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CAS NUMBER: 1340-06-3
EC NUMBER: 215-671-7
Ichthyol has a softening, soothing, mild antiseptic and abscess maturing feature as a skin care product.
Ichthyol helps the main treatment in the wound care of cattle, sheep, horses and dogs by removing the oily crust, dry crust and follicle crusts formed on their skin.
Ichthyol relieves itching and accelerates the treatment of animals by maturing abscesses quickly.
Ichthyol is applied as an emollient on the skin of the breasts in mastitis.
Ichthyols active ingredient is ichthyol.
Ichthyol can be used as a local antiseptic or in the treatment of inflammatory diseases.
Ichthyol exhibits anti-inflammatory and anti-microbial properties.
Ichthyol shows good tolerance, multilateral application, reduces dandruff, is effective against skin impurities, reduces irritations and itching and reduces excessive sebum production.
Ichthyol is used in anti-dandruff shampoos, clear and pearly luster effect formulations, cream rinses, hair coloring and perms.
Ichthyol is also used in body lotions, after showering, after shaving, after depilating, facial care (pimples), cleansing milks, cream, after tanning- and after sun-products.
Ichthyol has high grade active ingredients, decades of experience and highest quality standards have made our independent, family-owned pharmaceutical company to one of the most important suppliers of therapeutics in dermatology and orthopaedics.
Ichthyol has the distinction of being manufacturer of own active ingredients made from natural oil shale rock.
For this purpose oil shale rock with a high content of sulphur that is indispensable for efficacy is exploited in our mine in France in a sophisticated system of underground chambers.
Ichthyol is a product of natural origin obtained in the first step by dry distillation of sulfur-rich oil shale.
By sulfonation of the resulting oil, and subsequent neutralization with ammonia, Ichthyol results as a viscous, water-soluble substance with a characteristic bitumen-like odor.
Ichthyol is used in medicine (sometimes in combination with zinc oxide) as a treatment for different skin diseases, including eczema and psoriasis.
Ointments containing 10% or 20% Ichthammol are most common.
Ichthyols are sometimes called "black ointments" or "drawing salves".
Though Ichthyol is naturally present at the skin level, in some cases Ichthyol can excessively multiply.
Ichthyols bring to normal levels the sebum secretion, as well as the renewal rate of epidermal cells at the scalp level, eliminating the unpleasant and unaesthetic effects of dandruff.
Ichthyol can be also used to improve more unpleasant problems, such as seborrheic dermatitis.
Ichthyols revolutionary formula is based on ingredients such as Piroctone Olamine, an essential anti-fungal solution in fighting dandruff, ichthyol, with anti-inflammatory and anti-septic properties, and Pro-Vitamin B5, which maintains an optimum hydration both of the scalp and of the hair.
Ichthyol creates unfavorable conditions for the spread of the microorganisms and forces dirt out to the surface, thus preventing the formation of unwanted and painful acne in the deeper layers of the skin.
Ichthyol strengthens the skin’s natural protective barrier and stimulates its regeneration processes without causing allergic reactions.
Ichthyol has high permeability and the ability to regulate moisture balance and mechanisms related to the sebaceous gland’s activity, as well as skin regeneration processes.
Ichthyol enhances the effect of other active ingredients, helping them penetrate the deeper layers of the skin.
Ichthyol is used for the treatment of boils and skin infections (cysts) in various animals.
Ichthyol is an anti-microbial.
Ichthyol is a dark sulfonated shale oil obtained via the sulfation and ammoniation of a mineral deposit distillate (shale oil).
Ichthyols various constituents include saturated and unsaturated hydrocarbons, nitrogen bases, acids, and thiophene derivatives.
USAGE:
Ichthyol is for external use. Before using Royal Ichthyol Pomade, the area to be applied should be washed with soap and water and dried.
Ichthyol is applied as a thin layer several times a day for 3-4 days.
Ichthyol is repeated when necessary.
-Human:
Ichthyols are classified as local therapeutic agents with very good tolerability.
Ichthammol does not have any corrosive properties on the skin.
Ichthyol should not be confused with “black ointment” or “drawing salve.”
The latter are typically ichthammol-containing ointments used for skin conditions including psoriasis and eczema.
