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IMIDAZOLIDIN-2-ONE

Imidazolidin-2-one is found in particular in the chemical structure of vitamin B8.
Imidazolidin-2-one is a dopamine receptor agonist.
Imidazolidin-2-one is used as a reagent in the synthesis of some drugs.

CAS Number: 120-93-4
Molecular Formula: C3H6N2O
Molecular Weight: 86.09
EINECS Number: 204-436-4

Synonyms: 2-Imidazolidone, imidazolidin-2-one, 120-93-4, 2-Imidazolidinone, ETHYLENEUREA, imidazolidinone, Ethylene urea, N,N'-Ethyleneurea, 2-Oxoimidazolidine, 1,3-Ethyleneurea, Imidazolid-2-one, Monoethyleneurea, 2-Oxomidazolidine, Urea, 1,3-ethylene-, SD 6073, 2-imidazolidinon, Urea, N,N'-(1,2-ethanediyl)-, NSC 21314, MFCD00005257, DTXSID0020602, CHEBI:37001, Urea,3-ethylene-, NSC-21314, WLN: T5MVMTJ, 2K48456N55, Urea,N'-(1,2-ethanediyl)-, HSDB 4021, EINECS 204-436-4, imidazolidone, 2-imidazolinone, AI3-22151, 2-Imidazolidone (Ethylene urea), imidazolin-2-one, mancozeb TP2, UNII-2K48456N55, Imidazoliden-2-one, 2-oxo-imidazolidine, 2-Imidazolidone, 96%, EC 204-436-4, ETHYLENEUREA [HSDB], CHEMBL12034, DTXCID20602, 2-IMIDAZOLIDINONE [MI], NSC3338, NSC-3338, NSC21314, Tox21_200783, AKOS000121325, NCGC00248832-01, NCGC00258337-01, AS-13128, BP-21148, CAS-120-93-4, PD065555, DB-021217, DB-021218, CS-0075560, I0005, NS00008037, EN300-21266, D71145, 2-Imidazolidinon 100 microg/mL in Acetonitrile, 2-Imidazolidone, PESTANAL(R), analytical standard, Q-200290, Q2813813, F0001-0335, Z104494954, InChI=1/C3H6N2O/c6-3-4-1-2-5-3/h1-2H2,(H2,4,5,6, 65118-65-2., 1,3-ethylene-ure;1,3-Ethyleneurea;2-Oxoimidazolidine;2-oxomidazolidine;Ethylenurea;Imidazolid-2-one;Imidazoliden-2-one;Imidazolidin-2-on

Imidazolidin-2-one has been shown to have affinity for 5-HT1A and 5-HT2C receptors
Imidazolidin-2-one has been used in vivo studies to assess its effect on serotonin levels.
Imidazolidin-2-one also binds with high affinity to adrenergic receptors, including the D3 receptor.

Imidazolidin-2-one may be useful as a ligand for studying dopamine D3 receptors.
Imidazolidin-2-one is a metabolite of ethylenethiourea (ETU), a decomposition product of the ethylenebis(dithiocarbamate) (EBDC) fungicides.
Imidazolidin-2-one is an organic compound that is used in the synthesis of glycol ethers.

Imidazolidin-2-one has also been shown to inhibit the production of proinflammatory cytokines and reduce light emission.
Imidazolidin-2-one is a structural analog of imidazolidinones, which are known to possess antiinflammatory activity.
Imidazolidin-2-one is a dopamine receptor agonist.

Imidazolidin-2-one is used as a reagent in the synthesis of some drugs.
Imidazolidin-2-one is a metabolite of ethylenethiourea (ETU).

Imidazolidin-2-one is a decomposition product of the ethylenebis(dithiocarbamate) (EBDC) fungicides.
Imidazolidin-2-one is a polar solvent and Lewis base.
Imidazolidin-2-one is mainly used as high-effect formaldehyde removing detergents

Imidazolidin-2-one is a white crystalline powder, which can be dissolved in water.
Imidazolidin-2-one can be used as anti-crease agent, de-aldehyde agent and crosslinking agent.
Imidazolidin-2-one’s also the main composition of air freshener.

Imidazolidin-2-one is an important additives of ink for inkjets.
Imidazolidin-2-one can also imporve the color contrast to enhance the printing effect.
Imidazolidin-2-one can be used as home air formaldehyde potent enzyme.

Imidazolidin-2-one can be used as intermediates for anti-schistosomiasis drugs.
Imidazolidin-2-one can be used as basic raw materials of third-generation penicillin.
Chiral microporous materials from achiral precursors Aryl and heteroaryl N-acylureas via microwave-assisted palladium-catalyzed carbonylation.

