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Isethionate is prepared by the reaction of ethylene oxide with sodium bisulfite solution.
Isethionate is a combination of a type of sulphonic acid called Isethionic Acid and a fatty acid or sodium salt ester which is derived from coconut oil.
Isethionate is known to be non-allergic, non-irritating and non-toxic, hence used in a wide range of beauty products and toiletries.
CAS Number: 107-36-8
Molecular Formula: C2H6O4S
Molecular Weight: 126.13
EINECS Number: 203-484-3
Synonyms: ISETHIONIC ACID, 2-Hydroxyethanesulfonic acid, 107-36-8, 2-Hydroxyethanesulphonic acid, 2-Hydroxyethane-1-sulfonic acid, Hydroxyethylsulfonic acid, Ethanesulfonic acid, 2-hydroxy-, Ethanolsulfonic acid, Isethionate, 2-Hydroxyethanesulfonate, Caswell No. 502, (2-Hydroxyethyl)sulfonic acid, Kyselina isethionova, USAF DO-14, Kyselina isethionova [Czech], 2-hydroxyethylsulfonic acid, EPA Pesticide Chemical Code 047701, BRN 1751214, Kyselina 2-hydroxyethansulfonova [Czech], AI3-19644, Potassium isethionate, NSC-60516, 97J3QN9884, 2-hydroxyethane-1-sulfonate, NSC1898, Sodium beta-hydroxyethanesulfonate, 2-Hydroxyethanesulfonic acid(80% in water), EINECS 203-484-3, NSC 60516, Ethanolsulfonate, Kyselina 2-hydroxyethansulfonova, UNII-97J3QN9884, 8X3, Hydroxyethylsulfonate, 2-Hydroxyethanesulphonate, (2-Hydroxyethyl)sulfonate, SCHEMBL827, WLN: WSQ2Q, 2-Hydroxyethanesulfonicacid, bmse000242, bmse000819, 2-oxidanylethanesulfonic acid, ISETHIONIC ACID [MI], 4-04-00-00084 (Beilstein Handbook Reference), beta-hydroxyethanesulfonic acid, CHEBI:1157, DTXSID1041427, SUMDYPCJJOFFON-UHFFFAOYSA-N, HY-Y0095, NSC60516, AC-538, MFCD00242599, AKOS006228878, CS-W019640, 21561-88-6, AS-44331, PD040603, FT-0627313, Isethionic acid pound 80% in water pound(c), C05123, EN300-243452, A801683, Q339734, W-108750, 2-HYDROXYETHANESULPHONIC ACID (80% IN WATER).
Isethionate is most commonly available in the form of its sodium salt (sodium isethionate).
Isethionate exists as a solid, soluble (in water), and an extremely strong acidic compound (based on its pKa).
Isethionate has been primarily detected in urine.
Within the cell, Isethionate is primarily located in the cytoplasm.
Isethionate is an alkanesulfonic acid in which the sulfo group is directly linked to a 2-hydroxyethyl group.
Isethionate has a role as a human metabolite. It is a conjugate acid of an isethionate.
Isethionate a colorless, syrupy, strongly acidic liquid that can form detergents with oleic acid.
Isethionates are esters of long-chain aliphatic carboxylic acids (C8 – C18) with isethionic acid (2-hydroxyethanesulfonic acid) or salts thereof, such as ammonium isethionate or sodium isethionate.
Isethionate, for example, is a water-soluble salt derived from isethionic acid and is often used in formulations for shampoos, body washes, and other cleansing products.
The isethionate group in these compounds provides a sulfate-free alternative for cleansing, which can be milder on the skin and hair compared to traditional sulfate-based surfactants.
Isethionates are known for their ability to produce a creamy lather and effective cleansing while being less harsh, making them suitable for individuals with sensitive skin.
Isethionate is discovery is generally attributed to Heinrich Gustav Magnus, who prepared it by the action of solid sulfur trioxide on ethanol in 1833.
