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HDO 1,6-Hexanediol is a waxy hygroscopic solid compound that is white in colour.
HDO 1,6-Hexanediol is a linear diol that contains two primary hydroxyl groups that are located at the terminal.
HDO 1,6-Hexanediol’s linear hydrocarbon chain enables the compound to have enhanced hardness and flexibility of polyesters.
CAS Number: 629-11-8
Molecular Formula: C6H14O2
Molecular Weight: 118.17
EINECS Number: 211-074-0
Synonyms: 1,6-Dihidroxihexano, 1,6-Dihydroxyhexane, 1,6-Hexanediol, 1,6-hexanodiol, 16-Dihydroxyhexane, 16-Hexylene glycol, 4-01-00-02556 (Beilstein Handbook Reference), 629-11-8, AI3-03307, BRN 1633461, C6-H14-O2, C6H14O2, CCRIS 8982, EC 211-074-0, EINECS 211-074-0, HDO, HSDB 6488, Hexamethylene glycol, Hexamethylenediol, Hexametilenodiol, Hexane-1,6-diol, Hexanediol, 1,6-; (Hexamethylene glycol), NSC 508, UNII-ZIA319275I, alpha w-Hexanediol, alpha,omega-Hexanediol, glicol hexametileno, w-Hexanediol, HEXANE-1,6-DIOL;HEXAMETHYLENE GLYCOL;HDO(R);1,6-DIHYDROXYHEXANE;1,6-HEXANEDIOL;1,6-HDO;1,6-HEXYLENE GLYCOL;HDO 1,6-Hexanediol Flakes
HDO 1,6-Hexanediol is utilized in the extending chains in polyurethanes.
HDO 1,6-Hexanediol is produced by a propriety process that is based on BASF technology.
Industrially, HDO 1,6-Hexanediol is prepared by the hydrogenation of adipic acid.
Conversely, in the laboratory, HDO 1,6-Hexanediol can be synthesized by the reduction of adipic acid with lithium aluminum hydride.
HDO 1,6-Hexanediol as a building block for resins used for adhesives providing flexibility and adhesion
HDO 1,6-Hexanediol as a building block for the production of polyester and polyurethane resins. Good balance between hardness and flexibility, adhesion, weatherability or hydrolysis resistance.
HDO 1,6-Hexanediol is also applied in the manufacturing process of radiation-curable coatings, polycarbonate diols and as a reactive thinner for the formulation of epoxy systems which are used for the efficient production of rotor blades for modern wind turbines.
HDO 1,6-Hexanediol is an organic compound with the formula (CH2CH2CH2OH)2.
It is a colorless water-soluble solid.
HDO 1,6-Hexanediol is prepared by the hydrogenation of adipic acid or its esters.
Laboratory preparation could be achieved by reduction of adipates with lithium aluminium hydride, although this method is impractical on a commercial scale.
As HDO 1,6-Hexanediol contains the hydroxyl group, it undergoes the typical chemical reactions of alcohols such as dehydration, substitution, esterification.
Dehydration of HDO 1,6-Hexanediol gives oxepane, 2-methyltetrahydropyran and 2-ethyltetrahydrofuran.
Corresponding thiophene and pyrrolidone can be made by reacting HDO 1,6-Hexanediol with hydrogen sulfide and ammonia respectively.
HDO 1,6-Hexanediol is a building block for saturated polyesters and polyurethanes acrylic esters of 1,6-Hexanediol are used as reactive diluent for UV-coatings.
HDO 1,6-Hexanediol is used in polyesters for solvent-borne paints, in stoving enamels for automotive coatings, for can-& coil-coating and for general applications.
It is preferentially used in two-component paints for plastic coatings and repair coatings.
HDO 1,6-Hexanediol is suitable for polyester plasticizers and in soft segments for polyurethanes.
HDO 1,6-Hexanediol shows an optimum balance of flexibility and toughness (excellent flexibility in combination with sufficient hardness) in polyesters and polyurethane.
HDO 1,6-Hexanediol contains terminally located hydroxyl groups which results in rapid and simultaneous reactions in the formation of numerous disubstituted products.
HDO 1,6-Hexanediol is used in synthesis of specialty chemicals.
Applications include manufacturing of polymers such as polyurethanes, polyesters, and polycarbonate diols.
Hexane-1,6-diol is a diol that is hexane substituted by hydroxy groups at positions 1 and 6.
