HYDROLYZED HYALURONIC ACID

Hydrolyzed Hyaluronic Acid is used Deep hydration in serums, moisturizers, anti-aging creams, eye/lip balms; plumps fine lines and improves skin elasticity.
Hydrolyzed Hyaluronic Acid is used Conditioning agent, providing moisture retention and improved manageability.
Hydrolyzed Hyaluronic Acid is applied in cosmetics as antistatic or emollient ingredient for formulas.

CAS Number: 9004-61-9
EC No: 9004-61-9
Chem/IUPAC Name: Hydrolyzed Hyaluronic Acid
Molecular Formula: C₁₄H₂₁NO₁₁ (representing repeating disaccharide units; fragments typically low molecular weight, e.g., <10 kDa) 
Molecular Weight Range: Very low molecular weight fragments commonly <10 kDa (e.g. 5–50 kDa) for deeper skin penetration

SYNONYMS:
Hydrolyzed Hyaluronic Acid, Hydrolyzed Hyaluronate. Often referenced as the hydrolysate of Hyaluronic Acid (CAS 9004‑61‑9), Hyaluronic acid, Hyaluronic acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Hyaluronate

Hydrolyzed Hyaluronic Acid offers deep, long-lasting hydration that visibly firms and smooths the skin, reducing roughness by up to 66%.
By stimulating collagen and supporting cellular repair, Hydrolyzed Hyaluronic Acid strengthens skin’s defenses for a resilient, youthful appearance.

Hydrolyzed Hyaluronic Acid is produced by breaking down high‑molecular‑weight hyaluronic acid into smaller fragments via enzymatic or acid hydrolysis methods.
These low‑molecular‑weight fragments (typically 5–50 kDa or less) offer better skin penetration, increased hydration, and enhanced bioactivity compared to native HA.

Hydrolyzed Hyaluronic Acid functions as a humectant, skin-conditioning agent, and hair-conditioning agent in cosmetic formulations
Hydrolyzed Hyaluronic Acid is a derivative of hyaluronic acid broken into small molecular fragments designed for enhanced skin absorption.
Its excellent hydrating and skin-conditioning benefits make Hydrolyzed Hyaluronic Acid a staple in modern skincare, especially in anti-aging and moisturizing formulations.

With minimal safety concerns when used topically at appropriate concentrations and stable handling properties, Hydrolyzed Hyaluronic Acid’s trusted globally in cosmetics.
After hydrolysis through acidic or enzymatic means, large molecular chains of hyaluronic acid are formed into fragments of low molecular weight.

This includes a molecular weight usually between 1-50 kilodaltons (kDa), much lower in molecular weight when contrasted with unhydrolyzed hyaluronic acid.
Hydrolyzed hyaluronic acid with hyaluronic acid are said to be able to smooth wrinkles and firm the skin.

Hydrolyzed Hyaluronic Acid is considered a highly effective anti-ageing weapon, can plump up the skin from the inside and make it soft and supple.
This is why products containing Hydrolyzed Hyaluronic Acid are no longer a fashion trend, but an essential part of skin care.

However, how well Hydrolyzed Hyaluronic Acid actually works depends largely on the type of hyaluronic acid used, as science recognizes several different types.
These differ chemically in terms of the different lengths of the molecular chains and the size of the molecules.

Hydrolyzed Hyaluronic Acid is of particular interest.
Hydrolyzed Hyaluronic Acid is a substance produced naturally in the body and behaves like a sponge in our organism, as it is able to bind up to 1000 times its own weight in water.

Although there are different molecular weights, Hydrolyzed Hyaluronic Acid is unfortunately not yet possible to reliably determine this on the basis of the INCI list.
High-molecular hyaluronic acid with a molecular weight of more than 500 kDa is a very good surface moisturizer.

It serves as a skin protectant and is able to act as an osmotic pump, which means that it can help water-soluble active ingredients to penetrate the skin.
Low-molecular hyaluronic acid has a molecular weight of less than 500 kDa and can therefore moisturize the skin somewhat more deeply.

Nevertheless, it is a relatively large molecule, which means that it mainly acts in the outer layer of our skin (epidermis).
In an interesting study, low-molecular hyaluronic acid with a molecular weight of just 200 kDa was used.
It was found that it can help the skin to repair itself by specifically strengthening its self-defense.

