Hydratropic alcohol is a colorless liquid with a floral, rose-like scent.
Hydratropic alcohol has a characteristic rose-like odor and an initially slightly bitter taste, then sweet and reminiscent of peach.
Hydratropic alcohol, an aromatic alcohol with rose-like odor, is commonly used as a food flavoring and fragrance ingredient.
CAS Number: 60-12-8
EC Number: 200-456-2
Molecular Formula: C8H10O
Molecular Weight: 122.16
Synonyms: Phenethyl alcohol, Phenylethyl alcohol, 60-12-8, Benzeneethanol, Phenylethanol, Benzyl carbinol, Phenethanol, 2-Phenylethyl alcohol, 2-PHENYL-ETHANOL, beta-Phenylethanol, 2-Phenethyl alcohol, Benzylmethanol, 2-Phenylethan-1-Ol, Benzylcarbinol, Methanol, benzyl-, 2-Hydroxyethylbenzene, 1-Phenyl-2-ethanol, Ethanol, 2-phenyl-, FEMA No. 2858, 2-PEA, Benzenethanol, Phenethylalcohol, Phenyl ethyl alcohol, beta-PEA, beta-Phenylethyl alcohol, beta-Hydroxyethylbenzene, Caswell No. 655C, beta-Fenylethanol, FEMA Number 2858, 1321-27-3, beta-Fenethylalkohol, Phenethyl alcohol (natural), beta-Phenethyl alcohol, HSDB 5002, 2-Phenethanol, .beta.-Hydroxyethylbenzene, .beta.-Phenylethyl alcohol, Hydroxyethylbenzene, EINECS 200-456-2, UNII-ML9LGA7468, MFCD00002886, PhenethylAlcohol-d5, EPA Pesticide Chemical Code 001503, NSC 406252, NSC-406252, BRN 1905732, .beta.-Phenylethanol, ML9LGA7468, .beta.-PEA, DTXSID9026342, CHEBI:49000, AI3-00744, (2-Hydroxyethyl)benzene, .beta.-Phenethyl alcohol, Phenylethyl alcohol [USP], .beta.-(hydroxyethyl)benzene, DTXCID206342, EC 200-456-2, 4-06-00-03067 (Beilstein Handbook Reference), NSC406252, NCGC00166215-02, Phenylethyl alcohol (USP), Ethanol, phenyl-, PHENYLETHYL ALCOHOL (II), PHENYLETHYL ALCOHOL [II], PHENETHYL ALCOHOL (MART.), PHENETHYL ALCOHOL [MART.], Phenyl Ethanol(Natural), 2 Phenylethanol, PHENYLETHYL ALCOHOL (USP-RS), PHENYLETHYL ALCOHOL [USP-RS], beta-Fenylethanol [Czech], 2-phenyl ethanol, Carbinol, Benzyl, beta Phenylethanol, CAS-60-12-8, Alcohol, Phenethyl, beta-Fenethylalkohol [Czech], PEL, SMR000059156, PHENYLETHYL ALCOHOL (USP MONOGRAPH), PHENYLETHYL ALCOHOL [USP MONOGRAPH], Alcohol, Phenylethyl, benzene-ethanol, Mellol, phenyl-ethanol, Benzyl-Methanol, 2-PhenyIethanol, phenylethyl-alcohol, .beta.-Phenethanol, HY1, .beta.-Fenylethanol, b-Hydroxyethylbenzene, Benzyl ethyl alcohol, 2-phenyl-1-ethanol, Benzeneethanol, 9CI, 2-phenylethane-1-ol, betaphenylethyl alcohol, .beta.-Fenethylalkohol, 2-Phenylethanol, USP, METHANOL, BENZYL, A-PEA, beta -hydroxyethylbenzene, 2-Phenylethanol, 99%, .beta.-P.E.A., (BETA-PEA), Phenylethyl alcohol, USAN, bmse000659, Phenylethyl, beta- alcohol, 2-(2-Hydroxyethyl)benzene, SCHEMBL1838, WLN: Q2R, MLS001066349, MLS001336026, FEMA NUMBER 2858., PHENETHYL ALCOHOL [MI], Phenethyl alcohol, 8CI, BAN, CHEMBL448500, beta-(HYDROXYETHYL)BENZENE, PHENETHYL ALCOHOL [FCC], PHENYLETHYL, B- ALCOHOL, PHENETHYL ALCOHOL [INCI], BDBM85807, FEMA 2858, HMS2093H05, HMS2233H06, HMS3374P04, Pharmakon1600-01505398, PHENYLETHYL ALCOHOL [FHFI], PHENYLETHYL ALCOHOL [HSDB], PHENETHYL ALCOHOL [WHO-DD], BCP32115, CS-B1821, HY-B1290, NSC_6054, Tox21_113544, Tox21_201322, Tox21_303383, NSC759116, s3703, 2-Phenylethanol, >=99.0% (GC), AKOS000249688, Tox21_113544_1, CCG-213419, DB02192, NSC-759116, CAS_60-12-8, Phenethyl alcohol, >=99%, FCC, FG, NCGC00166215-01, NCGC00166215-03, NCGC00166215-05, NCGC00257347-01, NCGC00258874-01, AC-18484, SBI-0206858.P001, FT-0613332, FT-0673679, P0084, EN300-19347, C05853, D00192, D70868, Phenethyl alcohol, natural, >=99%, FCC, FG, AB00698274_05, A832606, Q209463, SR-01000763553, Phenylethyl alcohol, >=99%, FCC, FG, Phenylethyl Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material, 19601-20-8.
Hydratropic alcohol is an organic compound with the chemical formula C6H5CH2CH2OH.
Hydratropic alcohol is a colourless liquid with a pleasant floral odor.
