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CAS number:123-51-3
EC Number:204-633-5
EC index number:603-006-00-7
RTECS Number:EL5425000
IUPAC Name: 3-methylbutan-1-ol
isopentyl alcohol = 3-methyl-1-butanol= isoamyl alcohol = iso pentanol
Molecular Formula:C5H12O
Molecular Weight (g/mol):88.15
Density: 0.800g/mL
Auto-ignition temperature: 644 F
Appearance: Clear, colorless liquid
Melting point: −117°C (−179 °F; 156 K)
Boiling point: 131.1 °C (268.0 °F; 404.2 K)
Solubility in water: Slightly soluble, 28 g/L
Color: Colorless
Applications
Isopentyl alcohol is one of the several isomers of amyl alcohol and the main ingredient in the production of banana oil.
Isopentyl alcohol is not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package.
Isopentyl alcohol is one of the components of the aroma of Tuber melanosporum, the black truffle.
Isopentyl alcohol has been identified as a chemical in the pheromone used by hornets to attract other members of the hive to attack.
Isopentyl alcohol is an ingredient in the production of banana oil, an ester found in nature and also produced as a flavouring in industry.
Isopentyl alcohol is also an ingredient of Kovac's reagent, used for the bacterial diagnostic indole test.
İsopentyl alcohol is used:
-in pharmaceutical industry
-as biochemical reagent
-flavouring agent
-in nucleic acid purification with phenol and chloroform
-as a solvent in the manufacture of photographic chemicals
-Metallurgical Industry
-Spices Industry
Isoamyl alcohol or Isopentanol, also known as isopentyl alcohol or iso-amylalkohol, belongs to the class of organic compounds known as primary alcohols.
Primary alcohols are compounds comprising the alcohol functional group, attached to a primary carbon, with the general structure RCOH (R=alkyl, aryl).
Isoamyl alcohol is a very hydrophobic molecule, practically insoluble in water but readily soluble in organic solvents such as methanol, ethanol and ethyl acetate.
Thus, isopentanol is considered to be a fatty alcohol lipidic molecule.
Isopentyl alcohol is one of several isomers of amyl alcohol.
isopentyl alcohol is a by-product of gut microbial fermentation (PMID: 17452087).
Isopentanol is an alcoholic, banana, and burnt tasting compound. Due to its flavour and aroma, it is an ingredient in the production of banana oil, an ester found in nature and also produced as a flavouring in industry.
isopentyl alcohol can be produced by 3-methylbutanal reductase (EC 1.1.1.265) from 3-methylbutanal.
In alcoholic beverages, isopentyl alcohol is also the major higher chain alcohol and it is present in cider, mead, beer, wine, and spirits to varying degrees, being a product of the fermentation of starches.
Isopentanol has been shown to induce expression of CYP3A and CYP2E1 in human liver.
isopentyl alcohol is an primary alcohol that is butan-1-ol in which a hydrogen at position 3 has been replaced by a methyl group.
isopentyl alcohol has a role as a xenobiotic metabolite, a Saccharomyces cerevisiae metabolite and an antifungal agent.
isopentyl alcohol is a primary alcohol, a volatile organic compound and an alkyl alcohol. It derives from a hydride of an isopentane.
Isopentyl alcohol is a colorless liquid with the formula C5H12O, specifically (H3C–)2CH–CH2–CH2–OH.
Isopentyl alcohol is one of several isomers of amyl alcohol (pentanol).
Isopentyl alcohol is also known as isoamyl alcohol, isopentanol, or (in the IUPAC recommended nomenclature) 3-methyl-butan-1-ol.
An obsolete name for it was isobutyl carbinol.
Besides its use in the synthesis of banana oil, isopentyl alcohol is also an ingredient of Kovac's reagent, used for the bacterial diagnostic indole test.
Isopentyl alcohol can be synthesized by condensation of isobutene and formaldehyde which produces isoprenol and hydrogenation.
Isopentyl alcohol is a colourless liquid of density 0.8247 g/cm3 (0 °C), boiling at 131.6 °C, slightly soluble in water, and easily dissolved in organic solvents.