They are not meant to be escharotics.
Pharmacologically, Ichthammol has anti-inflammatory, bactericidal, and fungicidal properties.
Ichthyol is used to treat a variety of skin disorders.
In otology, a mixture of glycerol and ichthammol is used for the topical treatment of ear infections.
Ichthyol is effective against Gram-positive bacteria.
The anti-inflammatory action is explained by its influence on the formation, secretion, and effect of inflammation mediators.
Ichthammol is available in pharmacies for compounding medications.
Different sources of information exist for exemplary formulations.
According to the "list of preferred Specials" by the British Association of Dermatologists (BAD) Ichthammol can be used in dermatology prescribing to treat acutely inflamed atopic eczema, among others.
A corresponding recommendation exists for bituminosulfonates in Germany.
According to “guideline atopic eczema” bituminosulfonates can be considered for treatment of atopic eczema based on general clinic experience.
In the European Dermatology Forum (EDF) guidelines for treatment of atopic eczema Ichthammol is recommended as a useful addition to the basic treatment regimen, especially in mild disease or if TCS treatment is not possible from a patient’s perspective, e.g. corticophobia.
COMPOSITION:
From elemental analysis, the composition of Ichthammol was calculated to be C28H36S5O6(NH4)2.
However, as a product of natural origin, Ichthyol is a mixture of many different compounds.
Chemically, Ichthyol is a sulfonated shale oil that is incompatible with acids, alkali carbonates or hydrates and alkaloidal salts.
Ichthyol is a thick reddish brown liquid, possessing a bituminous odor and taste.
Ichthyol is soluble in water and miscible with glycerin, but is nearly insoluble in strong alcohol or concentrated ether.
Ichthyol contains a large percentage of organically combined sulfur.
DOSAGE:
Wash the affected area with lukewarm water and soap, then dry and massage the ointment well.
STORAGE:
Store in a cool, dry and dark place at a temperature not exceed 30° C.
COMPOSITION:
Each 1g contains:
-Ichthyol 200 mg
-Excipients ad 100 g
Ichthyol preparations are characterized chemcally by their richness in sulphur, so intimately united that it can only be extracted by complete decomposition (Lartigeau); they easily take up oxygen, acting as powerful reducing agents.
Ichthyol offers for new and innovative cosmetics.
Due to Ichthyols broad spectrum of efficacy the well tolerated substance of natural origin can be used in hair care products and for skin care as well (e.g. for treatment of skin blemishes, redness or itching).
In the following some detailed technical and scientific information on origin, properties, efficacy and tolerance of Ichthyol is given for all those involved in development work with this unique substance.
BENEFITS:
-anti-microbial
-anti-inflammatory
-anti-seborrheic
-anti-itching
DEFINITION:
Ichthyol is the sodium salt of a pale sulfonated shale oil inaqueous solution.
IDENTIFY:
- formation of a precipitate by addition of hydrochloric acid
- detection of sodium
- detection of sulfur
PURITY:
- pH-value (1% aq. Solution): 6.0 - 7.5
- sulfated ash: max. 15 %
- refractive index: 1.44 - 1.46
- relative density: 1.15 - 1.25
SOLUBILITY:
- soluble in water, miscible with glycerol, partly soluble in alcohol and ether
ODOUR:
-weak and characteristic
COLOUR:
-in thin layer light-brown, in thick layer dark-brown
SPECIFICATION:
Aqueous solutions containing 2% of Ichthyol as well as the pure (undiluted) substance were subjected to a microbiological analysis.
According to this impurity test the number of germs (microbial count of fungi and bacteria) present in the watery solution of Ichthyol as well as the pure substance is below the detection limit (< 10/g).
No aerobic bacteria could be detected.
The antimicrobial effect of Ichthyol helps maintain the microbiological stability of formulations and lessens the amount of preservatives required.
As a sulfonate salt Ichthyol has tensio-active properties (lipophilic (R) and hydrophilic part (SO3Na) in the molecule).
As a consequence, there may be possible
In general, hydrophilic creams are favoured compared to lipophilic creams.
In case of liquefaction hydrophilic creams containing Ichthyol can be stabilized by addition of hydroxyethylcellulose, for instance.
Ichthyol is stable in a wide range of pH.