Hydratropic alcohol occurs widely in nature, being found in a variety of essential oils.
Hydratropic alcohol is slightly soluble in water (2 ml per 100 ml of H2O), but miscible with most organic solvents.
The molecule of Hydratropic alcohol consists of a phenethyl group (C6H5CH2CH2−) attached to a hydroxyl group (−OH).
Hydratropic alcohol is an aromatic alcohol with a rose-like odour.
Hydratropic alcohol is a flavour and fragrance compound, and can be used as a preservative and anti-microbial agent. Hydratropic alcohol has antityrosinase and antimicrobial activities.
Because the Hydratropic alcohol has a good antibacterial efficiency, Hydratropic alcohol can be used in the ophthalmic solution.
Hydratropic alcohol is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
Hydratropic alcohol is also used as odor agents, air care products, cleaning and furnishing care products, laundry and dishwashing products, personal care products.
Hydratropic alcohol is the main flavor volatile of tomato and blue cheese.
Hydratropic alcohol is a clear, colorless liquid with an odor of rose oil.
Hydratropic alcohol has a burning taste that irritates and then anesthetizes mucous membranes.
Hydratropic alcohol is an aromatic alcohol that is used as a fragrance and an antimicrobial preservative in cosmetic formulations.
Hydratropic alcohol is active at pH 6 or less and is inactivated by nonionic detergents including polysorbate-80.
Hydratropic alcohol is also a widely used fragrance material that imparts a rose character to perfume compositions.
Hydratropic alcohol is an alcohol with a pleasant floral odor that occurs widely in nature.
Hydratropic alcohol is found in a variety of essential oils, including rose, carnation, hyacinth, Aleppo pine, orange blossom, ylang-ylang, geranium, neroli, and champaca.
Hydratropic alcohol is therefore a common ingredient in flavors and perfumery, particularly when the smell of rose is desired.
Hydratropic alcohol is responsible for honey-like aromas, a major aroma component of Muscat wine.
Hydratropic alcohol is used as an additive in cigarettes.
Hydratropic alcohol is also used as a preservative in soaps due to Hydratropic alcohol stability in basic conditions.
In biology Hydratropic alcohol is of interest due to its antimicrobial properties.
Hydratropic alcohol is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
Hydratropic alcohol is also used as odor agents, air care products, cleaning and furnishing care products, laundry and dishwashing products, personal care products.
Hydratropic alcohol is a primary alcohol and belongs to the class of compounds known as phenols.
The chemical formula for Hydratropic alcohol is C8H10O.
Hydratropic alcohol is a kind of edible spices, and naturally exists in neroli, rose oil, geranium oil and other oils, because Hydratropic alcohol has a soft, pleasant and persistent rose fragrance and is widely used in various kinds of flavors and cigarette flavor.
Hydratropic alcohol is dispensing rose scent, food additives, the main raw material for rose scent flavor, stable on alkali, which are widely used in soap fragrance, is essence blending all rose scent series of spices, because Hydratropic alcohol does not dissolve in water, Hydratropic alcohol is often used in the making up water, soap and orange flower, purple, etc.
Hydratropic alcohol is also used in the blending of flavor.
Hydratropic alcohol is an organic compound with the chemical formula C6H5CH2CH2OH.
Hydratropic alcohol is a colourless liquid with a pleasant floral odor.
Hydratropic alcohol is slightly soluble in water (2 ml per 100 ml of H2O), but miscible with most organic solvents.
The molecule of Hydratropic alcohol consists of a phenethyl group (C6H5CH2CH2−) attached to a hydroxyl group (−OH).
Hydratropic alcohol is metabolized to phenylacetic acid in mammals.
In humans, Hydratropic alcohol is excreted in urine as the conjugate phenylacetylglutamine.
Hydratropic alcohol is a clear, colorless liquid with a floral fragrance that is commonly used in cosmetics and personal care products as a preservative.
Hydratropic alcohol is chemical formula is C8H10O, and Hydratropic alcohol is naturally derived from plants such as rose and jasmine.
Hydratropic alcohol is effective against bacteria, fungi, and viruses, making Hydratropic alcohol a popular alternative to synthetic preservatives.
Hydratropic alcohol is soluble in both oil and water, which allows Hydratropic alcohol to be easily incorporated into a wide range of cosmetic formulations.
With Hydratropic alcohol natural origin and broad-spectrum antimicrobial properties, Hydratropic alcohol is a good choice for those looking for safe and effective preservatives.
Hydratropic alcohol is a primary alcohol that is ethanol substituted by a phenyl group at position 2.
Hydratropic alcohol has a role as a fragrance, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Aspergillus metabolite and a plant growth retardant.
Hydratropic alcohol is a primary alcohol and a member of benzenes.
Hydratropic alcohol, is a primary aromatic alcohol of high boiling point, having a characteristic rose-like odor.
Hydratropic alcohol presents organoleptic properties and impacts the quality of the wine, distilled beverages, and fermented foods.
Hydratropic alcohol shows its presence in fresh beer and is responsible for the rose-like odor of well-ripened cheese.
Hydratropic alcohol is commercially and industrially an important flavor and is a component of a variety of foodstuffs such as ice cream, gelatin, candy, pudding, chewing gum, and non-alcoholic beverages.
Hydratropic alcohol is an aromatic alcohol used as a flavoring agent in the cosmetic, perfume, and food industries.
Hydratropic alcohol occurs widely in nature, being found in a variety of essential oils.
Hydratropic alcohol is formed by yeasts during fermentation of alcohols either by decomposition of L-phenylalanine or metabolism of sugar substrates.
Hydratropic alcohol is also an autoantibiotic produced by the fungus Candida albicans.