It is a diol and a primary alcohol.
HDO 1,6-Hexanediol derives from a hydride of a hexane.
HDO 1,6-Hexanediol’s long hydrocarbon chain gives the compound the ability to improve the flexibility and hardness of polyesters.
It is also used as a chain extender in polyurethanes.
The resulting modified polyurethane has high resistance to hydrolysis as well as mechanical strength, but with a low glass transition temperature.
HDO 1,6-Hexanediol is raw material for polyurethane coatings, polyester resins and polycarbonatediol resins.
HDO 1,6-Hexanediol is also used as a raw material to make reactive diluent for epoxy resin.
The chemical structure of 1,6-hexanediol, which contains terminally located hydroxyl groups, makes it highly reactive and useful for the manufacture of a variety of derivatives.
It is also used as a raw material for a UV curing material, which is expanding market share as an environmentally friendly coating material that do not use solvents.
HDO 1,6-Hexanediol is a waxy hygroscopic solid compound that is white in colour.
The compound is a linear diol that contains two primary hydroxyl groups that are located at the terminal.
HDO 1,6-Hexanediol’s linear hydrocarbon chain enables the compound to have enhanced hardness and flexibility of polyesters.
Moreover, this property is utilized in the extending chains in polyurethanes.
HDO 1,6-Hexanediol is produced by a propriety process that is based on BASF technology. Industrially, it is prepared by the hydrogenation of adipic acid.
Conversely, in the laboratory, HDO 1,6-Hexanediol can be synthesized by the reduction of adipic acid with lithium aluminum hydride.
HDO 1,6-Hexanediol is an important precursor in the polymer industry.
The current industrial route to produce HDO 1,6-Hexanediol involves energy intensive and hazardous multistage (four-pot–four-step) chemical reactions using cyclohexane (CH) as the starting material, which leads to serious environmental problems.
HDO 1,6-Hexanediol under mild conditions in a one-pot–one-step manner.
This cascade biocatalysis operates by using a microbial consortium composed of three E. coli cell modules, each containing the necessary enzymes.
The cell modules with assigned functions were engineered in parallel, followed by combination to construct E. coli consortia for use in biotransformations.
The engineered E. coli consortia, which contained the corresponding cell modules, efficiently converted not only CH or cyclohexanol to HDO 1,6-Hexanediol, but also other cycloalkanes or cycloalkanols to related dihydric alcohols.
In conclusion, the newly developed biocatalytic process provides a promising alternative to the current industrial process for manufacturing HDO 1,6-Hexanediol and related dihydric alcohols.
HDO 1,6-Hexanediol can improve the hardness and flexibility of polyesters as it contains a fairly long hydrocarbon chain.
In polyurethanes, HDO 1,6-Hexanediol is used as a chain extender, and the resulting modified polyurethane has high resistance to hydrolysis as well as mechanical strength, but with a low glass transition temperature.
It is also an intermediate to acrylics, adhesives, and dyestuffs.
Unsaturated polyester resins have also been made from HDO 1,6-Hexanediol, along with styrene, maleic anhydride and fumaric acid
HDO 1,6-Hexanediol long hydrocarbon chain gives the compound the ability to improve the flexibility and hardness of polyesters.
It is also used as a chain extender in polyurethanes.
The resulting modified polyurethane has high resistance to hydrolysis as well as mechanical strength, but with a low glass transition temperature.
Additionally, HDO 1,6-Hexanediol is used as an intermediate in the manufacture of acrylics, adhesives, and dyestuffs.
Styrene, maleic anhydride, fumaric acid, and unsaturated polyester resins have also been made from HDO 1,6-Hexanediol.
HDO 1,6-hexanediol is a highly valued linear diol which contains two primary hydroxyl groups which are terminally located.
This configuration results in a rapid and simultaneous reaction in the formation of numerous di-substituted products.
HDO 1,6-Hexanediol is widely used by industry in such applications as polyesters for polyurethane elastomers, coatings, adhesives, and polymeric plasticizers.
HDO 1,6-Hexanediol is a valuable intermediate product for the chemical industry.
It finds applications in a variety of polymeric systems and is also used in the synthesis of specialty chemicals.
This linear diol contains two primary hydroxyl groups which are terminally located.
This configuration results in a rapid and simultaneous reaction in the formation of numerous di-substituted products.
