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Hexyldecanol is a fatty alcohol that serves as an emollient and helps improve the texture of cosmetic products.
Hexyldecanol is used to soften the skin, retain moisture, and facilitate the application of the product.
Hexyldecanol creates a pleasant "slip", making the products less sticky and helps evenly distribute active ingredients.
CAS Number: 2425-77-6
Molecular Formula: C16H34O
Molecular Weight: 242.44
EINECS Number: 219-370-1
Synonyms: 2-Hexyl-1-decanol, 2425-77-6, 2-Hexyldecan-1-ol, Hexyldecanol, 1-Decanol, 2-hexyl-, 2-Hexyldecanol, 2-Hexyldecyl Alcohol, Guerbitol 16, Isofol 16, Rilanit G 16, Jarcol I 16, NJCOL 160BR, NSC 2399, DTXSID1041265, NSC-2399, EINECS 219-370-1, JARCOL I-16, NJCOL 160, AI3-19964, 151Z7P1317, DTXCID9021265, EC 219-370-1, 2hexyldecanol, 2hexadecanol, Isohexa decanol, 2Hexyldecan1ol, 2Hexyldecanol1, Branched Alcohol, Isopalmitylalkohol, 2Hexadecyl alcohol, Isopalmitic alcohol, 1Decanol, 2hexyl, Hexyl1decanol, 2, ISOFOL 16 Alcohol, HEXYLDECANOL [INCI], DTXCID70254614, dtxsid00303482, Exxal 16, MFCD00060903, Guerbet Hexadecanol, Guerbet C16, NJCOL 160BRA, NSC2399, UNII-151Z7P1317, 2-octyl-1-octanol, SCHEMBL15863, 2-Hexyl-1-decanol, 97%, SCHEMBL2048001, SCHEMBL2453298, CHEMBL3560208, CHEBI:183266, Tox21_300799, AKOS015912415, CS-W012764, FH23823, NCGC00248173-01, NCGC00254703-01, AS-46984, BP-14094, SY034340, CAS-2425-77-6, H1461, NS00002307, 2-Hexyldecanol;2-Hexyldecyl alcohol;Exxal 16, F11131, Q27251672, 2-HEXYL-1-DECANOL;2-hexyl-1-decano;2-Hexyl-decan-1-ol;1-Decanol, 2-hexyl-;2-Hexyldecane-1-ol;2-Hexyldecyl Alcohol;Guerbet C16;Guerbet Hexadecanol
Hexyldecanol is a branched alcohol.
Hexyldecanol is one of the constituent of the essential oil, extracted from the roots of Adiantum flabellulatum.
Hexyldecanol is a long-chain glass forming monohydroxy alcohol and its dielectric relaxation at low temperature has been studied.
It also has a conditioning effect on the hair.
Thanks to its gentle influence, Hexyldecanol is suitable for sensitive skin and is used in moisturizers, serums, sunscreens, makeup, shampoos, and conditioners.
Hexyldecanol, also known as 2-hexyldecan-1-ol, is an organic substance belonging to the group of fatty alcohols.
Hexyldecanol is a colorless liquid with a slightly fruity odor that is insoluble in water but dissolves well in organic solvents.
The structural formula of hexyldecanol has the configuration C16H34O, which means that it has sixteen carbon atoms, thirty-four hydrogen atoms and one oxygen atom.
Hexyldecanol can be created from natural sources, not synthetic ones, which makes its application "greener".
Hexyldecanol is often used in industry as an ingredient in various products due to its properties.
The most common uses include its presence in cosmetic and personal skin and hair care products.
It is a popular ingredient in sunscreens, creams, shampoos, conditioners and make-up where it acts as a moisturizer, emollient or emollient.
Hexyldecanol is also used as a lubricant in industrial applications, including automotive and aerospace.
In the pharmaceutical industry, hexyl decanol is used in the manufacture of ointments, creams and other drugs for its ability to improve the binding and consistency of products.
In the food industry, it is occasionally used as a flavoring or food additive.
The safety and efficacy of hexyldecanol have been tested and approved by various regulatory authorities around the world, including the European Food Safety Authority (EFSA) and the U.S. Food and Drug Administration (FDA).
Hexyldecanol, also known as 2-Hexyl-1-decanol or 2-Hexyldecyl alcohol, is a high molecular weight, branched-chain fatty alcohol composed of a 16-carbon backbone with a hydroxyl (-OH) group on the first carbon atom.