Hydrolyzed Hyaluronic Acid is a type of HA that has been hydrolyzed or broken down, into individual molecules of glucose and uronic acid.
This makes the HA more soluble, so Hydrolyzed Hyaluronic Acid can be better absorbed by the body.
Hydrolyzed Hyaluronic Acid also makes it less viscous, or thick, so it can be used in topical applications like cosmetics and skincare products.

Hydrolyzed Hyaluronic Acid is thought to be more effective than regular HA at promoting collagen production, wound healing, and skin hydration.
A popular misconception in the skincare industry is that more active ingredients = more potent formulas, but this is not always the case.
Why?

Because no matter how many incredible actives you pack into a formula, it may ultimately amount to very little transformation in the skin without an optimal delivery system i.e. the formula’s method of penetrating the skin in order to enact real change upon target cells.
This is why molecular weight is incredibly important.

Enter Hydrolyzed Hyaluronic Acid…
Hydrolyzed Hyaluronic Acid is a revolutionary active ingredient that offers numerous benefits for epidermis within a hyaluronic acid moisturiser.

With an average weight of 50kDa, Hydrolyzed Hyaluronic Acid is produced through a gentle thermal degradation method, resulting in a lower molecular weight than hyaluronic acid.
This fragmentation enhances Hydrolyzed Hyaluronic Acid's ability to penetrate the skin, leading to improved hydration for dry skin rejuvenation, increased elasticity, reduction in skin texture, and diminished wrinkles.

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid that has been broken down into smaller molecules which contributes to its absorption into the skin.
Hydrolyzed Hyaluronic Acid is a highly potent humectant that draws moisture into the skin, providing deep hydration and plumping effects.

Unlike regular hyaluronic acid, Hydrolyzed Hyaluronic Acid can penetrate deeper into the skin layers due to its smaller molecular size.
Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid that has been broken down into smaller molecules which contributes to its absorption into the skin.

Hydrolyzed Hyaluronic Acid is an extremely hydrophilic complex sugar, naturally present in the human body in the joints, muscles, eyes and especially in the skin.
Nearly 50% of Hydrolyzed Hyaluronic Acid's total quantity is found in the dermis, the deep layer of the skin.

Hydrolyzed Hyaluronic Acid constitutes the extracellular matrix and serves as a support for collagen and elastin fibers.
Hydrolyzed Hyaluronic Acid also ensures the hydration of the skin because it acts like a molecular sponge: it captures water molecules and retains them.

Nevertheless, as the years go by, the body's production of hyaluronic acid tends to decrease (a drop of about 6% per decade), which leads to skin slackening, the appearance of the first wrinkles and a decrease in cellular activity.
From the age of 50, Hydrolyzed Hyaluronic Acid has been proven that the stock of hyaluronic acid is divided by two.

Faced with this observation, Hydrolyzed Hyaluronic Acid is particularly interesting to provide the skin with hyaluronic acid via dermocosmetic application.
Indeed, this is less invasive and therefore much less risky than injections!

Hydrolyzed Hyaluronic Acid in cosmetics is a derivative of hyaluronic acid, a natural component of skin known for its exceptional hydrating properties.
Hydrolyzed Hyaluronic Acid is in a more refined form with smaller molecules for better absorption.

Hydrolyzed Hyaluronic Acid greatly enhances moisture retention, promoting smoother, plumper skin.
Renowned for its ability to attract and retain water molecules, Hydrolyzed Hyaluronic Acid is a key ingredient in skincare products, including serums and moisturizers.

Hydrolyzed Hyaluronic Acid's smaller molecular size ensures deep penetration, making it effective in revitalizing and hydrating the skin at a cellular level.
Hydrolyzed Hyaluronic Acid is a small molecule of Hyaluronic Acid (HA), with molecular weight in the range 37k-56kDa.

