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Hexylene Glycol (HG) as a surfactant helps to cleanse and moisturize the skin as well as thinning out the formulation to improve absorption, texture and allow other ingredients to work better.
Hexylene Glycol (HG) is a clear, colorless liquid with a characteristic odor.
Hexylene Glycol (HG) is famous for its excellent solvency among a wide variety of materials and is popular in skin care formulas due to its ability to improve the texture.
CAS Number: 107-41-5
Molecular Formula: C6H14O2
Molecular Weight: 118.17
EINECS Number: 203-489-0
Hexylene Glycol (HG) is used as a chemical intermediate, a selective solvent in petroleum refining, a component of hydraulic fluids, a solvent for inks, and as an additive for cement.
Industrial exposure is likely to be from direct contact or from inhalation, particularly if the material is heated.
Hexylene Glycol (HG) is a clear, hygroscopic liquid with a mild, sweet odor.
Hexylene Glycol (HG) is most often synthetically produced.
In cosmetics and personal care products, Hexylene Glycol (HG) is often used as a viscosity-decreasing agent.
Hexylene Glycol (HG) can help adjust the thickness or flow properties of a product to make it easier to apply or spread.
When used as directed and within recommended concentrations, Hexylene Glycol (HG) is generally considered safe for use in cosmetics and personal care products.
Hexylene Glycol (HG) has a low potential for skin irritation and is not known to be a skin sensitizer.
Hexylene Glycol (HG) is biodegradable, which means it can be broken down by natural processes over time.
This property can be advantageous in applications where environmental considerations are important.
Hexylene Glycol (HG)'s worth noting that while Hexylene Glycol (HG) is generally safe for use in cosmetics and personal care products, individuals with specific sensitivities or allergies may still experience reactions.
As with any chemical ingredient, it's a good practice to perform a patch test.
Hexylene Glycol (HG) is manufactured by the condensation of 2 molecules of acetone to produce diacetone alcohol, which is further hydrogenated to produce Hexylene Glycol (HG).
Hexylene Glycol (HG) is used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products at concentrations ranging from 0.1% – 25%.
Hexylene Glycol (HG) is a versatile solvent, which means it can dissolve a wide range of substances.
This property makes it useful in various applications where a liquid medium is needed to dissolve and carry other chemicals.
Hexylene Glycol (HG) has hygroscopic properties, meaning it can absorb and hold onto water molecules from its surroundings.
This can be beneficial in some formulations where moisture control is essential.
Hexylene Glycol (HG) has relatively low volatility, meaning it doesn't readily evaporate at room temperature.
This characteristic makes it useful in products where you want to control the rate of evaporation.
Hexylene Glycol (HG) is compatible with a wide range of other chemicals and ingredients, making it a valuable additive in many formulations.
Reactivity with Water No reaction; Reactivity with Common Materials: Can catch fire when in contact with porous materials such as wood, asbestos, cloth, soil, or rusty metals; Stability During Transport: Stable at ordinary temperatures, however when heated this material can decompose to nitrogen and ammonia gases.
The decomposition is not generally hazardous unless it occurs in confined spaces; Neutralizing Agents for Acids and Caustics: Flush with water and neutralize the resulting solution with calcium hypochlorite; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Hexylene Glycol (HG) is a diol organic compound with a chiral carbon atom.
Hexylene Glycol (HG), also known as 2-methyl-2,4-pentanediol, is a clear, colorless liquid with a mild odor.
Hexylene Glycol (HG) is a type of glycol, which is a chemical compound belonging to the alcohol family.
The appearance is colorless liquid with mild sweetness.
Hexylene Glycol (HG) is a colorless liquid at room temperature and can be Diacetone alcohol is hydrogenated.
Hexylene Glycol (HG) is miscible with water, soluble in ethanol, and soluble in most organic solvents.
Hexylene Glycol (HG), also known as 2-Methyl-2,4-pentanediol, is an organic compound that can be classified as a glycol.
Glycols are a class of alcohols that contain two hydroxyl groups, which can also be called a diols.
Hexylene Glycol (HG) has viscosity-reducing properties that allow it to thin out heavy, thick formulations and produce smooth spreadability.
Studies indicate it also exhibits antimicrobial properties.
In addition to skin care, Hexylene Glycol (HG) is used in other beauty products including hair care and makeup.