Hydratropic alcohol is therefore a common ingredient in flavors and perfumery, particularly when the odor of rose is desired.
Hydratropic alcohol is used as an additive in cigarettes.
Hydratropic alcohol is also used as a preservative in soaps due to its stability in basic conditions.
Hydratropic alcohol is of interest due to its antimicrobial properties.
Hydratropic alcohol a colorless liquid used in small amounts as a so-called masking ingredient, meaning Hydratropic alcohol can hide the natural not-so-nice smell of other cosmetic ingredients.
Hydratropic alcohol has a nice rose-like scent and can be found in several essential oils such as rose, neroli or geranium.
Hydratropic alcohol also has some antimicrobial activity and can boost the performance of traditional preservatives.
Hydratropic alcohol is an aromatic alcohol that is used as a fragrance and an antimicrobial preservative in cosmetic formulations.
Hydratropic alcohol is metabolized to phenylacetic acid in mammals.
In humans, Hydratropic alcohol is excreted in urine as the conjugate phenylacetylglutamine.
The acute oral LD,s of Hydratropic alcohol to rats ranged from 2.5 to 3.1 ml/kg, and for mice and guinea pigs was 0.8 to 1.5 g/kg and 0.4 to 0.8 g/kg, respectively.
The dermal LD,s for rabbits and guinea pigs were 0.8 g/kg and 5 g/kg, respectively.
Hydratropic alcohol was slightly to moderately irritating to the skin of rabbits and guinea pigs and was not a guinea pig sensitizer.
Hydratropic alcohol, in concentrations of 1 % or greater, was irritating to the eyes of rabbits.
Hydratropic alcohol was neither an irritant nor a sensitizer in human studies.
Hydratropic alcohol was not mutagenic in the Ames test or in an Escherichia coli DNA-polymerase-deficient assay system.
Hydratropic alcohol did not increase the number of sister chromatid exchanges in human lymphocytes
Hydratropic alcohol is an aromatic chemical, usually appearing as a clear oily liquid with a sweet rose scent.
Hydratropic alcohol can be synthesized for industry through the use of yeast strains or by reacting benzene and ethylene oxide with a catalyst.
Hydratropic alcohol is naturally present in grapes and wines, and is also found in the essential oils of many plants such as ylang ylang, hyacinth and carnation.
Hydratropic alcohol is the dominant odour in fresh roses such as Rosa multiflora, however is mostly lost during essential oil production as Hydratropic alcohol separates, with only a fraction remaining in rose oil.
Hydratropic alcohols are a large class of important cosmetic ingredients but only ethanol needs to be denatured to prevent Hydratropic alcohol from being redirected from cosmetic applications to alcoholic beverages.
Hydratropic alcohol did inhibit the repair of radiation-induced breaks in the DNA of Z. coli.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Hydratropic alcohol is prepared commercially via two routes.
Most common is the Friedel-Crafts reaction between benzene and ethylene oxide in the presence of aluminium trichloride.
C6H6 + CH2CH2O + AlCl3 → C6H5CH2CH2OAlCl2 + HCl
The reaction affords the aluminium alkoxide that is subsequently hydrolyzed to the desired product.
The main side product is Hydratropic alcohol, which can be avoided by use of excess benzene.
Hydratropic alcohol of styrene oxide also affords Hydratropic alcohol.
Hydratropic alcohol is found in extract of rose, carnation, hyacinth, Aleppo pine, orange blossom, ylang-ylang, geranium, neroli, and champaca.
Hydratropic alcohol is a colorless, transparent, slightly viscous liquid.
Hydratropic alcohol is used as an additive in cigarettes and also used as a preservative in soaps due to Hydratropic alcohol stability in basic conditions.
Hydratropic alcohol is the deuterium labeled Hydratropic alcohol.
Hydratropic alcohol, extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid.
Hydratropic alcohol has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans.
Hydratropic alcohol is used as an additive in cigarettes and also used as a preservative in soaps due to Hydratropic alcohol stability in basic conditions.
Hydratropic alcohol occurs naturally in some essential oils, such as rose oil, carnation oil, and geranium oil, contributing to their pleasant fragrance.
Hydratropic alcohol is commonly used in the perfume and flavor industries due to Hydratropic alcohol floral aroma.
Additionally, Hydratropic alcohol has antimicrobial properties, which makes Hydratropic alcohol useful in various cosmetic and personal care products as a preservative.
Hydratropic alcohol occurs naturally in various plants, including roses, carnations, geraniums, and other flowers.
Hydratropic alcohol is extracted from these sources for use in the fragrance industry.
One of the primary uses of Hydratropic alcohol is in the fragrance and perfume industry.
Hydratropic alcohol is pleasant, floral scent, reminiscent of roses, makes Hydratropic alcohol a popular choice for adding a sweet and rosy note to perfumes and cosmetic products.
In cosmetics and personal care products, Hydratropic alcohol is used in the formulation of eye area makeup, makeup products, skin care products, shampoos and perfumes and colognes.
Hydratropic alcohol is a primary alcohol that is ethanol substituted by a phenyl group at position 2.
Hydratropic alcohol has a role as a fragrance, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Aspergillus metabolite and a plant growth retardant.
Hydratropic alcohol is a primary alcohol and a member of benzenes.
Hydratropic alcohol is a water soluble fragrance agent with rose like scent and good antimicrobial activity.
Perfect suitable for water based products and colour cosmetics.
The combination with boosting agents is in emulsions recommendable, the performance is pH independent.
Hydratropic alcohol is an organic compound with the chemical formula C6H5CH2CH2OH.
Hydratropic alcohol is a colourless liquid with a pleasant floral odor.
Hydratropic alcohol occurs widely in nature, being found in a variety of essential oils.
