PRODUCTS

HYDROXYACETIC ACID

Hydroxyacetic Acid is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroxyacetic Acid has a role as a metabolite and a keratolytic drug.
Hydroxyacetic Acid is a 2-hydroxy monocarboxylic acid and a primary alcohol.

CAS NUMBER: 79-14-1

EC NUMBER: 201-180-5

MOLECULAR FORMULA: HOCH2COOH

MOLECULAR WEIGHT: 76.05

IUPAC NAME: 2-hydroxyacetic acid

Hydroxyacetic Acid (or Glycolic acid; chemical formula HOCH2CO2H) is a colorless and hygroscopic crystalline solid
Hydroxyacetic Acid is odorless

Hydroxyacetic Acid is highly soluble in water.
Hydroxyacetic Acid is used in various skin-care products.

Hydroxyacetic Acid is widespread in nature.
Hydroxyacetic Acid is a salt or ester of glycolic acid.

Hydroxyacetic Acid is functionally related to an acetic acid.
Hydroxyacetic Acid is a conjugate acid of a glycolate.

Preparation of Hydroxyacetic Acid:
Hydroxyacetic Acid can be synthesized in various ways.
The predominant approaches use a catalyzed reaction of formaldehyde with synthesis gas (carbonylation of formaldehyde), for its low cost.

Hydroxyacetic Acid is also prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.
Other methods, not noticeably in use, include hydrogenation of oxalic acid, and hydrolysis of the cyanohydrin derived from formaldehyde.
Some of today's Hydroxyacetic Acids are formic acid-free.
Hydroxyacetic Acid can be isolated from natural sources, such as sugarcane, sugar beets, pineapple, cantaloupe and unripe grapes.
Hydroxyacetic Acid can also be prepared using an enzymatic biochemical process that may require less energy.

Properties:
Hydroxyacetic Acid is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.
The carboxylate group can coordinate to metal ions forming coordination complexes.

Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.

Hydroxyacetic Acid is used in the textile industry as a dyeing and tanning agent.
Hydroxyacetic Acid (or Glycolic acid) is the smallest alpha-hydroxy acid (AHA).

This colorless, odorless, and hygroscopic crystalline solid is highly soluble in water.
Due to its excellent capability to penetrate skin, Hydroxyacetic Acid finds applications in skin care products, most often as a chemical peel.

Hydroxyacetic Acid may reduce wrinkles, acne scarring, hyperpigmentation and improve many other skin conditions, including actinic keratosis, hyperkeratosis, and seborrheic keratosis.
Once applied, Hydroxyacetic Acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.

This allows the outer skin to dissolve revealing the underlying skin.
Hydroxyacetic Acid is a metabolite found in or produced by Escherichia coli

Hydroxyacetic Acid is 2-hydroxy monocarboxylic acid
Hydroxyacetic Acid is acetic acid where the methyl group has been hydroxylated.

Hydroxyacetic Acid is used in various skin-care products.
Hydroxyacetic Acid is widespread in nature.

Hydroxyacetic Acid is a salt or ester of glycolic acid.
Hydroxyacetic Acid is the smallest organic molecule from the alpha-hydroxy carboxylic acids family.

Hydroxyacetic Acid's chemical name is hydroxyacetic acid that naturally occurs in sugarcane, beets, grapes, and fruits.
Hydroxyacetic Acid's small molecule size, low molecular weight, and dual functional groups (COOH & OH) make it an excellent choice for cleaning formulations and a safer alternative to hazardous acids in a wide range of consumers and industrial cleaning products.

Hydroxyacetic Acid is the smallest alpha-hydroxy acid.
Hydroxyacetic Acid is mainly supplemented to various skin-care products to improve the skin’s appearance and texture.

Hydroxyacetic Acid can also reduce wrinkles, acne scarring, and hyperpigmentation.
In textile industry, Hydroxyacetic Acid can be used as a dyeing and tanning agent.

Hydroxyacetic Acid can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry.
Hydroxyacetic Acid can also be added into emulsion polymers, solvents and ink additives to improve flow properties and impart gloss.

Moreover, Hydroxyacetic Acid is a useful intermediate for organic synthesis including oxidative-reduction, esterification and long chain polymerization.
Hydroxyacetic Acid is also known as hydroxyacetic acid

APPLICATIONS:
*skin-care products
*textile industry
*as a dyeing
*tanning agents
*as a flavoring agent
*food processing
*skin care agent
*pharmaceutical industry
*emulsion polymers
*solvents
*ink additives
*intermediate for organic synthesis
*oxidative-reduction
*esterification and long chain polymerization
*in dyeing
*in tanning
*in electropolishing
*in foodstuffs
*textiles
*leather industry
*manufacture of adhesives
*copper brightening
*decontamination cleaning
*electroplating
*chemical milling of metals

Hydroxyacetic Acid is composed of colorless deliquescent leaflets that decompose at approximately 78° C (172 OF).
Hydroxyacetic Acid is soluble in water,alcohol and ether.