Hexyldecanols structure is characterized by a linear decanol (C₁₀ alcohol) backbone with a hexyl (C₆) branch on the second carbon, giving it both hydrophobic and mildly hydrophilic properties, which makes it especially useful in emulsification and formulation chemistry.
It typically appears as a clear, colorless to slightly yellow liquid that is odorless or faintly fatty in smell, and it is known for being non-volatile, hydrophobic, and chemically stable under most conditions.
Because of its branched structure, hexyldecanol has a low melting point and remains liquid at room temperature, making it particularly suitable for use in cosmetic, personal care, and industrial formulations where smooth texture and spreadability are desired.
Hexyldecanol is widely used as an emollient, a substance that helps soften and smooth the skin by forming a protective layer that retains moisture.
It provides a rich, silky skin feel without being greasy or occlusive, and is often found in products like lotions, creams, sunscreens, serums, and hair conditioners.
Its excellent compatibility with a wide range of ingredients, including silicones, esters, and oils, allows formulators to create stable emulsions and aesthetically pleasing textures in products for both face and body.
A synthetic, non-drying fatty alcohol used as an emollient and skin-softening agent.
Hexyldecanol is aliphatic or straight-chain alcohol.
Hexyldecanol comes as a liquid.
The straight-chain alcohols depending upon chain length are more fat-soluble or fatty in nature.
Hexyldecanol, also known as 2-Octyldodecanol, is a versatile compound that is used in a wide range of beauty, wellness, and industrial products.
Hexyldecanol is a fatty alcohol that is derived from natural sources such as coconut oil, palm oil, and soybean oil.
Hexyldecanol can also be synthesized in the laboratory from petrochemicals.
Hexyldecanol has a mild, pleasant odor and is a colorless, oily liquid that is insoluble in water but soluble in alcohol, ether, and oils.
In terms of its chemical structure, hexyldecanol belongs to the family of long-chain alcohols with the formula C16H34O.
Hexyldecanol is composed of a straight-chain alcohol with a chain length of 10 carbon atoms and a branched alcohol with a chain length of 8 carbon atoms.
Hexyldecanol is commonly used in the cosmetic industry as an emollient, which helps to soften and soothe the skin.
Hexyldecanol is also used as a solvent and a fragrance ingredient in various personal care products such as lotions, creams, and perfumes.
Hexyldecanol is an essential ingredient in a wide range of cosmetics and personal care products.
Hexyldecanol's various properties make it a popular component in creams, lotions, balms, serums, and other beauty products.
Hexyldecanol provides a smooth, silky texture that enhances the overall user experience and improves the eectiveness of the active ingredients in the product.
In addition, hexyldecanol is a popular ingredient in natural and organic products, as it is derived from renewable sources and is biodegradable.
Melting point: -21 – -15 °C (lit.)
Boiling point: 193–197 °C/33 mmHg (lit.)
Density: 0.836 g/mL at 25 °C (lit.)
Vapor pressure: 0.4 Pa at 148.85 °C
Refractive index: n20/D 1.449 (lit.)
Flash point: 113 °C
Storage temp.: Refrigerator
Solubility: Benzene (Sparingly), Chloroform (Sparingly), Methanol (Slightly)
pKa: 15.08 ± 0.10 (Predicted)
Form: Oil
Color: Clear Colourless
InChIKey: XULHFMYCBKQGEE-UHFFFAOYSA-N
LogP: 6.66 at 20 °C
Hexyldecanol is used in industrial applications as a coalescing agent in paints and coatings, where it helps bind pigment particles together and improves the film-forming properties of latex-based systems.
Its chemical stability and resistance to oxidation make it useful in lubricant formulations and plastic additives, where long-term performance under stress is required.
From a toxicological standpoint, hexyldecanol is considered to have low acute toxicity, is generally non-irritating to the skin, and has been evaluated for safety by regulatory agencies such as the Cosmetic Ingredient Review (CIR) Expert Panel and European Chemicals Agency (ECHA).
Studies indicate that it does not sensitize the skin, is not mutagenic or carcinogenic, and is safe for use in rinse-off and leave-on applications at typical concentrations.