Hexylene Glycol (HG) also goes by its chemical compound name: 2-Methyl-2,4-pentanediol. As a raw material, it is a clear liquid.
Hexylene Glycol (HG) is often used in preservative blends that contain phenoxyethanol because it boosts the efficacy of this preservative, allowing lower amounts to be used, which reduces the risk skin will have a sensitised response.
Hexylene Glycol (HG), Ethoxydiglycol and Dipropylene Glycol are clear, practically colorless, liquids.
In cosmetics and personal care products, these ingredients are used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.
Hexylene Glycol (HG) is a clear liquid with a mild, sweet odour most commonly used in cosmetics and personal care products in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.
Hexylene Glycol (HG) (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.
Hexylene Glycol (HG) is fully miscible in water and has the chemical formula C6H14O2.
Hexylene Glycol (HG) is a compound that appears in a large number of products that are used commercially and industrially
Hexylene Glycol (HG) is prepared commercially by the catalytic hydrogenation of diacetone alcohol.
Melting point: -40 °C (lit.)
Boiling point: 197 °C (lit.)
Density: 0.925 g/mL at 25 °C (lit.)
vapor density: 4.1 (vs air)
vapor pressure: 0.02 mm Hg ( 20 °C)
refractive index: n20/D 1.427(lit.)
Flash point: 201 °F
storage temp.: Store below +30°C.
solubility: H2O: 1 M at 20 °C, clear, colorless
form: Slightly Viscous Liquid
pka: 15.10±0.29(Predicted)
color: Clear
PH: 6-8 (25℃, 1M in H2O)
Odor: Ammonia-like.
explosive limit 1-9.9%(V)
Water Solubility: soluble
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
LogP: 0 at 20℃
Hexylene Glycol (HG) helps to improve the texture and sensory feel of the formulation, functioning as a surfactant to cleanse and moisturize the skin, as an emulsifier and a viscosity-reducing agent to improve absorption and allow other ingredients to work better.
This property is valuable in products that require extended shelf life and protection against microbial contamination.
Hexylene Glycol (HG) can act as a stabilizer in certain formulations, helping to maintain the stability and integrity of the product over time.
This is important for products that may undergo changes in texture, color, or scent during storage.
While less common than other glycols like propylene glycol, Hexylene Glycol (HG) has been used as a food additive in some limited applications.
Hexylene Glycol (HG) may be used as a carrier or solvent for flavorings or colorings in the food and beverage industry.
Hexylene Glycol (HG) is sometimes used in laboratory settings as a solvent for various analytical techniques or for the preparation of samples.
While Hexylene Glycol (HG) is generally regarded as safe for use in cosmetics and personal care products, it is important to ensure that it is used within recommended concentrations and according to regulatory guidelines.
Hexylene Glycol (HG) is also crucial to handle it safely in industrial applications, as improper handling can lead to potential health and safety hazards.
Like other chemicals, Hexylene Glycol (HG) should be stored and handled according to the manufacturer's recommendations and safety data sheets (SDS).
This includes considerations for temperature, ventilation, and protective equipment when necessary.
Hexylene Glycol (HG) is often used in products as an odor-masking agent.
Hexylene Glycol (HG) mild odor can help cover or neutralize less pleasant odors in various formulations.
Hexylene Glycol (HG) can function as a humectant, which means it can help retain moisture in products and on the skin.
This property can be especially useful in cosmetic and skincare products to prevent drying and maintain skin hydration.
In some formulations, Hexylene Glycol (HG) can enhance the effectiveness of certain preservatives.
Preparation Of Hexylene Glycol (HG):
Using 2000 L of diacetone alcohol as a raw material to synthesize isohexanediol by hydrogenation reduction, the specific process steps are:
Step 1: Start the vacuum pump to vacuum the raw material metering tank.
When the vacuum is greater than -0.06Mpa, close the exhaust valve, open the feed valve, mix 2000 L of diacetone alcohol raw material and 200ppm sodium bicarbonate and pump it in Raw material metering tank.
Step 2: Open the vacuum valve on the reduction pot and pump the reduction pot to a vacuum of -0.1Mpa, then open the feed valve on the reduction pot, and add 2000 L of diacetone alcohol raw material and 200ppm sodium bicarbonate from the metering tank To the reduction pot, start the mixer to stir at the same time, add 95Kg of Raney nickel catalyst.