Like the taurides, isethionates are a class of particularly mild anionic surfactants which, unlike ordinary soaps, retain their washing-active properties even in hard water.
Isethionates are obtained on an industrial scale reacting mixtures of carboxylic acids with salts of isethionic acid under acidic catalysis e. g. with methanesulfonic acid.
The mixtures of carboxylic acids are obtained from the hydrolysis of animal fats (tallow) or vegetable oils, preferably coconut oil, but also palm oil, soybean oil or castor oil.
Isethionate is known for its mild and gentle cleansing properties.
Isethionate is a chemical compound commonly used in the formulation of personal care and cosmetic products, especially in skincare, haircare, and bath products.
Isethionate is used as a cleansing agent in many skincare, haircare, cleaning products.
Isethionate effectively removes dirt, oils, and impurities from the skin and hair without causing excessive dryness or irritation, making it suitable for sensitive skin types.
Isethionate has the ability to create a rich and stable lather in products like shampoos, body washes, and facial cleansers, enhancing the overall user experience.
Isethionate is considered to be biodegradable, which means it can break down in the environment over time, making it a more environmentally friendly choice compared to some other surfactants.
Isethionate is derived from coconut oil, which is a natural source, and this can be an appealing feature for consumers looking for more natural or plant-based ingredients in their personal care products.
Isethionate is less likely to cause skin and eye irritation compared to harsher surfactants, which makes it a preferred choice for products intended for sensitive skin or for use on the face.
Isethionate is compatible with a wide range of cosmetic ingredients, making it suitable for use in various product formulations.
Isethionate can be used in various types of personal care products, including shampoos, body washes, facial cleansers, bar soaps, solid shampoo bars, baby care products, and more.
Isethionate is often used in solid formulations like shampoo bars and soap bars, contributing to their stability and effectiveness.
In addition to its cleansing abilities, Isethionate can also act as an emulsifier, helping to mix and stabilize oil and water-based ingredients in products.
Many manufacturers prioritize responsibly sourced ingredients, and Isethionate can be sourced sustainably, aligning with environmentally conscious practices.
Isethionates are solids which are often mixed with fatty acids (up to 30% by weight) to lower their freezing point.
Despite its low water solubility (100ppm at 25 °C), the lower-priced Isethionate has found more widespread use than its well water-soluble ammonium salt (> 25 wt.% at 25 °C).
To solubilize the sparsely soluble isethionates and taurides, the formation of mixtures with amphoteric surfactants (such as cocamidopropyl betaine) are proposed.
From such mixtures, Isethionate is possible to prepare liquid, clear and transparent aqueous concentrates which are liquid at room temperature.
Isethionates are characterized by excellent skin compatibility, excellent foaming (even in hard water), good cleansing properties and a pleasant skin feel.
They are non-toxic and readily biodegradable.[citation needed] However, in contrast to the taurides, they are not long-term stable outside a pH range of 5 to 8.
Isethionates are used in solid soaps (so-called syndet bars) and in other personal care products such as lotions, washing and shower gels, shampoos, liquid soaps, shaving creams, and other cosmetic and dermatological preparations.
Isethionate is a mild surfactant specifically designed for use in personal cleansing products.
Isethionate is nearly salt-free and resistant to hard and salt water with high foaming properties.
Isethionate is compatible with soap and gives excellent lime-soap dispersibility in order to retard the formation of scum in bar soaps.
Isethionate is a fine, white powder, soluble in soft or hard water at all pHs.
Isethionate is stable in formulations at near-neutral pH and room temperature for extended periods of time but will gradually hydrolyze at elevated temperatures.
Isethionate is naturally derived from coconut and is considered ‘readily biodegradable’ according to OECD Guidelines.
Isethionate is considered a mild surfactant and is often used in soap bars, shampoos, and bubble baths and provides a dense, creamy lather.
Isethionate Raw Material is a surfactant made up of Isethionic Acid, a form of sulphonic acid, and the fatty acid – or sodium salt ester – produced from Coconut Oil.
