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HYDROLIZED KERATIN

CAS NUMBER: 69430-36-0

EC NUMBER: 9008-18-8

MOLECULAR FORMULA: C2H2BrClO2

MOLECULAR WEIGHT: 173.39

IUPAC NAME: 2-bromo-2-chloroacetic acid


Hydrolyzed Keratin is essentially a large protein molecule that has gone through a chemical process that is broken down in a way that allows it to penetrate the hair cuticle. 
It is most popularly derived from wool protein, silk protein, or vegan wheat protein

Type of ingredient: Strengthener
Main benefits: Reduces breakage, minimizes damage, and increases elasticity and shine
Who should use Hydrolyzed Keratin: Curly, kinky, and dry/damaged hair
How often can you use Hydrolyzed Keratin: Every six to eight weeks
Works well with: Your average shampoo and conditioner

Simply put, hydrolyzed keratin protein gets the job done. 
Because Hydrolyzed Keratin has a low molecular weight
Hydrolyzed Keratin can penetrate the hair cuticle 
This helps Hydrolyzed Keratin to take effect with more potency than say, something that merely sits on top of the hair. 

 

Here's what we mean:

-Strengthens and protects: When hydrolyzed keratin is used topically on the hair, Hydrolyzed Keratin helps fill the minor gaps throughout the hair shaft, including its three layers known as the cuticle, cortex, and medulla. 
Filling these microscopic gaps with broken-down protein helps to strengthen hair's structure, thereby improving Hydrolyzed Keratins overall elasticity.

-Reduces damage: Hydrolyzed keratin minimizes the damaging effects of sun exposure, heat styling, chemical treatments, and combing hair—tangled tresses, especially.

-Fights frizz: Studies show that hydrolyzed keratin can improve hair's texture so that it looks and feels smoother.
In other words, Hydrolyzed Keratin's a frizz-fighting machine.

-Softens hair: After chemical treatments that use Hydrolyzed Keratin, hair will feel softer and bouncier.

-Moisturizes: According to Fishman, hydrolyzed keratin "acts as a humectant, which draws moisture into the hair."
Increases density: Hydrolyzed Keratin also helps to rebuild the natural protective layer of hair from the inside by replacing lost protein and increasing each strand’s diameter, which gives it a fuller appearance

Hydrolyzed Keratin is beneficial for most hair types, but will have more benefits for people with curly, kinky, dry, or damaged hair. 
High porosity hair types that have been weakened from chemical processes like color treatments, chemical relaxers, or sun damage benefit from keratin treatments
The hydrolyzed keratin will fill the gaps in the hair strands that are weak.
However, Hydrolyzed Keratin’s a powerful ingredient
So Hydrolyzed Keratin shouldn’t be applied as often as, say, a moisturizing deep conditioner.

 

What Is Hydrolyzed Keratin?
Firstly, keratin is a protein that’s naturally found in your hair.
Hydrolyzed Keratin’s responsible for your hair’s health.
While keratin makes your hair strong, Hydrolyzed Keratin’s also prone to damage due to environmental aggressors.

For this reason, Hydrolyzed Keratin has been introduced into several hair care formulations to supplement what has been weakened.
Hydrolyzed Keratin is a large protein molecule that is broken down after a chemical process in a manner such that it can penetrate the hair cuticle. 
Hydrolyzed Keratin is sourced from a larger keratin molecule.

Keratin is broken down by splitting Hydrolyzed Keratins bond with the addition of hydrogen and hydroxide (water). 
At the end of the chemical process, the keratin is reduced into smaller fragments that the hair can absorb, thanks to its lower molecular weight.
Essentially, hydrolyze means to fragment the protein or break into smaller pieces in a non-specific manner. 
The broken-down proteins deposit themselves on the hair’s shaft.
Due to the low molecular weight and the small size, the hydrolyzed keratin proteins go beyond the cuticle, penetrate the hair shaft and reduce damage.
Hydrolyzed Keratin is a multifunctional and go-to strengthening protein that helps your damaged hair turn over a new leaf.

 

Where Does Hydrolyzed Keratin Come From?
Hydrolyzed Keratin is naturally produced within the body, just like biotin. 
Hydrolyzed Keratin, a water-soluble vitamin, assists in the metabolism of protein which provides a foundation for keratin.

You can also find Hydrolyzed Keratin in food sources. 
Foods high in vitamin C, biotin, lean protein and whole grains are keratin-rich and improve keratin in your nails and hair.
Topical products like nail treatments, lotions, shampoo and conditioner also contain hydrolyzed keratin.

 

What Does Hydrolyzed Keratin Do To Your Hair?
When you use Hydrolyzed Keratin on your hair topically, it helps fill the minor gaps throughout the hair shaft, including its three layers - the medulla, cortex and cuticle. 
Hydrolyzed Keratin’s like pouring cement into a crack.
When the broken down protein fills these microscopic gaps, hair gets the strength to minimize damage from chemical treatments, heat styling, mechanical manipulation and the sun.

