CAS NO:659-40-5
EC NO:211-533-5
HEXAMIDINE DIISETHIONATE is classified as :
Antifoaming
Emollient
Preservative
Skin conditioning
Classification: Regulated , Conservative
Restriction in Europe: V/47
The maximum authorized concentration in ready-to-use cosmetic preparations is 0.1%.
Hexamidine Diisethionates functions (INCI)
Anti- dandruff: Helps fight dandruff
Anti-foaming: Suppresses foam during manufacturing / reduces foaming in liquid finished products
Antimicrobial: Helps slow the growth of microorganisms on the skin and opposes the development of microbes
Emollient: Softens and softens the skin
Preservative: Inhibits the development of micro-organisms in cosmetic products.
Skin conditioning agent: Keeps the skin in good condition
Cosmetic Uses:
antifoaming agents
preservatives
skin conditioning
skin conditioning - emollient
Chemical Properties
White or slightly yellow powder, hygroscopic
Uses
Hexamidine Diisethionate is an anti-microbial and preservative targeting fungi and yeast.
Hexamidine Diisethionate may also have some emollient capacities.
Uses
Hexamidine Diisethionate is a preservative in topical preparations and also in skin health and personal care products.
Uses
Preservative in cosmetics.
Hexamidine Diisethionate is a white, water-soluble powder. This antimicrobial, cationic substance has a broad spectrum of activity against bacteria, fungi and yeasts. In addition, dandruff is limited by the increase in the price of the head and the paid monthly amount of oiliness. With its use as a preservative for cosmetics and as an antiseptic agent in elaborate skins, hair and deodorants.
Hexamidine diisethionate has been used in the personal care industry and in a number of over-the-counter (OTC) drug products as an antimicrobial agent.
Hexamidine diisethionate was shown, that hexamidine diisethionate plays a beneficial role in skin homoeostasis.
Cosing functions
Antifoaming
Emollient
Preservative
Skin Conditioning Agent
What Is It?
In cosmetics and personal-care products, Hexamidine and Hexamidine Diisethionate function as a preservatives and are used in the formulation of hair, nail, and skin-care products, as well as eye makeup and baby products.
Why is it used in cosmetics and personal care products?
Hexamidine Diisethionate helps cleanse the skin or prevent odor by destroying or inhibiting the growth of microorganisms.
Scientific Facts:
Hexamidine Diisethionate is an organic salt of Hexamidine. Hexamidine is soluble in water and insoluble in organic solvents. These ingredients function as preservatives, which help cleanse the skin or prevent odor by inhibiting the growth of or destroying microorganisms, such as bacteria, fungi and yeast.
Hexamidine diisethionate is widely used in cosmetics industry, as a very effective preservative, skin and hair sterilizer, which has a good anti-acne, oil control, anti-stimulation, anti-dandruff effect.
It can be used to care for acne prone oily skin, lipid skin, scalp care (pityriasis scalp or dandruff condition) and wet tissue, hand soap products.
Hexamidine diisethionate 659-40-5 is an anti-microbial and inhibitory targeting fungi and yeast.
Hexamidine diisethionate may also have some emollient capacity and is a cosmetic preservative.
Hexamidine Diisethionate is suitable for cosmetic additive and sanitary products such as emulsion, mask, gel, water, alcohol solution, foaming agent, spray, etc.
1.Inhibiting microorganisms (preservatives).
A separate study is recommended for each cosmetic formula.
2. Skin and hair sterilization agent, care for oily and acne-prone skin.
Hexamidine diisethionate has antimicrobial activity on acne-specific strains such as Lactobacillus, and acne propionate can inhibit lipase activity.
Hexamidine diisethionate has an indirect anti-stimulation effect (slow hydrolysis of sebaceous gland triglycerides); anti-dandruff effect (egg-like ringworm fungus effect); and deodorant products.
Product Introduction:
Hexamidine diisethionate is a broad-spectrum, high-efficiency and water-soluble cationic antimicrobial agent for bacteria, molds and yeasts. Free of any form of formaldehyde, excellent to skin and mucous membrane, has a very good safety factor.
Hexamidine diisethionate can be safely used for people of all ages.
Product Feature:
Excellent Antibacterial Properties:
Hexamidine diisethionate has strong inhibition and good killing effect on gram-positive bacteria, gram-negative bacteria, fungi and yeast.
Product Application:
Widely used in cosmetics industry, as a multi-effect preservative, skin and hair sterilizer, which has a good anti-acne, oil control, anti-stimulation, anti-dandruff effect.
Hexamidine diisethionate can be used to care for acne prone oily skin, lipid skin, scalp care (pityriasis scalp or dandruff status) and wet tissue, hand soap products.
Hexamidine diisethionate is a hydrosoluble cationic preservative powder that can be used for the preservation of all personal care products.
Hexamidine diisethionate is very effective against a wide spectrum of microorganism including bacteria, fungi and yeasts.
Hexamidine diisethionate is recommended to be used in combination with other preservative with enhanced bactericidal properties.
Hexamidine diisethionate may be used widely in rinse off and leave on application.
Hexamidine diisethionate may be used in those products with not containing anionic surfactant such as wet wipes, moisturisers, conditioners and emollients.