A highly water-soluble peptide based human neutrophil elastase inhibitor, Heterocycles by cyanoacetylation for antimicrobial use.
Imidazolidin-2-one is a white to light yellow crystalline solid.
It is soluble in water and organic solvents like alcohol and acetone.

Imidazolidin-2-one is used as a building block in the synthesis of various chemicals, particularly in the pharmaceutical industry.
It is involved in the synthesis of bioactive compounds and can be modified to produce more complex derivatives used for medicinal purposes.
Imidazolidin-2-one can be used in the production of fungicides, herbicides, and other agrochemicals, where the imidazolidine ring structure plays a role in their bioactivity.

It can be used as a monomer or intermediate in the synthesis of polymers, particularly those with nitrogen-containing backbones, which may have specialized properties like enhanced stability or reactivity.
Derivatives of Imidazolidin-2-one have been explored for their potential in treating various medical conditions due to their ability to form stable complexes with metals or interact with biological systems.
Imidazolidin-2-one is a member of ureas and an imidazolidinone.

Imidazolidin-2-one is a heterocyclic chemical compound .
Imidazolidin-2-one is composed of an imidazolidine core ( fully saturated imidazole) with a ketone function on the carbon between the two nitrogen atoms.
Imidazolidin-2-one is used as a herbicide and insecticide.

Imidazolidin-2-one is found in particular in the chemical structure of vitamin B8.
Imidazolidin-2-one is a dopamine receptor agonist.
Imidazolidin-2-one is used as a reagent in the synthesis of some drugs.

This compound has been shown to have affinity for 5-HT1A and 5-HT2C receptors
Imidazolidin-2-one has been used in vivo studies to assess its effect on serotonin levels.
Imidazolidin-2-one also binds with high affinity to adrenergic receptors, including the D3 receptor.

Imidazolidin-2-one may be useful as a ligand for studying dopamine D3 receptors.
Imidazolidin-2-one is a formaldehyde scavenger, which reduces at different extent the formaldehyde content in various industrie textile and construction.
Imidazolidin-2-one is a member of ureas and an imidazolidinone.

Cotton products comprise long-chain cellulose containing many hydroxyls to form spacious hydrogen bonds. These hydrogen bonds will be broken and randomly reformed under heat or external forces. That’s how the fabric folds come.
Imidazolidin-2-one exhibits moderate polarity and solubility in water, which contributes to its utility in different industrial and l settings.
In practical applications, Imidazolidin-2-one is employed as a building block in the synthesis of pharmaceuticals and agrochem.

Imidazolidin-2-one's role as an intermediate is significant in the development of various biologically active compounds, includin with therapeutic properties.
Due to its carcinogenic character, the presence of formaldehyde in leather continues to be a subject of great concern.
By using formaldehyde scavengers like Imidazolidin-2-one, it is possible to reduce the formaldehyde content in the final product 2-imidazolidone is effective formaldehyde scavenger in amino-resins like urea-formaldehyde (UF), melamine-formaldehyde (Murea-formaldehyde (MUF) condensates.

Imidazolidin-2-one is an organic compound with the molecular formula C₃H₆N₂O, characterized by its five-membered heterocyc two nitrogen atoms and one carbonyl group.
The structure of Imidazolidin-2-one consists of a ring with nitrogen atoms at positions 1 and 3, and a carbonyl group (C=O) atta second carbon atom of the ring.
This configuration imparts a range of chemical and physical properties to Imidazolidin-2-one, making it versatile in various app Chemically, 2-Imidazolidinone is notable for its stability and reactivity, particularly in forming complexes with metals and othe molecules.

Imidazolidin-2-one can act as a nucleophile due to the lone pair of electrons on the nitrogen atoms, making it useful in various reactions and syntheses.
Additionally, Imidazolidin-2-one serves as a stabilizing agent in certain chemical processes and formulations.
Imidazolidin-2-one is also used in research to investigate the properties and reactions of imidazolidinone derivatives.

Imidazolidin-2-one's ability to form stable complexes and participate in a range of chemical transformations makes it a valuabl synthetic chemistry and material science.
Imidazolidin-2-one is an organic compound with the molecular formula C₃H₆N₂O, characterized by its five-membered heterocyc two nitrogen atoms and a carbonyl group, which imparts a range of chemical and physical properties.
Imidazolidin-2-one is used as a building block in the synthesis of pharmaceuticals and agrochemicals, serving as an intermedia development of biologically active compounds and stabilizing agents.

