ICTASOL

Ictasol is widely used in personal care products due to its beneficial properties:
Ictasol is used in creams and lotions for its anti-inflammatory and antimicrobial effects.
Ictasol provides relief from symptoms associated with this common skin condition.

CAS Number: 12542-33-5​
EC Number:  215-671-7 
Molecular Formula: C6H10ClNO
Molecular Weight:  it is not a single, pure chemical substance but a blend of various molecules, it does not have a single, defined molecular weight

SYNONYMS:
Sodium bituminosulfonate​, Sodium shale oil sulfonate​, Ichthyolic acid, sodium salt, Ictasol, sodium bituminosulfonate​,

Ictasol is a sulfonated shale oil extract known for its anti-inflammatory and antimicrobial properties.
Ictasol is a sodium bituminosulfonate produced from the light distillate fraction of shale oil.
Ictasol, also known as Ichthyolic acid, sodium salt, is a compound derived from natural sources, specifically from a unique type of shale oil through a process of dry distillation.

Ictasol is characterized by its high purity and safety profile, making it suitable for use in personal care products.
Ictasol is particularly noted for its anti-seborrheic and antimicrobial properties, which help alleviate symptoms associated with seborrheic dermatitis and other skin conditions.

Ictasol, also known as sodium bituminosulfonate, is a sulfonated shale oil extract recognized for its anti-inflammatory and antimicrobial properties.
Ictasol applies an adequate amount of the shampoo on wet hair and massage the skin of the scalp until foam is formed.

Let the shampoo act for some time.
Then wash your hair and skin thoroughly.
To reach the optimum effect, the Ichthammol shampoo should be applied 2 – 3 times a week for the period of about 4 to 6 weeks.

Regular use of the Ictasol shampoo once in a week is then recommended.
Ictasol is a light sulfonated shale oil
Ictasol is Lumipeau’s holy grail star ingredient for very good reasons.

Originating from the magnificent French Jura Mountains, Ictasol is mined from a beautiful limestone with organic matter that can be tracked back to phytoplankton found in a dazzling lagoon in the Mesozoic era (the age of the dinosaurs).

USES and APPLICATIONS of ICTASOL:
Dating back to centuries ago, this ultimate acne-fighting ingredient backed by intensive research was a favoured ancient medicine trusted and used by doctors in hospitals and private practices.
Ictasol has been clinically proven to improve the overall appearance of acne-prone skin condition by 94%* and reduce the number of pimples by 80%**.

The active ingredient, Ictasol, is favoured for acne treatments due to its multifunctional efficacies.
Acne is often triggered by a combination of several interlinked factors, such as excess oil and bacteria on the skin, therefore an ingredient that delivers a broad spectrum of anti-acne properties will be best suited to tackle it.

Chronic skin diseases have been treated with shale oil for over 100 years.
Ictasol inhibits excessive cell division and keratinization, relieves itching, and has anti-inflammatory properties.
Ictasol's antimicrobial, anti-irritant, and wound-healing properties have proven effective in many areas of application.

Light sulfonated shale oil—or Ictasol, in other words—provides valuable services in the healing of eczema, the exfoliation of dandruff and dandruff, and in the external treatment of skin conditions such as skin ulcers and boils.
Other indications include nail bed inflammation, psoriasis, rosacea, itching due to senile senescence, acne, diaper rash, atopic dermatitis, and anal itching.

The combination of anti-inflammatory and antimicrobial properties ensures excellent results in the removal of skin blemishes such as pimples.
After a six-week treatment phase with more than 100 test subjects and a concentration of 1.0 percent Ictasol, the efficacy was rated either “very good” or “good” in more than 75 percent of cases.

The effectiveness of a formulation containing 1.0 percent Ictasol and 0.5 percent salicylic acid has also been tested in a study.
The average number of visible skin changes decreased by 80 percent during the eight-week treatment phase.
Ictasol is widely used in personal care products due to its beneficial properties:

Anti-Dandruff Treatments: Its effectiveness in reducing dandruff makes Ictasol a popular ingredient in shampoos.
Skin Care Products: Ictasol is used in creams and lotions for its anti-inflammatory and antimicrobial effects.
Seborrheic Dermatitis Treatments: Ictasol provides relief from symptoms associated with this common skin condition.