Hydratropic alcohol is slightly soluble in water (2 ml per 100 ml of H2O), but miscible with most organic solvents.
The molecule of Hydratropic alcohol consists of a phenethyl group (C6H5CH2CH2−) attached to a hydroxyl group (−OH).
In addition to its use in perfumery, Hydratropic alcohol is sometimes used as a flavoring agent in the food industry, providing a sweet and floral taste to certain products.
Hydratropic alcohol has antimicrobial properties, and as such, Hydratropic alcohol is employed as a preservative in various cosmetic and personal care products.
Hydratropic alcohol helps extend the shelf life of these products by inhibiting the growth of bacteria and fungi.
Hydratropic alcohol can be synthesized chemically through various methods, including the reduction of phenylacetic acid or the hydration of styrene.
Synthetic Hydratropic alcohol is often used in the fragrance industry when a cost-effective and consistent source is needed.
Hydratropic alcohol can act as a solvent for various substances, which adds to its versatility in different industrial applications.
Hydratropic alcohol is generally considered safe for use in cosmetics and personal care products when used in accordance with regulations.
However, like any chemical, Hydratropic alcohol should be handled with care, and its concentration in formulations should comply with safety guidelines.
Hydratropic alcohol, extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid that is slightly soluble in water.
Hydratropic alcohol has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans.
Hydratropic alcohol is a colorless liquid with a mild rose odor.
Hydratropic alcohol can be dehydrogenated catalytically to phenylacetaldehyde and oxidized to phenylacetic acid (e.g.,with chromic acid).
Hydratropic alcohol is the main component of rose oils obtained from rose blossoms
Hydratropic alcohol occurs in smaller quantities in neroli oil, ylang-ylang oil, carnation oil, and geranium oils.
Since the alcohol is rather soluble in water, losses occur when essential oils are produced by steam distillation.
Hydratropic alcohol is fatty acid esterswith lowermolecularmass, as well as some alkyl ethers, are valuable fragrance and flavor substances.
Phenylethyl Alcohol is found in almond.
Hydratropic alcohol is a component of ylang-ylang oil.
Hydratropic alcohol is a flavouring ingredient.
Hydratropic alcohol is also called P-Hydratropic alcohol, p-phenyl ethyl alcohol, 2-phenyl ethanol, benzeneethanol, benzyl carbinol, and p-hydroxyethylben~ene.'~-~) PEA is a colorless, transparent, slightly viscous liquid with a sharp, burning taste.
Hydratropic alcohol has a floral odor with a rose chara~ter.'~?~,~) The molecular weight of PEA is 122.1 7.
Hydratropic alcohol has a specific gravity of 1.0202 at 20°C (compared with water at 4°C) and a specific gravity of 1.01 7 to 1.01 9 at 25°C (compared with water at 25°C).
Hydratropic alcohol is also soluble in fixed oils, glycerol, and propylene glycol and is slightly soluble in mineral oil.
A 2-ml sample of Hydratropic alcohol will dissolve in 100 ml of water after thorough Exposure to air may cause a slight oxidation of Hydratropic alcohol.
Hydratropic alcohol can be oxidized by acids and other oxidants, and oxidation in the presence of air is accelerated by heat.
Hydratropic alcohol is stable in colorless glass ampules at room temperature or in full opaque containers stored at 4 to 27°C for up to 1 year.
Hydratropic alcohol is absorbed by polyethylene c~ntainers.(~,~,~) PEA occurs naturally in the environment.
Hydratropic alcohol is produced by microorganisms, plants, and animals."0)
Hydratropic alcohol has been found as the free alcohol oresterified in a number of natural essential oils, and in food, spices, and tobacco.
Hydratropic alcohol is used as a preservative ingredient in some soaps, and is also used in cosmetics, personal care products and food production for creating floral-rose fragrances and flavours.
Hydratropic alcohol can be produced through various methods, including chemical synthesis and natural extraction from plants such as rose and jasmine.
The most common method involves the reduction of benzaldehyde with sodium borohydride in the presence of a catalyst.
The boiling point of Hydratropic alcohol at 750 mm Hg is 219 to 221"C, at 14 mm Hg is 104"C, at 12 mm Hg is 98 to 1 OO"C, and at 10 mm Hg is 97.4"C.
The freezing point of Hydratropic alcohol is -27°C.
The alcohol is combustible, and Hydratropic alcohol flash point is 102.2"C.
Hydratropic alcohol is a Hydratropic alcohol that prevents or retards bacterial growth, and thus protects cosmetics and personal care products from spoilage.
Hydratropic alcohol is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence.
Hydratropic alcohol is a natural and multifunctional ingredient with a pleasant floral odor.
Due to Hydratropic alcohol excellent antimicrobial properties Hydratropic alcohol is used in cosmetics as a preservative booster to reduce traditional preservative use.
Contrarily to organic salt preservatives which require a low pH for optimum action, Hydratropic alcohol is pH independent.
Hydratropic alcohol is efficient in a broad pH range and heat stable.
For this reason, Hydratropic alcohol can be used in all kinds of products in cosmetics and perfumery, as a deodorant active and for alternative preservation.
Hydratropic alcohol is soluble in water and in most organic solvents.
Hydratropic alcohol, or Hydratropic alcohol, is the organic compound that consists of a phenethyl group group attached to OH.
Hydratropic alcohol is a colourless liquid that is slightly soluble in water, but miscible with most organic solvents.
Incompatible with oxidizing agents and protein, e.g. serum.
Hydratropic alcohol is partially inactivated by polysorbates, although this is not as great as the reduction in antimicrobial activity that occurs with parabens and polysorbates.
Purify the ethanol by shaking Hydratropic alcohol with a solution of ferrous sulfate, and the alcohol layer is washed with distilled water and fractionally distilled.