Isethionate’s commonly referred to as Baby Foam because of its outstanding mildness.
Isethionate has long been used as a substitute for sodium salts obtained from animals, such as sheep and cattle.
Isethionate is a new generation surfactant that is salt and sulfate free, has excellent detergency, and is used as a gentle cleansing agent in several applications in hair and skin care like shampoos, body washes, facial cleansers.
Isethionate is a high foaming product that when used will provide dense, creamy lather to formulations.
Isethionate is a mild surfactant (cleansing agent) derived from isethionic acid and coconut fatty acids.
In its raw state, Isethionate usually appears as white granular solids.
Isethionate's created by combining sodium isethionate with coconut oil fatty acids.
Isethionate has been a predominant ingredient in syndet bar formulation for more than thirty years.
Although cost effective and well recognized for good skin compatibility, Isethionate is not regularly found in liquid detergent systems due to its limited solubility in water.
The solubility of Isethionate in water is unfavorable in terms of enthalpy of solvation.
When setting up equilibrium of solubilization, there are three possible phases, and three methods have been developed to prevent Isethionate from recrystallizing in aqueous solutions.
The first focuses on tying Isethionate ions within micelles made of secondary surfactants.
Isethionates are organic compounds which aid the blending of liquids which do not ordinarily mix, most obviously oil and water.
The isethionate has both a hydrophilic (water-loving) and hydrophobic (water fearing) element and is therefore attracted to water and oil alike.
Isethionate Powder is biodegradable, non-toxic and vegan friendly.
Isethionate can be used in personal care products as a gentle surfactant, helping to mix water with oil and dirt so they can be washed away, without stripping the skin's natural barrier.
Like many coconut-derived cleansers, Isethionate also contributes to lather, producing a luxurious creamy foam that does not dry out skin.
Isethionate is ultra-mild properties make it ideal for delicate or sensitive skin, and it is often used as a plant-based alternative to animal-derived sodium salts.
They are also referred to as acyl isethionates or acyloxyethanesulfonates.
Isethionate refers to a type of chemical compound that contains the isethionate ion.
The isethionate ion is derived from isethionic acid, a sulfonic acid with the chemical formula CH3(CH2)2CH(NHSO3H)CO2H.
The corresponding isethionate ion is often written as CH3(CH2)2CH(NHSO3-)CO2-, where the negative charge is localized on the oxygen atom.
Isethionate compounds are commonly used in personal care and cosmetic products due to their mild and gentle cleansing properties.
Isethionate, also known as 2-Hydroxyethanesulfonate or 2-hydroxyethylsulfonic acid, belongs to the class of organic compounds known as organosulfonic acids.
Organosulfonic acids are compounds containing the sulfonic acid group, which has the general structure RS(=O)2OH (R is not a hydrogen atom).
Isethionate Powder is a particularly mild surfactant derived from coconut.
Isethionate, the ethyl chain sulfonic acid containing hydroxy group, is a water soluble, strongly acidic liquid; used in the manufacture of mild, biodegradable and high foaming anionic surfactants which provides gentle cleansing and soft skin feel.
Isethionate is a white water-soluble solid used in the manufacture of certain surfactants and in the industrial production of taurine.
Isethionate is an organosulfur compound containing an alkylsulfonic acid located beta to a hydroxy group.
Isethionate is the trivial name for 2-hydroxyethanesulfonic acid which is the parent compound of sodium isethionate.
Melting point: <25 °C
Boiling point;: 226℃ at 101.3kPa
Density: 1.344 (estimate)
vapor pressure: 0Pa at 25℃
refractive index: 1.5090 (estimate)
storage temp.: 2-8°C
solubility: Methanol (Slightly), Water (Soluble)
form: Colourless Solution
pka: 1.39±0.50(Predicted)
LogP: -1.65 at 25℃ and pH2
Dissociation constant: -1.68 at 20℃
CAS DataBase Reference: 107-36-8(CAS DataBase Reference)
EWG's Food Scores: 1
Isethionate's high foaming capacity maintains the moisture in skin.
