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HYDROLYZED COLLAGEN

CAS NUMBER: 9007-34-5

EC NUMBER: 232-697-4

 

Hydrolyzed collagen is simply collagen that has been broken down, through a process called hydrolysis, into smaller amino acid chains called Hydrolyzed collagens, which are more readily absorbed by the body. 
Hydrolyzed collagen can provide some of the building blocks our bodies need to make collagen (or other proteins).

Hydrolyzed collagen is a group of peptides with low molecular weight (3–6 KDa) that can be obtained by enzymatic action in acid or alkaline media at a specific incubation temperature. 
Hydrolyzed collagen can be extracted from different sources such as bovine or porcine. 

These sources have presented health limitations in the last years. 
Recently research has shown good properties of the Hydrolyzed collagen found in skin, scale, and bones from marine sources. 

Type and source of extraction are the main factors that affect Hydrolyzed collagen properties, such as molecular weight of the peptide chain, solubility, and functional activity. 
Hydrolyzed collagen is widely used in several industries including food, pharmaceutical, cosmetic, biomedical, and leather industries. 

The present review presents the different types of Hydrolyzed collagen, sources of extraction, and their applications as a biomaterial.
Hydrolyzed collagen is collagen that’s been broken down into more easily dissolvable amino acids, often available as a collagen powder dietary supplement. 

Hydrolyzed collagen is the most abundant—and some would say the most important—protein in the human body. 
Hydrolyzed collagen is made up of amino acids and can be found in our skin, bones, joints, muscles, hair, and nails.

Hydrolyzed collagen is a complex structural protein that maintains strength and flexibility throughout the body. 
Considered a vital structural building block, collagen is often compared to the scaffolding of a building: an invisible support system that holds the body together and keeps it strong. 

Hydrolyzed collagen also helps to keep our skin supple and young looking.
Hydrolyzed collagen contains low molecular weight peptides, produced by obtaining collagen via total hydrolysis.

Hydrolyzed collagen is an excellent dietary supplement, characterized by a combination of 18 major amino acids, with the highest concentration of glycine, proline and hydroxyproline. 
Hydrolyzed collagen is easily digested, quickly absorbed and distributed to the human body.

Hydrolyzed collagen can be offered in a variety of grades and forms, which are virtually tasteless and odorless, allowing it to be easily added to food, beverages and nutraceutical applications like nutrition bar, sports drinks, solid drinks, functional food, collagen tablets, cosmetics, etc.
Hydrolyzed collagen is a high molecular functional protein.

The main form of Hydrolyzed collagen absorption by the body is not amino acids but in the form of Hydrolyzed collagens.
Hydrolyzed collagen is highly digestible. 

The small intestine is absorbed by the small intestine, and finally enters the human blood circulatory system, organs, and cell tissues, and quickly exerts its physiological and biological functions. 
International studies on collagen have concluded that when the average small molecular weight of collagen is about 1,000, it is most conducive to human body absorption.

Hydrolyzed collagens are widely used in nutrition bars, sports drinks, solid drinks, functional food, collagen tablets, Cosmetics, etc.
Hydrolyzed collagen now is widely used in the field of dietetics in the manufacture of cereal bars, energy drinks, dietary supplements, etc and can often in combination with vitamins and minerals to enhance nutrition.

Hydrolyzed collagen is one of the top supplements on the market today. 
Found in bone, skin, muscle, tendons, and tissue, Hydrolyzed collagen is the amplest protein in our bodies. 

This substance plays a major part in our keeping our skin strong, strengthening muscles and joints, and repairing body tissue. 
As we age, our bodies lose collagen—though aging itself does not cause this depletion. Collagen is lost because of our exposure to pollutants, smoking, and overexposure to UV light.

Hydrolyzed collagen is the support element of skin, muscle, bone and joint structure. 
Hydrolyzed collagen is one of the most abundant proteins in our body and holds living tissue together. 

This primary connective tissue protein, which provides the infrastructure of the musculoskeletal system, is essential for mobility. 
Hydrolyzed collagen, which makes up 70% - 80% of our skin weight, is responsible for the structure, flexibility and moisture balance of the skin. 

Strong Hydrolyzed collagen structure is the most important factor in preventing wrinkles. 
Hydrolyzed collagen is a protein found in the body of all animals, including humans. 

Hydrolyzed collagen makes up connective tissue, such as skin, tendons, cartilage, organs, and bones.
When collagen is hydrolyzed, Hydrolyzed collagen’s broken down into smaller, easy-to-process particles. 