Isopentyl alcohol has a characteristic strong smell and a sharp burning taste.
Amyl alcohol has an oral LD50 of 200 mg/kg in mice, suggesting that it is significantly more toxic than ethanol.
On passing the vapour through a red-hot tube, Isopentyl alcohol decomposes into acetylene, ethylene, propylene, and other compounds.
isopentyl alcohol is oxidized by chromic acid to isovaleraldehyde, and it forms addition compounds crystals with calcium chloride and tin(IV) chloride.
isopentyl alcohol is also used as an antifoaming agent in the chloroform isoamyl alcohol reagent.
Isopentyl alcohol can be separated from fusel oil by either of two methods: shaking with strong brine solution and separating the oily layer from the brine layer; distilling it and collecting the fraction that boils between 125 and 140 °C.
Further purification is possible with this procedure: shaking the product with hot limewater, separating the oily layer, drying the product with calcium chloride, and distilling it, collecting the fraction boiling between 128 and 132 °C
isopentyl alcohol is used in a phenol–chloroform extraction mixed with the chloroform to further inhibit RNase activity and prevent solubility of RNAs with long tracts of poly-adenine.
isopentyl alcohol is an ingredient in the production of banana oil, an ester found in nature and also produced as a flavouring in industry.
isopentyl alcohol is a common fusel alcohol, produced as a major by-product of ethanol fermentation.
Isopentyl alcohol is one of the flavour and fragrance chemicals.
Isopentyl alcohol is a speciality solvent often noted for its distinctive odour – which smells like pear drops.
Isopentyl alcohol is a speciality solvent that finds extensive use for flavours and fragrances and is used in the production of many synthetic flavours.
Isopentyl alcohol's relatively low eco-tox profile finds it use growing in other areas.
Isopentanol, also known as isoamyl alcohol or 3-methylbutanol, belongs to the class of organic compounds known as primary alcohols.
Primary alcohols are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).
Thus, isopentanol is considered to be a fatty alcohol lipid molecule.
Isopentanol is a very hydrophobic molecule, practically insoluble in water, and relatively neutral.
Isopentanol exists in all eukaryotes, ranging from yeast to humans.
Isopentanol is an alcoholic, banana, and burnt tasting compound. Isopentanol is found, on average, in the highest concentration within milk (cow).
Isopentanol has also been detected, but not quantified, in several different foods, such as chinese cinnamons, grapefruits, walnuts, wild leeks, and spearmints.
This could make isopentanol a potential biomarker for the consumption of these foods.
Isopentanol is one of several isomers of amyl alcohol. Isopentanol is the major higher chain alcohol in alcoholic beverages and is present in cider, mead, beer, wine, and spirits to varying degrees, being obtained by the fermentation of starches. Isopentanol, with regard to humans, has been found to be associated with the diseases such as ulcerative colitis; isopentanol has also been linked to the inborn metabolic disorder celiac disease.
Isopentanol is a metabolite found in Escherichia.
Isopentyl alcohol is used as a solvent for the preparation of synthetic fruit flavours, such as apricot, banana, cheery, greengage, malt, orange, plum and whiskey flavours, and is a raw material in the production of synthetic banana oil.
Isopentyl alcohol is one of the components of the aroma of the black truffle.
Isopentyl alcohol is also used for estimation of fat in milk and milk products.
Isopentyl alcohol is the main ingredient of Kovac’s Reagent used for the bacterial diagnostic Indole Test.
Isopentyl alcohol blend of properties makes it suitable for use as a foam suppressant, affecting the surface tension of micro-emulsions and causing foam breaking.
As a solvent, isopentyl alcohol is finding increasing use in a wide number of industrial applications.
In solvency power, it falls between common hydrocarbon solvents and lower molecular weight ketones.
Paraffin wax is soluble in hot isopentyl alcohol.
In formulation, some high molecular weight esters and polar plastics incorporate isopentyl alcohol-based systems e.g. cellulose esters.