Hydroxyacetic Acid is used in dyeing, tanning, electropolishing,and in foodstuffs.
Hydroxyacetic Acid is produced by oxidizing glycol with dilute nitric acid.

Hydroxyacetic Acid is used in the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives
Hydroxyacetic Acid is used in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals.

PHYSICAL PROPERTIES:

-Molecular Weight: 76.05

-XLogP3: -1.1

-Exact Mass: 76.016043985

-Monoisotopic Mass: 76.016043985

-Topological Polar Surface Area: 57.5 Å²

-Physical Description: Colorless, odorless crystals

-Color: Colorless

-Form: Translucent solid

-Odor: Odorless

-Boiling Point: 100 °C

-Melting Point: 79.5 °C

-Solubility: Soluble in ethanol, ethyl ether

-Density: 1.49

-Vapor Density: 2.6

-Vapor Pressure: 0.02 mmHg

-LogP: -1.11

-Corrosivity: Corrosive

Hydroxyacetic Acid reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles.
Hydroxyacetic Acid acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells.

Hydroxyacetic Acid also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water.
As a result, the skin’s own ability to raise its moisture content is increased.

CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 2

-Hydrogen Bond Acceptor Count: 3

-Rotatable Bond Count: 1

-Heavy Atom Count: 5

-Formal Charge: 0

-Complexity: 40.2

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Other Classes -> Organic Acids

Hydroxyacetic Acid is the simplest alpha hydroxyacid.
Hydroxyacetic Acid is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight.

Hydroxyacetic Acid proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes.
Hydroxyacetic Acid is also used for diminishing the signs of age spots, as well as actinic keratosis.

However, Hydroxyacetic Acid is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles.
Regardless of the skin type, Hydroxyacetic Acid use is associated with softer, smoother, healthier, and younger looking skin.
Hydroxyacetic Acid is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations

Hydroxyacetic Acid's chemical formula is HOCH2CO2H
Hydroxyacetic Acid is a colorless and hygroscopic crystalline solid

Hydroxyacetic Acid is odorless
Hydroxyacetic Acid is used in various skin-care products.

Hydroxyacetic Acid is a conjugate acid of a glycolate.
Hydroxyacetic Acid is used in the textile industry as a dyeing and tanning agent.

Hydroxyacetic Acid is a metabolite found in or produced by Escherichia coli
Hydroxyacetic Acid is used in various skin-care products.

Hydroxyacetic Acid can be used as a dyeing and tanning agent.
Hydroxyacetic Acid can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry.

Hydroxyacetic Acid is also known as hydroxyacetic acid
Hydroxyacetic Acid is soluble in water,alcohol and ether.

Hydroxyacetic Acid is used in dyeing, tanning, electropolishing,and in foodstuffs.
Hydroxyacetic Acid is used in the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives
Hydroxyacetic Acid is used in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals.

SYNONYMS:

glycolic acid
2-Hydroxyacetic acid
hydroxyacetic acid
79-14-1
Glycollic acid
Hydroxyethanoic acid
Acetic acid, hydroxy-
glycolate
Glycocide
alpha-Hydroxyacetic acid
Kyselina glykolova
Kyselina glykolova
Kyselina hydroxyoctova
HOCH2COOH
2-Hydroxyethanoic acid
Kyselina hydroxyoctova
Polyglycolide
Acetic acid, 2-hydroxy-
.alpha.-Hydroxyacetic acid
GLYCOLLATE
glycolicacid
EINECS 201-180-5
Hydroxyethanoate
a-Hydroxyacetate
CCRIS 9474
hydroxy-acetic acid
2-Hydroxyaceticacid
alpha-Hydroxyacetate
a-Hydroxyacetic acid
Glycolic Acid 70%
2-hydroxy acetic acid
2-hydroxy-acetic acid
2-hydroxyl ethanoic acid
HO-CH2-COOH
Hydroxyacetic acid solution
EC 201-180-5
4-03-00-00571
Acetic acid, hydroxy- (9CI)
HYDROXYACETIC ACID
CAS-79-14-1
HYDROXYACETIC ACID
HYDROXYETHANOIC ACID
Hydroxyacetic acid
Hydroxyethanoic acid
Glycollic acid
Glycolic Acid
2-Hydroxyacetic acid
2-Hydroxyethanoic acid
α-hydroxyacetic acid
alpha-Hydroxyacetic acid
Glycolic acid
GLYCOLIC ACID
Glycollic acid
HOCH2COOH
Hydroxyacetic acid
Hydroxyethanoic acid
2-HYDROXYACETIC ACID
GLYCOLATE
glycolic
HYDROXYACETIC ACID
HOCH2COOH
GLYCOLLIC ACID
Glycolic acid 70%
glycolate (hydroxyacetate)