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Isopropanolamine (Monoisopropanolamine) is a versatile amino alcohol.
Isopropanolamine (Monoisopropanolamine) is extensively used across multiple industries including coatings, metalworking, agrochemicals as well as personal care.
Isopropanolamine (Monoisopropanolamine)s combination of neutralizing strength, emulsification capability, corrosion inhibition as well as solvent properties makes it a valuable intermediate as well as functional additive.
CAS Number: 68003-13-4
Molecular Formula: C3H12BNO4
Molecular Weight: 136.94
EINECS Number: 268-109-8
Synonyms: isopropanolamine myristate, 64012-06-2, UOF9788283, MIPA-MYRISTATE, EINECS 264-601-1, MONOISOPROPANOLAMINE MYRISTATE, 2-PROPANOL, 1-AMINO-, TETRADECANOATE (SALT), MIPA-MYRISTATE [INCI], (2-Hydroxypropyl)ammonium myristate, UNII-UOF9788283, SCHEMBL1960959, DTXSID70981958, HRTFUMOKDUHNIY-UHFFFAOYSA-N, Tetradecanoic acid--1-aminopropan-2-ol (1/1), Q27291176, (2-hydroxypropyl)ammonium dihydrogen orthoborate, MIPA-BORATE, ethyl 2-amino-5-[(4-amino-3-methoxyphenyl)methyl]benzoate, Boric acid (H3BO3), compd. with 1-amino-2-propanol (1:1), 2-Hydroxypropylammonium orthoborate, Boric acid, monoisopropanolamine salt, Einecs 268-109-8, Isopropanolamine borate
Isopropanolamine (Monoisopropanolamine) distinguishes itself from other ethanolamines with improved heat/color stability, enhanced oil solubility & also favorable physical handling characteristics—qualities that optimize product performance while keeping costs manageable.
Isopropanolamine (Monoisopropanolamine), also known as 1 amino 2 propanol (CAS Number 78 96 6), is a primary alkanolamine derived from isopropanol.
Isopropanolamine (Monoisopropanolamine) is a clear, colorless liquid with a mild ammonia like odor.
As the lowest molecular weight isomer among isopropanolamines, Isopropanolamine (Monoisopropanolamine) provides effective basicity—raising pH and neutralizing acids—while also functioning as a buffering agent and chemical intermediate.
Isopropanolamine (Monoisopropanolamine), is an organic chemical compound that belongs to the family of alkanolamines, which are molecules containing both alcohol (-OH) and amine (-NH₂) functional groups.
Structurally, it is a clear to slightly yellow, viscous liquid with a mild ammonia-like odor, and it is highly soluble in water as well as in many polar organic solvents.
Its chemical structure gives it a dual nature: the alcohol group imparts hydrophilic (water-attracting) properties, while the amine group makes it basic and capable of neutralizing acids.
Because of this unique combination of properties, Monoisopropanolamine is widely used as a pH adjuster, neutralizing agent, and emulsifier in a variety of industrial and consumer applications.
In chemical manufacturing, it can serve as an intermediate in producing surfactants, corrosion inhibitors, and agrochemicals.
Isopropanolamine (Monoisopropanolamine) also acts as a co-solvent in formulations where water and oil-based components need to be blended smoothly, such as in coatings, cleaning agents, and cosmetic products.
Isopropanolamine (Monoisopropanolamine) serves as an emulsifier and stabilizer, improving oil solubility, foam control, and color stabilization in formulations.
It’s frequently used to neutralize fatty acids as well as sulfonates.
Isopropanolamine (Monoisopropanolamine) is also used as a corrosion inhibitor in water based metalworking fluids as well as an intermediate in synthetic chemistry for foaming agents, herbicides, coatings & also surfactants.
Compared to conventional ethanolamines, Isopropanolamine (Monoisopropanolamine) offers superior thermal as well as oxidative stability.
This makes it ideal for demanding processing conditions.
Isopropanolamine (Monoisopropanolamine)’s also valued for helping formulate more strong items with improved low temperature performance as well as reduced discoloration.
Isopropanolamine (Monoisopropanolamine) is the organic compound with the formula CH3CH(OH)CH2NH2.
Isopropanolamine (Monoisopropanolamine) is an amino alcohol.
The term isopropanolamine may also refer more generally to the additional homologs diisopropanolamine (DIPA) and triisopropanolamine (TIPA).
Isopropanolamine (Monoisopropanolamine) is chiral.
It can be prepared by the addition of aqueous ammonia to propylene oxide.
A basic chemical used in many applications serving as an emulsifier, stabilizer, chemical intermediate, and a neutralizer that achieves basicity, buffering, and alkalinity objectives.
Isopropanolamine (Monoisopropanolamine) is a liquid product at room temperature, providing neutralization of acidic component and pH contribution to the formulations.
Isopropanolamine (Monoisopropanolamine)-based formulations can offer better color and heat stability and improved oil solubility than conventional ethanolamines.
Isopropanolamine (Monoisopropanolamine) is a specialty alkanolamine that acts as a neutralizers for water-based coatings
A colorless liquid with a slight ammonia-like odor less dense than water and soluble in water.
Produces toxic oxides of nitrogen during combustion used in plastics, paints, cutting oils, and specialized cleaning compounds.
Isopropanolamine (Monoisopropanolamine) is an aminoalcohol amines are chemical bases.
They neutralize acids to form salts plus water these acid-base reactions are exothermic.
The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Isopropanolamine (Monoisopropanolamine) is known for its ability to react with fatty acids to form amine salts, which are used as emulsifying and thickening agents in both industrial processes and personal care formulations.