Those particles are used in products designed to heal everything from skin on the outside to joint pain on the inside.
Hydrolyzed collagen, also known as Hydrolyzed collagen or collagen hydrolysate, is a type of collagen that can be easily absorbed into the bloodstream when it's used as a supplement.1

In recent years, HC supplements have grown in popularity among people seeking to give their skin a more youthful appearance, alleviate joint pain, or improve bone health. 
Hydrolyzed collagen has also been used in clinical trials as a supplement for the promotion of wound healing after a burn.2

However, the use of collagen supplements is not without controversy. 
There is a lack of regulation over the quality or quantity of ingredients in over the-counter collagen supplements, as there is minimal peer-reviewed literature supporting its benefits.

Hydrolyzed collagens are bioactive. 
That means, once absorbed into the bloodstream, they can influence the activity of cells in the body in multiple ways. 

For example, Hydrolyzed collagens can stimulate fibroblasts in the skin to make more hyaluronic acid, which is essential for skin hydration.
Hydrolyzed collagen is a protein consisting of amino acids. 

Hydrolyzed collagens benefits to human health have been known since ancient times. 
For centuries, humans have produced and consumed collagen by preparing bone broth to protect bone and joint health. 

Hydrolyzed collagen is obtained by separation of buildings blocks of collagen through enzymes. 
Hydrolyzed collagen and gelatine are proteins obtained from collagen and contain amino acids. 

But, Hydrolyzed collagens are small molecules produced by enzyme hydrolysis and have a molecular weight lower than gelatine. 
Hydrolyzed collagens have no gelling effect such as gelatine and are soluble in cold water. 

Thanks to Hydrolyzed collagens proved benefits to health, Hydrolyzed collagen is used in functional food and supplementary diet nutrition.
Hydrolyzed collagens are very small pieces of protein from animal collagen. 

Hydrolyzed collagen is one of the materials that makes up cartilage, bone, and skin.
Hydrolyzed collagens are made by breaking down whole collagen proteins into smaller pieces. 

When taken by mouth, Hydrolyzed collagens seem to build up in the skin and cartilage. 
This might help improve some skin and joint conditions.

Hydrolyzed collagens are used for aging skin and osteoarthritis. 
Hydrolyzed collagens are also used for osteoporosis, brittle nails, muscle strength, and many other purposes, but there is no good scientific evidence to support most of these uses.

Hydrolyzed collagen is not a uniform substance, but is rather a family of protein. 
Hydrolyzed collagen is a group of naturally occurring proteins.  

For food or nutritional purpose, collagen is broken down into gelatine which can be broken down further into hydrolysed collagen. 
Hydrolysed collagen is a polypeptide composite made by further hydrolysis of denatured collagen or gelatin and the molecular weights are within the range approximately 500 to 25000 Da. 

In hydrolysate, the molecular mass and the size of the molecules have been deliberately decreased by hydrolysis part of peptide bonds of the gelatine molecules. 
This will make the hydrolysed collagen dissolved in cold water and does not gel anymore but still has surface active properties. 

The processes involved in processing hydrolysed collagen are demineralization, extraction of collagen to gelatine, enzymatic hydrolysis to obtain hydrolysed collagen, ion exchange, filtration, evaporation, sterilization and  finally drying.
Hydrolyzed collagen supplements are most commonly derived from bovine, marine animals and chicken. 

This means that if you’re allergic to beef, fish or poultry, you could have a reaction after consuming collagen supplements.
Hydrolyzed Collagen Protein is a nutritious dairy-free protein powder made from a highly concentrated bone broth isolate. 
The protein is sourced from hormone-free, antibiotic-free, non-GMO cows in Sweden, is ideal for dairy-sensitive patients and those who desire a collagen source of protein.

Hydrolyzed Collagen Powder is indicated for use in the management of chronic and acute wounds, including partial- and full-thickness wounds, pressure injuries, traumatic wounds, diabetic ulcers, first- and second-degree burns, venous stasis ulcers and arterial ulcers. 
Hydrolyzed collagen Uses the powder on moderately to heavily exudative wounds.


Hydrolyzed Collagen is the most prevalent type of protein in our bodies, making Hydrolyzed Collagen a powerful supplement that can directly support our skin, bone, tendons and muscle structures.
Although Hydrolyzed Collagen is the most abundant protein in the body, used in muscle, ligaments, cartilage, bone, skin and blood, we stop producing as much of Hydrolyzed collagen naturally as we age. 
Supplementing Hydrolyzed Collagen into your daily regimen will help improve your health in a variety of ways. 
 