Hexyldecanol is a versatile, high-purity fatty alcohol that plays an important role in both consumer and industrial products due to its emollient properties, formulation flexibility, and safe toxicological profile.
Hexyldecanol bridges the gap between function and sensory performance, making it a favored ingredient in high-end cosmetics and performance-enhancing industrial formulations alike.
Hexyldecanol is a branched alcohol.
Hexyldecanol is one of the constituent of the essential oil, extracted from the roots of Adiantum abellulatum.
Hexyldecanol is a long-chain glass forming monohydroxy alcohol and its dielectric relaxation at low temperature has been studied.
Hexyldecanol is an essential ingredient in a wide range of cosmetics and personal care products.
Hexyldecanol's various properties make it a popular component in creams, lotions, balms, serums, and other beauty products.
Hexyldecanol provides a smooth, silky texture that enhances the overall user experience and improves the eectiveness of the active ingredients in the product.
Hexyldecanol is a fatty alcohol that is derived from natural sources such as coconut oil, palm oil, and soybean oil.
Hexyldecanol can also be synthesized in the laboratory from petrochemicals.
Hexyldecanol has a mild, pleasant odor and is a colorless, oily liquid that is insoluble in water but soluble in alcohol, ether, and oils.
In terms of its chemical structure, hexyldecanol belongs to the family of long-chain alcohols with the formula C16H34O.
Hexyldecanol is composed of a straight-chain alcohol with a chain length of 10 carbon atoms and a branched alcohol with a chain length of 8 carbon atoms.
Hexyldecanol's use in such products supports the growing trend towards sustainability and eco-friendliness.
Furthermore, hexyldecanol has been found to have moisturizing and emollient properties, which help to hydrate and soften the skin.
This makes Hexyldecanol a valuable ingredient in products designed for dry or sensitive skin types.
Additionally, hexyldecanol has been shown to have antioxidant properties, which can help to protect the skin from environmental stressors and premature aging
Uses Of Hexyldecanol:
Hexyldecanol may also be used as a chemical intermediate in the synthesis of esters, ethers, and surfactants, especially in the production of mild, non-ionic surfactants used in shampoos, facial cleansers, and baby washes.
These surfactants are prized for their low irritation potential and ability to form stable emulsions, which are crucial for blending oil and water phases in both personal care and industrial products.
As a solvent or carrier fluid, hexyldecanol is occasionally employed in specialized applications where low volatility, low toxicity, and compatibility with both polar and nonpolar compounds are required.
For example, it can dissolve active pharmaceutical ingredients or cosmetic actives and assist in their controlled delivery to the skin or surface.
Because it is often derived from natural fatty alcohols, hexyldecanol is increasingly used in eco-friendly and sustainable product lines, particularly those marketed as “green” or “plant-based.”
Its biodegradability and generally low environmental impact make it a suitable ingredient for brands seeking to comply with clean beauty standards, natural certifications, or EU REACH regulations.
In academic and industrial research, hexyldecanol may also be used as a model branched alcohol in studies involving surfactant behavior, emulsion stability, and formulation science, especially when investigating how structural modifications affect physical performance.
Hexyldecanol is also evaluated for its role in lipid-based delivery systems, such as nanoemulsions or lipid nanoparticles, in both cosmetics and pharmaceutical research.
A compound isolated from different parts of Lonicera japonica Thunb.
It is used in cosmetic and pharmaceutical preparations.
Hexyldecanol may be employed as an organic solvent to study the extraction of non-polar acidic drugs from human plasma by parallel artificial liquid membrane extraction (PALME).
Hexyldecanol along with any formulation when applied on the skin, imparts moisturization.
Hexyldecanol forms a film over the skin or hair surface, which is water-repellent.
Hexyldecanol does not allow moisture to escape plus it builds the moisture pool for the skin.
This can be considered an ideal environment for a speedy recovery of extremely dry skin. It is less viscous and so spreads more easily.
Hexyldecanol is used as a solvent in skincare, body care, and toiletries.
Hexyldecanol along with any formulation when applied on the skin, imparts moisturization.
Hexyldecanol forms a lm over the skin or hair surface, which is water-repellent.
Hexyldecanol does not allow moisture to escape plus it builds the moisture pool for the skin.
This can be considered an ideal environment for a speedy recovery of extremely dry skin.
Hexyldecanol is less viscous and so spreads more easily.
Hexyldecanol is used as a solvent in skincare, body care, and toiletries.
