HAWTHORN LEAF EXTRACT

Hawthorn Leaf extract is derived from the leaves of the hawthorn plant, typically from the species Crataegus monogyna or Crataegus laevigata. 
Hawthorn Leaf extract is commonly used in herbal medicine and dietary supplements for its various health benefits.
Hawthorn Leaf extract is a flowering shrub in the rose family. 

Cas Number: 36052-37-6

Synonyms: Alpinetin, 36052-37-6, (S)-7-Hydroxy-5-methoxy-2-phenylchroman-4-one, (-)-alpinetin, (S)-7-Hydroxy-5-methoxyflavanone, 5-O-Methylpinocembrin, Alpinetin, (S)-, 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-phenyl-, (2S)-, (2S)-7-hydroxy-5-methoxy-2-phenyl-2,3-dihydrochromen-4-one, SX3EL59QD8, 5-Methoxy-7-hydroxyflavanone, Alpinetin,(S), (S)-ALPINETIN, UNII-SX3EL59QD8, CHEMBL254825, SCHEMBL1460821, HY-N0625A, DTXSID80189620, CHEBI:229049, QQQCWVDPMPFUGF-ZDUSSCGKSA-N, (2s)-7-hydroxy-5-methoxyflavanone, MFCD00238532, s3875, (2S)-7-Hydroxy-5-methoxy-2-phenyl-2,3-dihydro-4H-1-benzopyran-4-one, AKOS015896758, CCG-267158, AC-34711, AS-56086, CS-0016792, A874456, (2S)-7-hydroxy-5-methoxy-2-phenyl-chroman-4-one, Q-100430, Q4735601, (2S)-2,3-DIHYDRO-7-HYDROXY-5-METHOXY-2-PHENYL-4H-1-BENZOPYRAN-4-ONE, 4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-HYDROXY-5-METHOXY-2-PHENYL-, (S)-

Hawthorn Leaf extract common species include Crataegus monogyna, Crataegus laevigata, and Crataegus oxyacantha.
The Hawthorn Leaf extract, berries, and flowers are used as medicine. 
They contain chemicals called flavonoids, which have antioxidant effects. Hawthorn also seems to improve blood circulation and affect blood flow from the heart.

People most commonly use Hawthorn Leaf extract for chest pain, heart failure, blood circulation problems, high blood pressure, anxiety, and many other conditions, but there is no good scientific evidence to support these uses.
Hawthorn Leaf extract such as tinctures or essences offer a convenient alternative to herbal teas. 
Many are used in food, food supplements, cosmetics, and as an ingredient by herbalists in bespoke formulas. A herbal food supplement.

Hawthorn Leaf extract, derived from the Crataegus species, is recognized for its broad spectrum of health benefits, particularly in cardiovascular and liver health, antioxidative properties, and potential as an anti-aging agent. 
Recent studies have illuminated these diverse benefits.
Hawthorn Leaf extract has been found to offer vascular protective effects in cardiovascular diseases, aiding in the management of heart health.

A study demonstrated that hawthorn fruit extract could ameliorate oxidative damage in neuronal cells and prolong lifespan via the IIS signaling pathway, indicating its antioxidative and anti-aging properties.
Hawthorn Leaf extract plays potential roles in combating various liver diseases, showing promise in liver health management.

Research highlights the diverse biomedical applications of hawthorn, showcasing its versatility in health promotion.
Studies have shown that dietary hawthorn extracts can positively affect lipid metabolism, skin coloration, and gut health.
Hawthorn Leaf extract has been identified for its antiplatelet aggregation and antithrombotic benefits, contributing to cardiovascular health.

Hawthorn Leaf extract has been observed to affect serum antioxidant activity, impacting cardiac indicators and growth performance, particularly in stress conditions.
Such as quercetin and hyperoside, which are believed to have antioxidant and anti-inflammatory properties.
These are known for their potential antioxidant benefits.

Hawthorn Leaf extracts may help strengthen blood vessels and improve circulation.
Hawthorn Leaf extract is available in various forms, including:
Commonly used for its cardiovascular benefits.

Liquid extracts that can be taken directly or mixed with water.
Made from dried hawthorn leaves and berries.
While generally considered safe, hawthorn leaf extract can cause some side effects, including:

Some users may experience headaches.
Hawthorn Leaf extract may interact with certain medications, particularly those used for heart conditions.
Hawthorn Leaf extract's important to consult with a healthcare provider before starting any new supplement, especially if are on medication or have existing health conditions.

