.
Gynostemma P. (Jiaogulan) extract is known for its adaptogenic effects, which help the body cope with stress and maintain balance.
It may improve overall resilience and endurance.
Gynostemma P. (Jiaogulan) extract is believed to support cardiovascular health by improving blood circulation.
Gynostemma P. (Jiaogulan) extract may help lower blood pressure and reduce cholesterol levels.
Gynostemma P. (Jiaogulan) extract may contribute to overall heart health and prevent heart disease.
The herb has properties that may enhance the body's immune response, helping it fight infections and diseases.
Gynostemma P. (Jiaogulan) extract contains antioxidants that neutralize free radicals, reducing oxidative stress and protecting cells from damage.
It may help reduce inflammation in the body, which can be beneficial for managing conditions associated with chronic inflammation.
Some studies suggest that Gynostemma P. (Jiaogulan) extract may help regulate blood sugar levels, which can be beneficial for individuals with diabetes.
Gynostemma P. (Jiaogulan) extract may support liver function and protect against liver damage due to its antioxidant and anti-inflammatory properties.
It may assist with weight management by improving metabolic function and reducing fat accumulation.
Traditionally, Jiaogulan has been used to promote longevity and overall well-being, contributing to increased vitality and a longer, healthier life.
Gynostemma P. (Jiaogulan) extract has been used to promote healthy digestion and relieve symptoms of digestive discomfort.
Safety Profile Of Gynostemma P. (Jiaogulan) extract:
Some individuals may experience gastrointestinal discomfort, including nausea, upset stomach, or diarrhea.
Rarely, it may cause other digestive issues such as bloating or gas.
Allergic reactions to Jiaogulan are rare but can include symptoms such as rashes, itching, or swelling.
Though uncommon, severe allergic reactions can occur and may require medical attention.
Gynostemma P. (Jiaogulan) extract may interact with blood-thinning medications (like warfarin or aspirin), potentially increasing the risk of bleeding.
Gynostemma P. (Jiaogulan) extract could potentially interact with medications used to manage blood pressure, affecting their efficacy.
There is a potential for interaction with diabetes medications, which might affect blood sugar levels.