Preservative Agent: Ictasol acts as a natural preservative in cosmetic formulations by preventing microbial contamination.
Skincare: Ictasol is utilized in creams and lotions for its anti-inflammatory and antimicrobial effects, aiding in reducing redness and combating acne.

Haircare: Ictasol is employed in anti-dandruff shampoos due to its effectiveness in reducing dandruff and improving overall scalp health.
Ictasol is utilized in various formulations due to its effectiveness in reducing skin impurities, dandruff, and excess sebum production while maintaining good tolerability for users.
Ictasol is commonly used in skincare to help reduce redness, combat acne, and improve overall skin health.

-Antidandruff Shampoo uses of Ictasol:
Owing to its beneficial effect the shampoo with white Ictasol is recommended for care of the scalp in case of excess sebum production, itching and increased formation of dandruff.
Ictasol is also effective as a supportive agent in psoriasis of the scalp.

HOW IS ICTASOL OBTAINED?
Ictasol is extracted from natural shale, or rather from highly sulfur-containing oil shale.
Ictasol originates from deposits of tiny algae in a specific lagoon environment in the Alpine region during the Mesozoic (Central Earth) era.

During the biological decomposition of phytoplankton, sulfate-reducing bacteria were able to form organically bound sulfur in the biomass.
Over time, sedimentary rocks known as oil shale formed from these deposits, which contain the now solid marine biomass.

Extraction requires dry distillation of the oil shale at 450 degrees Celsius.
Various fractions are collected and separated by condensation.

Ictasol naturally has a rather strong, distinctive odor, which can, however, be optimized for cosmetic applications.
The shorter, earlier-boiling molecules, however, are lighter and less odorous than the darker, viscous, higher-boiling fraction.

The ingredients of the dark ammonium bitumen sulfonate increase blood flow and soften the skin.
We know this effect from the corresponding drawing ointments, which accelerate the permeation of pus to the outside in purulent skin processes.

This reduces pressure pain and, in a sense, draws the inflammation outward.
The light-colored bitumen sulfonate has only a reduced pulling effect and is therefore used for superficial skin diseases.

In principle, sulfonated shale oils do not exhibit any carcinogenic, teratogenic or mutagenic properties, they are well tolerated, and no photosensitizing or phototoxic effects have been observed to date.

FUNCTIONS OF ICTASOL IN COSMETIC PRODUCTS:
*ANTI-SEBORRHEIC
Ictasol prevents or relieves the symptoms of seborrhea and/or seborrheic dermatitis; and/or acts against dandruff

*ANTIMICROBIAL
Ictasol inhibits the growth of microorganisms (e.g. bacteria and fungi)

PAHs IN ICTASOL?
Ictasol is rich in sulfur, extremely pure in terms of PAHs (less than 0.001 ppm benzo[a]pyrene), and water-soluble.
Due to its similar spectrum of activity and its typical odor, Ictasol is often still classified as a tar.

However, this is incorrect, as Ictasol is actually a gentle alternative to coal tar.
Due to the toxicity of the tar, cosmetic coal tar shampoos have been banned from production within the EU since 1996.

Coal tar is heavily contaminated with PAHs (more than 5000 ppm benzo[a]pyrene), low in sulfur, and insoluble in water.
Furthermore, there is clear evidence of mutagenicity and carcinogenicity.

The good tolerability of Ictasol, however, has already been demonstrated in numerous toxicological studies.
The active ingredient, Ictasol, is suitable for both short-term and long-term administration.
Ictasol can be used for rinse-off products (e.g. shampoos) and leave-on products (e.g. body lotions).

KEY BENEFITS OF ICTASOL:
*Ictasol reduces redness and inflammation
*Ictasol combats acne with antimicrobial properties
*Ictasol improves skin texture

FUNCTION OF ICTASOL:
*Antibacterial/Antimicrobial ingredients - regulate the formation of bacteria and prevent their proliferation
*This raw material, Ictasol, is sodium bituminosulfonate obtained from the light distillation fraction of shale oil.
*Ictasol is obtained by sulfonating the destructive distillation product of certain bituminous schists and neutralizing it with sodium hydroxide.