Isethionate is a cleansing ingredient used in skincare and haircare formulations.
Isethionates are commonly used in the formulation of syndet bars, which are synthetic detergent bars that provide an alternative to traditional soap bars.
Syndet bars are known for being less harsh on the skin.
In facial cleansers and exfoliating products, isethionates contribute to a luxurious and creamy texture while ensuring effective cleansing without causing excessive dryness.
Isethionates are water-soluble, making them suitable for use in water-based cleansing products, where they can be easily incorporated into formulations.
Isethionates typically exhibit good pH stability, allowing them to maintain their effectiveness over a range of pH levels commonly found in personal care products.
Isethionate is derived from coconut oil.
Isethionate is primarily used in soaps, cleansers, shampoos, and cleansing products due to its surfactant abilities.
Isethionate is usually used in concentrations that range between 10-25%.
There are considered to be no issues with irritation, sensitivity, or toxicity at these concentrations.
Isethionate is a gentle surfactant derived from coconut oil that is commonly used in skincare and haircare products.
Isethionate is typically derived from coconut oil, hence the "cocoyl" part of its name.
Isethionate is a sodium salt produced from coconut oil.
Isethionate is a traditional substitute for sodium salts that are derived from animals, namely sheep and cattle.
Isethionate exhibits high foaming ability, producing a stable, rich and velvety lather that does not dehydrate the skin, making it ideal for addition to water-free products as well as skin care, hair care, and bath products.
Isethionate is an anionic compound and is also known as sodium isethionate.
Isethionate is also known as ‘Baby Foam’ because it is a surfactant which is exceptionally mild.
Isethionate is a fine white powder which has a mild odour.
One of the significant advantages of isethionates is that they provide sulfate-free cleansing. Sulfate-free formulations are often preferred by individuals with sensitive skin, as they are considered gentler.
Isethionate are commonly used in various hair care products, including shampoos and conditioners.
They help in cleaning the hair without stripping it of its natural oils.
In skincare products, such as facial cleansers and body washes, isethionates contribute to a gentle and effective cleansing experience.
Many isethionate surfactants are designed to be biodegradable, making them more environmentally friendly compared to some traditional surfactants.
Isethionates are often chosen for formulations in areas with hard water, as they tend to be more compatible and produce lather even in the presence of mineral ions.
This white, powdery substance has gained popularity due to its mild, non-irritating nature, making it suitable for a variety of personal care applications.
Isethionate is a sodium salt of the coconut fatty acid ester of isethionic acid.
Isethionate is an anionic surfactant, meaning it carries a negative charge that helps to create a lather and lift dirt, oil, and impurities from the skin and hair.
Isethionate, is a gentle surfactant which adds high foaming and cleansing properties to a cosmetic formula.
Isethionates are known for their mild surfactant properties.
They produce a rich, creamy lather that helps in the effective cleansing of skin and hair without causing excessive dryness or irritation.
The structure of isethionates, particularly the sulfosuccinate group, imparts unique characteristics to these surfactants, contributing to their mildness and versatility.
Cosmetic formulators appreciate isethionates for their flexibility in formulation, allowing the creation of products that meet the growing demand for milder and more skin-friendly cleansers.
Due to the increasing awareness of ingredient safety and consumer preferences for gentler formulations, isethionates have gained popularity in the personal care industry.
Due to their mild and gentle nature, isethionates are often included in baby care products, such as baby shampoos and washes, catering to the sensitive skin of infants.
In addition to personal care products, isethionates are sometimes used as detergent alternatives in household cleaning products, providing a milder option.
Formulations for cleansing wipes often include isethionates to provide effective cleaning in a convenient and portable format.
Isethionates can be compatible with conditioning agents, allowing formulators to create products that not only cleanse but also provide a conditioning effect on hair or skin.