Step 3: Close the vacuum valve, open the nitrogen inlet valve, and inject nitrogen into the reduction pot.
After the pressure in the pot is increased to 0.6Mpa within 3 to 5 minutes, close the hydrogen inlet valve, open the vent valve, and reduce the pressure in the pot.
Reduce to normal pressure, repeat the above steps, re-inject nitrogen for replacement, and repeat this five times.
Step 4: When the nitrogen replacement in the third step is completed, close the vent valve, open the hydrogen inlet valve, and inject hydrogen into the reduction pot within 10-15 minutes.
When the pressure in the pot reaches 0.6Mpa, close the hydrogen inlet valve.
Open the vent valve, after the pressure in the pot drops to normal pressure, close the vent valve, repeat the above steps, re-inject hydrogen for replacement, and repeat this five times.
Step 5: After the hydrogen replacement, close the vent valve, open the hydrogen gas inlet valve, and inject hydrogen into the reduction pot.
Use hydrogen to make the pressure in the pot reach 1.9Mpa within 15 to 30 minutes, then close the hydrogen gas inlet valve and open it.
Jacketed steam valve, raise the temperature in the pot to 150°C, and adjust the stirring speed to 310r/min.
At this time, open the hydrogen gas inlet valve and control the temperature in the pot at 150°C.
On the basis of the stable temperature in the pot, Keep the hydrogen vapor pressure at 1.9Mpa for 4 hours, then close the hydrogen gas inlet valve and accurately record the current pressure in the boiler.
After 30 minutes, take a sample for gas chromatographic testing.
If the raw material content is less than 1% in the test result, it is qualified.
At this time, Close the jacketed steam valve and open the jacketed cooling water to reduce the temperature in the pot to normal temperature.
Then, open the vent valve to reduce the pressure in the pot to normal pressure.
Step 6: Stop the mixer and let it stand for 50 minutes, close the vent valve, open the nitrogen inlet valve, use nitrogen to increase the pressure in the pot to 0.6Mpa, close the nitrogen valve, open the empty valve, and slowly reduce the pressure in the pot to normal pressure , And then repeat this step 5 times.
Step 7: Open the nitrogen valve and the feed valve of the distillation pot at the same time.
Use 0.8Mpa nitrogen to send the qualified materials to the filter for filtration.
The filtered materials are pumped into the crude isohexanediol storage tank, and then pressed to the distillation Distillation is carried out in the kettle, and the filtered catalyst is recycled; the finished product from the rectification is isohexanediol.
After the raw material of 2000 L diacetone alcohol is hydrogenated and reduced to synthesize, 1865Kg of isohexanediol product is obtained with a purity of 99.5%.
The mass yield is 99%. After cooling, it is placed in the isohexanediol product storage tank.
The remaining by-products are mainly 29kg of 98% acetone, which can be sold as industrial acetone.
Uses Of Hexylene Glycol (HG):
Hexylene Glycol (HG) is used as a reagent in the synthesis of functionalized boronic esters.
Hexylene Glycol (HG) acts as a thickening agent in cosmetic products.
Hexylene Glycol (HG) is also employed as a blood volume expander.
Hexylene Glycol (HG) also acts as an emollient in shampoos and conditioners to provide hydration to the shafts.
Hexylene Glycol (HG) works to dissolve other ingredients present in a formulation and enhance the texture of the final product.
Hexylene Glycol (HG) is also employed as an antifreeze, and as a coupling agent for hydraulic fluids.
Hexylene Glycol (HG) is a moisturising, and setting, agent in the manufacture of textiles and can also be found in the cosmetics industry where it is a component of fragrances and bath, hair, and soap preparations.
Hexylene Glycol (HG) also has a role as a wetting agent in pesticide formulations and is a solvent in the preparation of dyes.
Hexylene Glycol (HG) is a clear, colorless liquid that is used in many personal care and cosmetic formulations.
Hexylene Glycol (HG) largely acts as a solvent, humectant, and viscosity agent. Decades of research have established Hexylene Glycol (HG) as a safe and effective ingredient.
Hexylene Glycol (HG) dissolves other ingredients in a product and enhances its stability and texture.
Hexylene Glycol (HG) also has a low viscosity that makes it easier to incorporate. The chemical formula of Hexylene Glycol (HG) is C6H14O2.