EXTRACTION OF ICTASOL:
by dry distillation at approximately 450 degrees Celsius from oil shale from phytoplankton

INCI FUNCTION OF ICTASOL:
*Antiseborrhoeic, 
*antimicrobial

USES AND BENEFITS OF ICTASOL:
*Skincare: 
Ictasol is utilized in creams and lotions for its anti-inflammatory and antimicrobial effects, aiding in reducing redness and combating acne.

*Haircare: 
Ictasol is employed in anti-dandruff shampoos due to its effectiveness in reducing dandruff and improving overall scalp health.

*Dermatology: 
Ictasol is used in the treatment of various skin conditions, including rosacea, by modulating inflammatory mediators.

CHARACTERISTICS OF ICTASOL:
*Anti-inflammatory Properties: 
Ictasol reduces the generation of inflammatory mediators from human neutrophils, which may account for its effectiveness in treating conditions like rosacea.

*Antimicrobial Activity: 
Effective against certain bacteria and fungi, making it beneficial in treating skin infections and conditions associated with microbial activity.

*Sulfur Content: 
Ictasol contains organically bound sulfur, contributing to its therapeutic properties.

PRODUCTION OF ICTASOL:
Ictasol is derived from the light distillate fraction of shale oil. 
The production involves dry distillation of sulfur-rich oil shale, followed by sulfonation and neutralization with sodium hydroxide to produce the sodium salt.

CHEMICAL REACTIONS OF ICTASOL:
The synthesis of Ictasol involves the sulfonation of low-boiling oil fractions from shale oil using concentrated sulfuric acid.
This reaction yields a sulfonate salt, which possesses surfactant properties due to its amphiphilic nature—comprising both hydrophilic and lipophilic components.

The general reaction can be represented as follows:
R SO3That + H2SO4 → R SO3H + NaHSO4

Here, R represents the organic fraction derived from the shale oil.
The resulting compound exhibits stability across a wide pH range, although strong acids may cause precipitation.

BIOLOGICAL ACTIVITY OF ICTASOL:
Ictasol demonstrates significant biological activity, primarily through its anti-seborrheic and antimicrobial effects.
It effectively reduces symptoms associated with seborrheic dermatitis, such as redness, itching, and flaking.
Additionally, Ictasol inhibits bacterial growth on the skin, which helps prevent infections and maintains skin health.
Ictasol's antimicrobial properties extend to preventing the spoilage of cosmetic products by inhibiting microbial growth.

SYNTHESIZING OF ICTASOL:
The primary method for synthesizing Ictasol involves the following steps:

*Extraction: 
Shale oil is extracted from specific rock formations.

*Dry Distillation: 
The extracted shale oil undergoes dry distillation to concentrate the sulfur-rich components.

*Sulfonation Reaction: 
The concentrated oil fraction is treated with concentrated sulfuric acid to produce the sulfonate salt (Ictasol).

*Purification: 
The product is purified to achieve high purity levels suitable for cosmetic applications.
This method ensures that Ictasol retains its beneficial properties while adhering to good manufacturing practices.

*Effect: 
Ictasol helps against dandruff on the scalp, inhibits the growth of microorganisms such as fungi and bacteria, anti-inflammatory

PHYSICAL and CHEMICAL PROPERTIES of ICTASOL:
CAS Number: 12542-33-5​
EC Number: Not specified in the provided sources​
Molecular Formula: Not specified in the provided sources​
Molecular Weight: Not specified in the provided sources​
Appearance: Pale liquid​
Solubility: Water-soluble​
Odor: Characteristic bitumen-like odor​
INCI: Ictasol
Alternative names: Ichthyolic acid, sodium salt
CAS number: 1340-06-3, 12542-33-5
EINECS/ELINCS number: 215-671-7

FIRST AID MEASURES of ICTASOL:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of ICTASOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up dry. 
Dispose of properly. 
Clean up affected area.

FIRE FIGHTING MEASURES of ICTASOL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of ICTASOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection. 
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A 
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of ICTASOL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.

STABILITY and REACTIVITY of ICTASOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available