Imidazolidin-2-one has been shown to have affinity for serotonin and adrenergic receptors, and it is a metabolite of ethyleneth decomposition product of EBDC fungicides.
The chemical structure of Imidazolidin-2-one is characterized by a 5-membered ring containing two nitrogen atoms at positions 1 and 3, and a carbonyl group (C=O) attached to position 2.

2-Imidazolidone (Ethylene Urea) reacts with hydroxyl groups when treating fabrics with formaldehyde, forming a stable structure to prevent the folds from forming. This method can also restain the pungent odor caused by using formaldehyde only as the anti-wrinkle treatment by effectively inhibiting the release of formaldehyde.
Besides, urea resin is another widely used textile finishing agent. 
Its residues on fabrics slowly release formaldehyde, which can be effectively inhibited by 2-Imidazolidone (Ethylene Urea).

Imidazolidin-2-one is a member of ureas and an imidazolidinone.
Imidazolidin-2-one is a heterocyclic chemical compound.
Imidazolidin-2-one is composed of an imidazolidine core ( fully saturated imidazole) with a ketone function on the carbon between the two nitrogen atoms.

Imidazolidin-2-one is used as a herbicide and insecticide.
Imidazolidin-2-one, is a heterocyclic organic compound featuring both an imidazolidine ring and a carbonyl group (C=O) attached at position 2 of the ring. 
Imidazolidin-2-one is a member of the imidazolidine family of compounds, which contain a five-membered ring with two nitrogen atoms.

Imidazolidin-2-one's unique structural features and reactivity profile enable it to play a crucial role in various chemical and industrial processes.
Imidazolidin-2-one can be synthesized by reacting trifluoroacetic acid with an aromatic hydroxyl group and two nitrogen atoms.
The major metabolic pathways for Imidazolidin-2-one include oxidation, reduction, hydrolysis, and conjugation with glucuronic acid.

Imidazolidin-2-one reacts with water molecules to form hydrogen peroxide and molecular oxygen gas.
Imidazolidin-2-one is a metabolite of ethylenethiourea (ETU), a decomposition product of the ethylenebis(dithiocarbamate) (EBDC) fungicides.
Imidazolidin-2-one is a largely obsolete insecticide.

Imidazolidin-2-one is a metabolite of ethylenethiourea (ETU), a decomposition product of the ethylenebis(dithiocarbamate) (EBDC) fungicides.
Imidazolidin-2-one is a member of ureas and an imidazolidinone.
Imidazolidin-2-one is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.

Imidazolidin-2-one is white to off-white solid.
Imidazolidin-2-one is a heterocyclic chemical compound.

Imidazolidin-2-one is used as a herbicide and insecticide.
Imidazolidin-2-one is found in particular in the chemical structure of vitamin B8.

Boiling point: 138-140/0.11mm
Density: 1.137±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: viscous oil
pka: 14.42±0.20(Predicted)
color: Orange

Imidazolidin-2-one is the reagent used in permanent press clothing.
Imidazolidin-2-one serves mainly as a formaldehyde scavenger and chemical building block.
Apart from the textile industry Imidazolidin-2-one is used in construction and coatings industry applications.

Imidazolidin-2-one is mainly used in various kinds of formaldehyde removing formulations such as high-effect formaldehyde removing detergents and long-term formaldehyde dissolution intermediates.
Imidazolidin-2-one can be used as intermediates of many new antibiotics, such as meloxicillin and aloxicillin, as intermediates for antischistosomiasis drugs, and as basic raw materials of third-generation penicillin.
In the biological field, Imidazolidin-2-one can be used to produce the plant growth regulators, fungicides, inhibitors, herbicides, etc., such as: Nchlorocarbonyl-2-imidazolidinone, 1-chlorocarbonyl-3-acetyl-2-imidazolidinone, 1-chlorocarbonyl-3-methanesulfonyl-2-imidazolidinone Nchloroformyl-2-imidazolidinone, 1-chloroformyl-3 acetyl-2-imidazolidinone, 1-chloroformyl-3-methanesulfonyl-2-imidazolidinone, Nhydroxyethyl-2-imidazolidinone, 1-methanesulfonyl-2-imidazolidinone, 1,3-dimethyl-2-imidazolidinone, 1-acetyl-2-imidazolidinone, etc.