FUNCTION:
1) Care of acne-prone oily skin;
2) Care of spilled skin;
3) Care of the scalp (scalp pityriasis or dandruff);
4) Deodorant products
Hexamidine Diisethionate is a hydrosoluble antimicrobial cationic substance with a wide spectrum of activity against bacteria, fungi and yeasts. Hexamidine may be used as a polyvalent preservative, as well as a cutaneous aseptizer, more and more used by the cosmetic industry.
Hexamidine Diisethionate are Widely used in cosmetics industry, as a multi-effect preservative, skin and hair sterilizer, which has a good anti-acne, oil control, anti-stimulation, anti-dandruff effect.
Hexamidine Diisethionate can be used to care for acne prone oily skin, lipid skin, scalp care (pityriasis scalp or dandruff status) and wet tissue, hand soap products.
Hexamidine Diisethionate Function and Application
Inhibiting microorganisms (preservatives).
A separate study is recommended for each cosmetic formula.
Skin and hair sterilization agent, care oily and acne prone to skin.
Hexamidine Diisethionate has antimicrobial activity on acne specific strains such as Lactobacillus, and it can inhibit the activity of the lipase of the acne propionate.
Hexamidine Diisethionate has indirect anti-stimulation effect (slow hydrolysis of sebaceous gland triglyceride) ; anti-dandruff effect (the effect of egg-like ringworm fungus); and can be used in deodorant products.
Cosmetic Functions.
Preservative;
Antifoaming;
Emollient;
Skin conditioning;
Scientific Evidence.
In cosmetics and personal-care products, Hexamidine and Hexamidine Diisethionate function as a preservatives and are used in the formulation of hair, nail, and skin-care products, as well as eye makeup and baby products.
About this substance
Helpful information
Hexamidine Diisethionate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 to < 10 tonnes per annum.
Hexamidine Diisethionate is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
Hexamidine Diisethionate is used in the following products: cosmetics and personal care products.
Other release to the environment of Hexamidine Diisethionate is likely to occur from: indoor use as processing aid.
Article service life
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.
Widespread uses by professional workers
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the types of manufacture using this substance. Other release to the environment of this substance is likely to occur from: indoor use as processing aid.
Formulation or re-packing
Hexamidine Diisethionate is used in the following products: cosmetics and personal care products.
Release to the environment of Hexamidine Diisethionate can occur from industrial use: formulation of mixtures.
Uses at industrial sites
Hexamidine Diisethionate is used in the following products: cosmetics and personal care products.
ECHA has no public registered data on the types of manufacture using this substance.
Release to the environment of Hexamidine Diisethionate can occur from industrial use: in processing aids at industrial sites.
Manufacture
Release to the environment of Hexamidine Diisethionate can occur from industrial use: manufacturing of the substance.
IUPAC names
2-hydroxyethanesulfonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboximidamide] (2:1)
2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] di-2-hydroxyethanesulphonate
4-[6-(4-carbamimidoylphenoxy)hexoxy]benzenecarboximidamide; 2-
4-[6-(4-carbamimidoylphenoxy)hexoxy]benzenecarboximidamide;2-hydroxyethanesulfonic acid
Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-[1,6- hexanediylbis(oxy)]bis[benzenecarboximidamide] (2:1)
SYNONYMS:
2-Hydroxyethanesulfonic acid - 4,4'-[1,6-hexanediylbis(oxy)]dibenzenecarboximidamide (2:1) [ACD/IUPAC Name]
2-Hydroxyethanesulfonic acid - 4,4'-[hexane-1,6-diylbis(oxy)]dibenzenecarboximidamide (2:1)
2-Hydroxyethansulfonsäure --4,4'-[1,6-hexandiylbis(oxy)]dibenzolcarboximidamid (2:1) [German] [ACD/IUPAC Name]
Acide 2-hydroxyéthanesulfonique - 4,4'-[1,6-hexanediylbis(oxy)]dibenzènecarboximidamide (2:1) [French] [ACD/IUPAC Name]
Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-[1,6-hexanediylbis(oxy)]bis[benzenecarboximidamide] (2:1) [ACD/Index Name]
Hexamidine diisethionate
2535 R. P.
2535 RP
2-Hydroxyethanesulfonic acid [ACD/IUPAC Name]
2-Hydroxyethanesulphonic acid, compound with 4,4'-(hexane-1,6-diylbis(oxy))bis(benzenecarboxamidine) (2:1)
2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
2-hydroxyethanesulphonic acid,compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
4,4'-(Hexane-1,6-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)
4-[6-(4-amidinophenoxy)hexoxy]benzamidine
4-[6-(4-amidinophenoxy)hexyloxy]benzenecarboxamidine, 2-hydroxyethanesulfonic cid, 2-hydroxyethanesulfonic acid
4-[6-(4-carbamimidoylphenoxy)hexoxy]benzamidine
4-[6-(4-carbamimidoylphenoxy)hexoxy]benzenecarboximidamide
4-[6-(4-CARBAMIMIDOYLPHENOXY)HEXOXY]BENZENECARBOXIMIDAMIDE, 2-HYDROXYETHANESULFONIC ACID