Shellac and urea formaldehyde.
Major companies profiled in the global Isopentyl Alcohol market are:
Petrom
Oxiteno
BASF
Chemoxy
Alfrebro
Oxea-Chemicals
Nimble Technologies
Shandong Junan Kaili Chemical
Yancheng Hongtai Bioengineering
Shandong Hongyuan Chemical
Sanjiang Chemical
Baohua Chemical
Following are the major regions considered for the analysis of the isopentyl alcohol market:
-North America (United States, Canada and Mexico)
-Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
-Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
-South America (Brazil, Argentina, Colombia, and Rest of South America)
-Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa
It is a diluent in some printing inks, lacquers and gums.
In pharmaceuticals, isopentyl alcohol is the initial raw material for a number of drug preparations such as Barbamil, Validol, Corvalol and Isoamyl nitrite.
A derivative of Isopentyl alcohol, the p-methoxycinnamate is used as a UV absorber in some cosmetic formulations, and the product itself finds application as a cosmetic flavouring and in perfume.
Isopentyl Alcohol is designated as Molecular Biology grade and is suitable for use in nucleic acid purification.
Isopentyl Alcohol, commonly called isoamyl alcohol,is routinely used in molecular biology, notably in the purification of DNA.
Isopentyl Alcohol is widely used in conjunction with phenol and chloroform, for the removal of proteins from the nucleic acid solutions by extraction.
The addition of chloroform and Isopentyl Alcohol in the extraction protocol deals with two issues that the use of phenol alone does not completely address.
Isopentyl Alcohol helps to inhibit RNase activity, which phenol does not completely inhibit.
Isopentyl Alcohol helps to prevent the solubilization in the phenol phase of long RNA molecules with long poly(A) portions.
In addition, Isopentyl Alcohol reduces foaming during the extraction process.
Isopentyl Alcohol may also be used in the extraction of ethidium bromide from DNA solutions and in the radiolabeling of RNA transcripts in nuclei that have been isolated from tissue.
Isopentyl Alcohol is often used in the HPLC analysis of various pharmaceuticals and metabolites.
Isopentyl Alcohol has been used in the analysis of oxidized and reduced pyridine nucleotides and adenylates in organic phenol extracts from mitochondria.
A phenol,chloroform,Isopentyl Alcohol procedure for the extraction of chloroplast DNA that avoids density gradient differential centrifugation has been published.
A protocol for the isolation of mRNA from a thermophilic cyanobacterium that incorporates a phenol,chloroform, isopentyl alcohol mixture has been described.
Isopentyl alcohol is an primary alcohol that is butan-1-ol in which a hydrogen at position 3 has been replaced by a methyl group.
Isopentyl alcohol has a role as a xenobiotic metabolite, a Saccharomyces cerevisiae metabolite and an antifungal agent.
Isopentyl alcohol is a primary alcohol, a volatile organic compound and an alkyl alcohol.
Isopentyl alcohol derives from a hydride of an isopentane.
Isopentanol, also known as isopentyl alcohol or 3-methylbutanol, belongs to the class of organic compounds known as primary alcohols.
Primary alcohols are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).
Thus, isopentyl alcohol is considered to be a fatty alcohol.
Isopentyl alcohol is a cyanobacterial volatile organic compound that has been identified as one of the main aroma/flavor constituents in banana fruit, karanda fruits and in whey spirit.
Isopentyl alcohol exists in all eukaryotes, ranging from yeast to plants to humans.
In yeast, isopentyl alcohol is involved in the metabolic pathway called the leucine degradation pathway.
Based on a literature review a significant number of articles have been published on isopentyl alcohol.
Isopentyl alcohol is a solvent for resins and fats.
Isopentyl alcohol is slightly soluble in water, miscible with alcohol, ether, benzene, chlorofom.
Isopentyl alcohol is moderately toxic.
Isopentyl alcohol is Colorless liquid with a mild, choking alcohol odor.
Isopentyl alcohol is Less dense than water, soluble in water. Hence floats on water.