HDO 1,6-Hexanediol is used in the production of polyesters for polyurethane elastomers, coatings,adhesives and polymeric plasticizers.
HDO 1,6-Hexanediol undergoes all reactions typical of primary alcohols.
Reactions with difunctional acids, diisocyanates and phosgene are of known industrial importance.
A relatively high boiling point and heat stability permit elevated temperature reactions, while solubility in water provides an easy means to remove traces of the unreacted diol.
There is little tendency to cyclize or form unsaturated products at elevated temperatures.
HDO 1,6-Hexanediol is used to produce industrial coatings including low volatile organic compound formulations, polyurethanes, adhesives, and cosmetics.
HDO 1,6-Hexanediol also acts as a reactive thinner, for example in the formulation of epoxy systems used for the efficient production of rotor blades for modern wind turbines and building components for automotive lightweight applications.
HDO 1,6-Hexanediol performs in a variety of applications such as raw materials of surface coatings and intermediates of PU, Adhesives and Cosmetics.
HDO 1,6-Hexanediol is also used in polymeric plasticizers, unsaturated polyesters and dyestuffs. </p>
HDO 1,6-Hexanediol is the raw material for polyurethane coatings, polyester resins and polycarbonatiol resins.
HDO 1,6-Hexanedioll is also used as raw material to make reactive diluent for epoxy resin.
The chemical structure of HDO 1,6-Hexanediol containing terminally located hydroxyl groups makes it highly reactive and useful for the production of various derivatives.
HDO 1,6-Hexanediol is also used as raw material for UV curing material, expanding its market share as an environmentally friendly coating material that does not use solvents.
HDO 1,6-Hexanediol is a building block for saturated polyesters, and polyurethane acrylic esters of 1,6-Hexanediol are used as reactive diluents for UV coatings.
HDO 1,6-Hexanediol is used in polyesters for solvent-based paints, baking enamels for automotive coatings, tin and coil coatings, and for general applications.
HDO 1,6-Hexanediol is preferably used in two component paints, plastic coatings and repair coatings.
HDO 1,6-Hexanediol is suitable for polyester plasticizers and for polyurethanes in soft segments.
HDO 1,6-Hexanediol shows an optimum balance of flexibility and toughness (excellent flexibility with sufficient hardness) in polyesters and polyurethane.
HDO 1,6-Hexanediol is used as an intermediate in polymer synthesis (nylon, polyester production).
Its main application area is the manufacture of polyurethane to produce many products in the field of UV coating active monomer (HDDA), Polycarbonatediol (PCD) and Polyesters.
HDO 1,6-Hexanediol is also used in gasoline refining and pharmaceutical manufacturing.
HDO 1,6-Hexanediol has a six-carbon straight-chain structure with hydroxyl groups attached to the first and sixth carbon atoms.
It is a white, crystalline solid at room temperature and is highly soluble in water and various organic solvents.
Melting point: 38-42 °C (lit.)
Boiling point: 250 °C (lit.)
Density: 0.96
vapor pressure: 0.53 mm Hg ( 20 °C)
refractive index: 1.457
Flash point: 215 °F
storage temp.: Store below +30°C.
solubility: H2O: 0.1 g/mL, clear, colorless
form: Waxy Flakes
pka: 14.87±0.10(Predicted)
color: White
PH: 7.6 (900g/l, H2O, 20℃)
explosive limit: 6.6-16%(V)
Water Solubility: 500 g/L
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1
Merck: 14,4690
BRN: 1633461
InChIKey: XXMIOPMDWAUFGU-UHFFFAOYSA-N
LogP: 0 at 25℃
HDO 1,6-Hexanediol is commonly used in polycarbonate diols, reactive diluents, saturated and unsaturated polyester resins, hot melt adhesives, and in the production of polyester polyols.
It is used as a chain extender in polyurethane production, creating products with mechanical strength and a high resistance to hydrolysis.
HDO 1,6-Hexanediol is a monomer for Acrylic & Methacrylic Oligomers.
HDO 1,6-Hexanediol is a chemical intermediate for polymeric plasticizers, surfactants, and other specialty chemicals.
HDO is widely used as a building block in the manufacture of polyurethanes, especially for flexible and rigid foams, elastomers, coatings, adhesives, and sealants.
HDO 1,6-Hexanediol's a key ingredient in the synthesis of polyester and polyamide resins, which are used in various applications, including automotive coatings and fiber production.