Imidazolidin-2-one is used as Aryl and heteroaryl N-acylureas via microwave-assisted palladium-catalyzed carbonylation.
Imidazolidin-2-one is used as a highly water-soluble peptide based human neutrophil elastase inhibitor.
Imidazolidin-2-one is used as Chiral microporous materials from achiral precursors.

Imidazolidin-2-one is used as formaldehyde capture agent, fine chemicals intermediates, also used in the preparation of resin and the preparation of plasticizers, paint, adhesives, etc.
Imidazolidin-2-one is used as formaldehyde capture agent to remove formaldehyde remaining in fabrics after finishing with 2D-resin, KB resin, urea-formaldehyde resin, melamine formaldehyde resin, etc.
Imidazolidin-2-one is also used as an intermediate for fine chemicals, used to make resins, plasticizers, paints, adhesives, etc.

Imidazolidin-2-one is used as a formaldehyde capture agent, an intermediate for fine chemicals, and also used to make resins and formulate plasticizers, spray paints, adhesives, etc.
Imidazolidin-2-one is used to synthesize chiral microporous materials prepared from achiral precursors.
Imidazolidin-2-one is used to prepare aryl and heteroaryl N-acylurea through microwave-assisted palladium-catalyzed carbonylation reaction.

Imidazolidin-2-one is used to synthesize a highly water-soluble peptide based on human neutrophil elastase inhibitors.
Imidazolidin-2-one formed by cyanoacetylation reaction used to synthesize antibacterial heterocyclic rings.
Imidazolidin-2-one is used for Pd-catalyzed reaction to form C- N bonds with heteroaromatic toluene sulfonate; used to activate the oxidative amidation reaction of alkenes.

Imidazolidin-2-one is mainly used in various kinds of formaldehyde removing reagent eg. 
For resinous product, Imidazolidin-2-one is used high effect formaldehyde removing detergent, long-term formaldehyde dissolution intermediate, formaldehyde removing for , leather, rubber, textile coating, and photocatolyst etc, In addition, 2-Imidazolidinone can be used in textile anti – crease finish, anti tearing finish.
Imidazolidin-2-one is used as a raw material.

Imidazolidin-2-one is a metabolite of ethylenethiourea (ETU).
Imidazolidin-2-one is a decomposition product of the ethylenebis(dithiocarbamate) (EBDC) fungicides.
Imidazolidin-2-one is thiadiazole pharmaceutical intermediate.

Imidazolidin-2-one can be used as reactant for synthesis of Chiral microporous materials from achiral precursors.
Imidazolidin-2-one is a class of 5-membered ring heterocycles structurally related to imidazole.
Imidazolidin-2-one feature a saturated C3N2 backbones, except for the presence of a urea or amide functional group in the 2 or 4 positions.

Imidazolidin-2-one is a polar solvent and Lewis base.
Drugs featuring this ring system include emicerfont, imidapril, and azlocillin.

Uses Of Imidazolidin-2-one: 
2-Oxoimidazolidine are used in the oil and gas industry, particularly in corrosion inhibitors for pipelines and equipment. 
Imidazolidin-2-ones help protect metal surfaces from the corrosive effects of oil, gas, and water in industrial environments.
Imidazolidin-2-one can be used as a crosslinking agent in polymer synthesis, where it helps link polymer chains together, enhancing the material's durability, strength, and resistance to environmental factors. 

This is particularly useful in producing coatings, adhesives, and composite materials.
Some imidazolidine derivatives, including those based on Imidazolidin-2-one, are being studied for their potential immunomodulatory effects. 
They could influence immune system responses, offering new avenues for developing immune-boosting or immune-suppressing therapies, particularly in the context of autoimmune diseases or immunotherapy.

The Imidazolidin-2-one scaffold is often used in the synthesis of other heterocyclic compounds, which can then be further modified for use in pharmaceutical development. 
The imidazolidine ring system can be a building block for molecules targeting a wide range of disease pathways, including cancer, bacterial infections, and neurodegenerative conditions.
Imidazolidin-2-one and its derivatives may be used in the development of chemical sensors, particularly for detecting gases or environmental pollutants. 

The ability to form stable interactions with certain ions or molecules makes it useful in creating sensitive detection devices.
In supramolecular chemistry, Imidazolidin-2-one derivatives are studied for their ability to form non-covalent interactions with other molecules, particularly metal ions. 
These interactions can be harnessed for creating molecular recognition systems, useful in applications ranging from chemical separations to targeted drug delivery.