Hexylene Glycol (HG) is often used as a solvent and viscosity-decreasing agent in cosmetics and personal care products such as skin creams, lotions, and hair care products.
Hexylene Glycol (HG) helps in improving the texture and spreadability of these products.
Since it has low viscosity, it is a useful ingredient in products like foundations, primers, and concealers
Hexylene Glycol (HG) is used to control the flow properties of industrial products such as paints, coatings, cleansers, solvents, and hydraulic fluids.
Hexylene Glycol (HG) acts as a thickening agent in cosmetic products.
Hexylene Glycol (HG) is used in some pharmaceutical formulations as a solvent or as an excipient (a substance added to a drug to improve its formulation).
Hexylene Glycol (HG) can be found in industrial applications such as paints, coatings, and inks, where it serves as a solvent or a coalescing agent to help these products maintain their desired consistency.
Hexylene Glycol (HG) is used as a chemical intermediate in the synthesis of other chemicals.
In some cases, Hexylene Glycol (HG) is used in antifreeze and coolant formulations, although ethylene glycol and propylene glycol are more commonly used for this purpose.
Hexylene Glycol (HG) is considered relatively safe for use in cosmetics and personal care products when used within established concentration limits.
However, Hexylene Glycol (HG)'s essential to follow product labeling and guidelines to ensure safe use.
It serves as a coupling agent and an additive to hydraulic fluids, inks and cement.
Hexylene Glycol (HG) is also employed as a blood volume expander.
Hexylene Glycol (HG) is used as a solvent for cleaning and colorant products. In addition to this, it is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.
Hexylene Glycol (HG) is also used as a chemical intermediate, which accounts for approximately 20% of its consumption, and another 10% is used on oil and natural-gas fields where it is both a down hole lubricant, and a grinding and extraction aid.
Hexylene Glycol (HG) is primarily used in skin care to improve the sensory feel and texture of the products.
Hexylene Glycol (HG) also attracts and retains moisture on the surface of the skin, keeping it hydrated and nourished.
Hexylene Glycol (HG) is often found in products like toners and cleansers.
Hexylene Glycol (HG) is used as a viscosity agent and solvent to improve the texture and stability of formulations.
Hexylene Glycol (HG) is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.
Also Hexylene Glycol (HG) is used in the preparation of vinylboronates.
Hexylene Glycol (HG) is mainly used as a coupling agent and an additive to hydraulic fluids, inks and cement. Further, it is used as a solvent for cleaning and colorant products.
Hexylene Glycol (HG) is a potential substitute for glycol ethers.
Hexylene Glycol (HG) is an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexylene Glycol (HG) can also be used as a building block in chemical synthesis.
Hexylene Glycol (HG) is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.
Hexylene Glycol (HG) is used to control the flow properties of industrial products such as paints, coatings, cleansers, solvents, and hydraulic fluids.
Hexylene Glycol (HG) is a fine chemical product with a wide range of uses, which can be used in pesticides, biochemical engineering, photosensitive materials, synthetic fragrances and other fields.
Hexylene Glycol (HG) is a highly soluble high-grade organic solvent.
Hexylene Glycol (HG) can be used as an additive in the production of metal surface treatment agents for rust and oil removal.
Hexylene Glycol (HG) can also be used as a textile auxiliaries, as well as coatings and latex paints.
Hexylene Glycol (HG) can also be used in cosmetics, as a pesticide stabilizer, but also as a daily chemical moisturizer, flavor and fragrance raw materials, hydraulic oil, high-temperature lubricating oil, brake oil, dry cleaning agent, printing ink, pigment dispersant, wood preservative etc. As penetrant, emulsifier and antifreeze.
Safety Profile of Hexylene Glycol (HG):
Hexylene Glycol (HG) may cause skin and eye irritation upon direct contact.
Hexylene Glycol (HG) is advisable to use protective equipment, such as gloves and safety goggles, when handling the substance.
Inhalation of Hexylene Glycol (HG) vapors may cause respiratory irritation.
Adequate ventilation should be ensured in areas where the substance is used, and respiratory protection may be necessary in confined spaces.
Hexylene Glycol (HG) does not cause skin irritation and sensitization and is not known to be comedogenic.