Hydratropic alcohol was not mutagenic in bacterial assays, nor did Hydratropic alcohol increase the number of sister chromatid exchanges in human lymphocytes.
Hydratropic alcohol can also be prepared by the reaction between phenylmagnesium bromide and ethylene oxide:
C6H5MgBr + CH2CH2O → C6H5CH2CH2OMgBr
C6H5CH2CH2OMgBr + H+ → C6H5CH2CH2OH + MgBr+
The index of refraction for Hydratropic alcohol at 20°C for sodium light is 1.530 to 1.534.(2~4-6) Hydratropic alcohol is very soluble in alcohol and ether.
Hydratropic alcohol can also be produced by biotransformation from L-phenylalanine using immobilized yeast Saccharomyces cerevisiae.
Proper storage conditions, such as keeping Hydratropic alcohol in a cool and dark place, are important to maintain Hydratropic alcohol quality.
The environmental impact of Hydratropic alcohol depends on factors such as its source (natural or synthetic) and the specific application.
In general, when used responsibly and in accordance with regulations, Hydratropic alcohol impact on the environment is considered minimal.
Hydratropic alcohol is also possible to produce Hydratropic alcohol by the reduction of phenylacetic acid using sodium borohydride and iodine in THF.
Hydratropic alcohol is found in extract of rose, carnation, hyacinth, Aleppo pine, orange blossom, ylang-ylang, geranium, neroli, and champaca.
Hydratropic alcohol is also used as a preservative in soaps due to its stability in basic conditions.
Hydratropic alcohol is of interest due to its antimicrobial properties.
Besides being found in essential oils of plants, Hydratropic alcohol is a natural component of some fruits.
Hydratropic alcohol contributes to the characteristic aroma of certain fruits like apples and strawberries.
There is ongoing research into the potential therapeutic properties of Hydratropic alcohol.
Some studies suggest that Hydratropic alcohol may have anti-inflammatory and antioxidant effects.
However, more research is needed to fully understand Hydratropic alcohol potential medical applications.
Hydratropic alcohol is used in various industrial processes.
For example, Hydratropic alcohol can be utilized as a precursor in the synthesis of other chemicals, including pharmaceuticals and agrochemicals.
Hydratropic alcohol is present in trace amounts in wine and is considered one of the volatile compounds that contribute to the overall aroma and flavor profile of the wine.
In perfumery, Hydratropic alcohol is often used in combination with other aromatic compounds to create complex and well-balanced fragrances.
Hydratropic alcohol is mild and floral scent makes Hydratropic alcohol a versatile ingredient in fragrance formulations.
The use of Hydratropic alcohol is subject to regulations and guidelines set by regulatory authorities in different countries.
Hydratropic alcohol is important for industries to comply with these regulations to ensure the safety and proper labeling of products containing this compound.
Hydratropic alcohol is relatively stable, but like many chemicals, Hydratropic alcohol can degrade over time, especially when exposed to light and air.
Hydratropic alcohol is a compound naturally present in various fruits, flowers, and plants.
In laboratory studies, Hydratropic alcohol has demonstrated the ability to influence the activity of specific enzymes, receptors, and channels.
Notably, Hydratropic alcohol has been observed to inhibit the enzyme acetylcholinesterase.
Additionally, research has explored Hydratropic alcohol potential in modulating the activity of G-protein coupled receptors, which play crucial roles in a wide range of physiological processes.
Uses of Hydratropic Alcohol:
Hydratropic alcohol is used in the formulation of room sprays and air fresheners to provide a pleasant and long-lasting fragrance.
Hydratropic alcohol can be found in nail polishes, nail polish removers, and other nail care products due to Hydratropic alcohol fragrance and potential antimicrobial benefits.
Hydratropic alcohol is an aromatic alcohol used as a flavoring agent in the cosmetic, perfume, and food industries.
Other release to the environment of Hydratropic alcohol is likely to occur from: indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
Hydratropic alcohol is intended to be released from scented: clothes, eraser, toys, paper products and CDs.
Widespread uses by professional workers
Hydratropic alcohol is used in the following products: polishes and waxes, washing & cleaning products, pH regulators and water treatment products, laboratory chemicals and cosmetics and personal care products.
Hydratropic alcohol is used in the following areas: health services and scientific research and development.
Other release to the environment of Hydratropic alcohol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.
Hydratropic alcohol is used in both aqueous and alcoholic perfume formulations, contributing to the fragrance stability in various types of perfumes.
In the formulation of biodegradable and environmentally friendly cleaners, Hydratropic alcohol may be used for its cleaning properties and mild scent
In niche and artisanal perfumery, where unique and specialized fragrances are crafted, Hydratropic alcohol is valued for its floral and versatile characteristics.
In the production of botanical extracts used in skincare and cosmetic formulations, Hydratropic alcohol may be employed for its aromatic qualities.
Hydratropic alcohol is qualitatively and quantitatively one of the most important fragrance substances that belongs to the class of araliphatic alcohols.
Hydratropic alcohol is used frequently and in large amounts as a fragrance material.
Hydratropic alcohol is a popular component in rose-type compositions, but Hydratropic alcohol is also used in other blossom notes.
Hydratropic alcohol is stable to alkali and, therefore, ideally suited for use in soap perfumes.
Hydratropic alcohol is used to mask odor and also as a preservative.
Hydratropic alcohol may be employed in the pharmaceutical industry as an ingredient in certain drug formulations.
Hydratropic alcohol is antimicrobial properties can contribute to the stability and preservation of pharmaceutical products.
The mild and pleasant scent of Hydratropic alcohol makes Hydratropic alcohol suitable for use in insect repellents.
Hydratropic alcohol can be included in formulations to improve the overall fragrance of these products.