Imidazolidin-2-one derivatives serve as catalysts in organic reactions, particularly in the formation of carbon-carbon or carbon-heteroatom bonds. 
These catalysts are often employed in sustainable chemistry, where they facilitate reactions under milder conditions, reducing the need for harsh reagents or extreme temperatures.
In addition to being used in agrochemical formulations, derivatives of Imidazolidin-2-one can also be incorporated into pesticides and veterinary drugs. 

Some compounds derived from 2-Oxoimidazolidine show activity against certain pests or have been tested for their potential to treat infections in livestock and pets.
2-Imidazolidinone is a metabolite of ethylenethiourea (ETU), a decomposition product of the ethylenebis(dithiocarbamate) (EBDC) fungicides.
Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

Imidazolidin-2-one can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).
Imidazolidin-2-one is used in the following products: inks and toners. 
Imidazolidin-2-one is used in the following areas: printing and recorded media reproduction. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Imidazolidin-2-one is a useful research chemical compound used in the preparation of alkyl and aryl azides by chemoselective diazotization of primary amines with in situ-generated fluorosulfonyl azide and their use in the preparation of a combinatorial library of 1,2,3-triazole.
Imidazolidin-2-one is often used as a building block in the synthesis of various organic compounds. 

The imidazolidine ring system is reactive, allowing it to participate in the formation of more complex molecules.
Imidazolidin-2-one and its derivatives are used in the pharmaceutical industry as intermediates in the synthesis of biologically active compounds. 

Imidazolidin-2-ones have potential therapeutic applications, particularly in the development of treatments for diseases where nitrogen-containing molecules are beneficial.
Certain derivatives of Imidazolidin-2-one exhibit antibacterial, antifungal, and anti-inflammatory properties, making them of interest for drug development.
Imidazolidin-2-one is used in the following products: inks and toners.

Release to the environment of Imidazolidin-2-one can occur from industrial use: formulation of mixtures and formulation in materials.
Imidazolidin-2-one is used in the following products: adsorbents and inks and toners.
Imidazolidin-2-one is used in the following areas: printing and recorded media reproduction.

Release to the environment of Imidazolidin-2-one can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.
Imidazolidin-2-one can be used as reactant for synthesis of Chiral microporous materials from achiral precursors.

Imidazolidin-2-one is used in the production of agrochemicals, including fungicides and herbicides. 
The imidazolidine ring structure helps these compounds interact with biological systems, enhancing their effectiveness in controlling plant diseases or pests.
This compound can be used as an intermediate for the production of polymers that feature nitrogen-containing backbones. 

These polymers may have specific properties like enhanced chemical resistance, stability, or reactivity. 
Such polymers could be used in applications ranging from coatings to specialty plastics.
Derivatives of Imidazolidin-2-one are sometimes used as corrosion inhibitors in materials science. 

The ability to form stable complexes with metals is useful for protecting metal surfaces.
Imidazolidin-2-one can be involved in catalytic reactions, especially those that require the formation of stable complexes with metal ions or other reactive species. 
This can be beneficial in synthetic chemistry, where specific reaction pathways need to be controlled.

Imidazolidin-2-one is also used in research to explore new chemical reactions and to develop novel compounds with specific functions. 
Its versatility as a synthetic intermediate makes it a useful tool in chemical and pharmaceutical research labs.
Imidazolidin-2-one has been explored in chemo-enzymatic processes, where enzymes are used to catalyze reactions involving this compound. 

Such reactions can offer high specificity, milder conditions, and potentially greener alternatives to traditional chemical methods in the synthesis of pharmaceutical or agrochemical intermediates.
Some derivatives of Imidazolidin-2-one are used as stabilizing agents in pharmaceutical formulations. 
Their chemical structure can help stabilize sensitive active ingredients in medications, improving shelf life and bioavailability.

Imidazolidin-2-one is involved in the synthesis of peptoids—a class of compounds similar to peptides but with modified backbones. 
Peptoids have found applications in drug design, particularly in creating molecules that mimic protein interactions or possess unique biological activities.

Safety Profile Of Imidazolidin-2-one:
Imidazolidin-2-one is not highly flammable but may burn if exposed to a high enough ignition source.
Fine powders of Imidazolidin-2-one, when dispersed in air, can form an explosive mixture, especially in confined spaces.
It is not highly toxic to aquatic life but should still be prevented from entering water systems to avoid contamination.

Prolonged or repeated inhalation of dust may irritate the respiratory tract.
Imidazolidin-2-one prolonged exposure can cause mild skin irritation in sensitive individuals.

Can cause eye irritation if particles come into contact with the eyes.
Not classified as highly toxic, but ingestion of large amounts may cause gastrointestinal distress.

 

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