Some isethionate formulations may include ingredients that contribute to hydration and moisturization, enhancing the overall skincare experience.
In response to consumer preferences for ethical and natural formulations, isethionates may be derived from natural sources or included in products that emphasize sustainability.
Isethionates contribute to the stability of formulations, helping to maintain the integrity of the product over time, particularly in terms of texture and performance.
Given their water-solubility and effective cleansing properties, isethionates are commonly used in rinse-off products that can be easily washed away with water.
Isethionate Powder, often called baby foam, is a specialty anionic powder surfactant made from all vegetable, renewable resources, primarily coconut.
Isethionate is used to impart extra mildness, good after feel, and good foaming in many personal care and cleansing products.
Isethionate powder is an excellent foamer in hard or soft water.
Isethionate is a naturally-derived ingredient that comes from the fatty acids that are present in isethionic acid and coconut oil.
Isethionate is well-suited for cleansing products designed for delicate areas of the body, such as the face and intimate hygiene products, where gentle yet effective cleaning is essential.
Isethionate can help reduce the potential for skin and scalp irritation, making it a preferred choice for individuals with conditions like eczema, psoriasis, or sensitive skin.
Isethionate has good rinse-off properties, which means it can be easily and thoroughly washed away, reducing the likelihood of product residue buildup on the skin or hair.
In finished cosmetic products, Isethionate is typically used at low concentrations and is considered to have low toxicity, minimizing the risk of adverse effects when used as directed.
Isethionate contributes to the smooth and creamy texture of certain personal care products, enhancing the overall feel and application.
In some formulations, isethionates may contribute to stabilizing fragrances, ensuring that the desired scent is maintained throughout the product's shelf life.
The original synthesis of the Isethionate, involving the reaction of sulfur trioxide with ethanol, has largely been replaced by more advanced methods.
An alternative production method involves the hydrolysis of carbyl sulfate, which is derived from the sulfonation of ethylene.
Besides its excellent water solubility and long-lasting foam, this ingredient is an incredibly mild surfactant, making it suitable even for sensitive skin; Not to be confused with similar-sounding sodium lauryl sulfate.
Isethionate is a natural product, pH stable (from 4.5 to 8.5). and is considered to be one of the safest on the market.
Commonly used in personal care products, sodium isethionate provides mild cleansing and lathering properties.
Isethionate is a specific type of isethionate surfactant that is often used in shampoos, body washes, and facial cleansers.
Derived from coconut oil, Isethionate is another variant used in cleansing products.
Isethionate is used as a fine white powder that has a mild scent.
Isethionate is a type of surfactant, which means it has the ability to lower the surface tension of liquids and enhance the spreadability of products.
This makes it useful for creating foaming and cleansing properties in various personal care products.
Uses Of Isethionate:
Isethionate's often used in shampoos to create a creamy lather that helps cleanse the hair and scalp without stripping away natural oils excessively.
This makes Isethionate suitable for daily use and for people with sensitive scalps.
Isethionates solid form makes it suitable for creating solid cleansing bars and shampoo bars, which are convenient for travel and reduce the need for liquid products.
Isethionate can be used in products designed to have a creamy and moisturizing texture, helping to create a balance between cleansing and hydration.
In makeup removers, Isethionate assists in breaking down makeup products while being gentle on the skin around the eyes and face.
Isethionate is used in shampoos to create a rich lather, cleanse the hair and scalp, and remove dirt and excess oils.
Isethionate's found in body washes and shower gels to provide a foamy lather and gentle cleansing for the skin.
Isethionate can be found in natural, organic, and sulfate-free formulations as a milder alternative to traditional sulfate-based surfactants.
In body washes and shower gels, Isethionate produces a luxurious foam that effectively cleanses the skin without leaving it dry or irritated.
Isethionate's used in facial cleansers to remove makeup, dirt, and impurities from the skin while maintaining a gentle cleansing experience.
Isethionate is commonly used in shampoos to provide gentle cleansing for the hair without stripping away natural oils excessively.