Hydratropic alcohol is sometimes used in the production of scented candles and air fresheners to impart a floral fragrance, enhancing the ambiance of living spaces.
Beyond cosmetics, Hydratropic alcohol is often included in various personal care products such as shampoos, conditioners, and body lotions for Hydratropic alcohol fragrance and preservative properties.
Due to its solvent properties, Hydratropic alcohol can be used in the textile industry for processes like dyeing and finishing fabrics.
Hydratropic alcohol may be found in a range of household products, including cleaning solutions, fabric softeners, and laundry detergents, where Hydratropic alcohol antimicrobial properties contribute to product preservation.
In microbiology labs, Hydratropic alcohol is sometimes used as a disinfectant or as part of media formulations for culturing microorganisms.
Hydratropic alcohol's antimicrobial properties make Hydratropic alcohol a potential candidate for use in food packaging materials to inhibit the growth of microorganisms and extend the shelf life of packaged foods.
Hydratropic alcohol can be found in hair care products such as shampoos, conditioners, and styling products due to Hydratropic alcohol pleasing fragrance and preservative properties.
Hydratropic alcohol might be included in grooming sprays for pets to provide a pleasant scent and potentially help in controlling odors.
Some dental products, such as mouth rinses and dental gels, may contain Hydratropic alcohol for its potential antimicrobial effects and fragrance.
Beyond its use as a flavoring agent in the food industry, Hydratropic alcohol is sometimes employed in the creation of floral and fruity flavorings for various food products.
In some culinary applications, Hydratropic alcohol might be used to enhance the aroma and flavor of specific dishes or desserts.
Hydratropic alcohol is used as a preservative in cleansers, toners, moisturizers, and other cosmetic formulations.
Hydratropic alcohol helps in extending the shelf life of products and protects against harmful microorganisms.
Additionally, the skin conditioning properties of Hydratropic alcohol make it a popular ingredient in moisturizers and other skincare products
Cosmetic products: Apart from acting as a preservative, Hydratropic alcohol is commonly used as a fragrance ingredient, adding a floral scent to cosmetic products.
Hydratropic alcohol can be found in a wide range of cosmetics, including foundations, blushes and eye shadows.
Hydratropic alcohol is used in food flavors, especially in honey, bread, apple, rose flavor and so on.
Hydratropic alcohol is used in tobacco flavors.
Hydratropic alcohol is used for blending rose essential oil and all kinds of fragrance, such as jasmine, lilac, and orange blossom fragrance, etc.
Hydratropic alcohol is used as an additive in cigarettes.
Hydratropic alcohol is a common ingredient in the fragrance and perfume industry.
Hydratropic alcohol can be found in various food and beverage items.
Due to its antimicrobial properties, Hydratropic alcohol is used as a preservative in cosmetics, skincare products, and toiletries.
Hydratropic alcohol helps prevent the growth of bacteria and fungi, extending the shelf life of these products.
Hydratropic alcohol serves as a solvent in industrial processes, contributing to Hydratropic alcohol versatility.
Hydratropic alcohol can be used in the synthesis of various chemicals, including pharmaceuticals and agrochemicals.
While still being explored, research suggests that Hydratropic alcohol may have potential therapeutic properties.
Hydratropic alcohol has been studied for its anti-inflammatory and antioxidant effects, but more research is needed to confirm these findings.
Natural Hydratropic alcohol found in some fruits contributes to the characteristic aroma and flavor of certain foods, including apples and strawberries.
Hydratropic alcohol is present in trace amounts in wine and contributes to its overall aroma and flavor profile.
Hydratropic alcohol is considered one of the volatile compounds influencing the sensory characteristics of wine.
The antimicrobial properties of Hydratropic alcohol make it a suitable ingredient in some household cleaning products, detergents, and disinfectants.
Hydratropic alcohol's pleasant scent makes it suitable for use in aromatherapy products, such as essential oil blends or diffuser oils.
Hydratropic alcohol is used in research and development laboratories, often as a reference compound or as a starting material in chemical synthesis.
Hydratropic alcohol is used as an antimicrobial preservative in nasal, ophthalmic, and otic formulations at 0.25–0.5% v/v concentration; Hydratropic alcohol is generally used in combination with other preservatives.
Hydratropic alcohol has also been used on its own as an antimicrobial preservative at concentrations up to 1% v/v in topical preparations.
At this concentration, mycoplasmas are inactivated within 20 minutes, although enveloped viruses are resistant.
Hydratropic alcohol is also used in flavors and as a perfumery component, especially in rose perfumes.
Hydratropic alcohol is sweet, floral scent, reminiscent of roses, makes Hydratropic alcohol a popular choice for adding a rosy note to perfumes and personal care products.
Hydratropic alcohol is sometimes used in the production of herbal extracts and tinctures, contributing to the overall aroma of the final product.
The antimicrobial properties of Hydratropic alcohol make it a suitable ingredient in liquid soaps and body washes, helping to keep the products free from harmful microorganisms.
Hydratropic alcohol may be included in some mouthwashes and oral care products for its antimicrobial effects and to enhance the product's overall scent.
Some pet grooming products, such as shampoos and conditioners, may contain Hydratropic alcohol for its fragrance and preservative qualities.
Hydratropic alcohol can be found in floral waters and hydrosols, contributing to the aromatic properties of these products.
Consumer Uses:
Hydratropic alcohol is used in the following products: biocides (e.g. disinfectants, pest control products), air care products, perfumes and fragrances, cosmetics and personal care products, polishes and waxes, washing & cleaning products and pharmaceuticals.
Other release to the environment of Hydratropic alcohol is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Widespread uses by professional workers:
Hydratropic alcohol is used in the following products: polishes and waxes, washing & cleaning products, pH regulators and water treatment products, laboratory chemicals and cosmetics and personal care products.