Melting point: 223-224°C
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO : 50 mg/mL (184.99 mM; Need ultrasonic)
form: powder
Boiling point: 494.9±45.0 °C(Predicted)
Density: 1.284±0.06 g/cm3(Predicted)
pka: 7.34±0.40(Predicted)
color: White

Hawthorn Leaf extract is a common thorny shrub in the rose family that grows up to 5 feet tall on hillsides and in sunny wooded areas throughout the world. 
Hawthorn Leaf extracts flowers bloom in May, growing in small white, red, or pink clusters. 
Small berries, called haws, sprout after the flowers and are usually red when ripe, but they may also be black.

Hawthorn Leaf extract has been used to treat heart disease as far back as the 1st century. 
By the early 1800s, American doctors were using it to treat circulatory disorders and respiratory illnesses. 
Traditionally, the berries were used to treat heart problems ranging from irregular heartbeat, high blood pressure, chest pain, hardening of the arteries, and heart failure.

There is even research to suggest that Hawthorn Leaf extract might be effective when used in the treatment of mild-to-moderate heart failure. 
Animal and laboratory studies report that hawthorn contains antioxidants, including oligomeric procyanidins (OPCs, also found in grapes) and quercetin.
Antioxidants are substances that destroy free radicals, which are compounds in the body that damage cell membranes, tamper with DNA, and even cause cell death. 

Free radicals occur naturally in the body and grow in number as we age. 
Environmental toxins (including ultraviolet light, radiation, smoking, some medicines, and air pollution) can also increase the number of these damaging particles.

Scientists believe free radicals contribute to the aging process (such as wrinkling), as well as the development of a number of health problems, including cancer and heart disease. 
Antioxidants in hawthorn may help stop some of the damage from free radicals, especially when it comes to heart disease.

Uses Of Hawthorn Leaf extract:
Hawthorn Leaf extract is used to help protect against heart disease and help control high blood pressure and high cholesterol. 
Both animal and human studies suggest hawthorn increases coronary artery blood flow, improves circulation, and lowers blood pressure. 
Hawthorn Leaf extract has also been used on the skin to treat boils and skin sores.

Hawthorn Leaf extract is identified as a potential natural uridine-cytidine kinase 2 (UCK2) inhibitor. 
Possesses anti-bacterial, anti-tumor and other important therapeutic activities.
Hawthorn leaf extract is widely used to support heart health. 

Hawthorn Leaf extract is believed to improve blood flow to the heart, strengthen the heart muscle, and help in managing symptoms of heart disease, including angina and heart failure.
It may help in regulating blood pressure by improving blood vessel function and reducing blood pressure levels.
Some studies suggest that hawthorn extract can help lower cholesterol levels, which is beneficial for cardiovascular health.

Hawthorn Leaf extract has been used to treat digestive issues such as indigestion and stomach cramps.
Hawthorn Leaf extract might have mild sedative effects, helping to reduce anxiety and stress.
Hawthorn Leaf extract is commonly used to support heart function, especially in cases of mild to moderate heart failure. 

It can help improve symptoms like shortness of breath and fatigue.
It may help alleviate chest pain (angina) by improving blood flow to the heart.
Some studies suggest that it can enhance blood flow to the heart muscle, helping to reduce symptoms of myocardial ischemia (reduced blood flow to the heart).

Hawthorn Leaf extract may assist in lowering blood pressure by relaxing blood vessels and improving circulation.
Hawthorn Leaf extract supports the health of blood vessels, potentially aiding in the management of hypertension.
Some research indicates that hawthorn extract can help lower levels of LDL (bad) cholesterol and triglycerides, which contributes to better cardiovascular health.

Hawthorn Leaf extract is sometimes used to help relieve symptoms of indigestion and promote healthy digestion.
It may also help alleviate stomach cramps.
Hawthorn leaf extract has mild sedative properties and may help reduce anxiety and stress, contributing to a sense of calm.

The flavonoids and proanthocyanidins in hawthorn extract have antioxidant properties that help protect cells from oxidative damage.
By supporting cardiovascular health and providing antioxidant benefits, hawthorn leaf extract may indirectly support overall immune system function.

Some studies suggest that hawthorn extract may improve exercise performance by enhancing blood flow and oxygen delivery to muscles.
Hawthorn Leaf extract may help manage some symptoms associated with menopause, though evidence is limited.

Safety Profile Of Hawthorn Leaf extract:
Hawthorn Leaf extract may lower blood pressure, which could cause hypotension (low blood pressure) in some individuals, especially if taken in high doses or with other blood pressure-lowering medications. 
There is some concern that hawthorn could affect heart rate or rhythm, particularly in people with heart conditions.
Some users might experience nausea, stomach upset, or diarrhea. 

These symptoms are generally mild but can be bothersome.
Rarely, individuals might experience allergic reactions such as rashes, itching, or swelling. 
Severe allergic reactions are uncommon but can occur.