One of the primary and most common uses of hexyldecanol is in the cosmetics and personal care industry, where it serves as a multifunctional emollient in products designed to moisturize, protect, and soften the skin.
As an emollient, hexyldecanol works by forming a smooth, semi-occlusive layer on the surface of the skin, which helps to trap moisture and reduce transepidermal water loss (TEWL), leaving the skin feeling soft, hydrated, and nourished without a greasy or oily residue.
It is especially favored for its lightweight and silky texture, which contributes to the pleasant sensory profile of creams, lotions, balms, body butters, facial serums, eye creams, and anti-aging products.
Because of its low irritation potential, hexyldecanol is used in formulations for sensitive skin, baby care, and dermatologically tested products, and it is often included in hypoallergenic and fragrance-free skin care items.
In hair care products like conditioners, leave-in treatments, and styling serums, hexyldecanol helps to smooth the hair shaft, reduce frizz, improve manageability, and add a soft sheen without weighing the hair down or leaving residue.
Furthermore, in decorative cosmetics such as foundations, primers, lipsticks, eyeshadows, and BB creams, hexyldecanol improves the spreadability and enhances the skin feel by helping pigments and powders blend evenly on the skin, giving a more uniform application and longer-lasting wear.
Hexyldecanol also functions as a solubilizer for active ingredients, fragrances, or UV filters in products such as sunscreens, self-tanners, and perfumed lotions, thereby enhancing both product efficacy and user experience.
Beyond the cosmetic field, hexyldecanol is also used in a variety of industrial applications, particularly due to its branched-chain structure, chemical stability, and low volatility.
In the paint and coatings industry, it acts as a coalescing agent, a component added to latex-based paints and waterborne coatings to assist in the formation of a continuous and smooth film as the paint dries.
By lowering the minimum film-forming temperature (MFFT), hexyldecanol helps coatings cure properly at lower temperatures, which is crucial for performance in architectural and protective coatings.
Hexyldecanol is also employed as a plasticizer and processing aid in the production of plastics and synthetic materials, where it contributes to the flexibility, softness, and durability of polymer-based systems.
In this role, it can enhance the flow characteristics of molten plastic, facilitate the mixing of additives, and improve the compatibility of polymers with other compounds.
In lubricants and hydraulic fluids, hexyldecanol can be used as a base fluid or additive that enhances lubricity, oxidation resistance, and thermal stability, making it suitable for high-performance applications such as automotive fluids, metalworking oils, and high-speed machinery.
Hexyldecanols branched molecular structure also allows it to function well under stress, resisting breakdown even under heat or pressure.
Safety Profile Of Hexyldecanol:
Hexyldecanol, like many fatty alcohols, generally exhibits low acute toxicity and is considered to be relatively safe for use in cosmetic and industrial applications when handled properly.
However, it may cause mild to moderate irritation upon direct contact with the skin or eyes, especially in its pure form or at high concentrations.
Prolonged or repeated skin exposure can sometimes lead to dryness, redness, or dermatitis, particularly in individuals with sensitive skin or pre-existing dermatological conditions.
Eye contact may result in temporary discomfort, redness, and watering, but serious damage is uncommon with typical accidental exposure.
Protective gloves and eye protection are recommended to minimize these risks, particularly in industrial or laboratory settings where concentrated forms are handled.
While hexyldecanol has a low volatility and does not readily form harmful vapors under normal temperature and pressure, inhalation of aerosols, mists, or vapors generated during heating, spraying, or industrial processes may cause respiratory tract irritation.
Symptoms can include coughing, throat discomfort, and in some cases, mild shortness of breath.
Adequate ventilation, use of respiratory protection where necessary, and controlling exposure levels are important safety measures to prevent inhalation hazards in occupational environments.
Available toxicological data indicate that hexyldecanol exhibits low systemic toxicity when ingested, inhaled, or absorbed through the skin, and it is not classified as a carcinogen, mutagen, or reproductive toxin by major regulatory bodies such as the European Chemicals Agency (ECHA) or the U.S. Environmental Protection Agency (EPA).
However, ingestion of large quantities can lead to gastrointestinal discomfort, including nausea, vomiting, or diarrhea, and should be avoided.
In occupational settings, repeated or chronic exposure should be monitored, even though serious long-term health effects have not been reported.