Hydratropic alcohol is used in the following areas: health services and scientific research and development.
Other release to the environment of Hydratropic alcohol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.
Uses at industrial sites:
Hydratropic alcohol is used in the following products: washing & cleaning products, air care products, pH regulators and water treatment products and laboratory chemicals.
Hydratropic alcohol is used in the following areas: health services and scientific research and development.
Hydratropic alcohol is used for the manufacture of: chemicals.
Release to the environment of Hydratropic alcohol can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.
Occurrence and uses of Hydratropic Alcohol:
Hydratropic alcohol is found in extract of rose, carnation, hyacinth, Aleppo pine, orange blossom, ylang-ylang, geranium, neroli, and champaca.
Hydratropic alcohol is also an autoantibiotic produced by the fungus Candida albicans.
Hydratropic alcohol is therefore a common ingredient in flavors and perfumery, particularly when the odor of rose is desired.
Hydratropic alcohol is used as an additive in cigarettes.
Hydratropic alcohol is also used as a preservative in soaps due to its stability in basic conditions.
Hydratropic alcohol is of interest due to its antimicrobial properties.
Production of Hydratropic Alcohol:
Many syntheticmethods are known for preparing Hydratropic alcohol.
The following are currently of industrial importance:
1) Friedel–Crafts reaction of benzene and ethylene oxide:
In the presence of molar quantities of aluminum chloride, ethylene oxide reacts with benzene to give an addition product, which is hydrolyzed to phenylethyl alcohol:
Friedel–Crafts reaction of benzene and ethylene oxide.
Formation of by-products, such as 1,2-diphenylethane, is largely avoided by using an excess of benzene at low temperature.
Special purification procedures are required to obtain a pure Hydratropic alcohol that is free of chlorine and suitable for use in perfumery.
2) Hydrogenation of styrene oxide: Excellent yields of Hydratropic alcohol are obtainedwhen styrene oxide is hydrogenated at low temperature, using Raney nickel as a catalyst and a small amount of sodium hydroxide.
Synthesis of Hydratropic Alcohol:
Hydratropic alcohol is prepared commercially via two routes.
Most common is the Friedel-Crafts reaction between benzene and ethylene oxide in the presence of aluminium trichloride.
C6H6 + CH2CH2O + AlCl3 → C6H5CH2CH2OAlCl2 + HCl
The reaction affords the aluminium alkoxide that is subsequently hydrolyzed to the desired product.
The main side product is diphenylethane, which can be avoided by use of excess benzene.
Hydrogenation of styrene oxide also affords Hydratropic alcohol.
Laboratory methods:
Hydratropic alcohol can also be prepared by the reaction between phenylmagnesium bromide and ethylene oxide:
C6H5MgBr + CH2CH2O → C6H5CH2CH2OMgBr
C6H5CH2CH2OMgBr + H+ → C6H5CH2CH2OH + MgBr+
Hydratropic alcohol can also be produced by biotransformation from L-phenylalanine using immobilized yeast Saccharomyces cerevisiae.
Hydratropic alcohol is also possible to produce Hydratropic alcohol by the reduction of phenylacetic acid using sodium borohydride and iodine in THF.
Handling and storage of Hydratropic Alcohol:
Storage:
Hydratropic alcohol is stable in bulk, but is volatile and sensitive to light and oxidizing agents.
If stored in low-density polyethylene containers, Hydratropic alcohol may be absorbed by the containers.
The bulk material should be stored in a well-closed container, protected from light, in a cool, dry place.
Hydratropic alcohol is reasonably stable in both acidic and alkaline solutions.
Aqueous solutions may be sterilized by autoclaving.
Losses to polypropylene containers have been reported to be insignificant over 12 weeks at 30°C.
Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Storage class:
Storage class (TRGS 510): 10: Combustible liquids
Stability and reactivity of Hydratropic Alcohol:
Reactivity:
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Chemical stability:
Hydratropic alcohol is chemically stable under standard ambient conditions (room temperature) .
Stable under recommended storage conditions.
May form peroxides on prolonged storage.
Date container and periodically test for peroxides.
Possibility of hazardous reactions:
No data available
Conditions to avoid:
Strong heating.
Incompatible materials:
No data available
Safety Profile of Hydratropic Alcohol:
Moderately toxic by ingestion and skin contact.
Hydratropic alcohol can be produced through various methods, including chemical synthesis and natural extraction from plants such as rose and jasmine.
The most common method involves the reduction of benzaldehyde with sodium borohydride in the presence of a catalyst.
The resulting Hydratropic alcohol is then purified to obtain Hydratropic alcohol.
Hydratropic alcohol a skin and eye irritant.
When heated to decomposition Hydratropic alcohol emits acrid smoke and irritating fumes
Hydratropic alcohol is generally regarded as a nontoxic and nonirritant material.
However, at the concentration used to preserve eye-drops (about 0.5% v/v) or above, eye irritation may occur.
Experimental teratogenic effects.
Other experimental reproductive effects.
Causes severe central nervous system injury to experimental animals.
Combustible when exposed to heat or flame; can react with oxidzing materials.
First aid measures of Hydratropic Alcohol:
General advice:
Show this material safety data sheet to the doctor in attendance.
If inhaled:
After inhalation:
Fresh air.
In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
If swallowed:
After swallowing:
Caution if victim vomits.
Risk of aspiration!
Keep airways free.
Pulmonary failure possible after aspiration of vomit.
Call a physician immediately.
Indication of any immediate medical attention and special treatment needed:
No data available
Firefighting measures of Hydratropic Alcohol:
Suitable extinguishing media:
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
Special hazards arising from the substance or mixture:
Carbon oxides
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus.
Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Accidental release measures of Hydratropic Alcohol:
Personal precautions, protective equipment and emergency procedures:
Advice for non-emergency personnel:
Do not breathe vapors, aerosols.
Avoid substance contact.
Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.
Environmental precautions:
Do not let product enter drains.
Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.
Identifiers of Hydratropic Alcohol:
CAS number: 60-12-8
EC number: 200-456-2
Hill Formula: C₈H₁₀O
Chemical formula: C₆H₅CH₂CH₂OH
Molar Mass: 122.17 g/mol
HS Code: 2906 29 00
CAS Number: 60-12-8
ChEBI: CHEBI:49000
ChEMBL: ChEMBL448500
ChemSpider: 5830
DrugBank: DB02192
ECHA InfoCard: 100.000.415
KEGG: D00192
PubChem CID: 6054
UNII: ML9LGA7468
CompTox Dashboard (EPA): DTXSID9026342
InChI: InChI=1S/C8H10O/c9-7-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2
Key: WRMNZCZEMHIOCP-UHFFFAOYSA-N
InChI=1S/C8H10O/c9-7-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2
InChI=1S/C8H10O/c9-7-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2
Key: WRMNZCZEMHIOCP-UHFFFAOYSA-N
SMILES: c1ccc(cc1)CCO
CAS Number: 60-12-8
Molecular Weight: 122.16
Beilstein: 1905732
EC Number: 200-456-2
MDL number: MFCD00002886
PubChem Substance ID: 57652684
NACRES: NA.22
Properties of Hydratropic Alcohol:
Melting point: -27 °C (lit.)
Boiling point: 219-221 °C/750 mmHg (lit.)
Density: 1.020 g/mL at 20 °C (lit.)
vapor density: 4.21 (vs air)
vapor pressure: 1 mm Hg ( 58 °C)
refractive index: n20/D 1.5317(lit.)
FEMA: 2858 | Hydratropic alcohol
Flash point: 216 °F
storage temp.: Store below +30°C.
solubility: Miscible with chloroform.
form: Liquid
pka: 15.17±0.10(Predicted)
color: Clear colorless
Odor: floral odor of roses
PH: 6-7 (20g/l, H2O, 20℃)
explosive limit 1.4-11.9%(V)
Odor Type: floral
Water Solubility: 20 g/L (20 ºC)
Merck: 14,7224
JECFA Number: 987
BRN: 1905732
Dielectric constant: 13.0(20℃)
Stability: Stable. Substances to be avoided include strong acids and strong oxidizing agents. Combustible.
InChIKey: WRMNZCZEMHIOCP-UHFFFAOYSA-N
LogP: 1.50
Chemical formula: C8H10O
Molar mass: 122.167 g·mol−1
Odor: Soft, like roses
Density: 1.017 g/cm3
Melting point: −27 °C (−17 °F; 246 K)
Boiling point: 219 to 221 °C (426 to 430 °F; 492 to 494 K)
log P: 1.36
vapor density: 4.21 (vs air)
Quality Level: 100
vapor pressure: 1 mmHg ( 58 °C)
Assay: ≥99.0% (GC)
form: liquid
refractive index: n20/D 1.5317 (lit.)
bp: 219-221 °C/750 mmHg (lit.)
mp: −27 °C (lit.)
density: 1.020 g/mL at 20 °C (lit.)
SMILES string: OCCc1ccccc1
InChI: 1S/C8H10O/c9-7-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2
InChI key: WRMNZCZEMHIOCP-UHFFFAOYSA-N
Boiling point: 219 °C (1013 hPa)
Density: 1.023 g/cm3 (20 °C)
Explosion limit: 1.4 - 11.9 %(V)
Flash point: 102 °C
Ignition temperature: 410 °C
Melting Point: -27 °C
pH value: 6 - 7 (20 g/l, H₂O, 20 °C)
Vapor pressure: 0.08 hPa (20 °C)
Solubility: 20 g/l
Specifications of Hydratropic Alcohol:
Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.019 - 1.020
Identity (IR): passes test
Names of Hydratropic Alcohol:
Regulatory process names:
Hydratropic alcohol
Hydratropic alcohol
beta-Phenylethyl alcohol; Phenethyl alcohol
IUPAC names:
2-FENYLETHANOL
2-Phenyethanol
2-phenyl ethl acohol
2-Phenyl ethyl alcohol
2-phenylethan-1-ol
Hydratropic alcohol
Hydratropic alcohol
Hydratropic alcohol
Hydratropic alcohol
2-Phenylethyl Alcohol
2-Phenylethyl alcohol
Benzeneethanol
p-menth-1-en-8-ol
PEA
PEA, Hydratropic alcohol
Phenethyl alcohol
PHENYL ETHYL ALCOHOL
Phenyl Ethyl Alcohol
phenyl ethyl alcohol
Phenyl Ethyl Alcohol
Phenylethyl alcohol
Phenylethylalcohol
β-PEA, Benzyl carbinol
Trade names:
2-PEA
PEA-PHENYL ETHYL PHENOL
Phenethyl alcohol
Phenyl Ethyl Alcohol
PHENYLROSE
Other names:
Hydratropic alcohol
Phenethyl alcohol
Benzyl carbinol
β-Hydroxyethylbenzene
Benzeneethanol
Other identifiers:
60-12-8
MeSH of Hydratropic Alcohol:
2 Phenylethanol
Hydratropic alcohol
Alcohol, Phenethyl
Alcohol, Phenylethyl
Benzyl Carbinol
beta Phenylethanol
beta-Phenylethanol
Carbinol, Benzyl
Phenethyl Alcohol
Phenylethanol
Phenylethyl Alcohol