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Isocil MW-14 is a high performance biocide for preserving metal working fluids, metal cleaning fluids, hydraulic Fluids, electrodeposition systems, polymer emulsions, natural latex, pigment dispersions, mineral slurries, paints, coatings and adhesives. It has extremely broad spectrum activity, controlling bacteria, fungi and yeasts while being compatible with most components in a formulation. Very low use levels make this product one of the most cost effective solutions on the market.
Chemical Composition
Isocil MW-14 is comprised of two primary active compounds, 5-chloro-2-methyl-4-isothiazolin-3- one and 2-methyl-4-isothiazolin-3-one, in a dilute aqueous solution that permits easy and safe handling.
Active Ingredients (nominal) WT/WT
5-Chloro-2-methyl-4-isothiazolin-3-one % 10.80%
2-Methyl-4-isothiazolin-3-one 3.83%
Total active ingredients 14.63%
Inert Ingredients % WT/WT
Magnesium salts (As Mg(NO3)2 ~23%
Water ~63%
Typical Properties
Appearance: Clear Liquid
pH: 2-4
Odor: Mild
Compatibility
Isothiazolinones are generally compatible with most components of industrial formulations. However, the presence of a few agents will cause degradation of the active ingredients (and therefore some care is necessary). Agents such as thiols, mercaptans, secondary amines, sulfides and other nucleophiles are to be avoided in formulations. Conditions of high heat for long periods of time ( > 50C) and pH above 9 will lead to loss of activity.
Biocidal Performance
Isocil MW-14 isothiazolinone is a more cost effective biocide preservative due to the extremely low use levels required. While the specific use levels are application dependent, the following MIC values for isothiazoline activities are indicative of the effectiveness of the product.
Bacteria ATCC No. PPM, Isothiazoline 1.5% Active
Gram-Negative
Achromobacter parvulus 4335 300
Alcaligenes faecalis 8750 300
Enterobacter aerogenes 3906 600
Escherichia coli 11229 600
Flavobacterium suaveolens 958 600
Klebsiella pneumoniae 13883 600
Proteus vulgaris 8427 600
Pseudomonas aeruginosa 15442 600
Pseudomonas cepacia 25416 600
Pseudomonas fluorescens 13525 600
Pseudomonas oleoverans 8062 300
Bacteria ATCC No. PPM, Isothiazoline 1.5% Active
Brevibacterium ammoniagenes 6871 600
Bacillus cereus 11778 600
Bacillus subtilis 6633 600
Sarcina lutea 9341 600
Staphylococcus aureus 6538 750
Staphylococcus epidermidis 155 600
Staphylococcus agalactiae 624 600
Yeast ATCC No. PPM, Isothiazoline 1.5% Active
Candida albicans 11651 600
Rhototorula rubra 9449 600
Saccharomyces cerevisiae 2601 600
Fungi ATCC No. PPM, Isothiazoline 1.5% Active
Asperigillus niger 9642 >750
Asperigillus oryzae 10196 750
Chaetomium globosum 6205 600
Gliocladium fimbriatum 32913 >750
Mucor rouxii 24905 >750
Penicillium funciculosum 9644 750
Pullularia (Aureobasidium)
pullulans 9348 >750
Rhizopus stolonifer 10404 750
Safety and Handling
Isothiazolinones at 14% active, are corrosive and potential skin sensitizers. As such, keeping these solutions away from the skin is essential. Due diligence must be maintained at all times while handling these materials. When working with Isocil MW-14, ensure that workers will not come in direct contact with the product. Proper selection of personal protective equipment is essential. Even if the slightest spill were to be absorbed onto a worker’s clothing, it may work its way through and cause a delayed skin burn. If significant aerosolization is expected, then the appropriate self contained breathing apparatus is required.
Regulatory Information
EPA Reg. No. 6836-240
