HENEICOSYLIC ACID

HENEICOSYLIC ACID = HENEICOSANOIC ACID

CAS Number: 2363-71-5
EC Number: 219-113-3
MDL number: MFCD00002805
Linear Formula: CH3(CH2)19COOH
Molecular FormulaC21H42O2

Heneicosylic Acid belongs to the class of organic compounds known as long-chain fatty acids. 
These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
Heneicosylic acid, or heneicosanoic acid, is a 21-carbon long-chain saturated fatty acid with the chemical formula CH3(CH2)19COOH. 
Heneicosylic Acid, also known as N-heneicosanoate or 21:0,is a long-chain fatty acid that is henicosane in which one of the methyl groups has been oxidised to give the corresponding carboxylic acid. 

Heneicosylic Acid is a straight-chain saturated fatty acid and a long-chain fatty acid. 
Heneicosylic Acid is a conjugate acid of a henicosanoate. 
Heneicosylic Acid belongs to the class of organic compounds known as long-chain fatty acids. 
Heneicosylic Acid is a very hydrophobic molecule, practically insoluble in water, and relatively neutral. 
Heneicosylic Acid, also known as N-heneicosanoate or 21:0, belongs to the class of organic compounds known as long-chain fatty acids.

Heneicosylic Acid is a very long-chain saturated fatty acid found in plants and animals, including human milk fat.
Heneicosylic Acid is unusual in many biological systems and is therefore often useful as an internal standard or biomarker. 
Heneicosylic Acid is found in small amounts in mammalian milk and is present in the articular cartilage boundary lubricant and red blood cell fatty acid. 
Heneicosylic Acid is a long-chain saturated fatty acid which is found in plants and animals

Long chain saturated fatty acid. 
p53 inhibitor. 
Inhibits dsDNA binding activity of p53. 
Energy source and metabolite in vivo. 
Orally active.

Heneicosanoic acid (HEA) is a fatty acid found in human milk fat. 
HEA is also a part of the phospholipids of the articular cartilage boundary lubricant. 
HEA is a constituent of red blood cell fatty acids.

USES and APPLICATIONS of HENEICOSYLIC ACID:
-Heneicosylic Acid has shown relevance in the production of foams, paints, and related viscous materials.
-Heneicosylic Acid is a long chain fatty acid used by S.epidermidis for lipopeptide production. 
-In addition, Heneicosylic Acid can be used as an analytical standard. 
-Heneicosylic Acid is also present in small amounts in various microorganisms and can aid in their identification by the comparison of their lipid profiles. 
-Heneicosylic Acid, along with other long chain fatty acids, shows significant inhibitory effects towards human p53 DNA binding domain.

ALTERNATIVE PARENTS of HENEICOSYLIC ACID:    
-Straight chain fatty acids 
-Monocarboxylic acids and derivatives 
-Carboxylic acids 
-Organic oxides 
-Hydrocarbon derivatives 
-Carbonyl compounds 

SUBSTITUENTS of HENEICOSYLIC ACID:    
-Long-chain fatty acid
-Straight chain fatty acid
-Monocarboxylic acid or derivatives
-Carboxylic acid
-Carboxylic acid derivative
-Organic oxygen compound
-Organic oxide
-Hydrocarbon derivative
-Organooxygen compound
-Carbonyl group
-Aliphatic acyclic compound

PHYSICAL and CHEMICAL PROPERTIES of HENEICOSYLIC ACID:
Molecular Weight: 326.56
Appearance Form: solid
Colour: colourless
Odour: No data available
Odour Threshold: No data available
pH No data available
Melting point/freezing point
Melting point/range: 74 - 75 °C - lit.

Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapour pressure: No data available
Vapour density: No data available

Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Auto-ignition temperature: No data available
Decomposition temperature: No data available
Viscosity: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available

Appearance: Powder
Physical State: Solid
Solubility: Soluble in chloroform (25 mg/ml).
Storage: Store at 4° C
Melting Point: 74-75° C (lit.)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 384.30 °C. @ 760.00 mm Hg (est)
Flash Point: 344.00 °F. TCC ( 173.10 °C. ) (est)

logP (o/w): 9.810 (est)
Density: 0.9±0.1 g/cm3
Boiling Point: 384.3±5.0 °C at 760 mmHg
Melting Point: 74-75 °C(lit.)
Molecular Formula: C21H42O2
Molecular Weight: 326.557
Flash Point: 173.1±12.5 °C

Exact Mass: 326.318481
PSA: 37.30000
LogP: 9.81
Vapour Pressure: 0.0±0.9 mmHg at 25°C
Index of Refraction: 1.458
Storage condition: 2-8°C

ΔfG°: -139.80 kJ/mol    
ΔfH°gas: -741.58 kJ/mol    
ΔfusH°: 55.83 kJ/mol    
ΔvapH°: 85.77 kJ/mol    
logPoct/wat: 7.50        
Pc: 1054.83 kPa    
Tboil: 825.93 K    
Tc: 1011.18 K    
Tfus: 347.65 ± 2.00 K    
Vc: 1.24 m3/kg-mol

FIRST AID MEASURES of HENEICOSYLIC ACID:
-Description of first aid measures
*If inhaled:
If breathed in, move person into fresh air. 
If not breathing, give artificial respiration.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person. 
Rinse mouth with water.
-Most important symptoms and effects, both acute and delayed:
-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of HENEICOSYLIC ACID:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel. 
Keep in suitable, closed containers for disposal.

FIREFIGHTING MEASURES of HENEICOSYLIC ACID:
-Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
-Further information:
No data available

EXPOSURE CONTROLS/PERSONAL PROTECTION of HENEICOSYLIC ACID:
-Control parameters:
Components with workplace control parameters:
-Exposure controls:
*Appropriate engineering controls:
General industrial hygiene practice.
*Personal protective equipment:

**Eye/face protection:
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

**Skin protection:
Handle with gloves. 
Gloves must be inspected prior to use. 
Wash and dry hands.

**Respiratory protection:
Respiratory protection is not required. 
Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. 
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
*Control of environmental exposure
No special environmental precautions required.

HANDLING AND STORAGE of HENEICOSYLIC ACID:
-Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place. 
Store in cool place.
Recommended storage temperature 2 - 8 °C.

STABILITY and REACTIVITY of HENEICOSYLIC ACID:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

SYNONYMS:
Heneicosylic acid
n-Heneicosanoic acid
Heneicosansaeure    
Heneicosylic acid    
N-Heneicosanoic acid    
N-Heneicosylic acid    
N-Henicosanoic acid    
Heneicosylate    
N-Heneicosanoate    
N-Heneicosylate    
N-Henicosanoate    
Heneicosanoate    
Heneicosanate    
Heneicosanic acid    
Henicosanoate    
Henicosanoic acid    
Heneicosanoic acid