 
USES and APPLICATIONS of HYDROLYZED HYALURONIC ACID:
Skin care: Hydrolyzed Hyaluronic Acid is used Deep hydration in serums, moisturizers, anti-aging creams, eye/lip balms; plumps fine lines and improves skin elasticity
Hair care: Hydrolyzed Hyaluronic Acid is used Conditioning agent, providing moisture retention and improved manageability

Humectant: Hydrolyzed Hyaluronic Acid binds moisture to the skin surface and higher dermal layers; enhances barrier function and texture
Antistatic agent: Hydrolyzed Hyaluronic Acid is applied in cosmetics as antistatic or emollient ingredient for formulas
Hydrolyzed Hyaluronic Acid is a highly potent humectant that draws moisture into the skin, providing deep hydration and plumping effects.

Unlike regular hyaluronic acid, Hydrolyzed Hyaluronic Acid can penetrate deeper into the skin layers due to its smaller molecular size.
Hydrolyzed hyaluronic acid is hyaluronic acid that has gone through the process of hydrolysis, which involves changing an ingredient from one form to another by the addition of water or enzymes.

In this case, Hydrolyzed Hyaluronic Acid results in a form of hyaluronic acid with a lower molecular weight, meaning it can more readily penetrate skin (pure hyaluronic acid is a large molecule).
That lower molecular weight results in increased hydration in skin’s surface layers.

This doesn’t mean that hydrolyzed hyaluronic acid is better than non-hydrolyzed hyaluronic acid, simply that it works differently.
Hydrolyzed Hyaluronic Acid’s good to use multiple forms of hyaluronic acid (including the more bio-available sodium hyaluronate) to make sure your skin care routine is as robust as possible.

Usage levels of hydrolyzed hyaluronic acid in skin care typically range from 0.1–0.5%.
Hydrolyzed Hyaluronic Acid has not only good moisturizing property, but also activities such as transdermal absorption capability, nourishing the skin deeply, etc.
Hydrolyzed Hyaluronic Acid can restore youthful skin by withholding water, improving skin elasticity and decreasing skin wrinkles.

HOW IS HYDROLYZED HYALURONIC ACID USED IN PRODUCTS?
Hydrolyzed Hyaluronic Acid is included for its plumping, hydrating, and skin-renewal benefits and for its ability to penetrate the skin deeply and provide intense hydration.
Hydrolyzed Hyaluronic Acid can plump, hydrate, and protect the skin.

*Fragmentation and Penetration Enhancement.
The breakthrough lies in the fragmentation of large HA polymers through a chemical process called hydrolysis.
This process significantly improves the penetration ability of hyaluronic acid into the deeper layers of skin.
By reducing the molecular weight, hydrolysed hyaluronic acid overcomes the limitations of traditional HA and unlocks its full potential.

FUNCTIONS (INCI) of HYDROLYZED HYALURONIC ACID:
*Hair conditioning : 
Hydrolyzed Hyaluronic Acid leaves hair easy to comb, soft, soft and shiny and / or confers volume, lightness and shine

*Humectant : 
Hydrolyzed Hyaluronic Acid maintains water content of a cosmetic both in its packaging and on the skin

*Skin conditioning : 
Hydrolyzed Hyaluronic Acid maintains skin in good condition

HYDROLYZED HYALURONIC ACID IS PRESENT IN:
Hydrolyzed Hyaluronic Acid is present in 1.09% of cosmetics.
*Cc cream (11.53%)
*Anti-aging eye contour care (7.36%)
*Day anti-ageing face serum (6.8%)
*Face moisturizing serum (6.23%)
*Eye contour care (5.4%)

WHAT ARE THE BENEFITS OF HYDROLYZED HYALURONIC ACID?
*MOISTURIZING.
*REJUVENATING.
*PROTECTING.

*Moisturizing: 
Hydrolyzed Hyaluronic Acid provides deep hydration by penetrating the skin’s layers, which can maintain moisture levels.

*Rejuvenating: 
Hydrolyzed Hyaluronic Acid contributes to skin elasticity and suppleness, minimizing the appearance of maturing skin.

*Smoothing: 
Hydrolyzed Hyaluronic Acid contributes to skin texture and smoothness, giving the skin a plumper and more youthful look.

*Protecting: 
Hydrolyzed Hyaluronic Acid promotes skin barrier function, which can protect from environmental factors and dehydration.

*Gentle: C
Hydrolyzed Hyaluronic Acid cn soothe and calm irritated or sensitive skin, promoting a more even complexion.