In plastics manufacturing, HDO 1,6-Hexanediol is used to produce plasticizers that improve flexibility and durability.
HDO 1,6-Hexanediol is commonly employed in UV-curable coatings and adhesives, which are important in electronics, automotive, and construction materials due to their fast curing times and strong adhesion properties.
HDO 1,6-Hexanediol is involved in producing spandex, an elastic fiber used in clothing and sportswear, due to its ability to enhance stretch and durability.
Direct contact with HDO 1,6-Hexanediol may cause skin and eye irritation, and inhalation of vapors can irritate the respiratory system.
HDO 1,6-Hexanediol is not particularly toxic to aquatic life but should still be handled responsibly to avoid spills and contamination of water sources.
HDO 1,6-Hexanediol is produced industrially by the catalytic hydrogenation of adipic acid or of its esters.
Mixtures of dicarboxylic acids and hydroxycarboxylic acids with C6 components formed in other processes (e.g., in cyclohexane oxidation) are also used.
Esterifification of "distillation heavies" with lower alcohols is often carried out before hydrogenation.
The acids are hydrogenated continuously at 170-240 ℃ and at 15.0-30.0 MPa on a suitable catalyst either in a trickle-flflow (downflflow) or a bubble-flflow (upflflow) fifixed-bed reactor.
The reactor temperature is controlled by circulating part of the reactor discharge.
The hydrogen required for the hydrogenation is fed together with the recycle gas through the recycle gas compressor to the reactor.
Side products of the synthesis are alcohols, ethers, diols, and esters.
Pure 1,6-hexanediol is obtained by fractional distillation of the crude reactor discharge.
For the hydrogenation of dicarboxylic acids, catalysts containing cobalt, copper, or manganese are suitable.
For the hydrogenation of esters, catalysts such as copper chromite or copper with added zinc and barium are used as "full catalysts" or on inert carriers.
Ruthenium, platinum, or palladium on inert supports can also be used. Gas-phase hydrogenation of esters of adipic or 6-hydroxyhexanoic acid can be carried out at 1-7 MPa.
Both acids and esters also may be hydrogenated using suspended catalysts.
Oligomeric esters of the product diol and adipic acid can also be hydrogenated.
HDO 1,6-Hexanediol in the form of flflakes or as a solidifified melt is stored and shipped in barrels.
HDO 1,6-Hexanediol is transported as a melt in stainless steel containers, tank trucks, or tank cars.
Term used for colorants, dyes, or pigments; includes colorants for drugs, textiles, personal care products (cosmetics, tatoo inks, hair dye), food colorants, and inks for printing; modifiers included when application is known.
General construction (as opposed to those things labeled building_construction).
HDO 1,6-Hexanediol, or related to the manufacturing of drugs; modified by veterinary, animal, or pet if indicated by source.
Includes antifoaming agents, coagulating agents, dispersion agents, emulsifiers, flotation agents, foaming agents, viscosity adjustors, etc.
Includes food packaging, paper plates, cutlery, small appliances such as roasters, etc.; does not include facilities that manufacture food.
Plastic products, industry for plastics, manufacturing of plastics, plastic additives (modifiers included when known).
Leather products, and products/chemicals used in the process of tanning and dressing leather.
Uses:
IRelated to the manufcturing of pulp or paper products, or paper products in general.
Textiles used for clothing or furniture upholstery, processes related to textiles.
Wood used as a building material, wood preservatives.
Term used for colorants, dyes, or pigments; includes colorants for drugs, textiles, personal care products (cosmetics, tatoo inks, hair dye), food colorants, and inks for printing; modifiers included when application is known.
Generic lubricants, lubricants for engines, brake fluids, oils, etc (does not include personal care lubricants).
Chemical General term used only when the only information known from the source is 'chemical,' typically related to manufacturing of chemicals, or laboratory chemicals.
HDO 1,6-Hexanediol is widely utilized in the manufacture of polyesterols such as sebacates, azelates, and adipates.
These compounds are resistant to hydrolysis and have low glass transition temperature as well as high mechanical levels.
HDO 1,6-Hexanediol is used as an ingredient in the preparation of a wide range of tailor-made products for numerous specialty and standard applications.
HDO 1,6-Hexanediol is utilized as an ingredient in the manufacture of the bifunctional hexanediol diacrylate which is a monomer that is normally used in conjunction with other acrylic monomers as a reactive diluent for decorative coatings and printing inks.
