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IODOPROPYNYL BUTYLCARBAMATE

IODOPROPYNYL BUTYLCARBAMATE

CAS: 55406-53-6
European Community (EC) Number: 259-627-5

Molecular Formula: C8H12INO2
Molecular Weight:    281.09

IUPAC Name: 3-iodoprop-2-ynyl N-butylcarbamate

Color/Form: Off-white, dull color powder
Odor: Sharp pungent odor
Melting Point: 66 °C
Solubility: In water, 156 mg/L at 20 °C
Density: 1.575 g/mL
Vapor Pressure: 0.0000525 [mmHg]

Iodopropynyl butylcarbamate (IPBC) is a water-soluble preservative used globally in the paints & coatings, wood preservatives, personal care, and cosmetics industries. 
Iodopropynyl butylcarbamate is a member of the carbamate family of biocides.
Iodopropynyl butylcarbamate was invented in the 1970s and has a long history of effective use as an antifungal technology.

Iodopropynyl butylcarbamate is an effective bactericidal preservative, mainly used in cosmetics, household chemicals, paint, leather, plastic, wood, metal cutting fluid, wood color control, textiles, paper industry, ink, adhesives, etc.

Iodopropynyl butylcarbamate is non-irritating at a concentration of ≤ 0.1% and is a new anti-dandruff anti-itching agent.


Iodopropynyl butylcarbamate is used as a preservative in cosmetic formulations; it is acutely toxic by inhalation and should not be used in products that can be aerosolized or inhaled.


Iodopropynyl butylcarbamate was initially developed for use in the paint & coatings industry as a dry-film preservative to protect interior and exterior coatings from mold, mildew, and fungal growth, while also offering cost performance and sustainability benefits. 
Iodopropynyl butylcarbamate exhibits efficacy against a broad spectrum of fungal species, typically at very low use levels. 
Iodopropynyl butylcarbamate today is incorporated into a wide variety of interior and exterior paint formulations around the world.

Iodopropynyl butylcarbamate is a preservative used in cosmetics, wet wipes (toilet paper), and other personal care products. 
Iodopropynyl butylcarbamate is also used as a biocide in paints, primers, and industrial coolants and cooling lubricants.

Iodopropynyl butylcarbamate is a preservative that helps prevent mold, bacteria, and other germs from spreading in creams, lotions, and other products. 
Iodopropynyl butylcarbamate was used for years in paints, primers, and coolants, and only more recently in cosmetic products, as it is effective against a wide variety of microorganisms. 


Iodopropynyl butylcarbamate (IPBC) is an internationally recognized chemical that has been used for years because of its wide field of application. 
Initially used as a water-based paint and wood preservative and then in metalworking fluids, its role has expanded into the more recent uses in cosmetic products. 
The need for a potent, broad-spectrum, and safe preservative system in cosmetics allowed for the discovery of several combinations of IPBC effective against a wide variety of organisms. 


Iodopropynyl butylcarbamate is a carbamate ester that is carbamic acid in which the nitrogen has been substituted by a butyl group and in which the hydrogen of the carboxy group is replaced by a 1-iodoprop-2-yn-3-yl group. 
A fungicide, Iodopropynyl butylcarbamate is used as a preservative and sapstain control chemical in wood products and as a preservative in adhesives, paints, latex paper coating, plastic, water-based inks, metal working fluids, textiles, and numerous consumer products. 
Iodopropynyl butylcarbamate has a role as a xenobiotic, an environmental contaminant and an antifungal agrochemical. 
Iodopropynyl butylcarbamate is a carbamate ester, an organoiodine compound, an acetylenic compound and a carbamate fungicide.


Iodopropynyl butylcarbamate is a carbamate pesticide. 
Carbamate pesticides are derived from carbamic acid and kill insects in a similar fashion as organophosphate insecticides. 
They are widely used in homes, gardens and agriculture. 
The first carbamate, carbaryl, was introduced in 1956 and more of it has been used throughout the world than all other carbamates combined. 
Because of carbaryl's relatively low mammalian oral and dermal toxicity and broad control spectrum, it has had wide use in lawn and garden settings. 
Most of the carbamates are extremely toxic to Hymenoptera, and precautions must be taken to avoid exposure to foraging bees or parasitic wasps. 
Some of the carbamates are translocated within plants, making them an effective systemic treatment. 


Iodopropynyl butylcarbamate, also known as IPBC, is a white or slightly off-white crystalline powder that contains iodine. 
Iodopropynyl butylcarbamate is used in a wide variety of cosmetics and personal-care products.
Iodopropynyl butylcarbamate prevents or retards bacterial growth, thereby protecting cosmetics and personal-care products from spoilage.