In body washes and shower gels, isethionates contribute to a creamy lather, making the cleansing experience luxurious and mild on the skin.
Isethionates are included in facial cleansers to ensure effective removal of impurities from the face without causing irritation.
Due to their mild nature, isethionates are often used in baby shampoos, washes, and other skincare products catering to the delicate skin of infants.
Isethionates are key ingredients in syndet bars, synthetic detergent bars that serve as alternatives to traditional soap bars.
These bars offer a milder cleansing experience.
Formulations for cleansing wipes may include isethionates to provide convenient and effective cleaning on the go.
In liquid hand soaps and liquid body washes, isethionates contribute to the formation of a rich lather and effective cleansing.
Isethionates may be included in certain hair conditioners, contributing to the conditioning effect while maintaining a gentle cleansing action.
In some skincare formulations, isethionates may be used to provide mild cleansing properties in cream or lotion-based products.
Isethionate is used in facial cleansers to remove makeup, dirt, and oils from the face without causing irritation.
Isethionate's included in bar soaps to enhance lathering and cleansing properties.
In cream-based cleansers, Isethionate helps to emulsify and remove makeup and impurities from the skin.
Isethionate is used in baby shampoos, body washes, and other baby care products for gentle cleaning.
Products designed for sensitive skin often contain Isethionate due to its mild and non-irritating properties.
Isethionate is used in solid shampoo bars, creating a lather and effectively cleansing the hair.
In some toothpaste formulations, Isethionate acts as a foaming agent to enhance texture and user experience.
Isethionate's often used in shaving creams and foams to create a smooth and comfortable shaving experience, reducing irritation and razor burn.
Due to its mild nature, Isethionate's used in products for individuals with sensitive or easily irritated scalps, such as dandruff shampoos and scalp treatments.
Products formulated for individuals with sensitive skin often include isethionates as they are considered gentler compared to some traditional surfactants.
Hand wash formulations may include isethionates to provide effective cleansing while being mild on the hands.
Isethionates contribute to the formulation of bubble baths, creating a foamy and enjoyable bathing experience.
Some intimate hygiene products may include isethionates to provide a mild and gentle cleansing experience for sensitive areas.
In makeup remover formulations, isethionates can help in effectively removing makeup without causing irritation to the skin.
As consumer preferences shift towards ethical and natural products, isethionates may be included in formulations that emphasize sustainability and gentleness.
Isethionate can be used alone or with other surfactants.
Heating is not necessary, but Isethionate dissolves quite poorly in water.
Therefore, in most cases you can only use about 3-6% in your shampoo
In exfoliating cleansers, isethionates may be incorporated to provide both cleansing and exfoliation benefits, helping to remove dead skin cells gently.
Isethionates are utilized in anti-dandruff shampoos for their ability to cleanse the scalp effectively while being mild and gentle.
Some hair masks or treatments may include isethionates to offer a combination of deep conditioning and mild cleansing.
In certain sunscreen formulations, isethionates may be included to provide a mild cleansing component, especially in products designed for water resistance.
Isethionates contribute to the formulation of creamy and luxurious cleansing foams, providing an indulgent cleansing experience.
Due to their sulfate-free nature, isethionates are commonly used in formulations for sulfate-free or low-sulfate products, meeting the demand for milder alternatives.
Isethionates are often included in pH-balanced products to maintain the acidity level suitable for the skin and hair, preventing over-drying.
Compact and effective, isethionate-containing products are often found in travel-sized packaging, offering convenience for on-the-go cleansing.
In certain hand sanitizers, isethionates may be added to provide mild cleansing properties along with the antimicrobial effects of the sanitizer.
Isethionates can be used in the formulation of foaming bath oils, contributing to a luxurious bath experience while cleansing and moisturizing the skin.
Formulations for refreshing body washes may include isethionates to provide an invigorating and cleansing sensation during use.
Some pet shampoos use isethionates to provide a gentle and effective cleansing experience for the fur and skin of pets.