Urethanes and co-terephthalates that are based on HDO 1,6-Hexanediol provide faster better tack properties and crystallization.
Due to its low glass transition property, HDO 1,6-Hexanediol offers high flexibility as well as excellent adhesive properties.
HDO 1,6-Hexanediol is incorporated into the production of other compounds used in polymeric thickeners, sizing agents, plasticizers for polyvinyl chloride, pesticides, and surfactants dyestuffs as a flexible building block.
HDO 1,6-Hexanediol is used as a monomer in producing polyurethanes, which are widely applied in flexible foams (such as those used in furniture and mattresses) and rigid foams (such as insulation materials).
HDO 1,6-Hexanediol enhances the elasticity and resilience of polyurethane elastomers used in automotive components, gaskets, and rollers.
HDO 1,6-Hexanediol contributes to the production of coatings, adhesives, and sealants in the construction and electronics industries.
It provides properties like durability, resistance to chemicals, and adhesion.
HDO 1,6-Hexanediol is a key ingredient in polyester and polyamide resins used in high-performance coatings.
These resins provide protective, durable coatings for automotive and industrial applications, including corrosion-resistant coatings.
HDO 1,6-Hexanediol is used in polyester and polyamide-based fibers, films, and packaging materials due to its ability to enhance flexibility, durability, and resistance to heat and chemicals.
HDO 1,6-Hexanediol acts as a plasticizer, increasing flexibility and reducing brittleness in polyvinyl chloride (PVC) and other plastics, making them more suitable for various applications, including flooring, cables, and tubing.
HDO 1,6-Hexanediol is used in UV-curable coatings and adhesives that cure rapidly under ultraviolet light, making it ideal for precision applications in electronics and optics.
These coatings provide strong adhesion, clarity, and fast processing.
UV-curable coatings are also widely used in automotive and construction for durable, scratch-resistant, and chemically resistant finishes.
HDO 1,6-Hexanediol is used in the production of spandex, an elastic fiber that provides stretchability and durability in athletic wear, swimwear, and other flexible garments.
HDO 1,6-Hexanediol can act as a reactive diluent in epoxy resins, enhancing properties such as flexibility and impact resistance in coatings, adhesives, and sealants.
HDO 1,6-Hexanediol is sometimes used in small quantities in cosmetics and personal care products due to its moisturizing and viscosity-regulating properties.
HDO 1,6-Hexanediol has applications in biomedical and pharmaceutical fields, such as in controlled drug release systems or biodegradable polymers, due to its safety profile and biocompatibility.
HDO 1,6-Hexanediol can be used for a variety of applications such as:
HDO 1,6-Hexanediol a structure-directing agent for the synthesis of ZSM-5 zeolite
HDO 1,6-Hexanediol a solvent for titanium tetraisopropoxide to form titanium oxide (TiO2) nanocrystals a phase change material in combination with lauric acid for thermal energy storage applications.
HDO 1,6-Hexanediol is a no-irritating to the skin. However, it can be irritative to the respiratory tract and mucous membrane.
HDO 1,6-Hexanediol vapours or dust cause irritation to the eye. Severe eye exposure may cause conjunctivitis, iritis, and diffuse corneal opacity.
Safety Profile:
HDO 1,6-Hexanediol is used in polymer synthesis such as polyester, polyurethane and nylon.
It is used as an intermediate to adhesives, acrylics and dyestuffs.
Further, it is employed in gasoline refining and pharmaceutical production.
Direct contact with HDO 1,6-Hexanediol can cause skin irritation, leading to redness, itching, and in severe cases, chemical burns.
Prolonged exposure can worsen skin sensitivity and increase the risk of dermatitis.
HDO 1,6-Hexanediol is irritating to the eyes and may cause redness, pain, and blurred vision upon contact.
Eye protection is advised when handling HDO to prevent accidental exposure.
Inhalation of HDO vapors or mists can irritate the respiratory system, leading to coughing, sore throat, and discomfort.
In confined or poorly ventilated spaces, inhaling high concentrations may cause more severe respiratory distress.
While not common, exposure to high concentrations of HDO fumes or vapors can potentially affect the central nervous system, causing dizziness, drowsiness, or headaches.
Working in well-ventilated areas is important to avoid such effects.