 

Here Are some Of Hydrolyzed Keratins Other Benefits:
-Reduces frizz, shedding and breakage.
-Increases smoothness and elasticity with its moisture-binding abilities.
-Essentially, hydrolyzed keratin helps rebuild the hair’s natural protective layer from the inside by increasing the diameter of each strand. 
This gives a fuller appearance and replaces lost protein.

-When hair treatments contain broken down or hydrolyzed keratin, it creates a protective barrier on the hair and simultaneously imparts shine.
-Hydrolyzed keratin works on the skin too, and it restores moisture and improves the elasticity of the skin.
-Hydrolyzed Keratins moisturizing properties make shampoos and conditioners that contain hydrolyzed keratin a go-to option for those with brittle, dry or limp hair.
-Hydrolyzed Keratin’s an excellent choice to tame unruly hair and make it more manageable.
-As hair is made from keratin, it’s one of the best proteins to treat hair that’s heavily manipulated or chemically damaged. Usually, when hair undergoes chemical processes, the amino acid cysteine breaks down and results in weakened and damaged hair. 
Keratin is known to replace this lost cysteine. 
Hydrolyzed keratin increases cysteine content, which increases tensile strength and minimizes damage.
-Hydrolyzed Keratin also increases volume, strengthens your hair, and restores luster

-Research shows that hydrolyzed protein can repair and condition damaged hair. 
These protein hydrolysates strengthen hair fibers and reduce hair breakage
-Protein hydrolysates are often added to hair coloring products for even color absorption.
-Hydrolyzed protein protects the hair from the damaging effects of permanent bleaching, waving, and straightening products

-Hydrolyzed Keratin improves the texture and natural structure of the hair and forms a protective coating to shield the strands
-Hydrolyzed Keratin boosts hair moisture and elasticity and protects it from heat and photo-damage
-Hydrolyzed Keratin retains water content in the cortex by bonding with residual amino acids produced by hair proteins
-Research shows that hydrolyzed keratin can help stimulate hair growth
-Protein hydrolysates protect the hair from chemical and environmental aggressors to prevent hair damage

-Hydrolyzed Keratin also helps seal hair cuticles. 
This minimizes frizz and prevents flyaways. 
The amino acids from hydrolyzed proteins neutralize the negative electrical charge on the hair to eliminate frizz and friction.
-Hydrolyzed keratin has a similar amino acid structure to that of natural human hair. 
-Hydrolyzed Keratin is known to improve the tensile strength of damaged hair
This multifunctional ingredient can fortify the hair and improve its overall health and appearance.

-Hydrolyzed keratin is extracted from the nails, wools, and horns of animals. 
-Hydrolyzed Keratin is a large protein molecule and is broken down or “hydrolyzed” into smaller molecules through enzymatic hydrolysis. 
The smaller or hydrolyzed molecules have lower molecular weight and penetrate the hair shafts and strengthen the hair structure. 
Hydrolyzed Keratin has a similar amino acid structure as the keratin produced naturally in humans. 

Is Hydrolyzed Keratin Good For Curly Hair?
Yes. This is because curly and kinky hair is porous and brittle and has a weak hair structure. 
Hydrolyzed keratin can easily penetrate curly hair and improve its protein content to strengthen the strands and enhance the hair structure. 
Hydrolyzed Keratin may help enhance curl definition

Curly hair is more prone to damage and dryness, and hydrolyzed keratin can help minimize these issues. 
Research shows that it makes curly hair more manageable and frizz-free
Hydrolyzed Keratin also improves hair color and shine.
If you want to reap all these benefits of hydrolyzed keratin, you need to use it the right way. 
Here are a few tips to help you use hydrolyzed keratin for your hair.

Hydrolyze means to break up into smaller pieces, in a nonspecific manner, basically to fragment the protein. 
The Hydrolyzed Keratin proteins have been broken down in order to deposit itself on to the hair shaft in the regions of porosity and damage due to it’s low molecular structure. 
The Hydrolyzed Keratin Proteins are small enough to go beyond the cuticle and penetrate the hair shaft due to it's low molecular weight; therefore, reducing damage.

Since hair is made from Keratin, it is by far the best protein to treat hair that has been damaged by chemicals and heavy manipulation. 
Hydrolyzed Keratin is known to replace the amino acid cysteine, which is lost during chemical processing. 
The cysteine bridges are broken, during the chemical process, resulting in a damaged and weakened hair. 

Hydrolyzed Keratin increases the amount of cysteine available to the hair, thus, minimizing damage and increasing tensile strength. 
Keratin has a unique strength and protective quality. 
Hydrolyzed Keratin Protein particles are known to fill in the cracks along damaged areas in the hair shaft subsequently strengthening the hair, increasing elasticity and volume. 
Due to its moisture binding capabilities, Hydrolyzed Keratin Protein increases the moisture content in the hair, restoring luster, body, and increasing manageability.