In leave-in hair products like detanglers or conditioning sprays, isethionates may be included for their mild cleansing properties.
Foaming hand cleansers, designed for quick and convenient hand cleansing, may contain isethionates for their foaming and mild cleansing capabilities.
Isethionate can contribute to the formulation of gentle exfoliating products that help remove dead skin cells without being overly abrasive.
Some pre-shave products, such as foams or gels, may incorporate isethionates to provide a mild and lubricating base for smoother shaving.
Isethionates may be used in cleansing conditioners, offering a dual-action product that cleanses the hair while providing conditioning benefits.
In oil-based cleansers, isethionates can be included to enhance the cleansing properties and facilitate the removal of makeup and impurities.
Foaming facial cleansers often contain isethionates to provide a lightweight and airy foam, ensuring effective yet gentle cleansing.
Formulations for shower foams may include isethionates to create a refreshing and invigorating cleansing experience.
In products designed to remove hair color, isethionates can aid in the gentle removal of color without causing excessive damage to the hair.
Isethionates may be included in clarifying shampoos to effectively remove product buildup and impurities without stripping the hair.
In body scrubs, isethionates can be used to create formulations that exfoliate the skin gently, leaving it smooth and refreshed.
Foaming hand wash formulations may utilize isethionates for their foaming properties and mild cleansing capabilities.
Some waterless cleansing products, such as cleansing wipes or foams, may contain isethionates for effective on-the-go cleansing.
Products designed to clean makeup brushes may include isethionates for their ability to remove makeup residues gently.
In scalp treatments or tonics, isethionates can contribute to formulations that refresh the scalp without causing irritation.
Products that undergo dermatological testing for sensitivity and mildness may include isethionates in their formulations.
Isethionates can be used in the formulation of cleansing balms, providing a gentle and effective way to remove makeup and impurities.
More is possible (up to about 15%), but then the end result is opaque.
In solutions it is recommended to use Isethionate around a neutral pH of 6-8. Incidentally, the pH of a solution of Isethionate can be somewhat lower, it is recommended to increase it by adding sodium bicarbonate, for example.
Isethionate is a reactant in the synthesis of 4-substituted-2,3,5,6-tetrafluorobenezenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.
Isethionate is used as a starting material in the industrial production of taurine.
Isethionate is used in “combo bar” applications at levels of 2 – 60% to provide lathering in hard or soft water similar to soaps in soft water.
Isethionate is dense lather is additive to that of soap. Such mixtures are mild to the skin and are relatively non-drying.
Isethionate is recommended for use in bubble baths as a high-foaming agent.
Isethionate provides longer-lasting suds, even in the presence of soap, and is mild to the skin.
Safety profile Of Isethionate:
Isethionate is considered to be more biodegradable compared to some other surfactants, its impact on the environment can still vary depending on factors such as formulation, usage, and disposal.
Some individuals may be sensitive or allergic to certain ingredients, including isethionates.
If skin irritation or rash occurs, discontinue use and consult a healthcare professional.
While personal care products are typically used in well-ventilated areas, prolonged and direct inhalation of concentrated vapors or mists should be avoided.
Personal care products are not meant to be ingested.
Ingesting these products, even in small amounts, can be harmful.
If ingested, seek medical attention immediately.
While isethionates are considered biodegradable, Isethionate's essential to follow proper disposal guidelines for personal care products to minimize environmental impact.
The safety of a product depends on its overall formulation and the specific concentrations of each ingredient.
Always follow usage instructions provided by the manufacturer.
Some ingredients may interact with isethionates, affecting their stability or performance.
Formulators should consider the compatibility of isethionates with other ingredients in a formulation.
Avoid contact with eyes, as isethionates can cause eye irritation.
In case of eye contact, rinse thoroughly with water.
If irritation persists, seek medical attention.
Isethionate is generally mild, some individuals may be sensitive or allergic to it.
Patch testing should be performed when formulating products, especially for individuals with known skin sensitivities.