Iodopropynyl butylcarbamate is an internationally recognized preservative that has been used for years because of a wide field of application. 
The need for a broad-spectrum and safe preservative system for cosmetics has led to the development of several combinations of IPBC with other preservatives effective against a wide variety of organisms. 
Iodopropynyl butylcarbamate is also used as a preservative in household products, paints, cements and inks.

Iodopropynyl butylcarbamate is a compound used as a fungicide and bactericide for wood and paint preservation and now also permitted and used as a cosmetics preservative.


Iodopropynyl butylcarbamate is an effective fungicide at very low concentrations in cosmetic and other products, and has shown very low sensitivity in humans tested with this preservative. 
Iodopropynyl butylcarbamate was approved in 1996 for use up to 0.1% concentrations in topical products and cosmetics. 
However, this preservative is mostly found in cosmetics at about one-eighth that level. 
IPBC Toxicity and Safety Tests show it to be generally safe: When used properly in leave-on skin products, IPBC is extremely safe. 

Uses:
-Adhesives
-Cements
-Inks
-Cooling fluids
-Coolants
-Fungicide and bactericide for wood and paint preservation
-Paints and primers
-Wallpaper
-Metal working fluids
-Wood preservative
-Skin care products/Cosmetics:
--Anti-itch and rash creams
--Bath products
--Bronzers and self-tanners
--Hair colorants/“Permanents-relaxers”
--Lip balms
--Make-ups and make-up removers
--Moisturizers
--Powders/Sprays
--Shampoos/Conditioners
--Shaving products

Storage:
Store in a cool dry and ventilated warehouse away from sunlight and fire


SYNONYMS:

55406-53-6
3-iodoprop-2-yn-1-yl butylcarbamate
Iodopropynyl butylcarbamate
3-Iodo--propynyl butylcarbamate
Iodocarb
Ipbc
Woodlife
3-Iodo-2-propynyl N-butylcarbamate
1-Iodoprop-1-yn-3-yl N-n-butylcarbamate
3-iodoprop-2-ynyl N-butylcarbamate
Carbamic acid, butyl-, 3-iodo-2-propynyl ester
Troysan KK-108A
3-Iodo-2-propynyl-N-butylcarbamate
3-IODO-2-PROPYNYLBUTYLCARBAMATE
Troysan polyphase anti-mildew
Butyl-3-iodo-2-propynylcarbamate
3-iodoprop-2-yn-1-yl N-butylcarbamate
603P14DHEB
CHEBI:83279
3-iodoprop-2-ynyl butylcarbamate
DSSTox_CID_8038
DSSTox_RID_78646
DSSTox_GSID_28038
Caswell No. 501A
CAS-55406-53-6
HSDB 7314
3-Iodo-2-propynyl butyl carbamate
EINECS 259-627-5
3-iodo-2-propynyl-N-butyl carbamate
EPA Pesticide Chemical Code 107801
BRN 2248232
iodocarbe
UNII-603P14DHEB
3-iodo-2-propyn-1-yl N-butylcarbamate
Carbamic acid, butyl-3-iodo-2-propynyl ester
IPBC [MI]
iodo-2-propynylbutylcarbamate
SCHEMBL114369
Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester
CHEMBL1893913
DTXSID0028038
ZINC185035
3-Iodo-2-propynyl butylcarbamate #
3-iodoprop-2-yn-1-ylbutylcarbamate
Tox21_201864
Tox21_301117
MFCD00072438
AKOS015905567
CS-W010051
GS-3240
Iodocarb 100 microg/mL in Acetonitrile
NCGC00164376-01
NCGC00164376-02
NCGC00164376-03
NCGC00164376-04
NCGC00164376-05
NCGC00255017-01
NCGC00259413-01
IODOPROPYNYL BUTYLCARBAMATE [INCI]
3-Iodo-2-propynyl N-butylcarbamate, 97%
3-Iodo-2-propynyl N-Butylcarbamate-[d9]
IODOPROPYNYL BUTYLCARBAMATE [VANDF]
3-IODO-2-PROPYNYL BUTYL CARBBAMATE
FT-0615885
I0666
IODOPROPYNYL BUTYL CARBAMATE [MART.]
N-Butylcarbamic Acid 3-Iodo-2-propynyl Ester
06I536
3-IODO-2-PROPYNYLBUTYLCARBAMATE [HSDB]
A830629
Q2928998
W-105563
3-Iodo-2-propynyl N-butylcarbamate, analytical standard

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