Hydrolyzed Keratin is a hydrolysate of keratin protein derived from acid, enzyme, and other method of hydrolysis, which has been applied in many areas including:

-feed and food industry
-pharmacy
-fertilizers
-pesticides
-environmental protection
-leather industry
-cosmetics

Specifically, this substance can be mixed with polyamide 6 blend to prepare nanofibres for adsorption of chromium
Moreover, Hydrolyzed Keratin may act as an effective component to fabricate shampoo, bath, and shower gel.2 In addition, this chemical can be used as an effective ingredient to produce odor-removing and deodorizing composition.
Besides, Hydrolyzed Keratin has been demonstrated to function as an useful agent for hair fixatives

Bromochloroacetic acid is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by bromine while a second is replaced by chlorine. 
A low-melting (27.5-31.5℃), hygroscopic crystalline solid, it can be formed during the disinfection (by chlorination) of water that contains bromide ions and organic matter, so can occur in drinking water as a byproduct of the disinfection process. 
Hydrolyzed Keratin is a monocarboxylic acid, an organochlorine compound and a 2-bromocarboxylic acid.

Hydrolyzed Keratin is a fibrous protein of the epidermis and its adnexa such as hair and nails. 
Hydrolyzed Keratin enhances and strengthens the structure of damaged hair and nails, restoring their polish and healthy look; besides it maintains a proper level of moisturizing.
In nail enamels and conditioners - Hydrolyzed Keratin regenerates the structure of damaged plaque and results in its hardening and strengthening, prevents hair breaking and splitting as well as bears extreme similarity to proteins existing in skin and hair.

Hydrolyzed Keratin is especially recommended for the production of conditioners for the following types of nails:

-yellow with discolorations,
-damaged and splitting,
-thin and easily cracking,
-breaking,
-with dried and cracking epidermis as well as preparations hiding nail irregularities and becoming the basis for enamel.

In hair conditioners, keratin supplements the lack of building components of a hair. 
Hydrolyzed Keratins particles build themselves in damaged places of hair sheath subsequently strengthening them and increasing their elasticity as well as volume by means of the creation of protective colloids which protect the hair against harmful effects of oxidative (paints) and reducing preparations.

 

APLLICATIONS:

-Hair and nail conditioners

-Hair sprays

-Nail enamels

-Bubble baths

-After-shaves

-Anti-dandruff shampoos and preparations

-Preparations for stylization of hair

-Permanent wave and bleaching preparations

-Preparations in the form of foam

-Regenerative hair conditioners (a type of "fluid hair")

-Fatty Acids and Conjugates

-Cosmetic

-Film forming

-Skin conditioning

-Hair conditioning

-Humectant

-Household Products

-Institutional Products

-Pet Care

-Personal Care

Storage:
-semi-dark
-clean place
-dry place
-in room temperature
Solubility: In water and alcohols but insoluble in fats

Hydrolyzed protein is a protein that has been broken down to its essential amino acids. The process of hydrolyzing proteins helps them to penetrate our hair strands. 
Hydrolyzing a protein is super beneficial for us because these proteins will then strengthen our strands from all comprehensively, inside and out. 
That means better coverage and protection for our hair
This is so because the process of hydrolyzing the protein makes it small enough to replenish and preserve our hair so much so that it’s like hair on steroids

Hydrolyzed Keratin is a strengthening protein that is extracted from sheeps’ wool.
Due to the similarities between hydrolyzed keratin and the keratin that is naturally found in our strands, hydrolyzed keratin works as an excellent “filler” for chipped cuticles and thinned strands.
This protein helps our strands gain softness, strength, and flatten cuticles by closing gaps along the length of the hair.
Hydrolyzed Keratin has also been known to mend split ends albeit temporarily.
Hydrolyzed Keratin Protein revitalizes hair’s natural protective layer while rebuilding its strength and returning the elasticity to the strands

Hydrolyzed Keratin, a halogenated disinfection byproduct commonly found in drinking water, juice, and cheese
Hydrolyzed Keratin is a very colorless solid in water and methanol
The Hydrolyzed Keratin peptide is extracted by using a natural keratin such as chicken feather or duck feather as a raw material 

Hydrolized Keratin maintains the health and youth of hair and nails and strengthens them: 
-hair is shinier
-less brittle
-hair loss is slowed down
-nails are more supple. 
Hydrolized Keratin strengthens skin by protecting from free radicals, and softens it and makes it more supple.