Only with strong acids precipitation may result.
Ichthyol is the sodium salt of a sulfonated low-boiling shale oil fraction in aqueous solution.
The general designation is ‘pale sulfonated shale oil’.
Ichthyol consists of polar sulfonate salts with a high content of organically bound sulfur.
To understand more about the chemical composition of Ichthyol its origin and manufacture have to be considered.
The origin of Ichthyol goes back to deposits of phytoplankton in a special lagoonal setting in the region of the alps in the Mesozoic era.
Ichthyol has a lot to offer cosmetic formulations due to multi-functionality combined with natural origin and good tolerance.
At the same time, Ichthyol has a soothing effect on the scalp.
Ichthyol is relieved.
The consumer benefits here from the anti-oxidative and anti-inflammatory properties of ICHTHYOL® PALE
PH:
The pH is measured potentiometrically in an aqueous solution containing 1% of substance (m/m).
BENEFITS:
-Provision of valuable additional actions
-Exceptional anti-dandruff performance
-Faster and broader effects
-Symptoms concomitant to dandruff are successfully countered
-Better tolerance
-Reduction of original active ingredient concentration
FUNCTION:
-anti-seborrhoic
-anti-inflammatory
-anti-microbial
-well tolerated and safe
-natural origin
WHAT IS ICHTHYOL:
Ichthyol has anti-inflammatory, antibacterial and antiseptic properties.
The paste is effective for skin inflammation, acne, bruises and cracks.
The new formula of Ichthyol paste in the form of an emulsion, thanks to the presence of film-forming components, allows you to fix the active substance on the skin surface, provides additional protection of the epidermis from external factors.
The convenient packaging form allows economical and hygienic use of the product.
Ichthyol manufactures a pale sulfonated shale oil under the name of ICHTHYOL® PALE for application in cosmetic skin and hair care.
Scaling scalp or skin disorders as well as skin blemishes are frequently triggered by interaction of different factors.
With its broad spectrum of efficacy Ichthyol offers the basis for a functionally combined therapy with one active ingredient.
Ichthyols efficacy is clinically substantiated in human medicine.
In cosmetics Ichthyol belongs to the few examples of well documented active ingredients of natural origin.
The pale sulfonated shale oil is manufactured by Ichthyol according to the guidelines of good manufacturing practice (GMP).
Ichthyol is distinguished by high purity, good tolerance, galenic advantages and versatile efficacy against impure and inflamed skin.
Ichthyol is applied for natural and safe skin care against dandruff and itching and, therefore, offers new perspectives.
CHARACTERISTIC FEATURES:
-Natural origin (from highly sulphuric oil shale)
-high purity
-high safety factor
-good tolerance
-broad spectrum of efficacy
-reduces desquamations
-relief from skin blemishes
-reduces irritations and itching
-reduces excessive sebaceous activity
INDICATION FOR USE:
Ichthyol is recommended for use in complex therapy of various skin damages (burns, erysipelas etc.), neuralgias, and pain in joints.
Ichthyol has anti-inflammatory, antiseptic and analgesic effects.
APPLICATION:
Apply a thin layer of Ichthyol balm to the damaged skin area 2-3 times a day, then cover with a clean gauze dressing.
Wash Your hands thoroughly after balm application.
Ichthyol has anti-inflammatory, local pain-relieving and antiseptic properties.
Ichthyol is used externally in case of skin damages, in case of neuralgias, arthritis etc.
Ichthyol is used externally for treatment of skin diseases, skin burns etc.
Ichthyol is indicated for the treatment of inflammations and small skin infections, furunculosis, abscesses and superficial skin ulcers.
Ichthyol is ueful in the treatment of sweat glands inflammations.
USES:
For local applications.
Do not apply near the eyes and on mucosa.
REACTIVITY:
Ichthyol is incompatible with acids, alkaloids, carbonates, hydroxides and mercuric chloride.
Ichthyol is also incompatible with iodides and salts of iron and lead.
SYNONYM:
Ammonium bituminosulfonate
Ammonium bituminosulphonate
Ammonium ichthosulfonate
Ammonium sulfoichthyolate
Ichthammol
Ichthammolum
Ichthyolum
CHEMBL2109035