 

USES:

Hydrolyzed collagen is the most abundant and ubiquitous protein in animal origin, which comprising approximately 30% of total protein.
Hydrolyzed collagen is mainly presents in all connective tissues, including animal skin, bone, cartilage, tendon and blood vessels.

Hydrolyzed collagen is involved in the formation of fibrillar and microfibrillar networks of the extracellular matrix and basement membranes.
Hydrolyzed collagen forms great tensile strength and stable insoluble fibrils, contributing to the stability and structural integrity of tissues and organs.

Hydrolyzed collagen is the most abundant protein in your body.
Hydrolyzed collagen gives your skin strength and elasticity. 

Referred to as the ‘youth protein’, collagen accelerates the turnover of skin cells and provides support to the structure of your skin.
Maximizing the collagen in your skin will keep it smooth, plump, and wrinkle-free. 

Hydrolyzed collagen masks are designed to boost your skin’s collagen content and slow down collagen degradation.
Hydrolyzed collagen, being an emulsifier, without smell and taste is used mainly in food, medicine and cosmetics industries. 

Hydrolyzed collagen smooths out the skin, makes the hair shine, strengthens the nails, strengthens the muscles and fights with osteoporosis while increasing the bone density. 
Hydrolyzed collagen is an important constituent of our body and is indispensable for the daily life.

 


-Cellular activity assays

-Used in generation of dorsal root ganglion (DRG) explant cultures

-Used as one of the components during the preparation of the functionalized surface (in NMR setup)

-Used in cell culture (the glass coverslips were coated with nanowires at high concentrations mixed with collagen)

-Used for biofunctionalization of the microchannels

-a healthier life 

-more beautiful skin 

-being fit

-good joint 

-bone health

 

 

APPLICATIONS:


-nutrition bar 

-sports drinks 

-solid drinks 

-functional food

-collagen tablets 

-cosmetics

 

 


BENEFITS:


-Skin anti-aging

-Bone and joint health

-Wound healing

-Body composition

-Solidifies the joints.

-Renews the cartilages.

-Increases bone intensity.

-Enforces muscles.

-Tightens the skin, increases elasticity.

-Strengthens hair due to creation of keratin.

-Enforces teeth and nails.

-Provides fragments to the wound bed that are a fraction of the size of native collagen

-Maintains a moist wound environment conducive to healing

-Conforms to any wound bed, including tunneling and undermining wounds

-Preservative- and synthetic-free, safe and non-toxic

-Easy to apply

-Aids in joint health and longevity

-Increases muscle recovery

-Reduces workout soreness

-Promotes skin elasticity and youthfulness

-Reduces skin wrinkles and the appearance of aging

-Helps reduce the appearance of cellulite

-Improves overall digestive health

 


FUNCTIONS:


-Antistatic: Reduces static electricity by neutralizing electrical charge on a surface

-Emollient: Softens and smoothes the skin

-Film forming: Produces a continuous film on skin, hair or nails

-Hair conditioner: Leaves hair easy to comb, soft, soft and shiny and / or confers volume, lightness and shine

-Humectant: Maintains the water content of a cosmetic in its packaging and on the skin

-Skin conditioning: Keeps the skin in good condition

 


APPEARANCE:

White or off white powder

 


PROPERTIES:


-Quality Level: 200

-biological source: rat tail

-sterility: non-sterile

-product line: BioReagent

-form: powder

-packaging: glass bottle of 5 mg

-application(s): cell culture 

-surface coverage: 6‑10 μg/cm2

-solubility: 0.1 M acetic acid: 1 mg/mL (Allow to stir at room temperature 1-3 hours until dissolved.)

 


STORAGE:

Store in Hydrolyzed collagens package in a dry and cool place.
Store at room temperature and protect from freezing.

 


SYNONYM:

Colatron
Collagens, hydrolyzates
Crotein SPO
Gelita-Sol C
Hydrolyzed animal protein
Hydrolyzed collagens
Lexein X 350
Marine Matrix
Norlan LVC
Peptide PRA
Protein hydrolysate from collagen
Protein hydrolyzates, collagen
Proteins, collagen, hydrolysate

 


IUPAC NAME:

N-[2-hydroxy-3-
(stearyldimethylammonio)propyl] 
hydrolyzed collagen
acetic acid
COLLAGENS
Collagens
Protein

 

 

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