 

PHYSICAL PROPERTIES OF HYDROLIZED KERATIN:

Molecular Weight: 173.39    

Exact Mass: 171.89267    

Monoisotopic Mass: 171.89267    

Topological Polar Surface Area: 37.3 Ų    

Boiling Point: 215.0 °C

Melting Point: 31.5 °C

Flash Point: 110 °C

Solubility: In water, 2.5X10+5 mg/L

Density: 1.9848 g/cu cm

Vapor Pressure: 1.4X10-1 mm Hg

Hydrolized Keratin Revitalizes the hairs natural protective layer
Hydrolized Keratin rebuilds tensile strength
Hydrolized Keratin returns elasticity and reduces breakage. 

Hydrolized Keratin Has been shown to greatly reduce hair damage from harsh chemicals. 
Hydrolized Keratin Acts also as a protective care substance on the skin.

 

CHEMICAL PROPERTIES OF HYDROLIZED KERATIN:

LogP: 0.61

Henry's Law constant: 2.2X10-8 atm-cu m/mole

Stability/Shelf Life: Stable

pKa: 1.40 (est)

Heavy Atom Count: 6    

Formal Charge: 0    

Complexity: 64.6    

Isotope Atom Count: 0    

Defined Atom Stereocenter Count: 0    

Undefined Atom Stereocenter Count: 1    

Defined Bond Stereocenter Count: 0    

Undefined Bond Stereocenter Count: 0    

Covalently-Bonded Unit Count: 1    

Compound Is Canonicalized: Yes

XLogP3-AA: 1.3    

Hydrogen Bond Donor Count: 1    

Hydrogen Bond Acceptor Count: 2    

Rotatable Bond Count: 1    

Hydrolyzed Keratin is the key structural material making up the outer layer of human skin. 
Hydrolyzed Keratin is also the key structural component of hair and nails. 
Hydrolyzed Keratin appears as a light yellow powder.

Hydrolyzed Keratin is a Hair Conditioning ingredient and helps to increase the softness or smoothness of hair, reduce tangles, and to reduce surface roughness
Hydrolyzed Keratin penetrates the hair fiber and, being the main hair protein, provides restoration and strengthening of the hair. 
The association of Keratin with Amino Acids leaves the hair soft and resistant to breakage. 
The result is restructured, shiny and conditioned hair.

Keratin is a fibrous protein that is found in the nails, hair, and wool of sheep. 
Hydrolyzed Keratin offers protection and strength to our hair as it contains a good proportion of an amino acid known as cysteine that consists of sulfur. 
Hydrolyzed Keratin Protein Powder is essentially a large protein molecule that undergoes a chemical process of enzymatic hydrolysis that splits the bond with the addition of hydrogen and hydroxide. 
Due to this chemical process, the keratin is broken down into smaller fragments that can easily penetrate into the hair.

Hydrolyzed Keratin Powder is tested carefully during production to make it with minimum ash and the faintest odor. 
Hydrolysis of Keratin is produced by a combination of alkaline and enzymatic hydrolysis, which reduces its molecular weight. 
The combination of these properties makes Keratin Protein an ideal ingredient for conditioning the hair especially low porosity hair as well as skin. 

Protein also adds a natural film on hair which increases its shine and overall texture. 
Hydrolyzed Keratin is available in an aqueous form and has an amber color. 
Also, Hydrolyzed Keratin can be dissolved in water.

Keratin Protein powder pH level ranges from 5 to 5.8 and it contains around 20 to 23% of proteins which is also quite beneficial to treat curly hair issues and thus this protein-filled compound is used in all types of hair care applications such as:
-shampoos
-hair balms
-pomades
-conditioners
Moreover, Hydrolyzed Keratin Powder can also be found in some skincare applications like creams and lotions to nourish and condition the skin.

 

 

STORAGE OF HYDROLIZED KERATIN:

Hydrolized Keratin should be stored in tightly closed containers.
Hydrolized Keratin should be stored separately from other reagents.

Hydrolized Keratin should be stored in a moisture-free environment.
Hydrolized Keratin should be stored in a semi-dark and dry place.
Hydrolized Keratin should be stored at constant atmospheric pressure.

Hydrolized Keratin should be kept away from places where it can get moisture.
Hydrolized Keratin should preferably be stored in glass bottles.
Hydrolized Keratin should be stored in a clean, well-ventilated place.

 

SYNONYMS:

Bromochloroacetic acid
2-bromo-2-chloroacetic acid
Acetic acid, bromochloro-
Chlorobromoacetic acid
bromo(chloro)acetic acid
2-Bromo-2-chloroethanoic acid
Keratins
Keratin hydrolyzate
bromochloracetic acid
BrCH(Cl)COOH
bromochloroethanoic acid
BrCH(Cl)CO2H
Bromochloroacetic acid, 97%
Bromochloroacetic acid-[13C]
Bromochloroacetic acid, analytical standard
Bromochloroacetic acid 1000 microg/mL in Methyl-tert-butyl ether

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