Hexylene Glycol (HG) is generally considered safe for use in cosmetic products.
However, as with any ingredient, some individuals may have an allergic reaction or sensitivity to Hexylene Glycol (HG), so it is always recommended to patch test products before use.
Lastly, Hexylene Glycol (HG) is vegan and can be considered halal, but it is best to check with the supplier.
Synonyms Of Hexylene Glycol (HG):
Hexylene Glycol (HG)
2-METHYL-2,4-PENTANEDIOL
107-41-5
2-Methylpentane-2,4-diol
Diolane
Pinakon
2,4-Pentanediol, 2-methyl-
2,4-Dihydroxy-2-methylpentane
Isol
4-Methyl-2,4-pentanediol
1,1,3-Trimethyltrimethylenediol
Caswell No. 574
2-Methyl pentane-2,4-diol
2-Methyl-2,4-pentandiol
hexyleneglycol
HSDB 1126
UNII-KEH0A3F75J
(+-)-2-Methyl-2,4-pentanediol
NSC 8098
NSC-8098
EINECS 203-489-0
KEH0A3F75J
alpha,alpha,alpha'-Trimethyltrimethylene glycol
EPA Pesticide Chemical Code 068601
BRN 1098298
1,3-dimethyl-3-hydroxybutanol
CCRIS 9439
DTXSID5021885
CHEBI:62995
AI3-00919
Hexylene Glycol (HG) [NF]
1,3,3-trimethyl-1,3-propanediol
TRACID RUBINE 5BL
DTXCID101885
EC 203-489-0
1,1,3-trimethyl-1,3-propanediol
4-01-00-02565 (Beilstein Handbook Reference)
MFCD00004547
Hexylene Glycol (HG) (NF)
Hexylene Glycol (HG) (II)
Hexylene Glycol (HG) [II]
7-MethylAtracuriumDimesylate(MixtureofDiastereomers)
Hexylene Glycol (HG) (MART.)
Hexylene Glycol (HG) [MART.]
Hexylene Glycol (HG) (USP-RS)
Hexylene Glycol (HG) [USP-RS]
CAS-107-41-5
2-Methylpentan-2,4-diol
2-Methyl-pentane-2,4-diol
Hexilenglicol
Hexylne glycol
Hexylene Glycol (HG), 99%
R-(-)-2-METHYL-2,4-PENTANEDIOL
2methyl-2,4-pentanediol
2-Metyl-2,4-pentandiol
D06GOK
2-methyl-2-4-pentanediol
Hexylene Glycol (HG), >=99%
Hexylene Glycol (HG), 99.5%
SCHEMBL19379
Hexylene Glycol (HG) [MI]
1,3-Trimethyltrimethylenediol
2,4-pentanodiol, 2-metil-
Hexylene Glycol (HG) [HSDB]
Hexylene Glycol (HG) [INCI]
CHEMBL2104293
2- methylpentane- 2, 4- diol
NSC8098
(?)-2-Methyl-2,4-pentanediol
SVTBMSDMJJWYQN-UHFFFAOYSA-N
HMS3264E19
HY-B0903
2 - methylpentane - 2,4 - diol
Hexylene Glycol (HG), analytical standard
Tox21_201975
Tox21_302818
(+/-)-2-Methyl-2,4-pentanediol
s3588
AKOS015901459
CCG-213719
WLN: QY1 & 1XQ1 & 1
NCGC00249143-01
NCGC00256494-01
NCGC00259524-01
(+/-)-2,4-Dihydroxy-2-methyl pentane
AC-13749
AS-58339
Hexylene Glycol (HG), BioXtra, >=99% (GC)
(+/-)-2-Methyl-2,4-pentanediol, MPD
LS-101663
FT-0605050
FT-0605756
FT-0613069
Hexylene Glycol (HG), puriss., >=99.0% (GC)
M0384
(S)-(-)-2-METHYL-2,4-PENTANEDIOL
.alpha.,.alpha.'-Trimethyltrimethylene glycol
alpha,alpha,alpha'-trimethyltrimethyleneglycol
Hexylene Glycol (HG), BioUltra, >=99.0% (GC)
D04439
EN300-170052
AB01563179_01
J-640306
J-660006
Q2792203
W-108748
Z1255485267
Hexylene Glycol (HG), United States Pharmacopeia (USP) Reference Standard