Isopentyl alcohol produces an irritating vapor.
Isopentyl alcohol is a primary pentyl alcohol (CH3)2CHCH2CH2OH that has a disagreeable odor and pungent taste and is obtained from fusel oil; 3-methyl-1-butanol
Isopentyl alcohol attacks plastics.
Mixtures of Isopentyl alcohol with concentrated sulfuric acid and strong hydrogen peroxide may cause explosions.
Mixing Isopentyl alcohol with hypochlorous acid in water or water/carbon tetrachloride solution can generate isoamyl hypochlorites, which may explode, particularly on exposure to sunlight or heat.
Mixing Isopentyl alcohol with chlorine would also yield isoamyl hypochlorites.
Base-catalysed reactions of Isopentyl alcohol with isocyanates can occur with explosive violence.
Isopentyl alcohol is a speciality solvent that finds extensive use for flavours and fragrances and is used in the production of many synthetic flavours.
Isopentyl alcohol's relatively low eco-tox profile finds it use growing in other areas.
Safe Use and Handling:
For specific safe use and handling information, or to obtain the Isopentyl alcohol Safety Data Sheet, contact your local representative.
Shelf Life:
An approximate shelf life of Isopentyl alcohol is 2 years, if Isopentyl alcohol is stored in the original container, kept tightly closed in a well-ventilated location. As storage and local ambient conditions vary and has no control over the practices, procedures and conditions at your or other locations, the shelf life estimate provided here should be used as guidance only.
It is not provided as a guarantee of any shelf life.
Isopentyl alcohol is used as a solvent for the preparation of synthetic fruit flavours, such as apricot, banana, cheery, greengage, malt, orange, plum and whiskey flavours, and is a raw material in the production of synthetic banana oil.
Isopentyl alcohol is one of the components of the aroma of the black truffle. It is also used for estimation of fat in milk and milk products.
Isopentyl alcohol is the main ingredient of Kovac’s Reagent used for the bacterial diagnostic Indole Test.
Isopentyl alcohol blend of properties makes it suitable for use as a foam suppressant, affecting the surface tension of micro-emulsions and causing foam breaking.
As a solvent, Isopentyl alcohol is finding increasing use in a wide number of industrial applications.
In solvency power, Isopentyl alcohol falls between common hydrocarbon solvents and lower molecular weight ketones.
Paraffin wax is soluble in hot Isopentyl alcohol.
In formulation, some high molecular weight esters and polar plastics incorporate Isopentyl alcohol-based systems e.g. cellulose esters.
Shellac and urea formaldehyde.
Isopentyl alcohol is a diluent in some printing inks, lacquers and gums.
In pharmaceuticals,Isopentyl alcohol is the initial raw material for a number of drug preparations such as Barbamil, Validol, Corvalol and amyl nitrite.
A derivative of Isopentyl alcohol, the p-methoxycinnamate is used as a UV absorber in some cosmetic formulations, and the product itself finds application as a cosmetic flavouring and in perfume.
Isopentyl alcohol is a clear, colorless, liquid organic compound that is one of several isomers of amyl alcohol.
Isopentyl alcohol is a principal ingredient in the production of banana oil, a natural ester used in the flavoring industry.
Isopentyl alcohol is also used as an antifoaming agent in the Chloroform: Isomyl Alcohol reagent.
Isopentyl alcohol is one of several isomers of amyl alcohol.
Isopentyl alcohol is an ingredient in the production of banana oil, an ester found in nature and also produced as a flavouring in industry.
Isopentyl alcohol and acetic acid were reacted using the process of esterification to produce an ester, isopentyl acetate.
The starting materials were reacted using conditions specific to the reaction being performed and some of the target product was obtained in 25.6% yield.
The method in which this reaction took place was esterification, where water was removed to force the reaction to move toward its products, an ester and water.
The products were analyzed by observing the odor and infrared spectroscopy (IR).
The odor of the product appeared to be banana-like, closely resembling the smell of the candy banana.
This smell is indicative of an ester, specifically isopentyl acetate.