Due to its basicity and surface activity, it plays an important role in adjusting formulation stability, foaming characteristics, and product performance in systems ranging from water-based paints to liquid detergents.
LogP: -0.961 (est)
EWG's Food Scores: 1-2
FDA UNII: YK5M7W95MC
Isopropanolamine (Monoisopropanolamine) or 1-amino-2-propanol, is an organic compound with the chemical formula CH3CH(OH)CH2NH2.
Isopropanolamine (Monoisopropanolamine) is a colorless, viscous liquid with an ammonia-like odor.
It contains both an amino group (-NH2) and a hydroxyl group (-OH), making it an alkanolamine.
Isopropanolamine (Monoisopropanolamine) is known by its abbreviated form MIPA, is a basic chemical that can be used in many applications to achieve basicity, buffering and alkalinity objectives.
They are good solubilizers of oil and fat, so they are used to neutralize fatty acids and sulfonic acid-based surfactants.
Isopropanolamine (Monoisopropanolamine) is one of the components incorporated in the biosynthesis of cobalamin.
The O-phosphate ester is produced from threonine by the enzyme Threonine-phosphate decarboxylase.
Isopropanolamine (Monoisopropanolamine), is a versatile organic compound that belongs to the class of alkanolamines, which are characterized by the presence of both an alcohol functional group and an amine functional group within the same molecule.
This dual functionality imparts a unique combination of chemical reactivity and physical properties, allowing Isopropanolamine (Monoisopropanolamine) to behave simultaneously as a weak base, capable of neutralizing acids, and as a polar solvent that can interact with both hydrophilic and hydrophobic substances.
In its pure form, Isopropanolamine (Monoisopropanolamine) typically appears as a clear to pale yellow, viscous liquid with a faint, ammonia-like odor, and it exhibits complete miscibility with water as well as good solubility in many polar organic solvents.
These solubility characteristics make it highly adaptable in formulations where water and oil phases must be blended or stabilized.
Structurally, Isopropanolamine (Monoisopropanolamine) is a secondary amine with a hydroxyalkyl group, which enables it to participate in both hydrogen bonding and acid-base reactions, making it highly valuable as a pH regulator, emulsifier, and chemical intermediate.
Due to these properties, Isopropanolamine (Monoisopropanolamine) finds extensive use across multiple industries.
In the chemical manufacturing sector, it is widely employed in the synthesis of surfactants, emulsifying agents, and corrosion inhibitors, while in coatings and paints it serves as a neutralizing agent that also enhances dispersion stability.
In the cosmetics and personal care industry, it is used to adjust the pH of formulations, improve emulsification, and enhance the texture of creams, lotions, and hair-care products.
Furthermore, Isopropanolamine (Monoisopropanolamine) can react with fatty acids to form amine soaps, which are stable emulsifiers used in both industrial and household cleaning products.
Its reactivity profile also makes it a valuable raw material in agrochemical production, where it functions as a solubilizing or neutralizing component in herbicides and pesticide formulations, helping active ingredients remain stable and effective over time.
In addition, Isopropanolamine (Monoisopropanolamine)’s amphiphilic nature — having both water-attracting and oil-attracting ends — allows it to bridge otherwise incompatible substances, making it indispensable in systems that require stable, uniform mixtures.
Uses:
Synthetic and semisynthetic machine lubricating/cutting oil formulations have included isopropanolamine, diisopropanolamine, and triethanolamine, together with nitrites, consequently the EPA has promulgated standards regarding the composition of cutting fluids.
Isopropanolamine (Monoisopropanolamine) is used to study the effect of temperature and water content on the molecular structure and hydrogen bonding of amino-2-propanol, which has been examined by Fourier transform near-infrared (FT-NIR) spectroscopy.
Also used in used in the synthesis of protein kinase CK2 inhibitors used in the treatment of neoplasia and other infective diseases.
The isopropanolamines are used as buffers.
They are good solubilizers of oil and fat, so they are used to neutralize fatty acids and sulfonic acid-based surfactants.
Isopropanolamine (Monoisopropanolamine) is typically used in metalworking fluid, waterborne coatings, personal care products, and in the production of titanium dioxide and polyurethanes.
Isopropanolamine (Monoisopropanolamine) is an intermediate in the synthesis of a variety of pharmaceutical drugs.
Isopropanolamine (Monoisopropanolamine) is metabolised to aminoacetone by the enzyme (R)-aminopropanol dehydrogenase.
Used as an emulsifier, stabilizer, chemical intermediate, and a neutralizer in personal care, pharmaceuticals, metalworking products, and water borne coatings. Possesses acid neutralization.
Isopropanolamine (Monoisopropanolamine), is valued for its unique combination of an alcohol group and an amine group within the same molecule, a structural feature that allows it to perform several different chemical and physical roles in various industrial and commercial applications.
One of its most common uses is as a neutralizing agent in formulations containing acidic components, such as coatings, paints, inks, and adhesives, where it helps control pH, improve product stability, and prevent unwanted corrosion in metal packaging or application equipment.
In the cosmetics and personal care industry, Isopropanolamine (Monoisopropanolamine) is widely incorporated into creams, lotions, hair conditioners, and shaving products, where it functions not only as a pH adjuster but also as an emulsifying aid that stabilizes mixtures of water and oils, thereby improving the texture, consistency, and shelf-life of the product.
When reacted with fatty acids such as myristic acid or lauric acid, Isopropanolamine (Monoisopropanolamine) produces amine soaps, which are highly effective emulsifiers and foaming agents in both skin-care products and household cleaning formulations.
In the industrial cleaning sector, Isopropanolamine (Monoisopropanolamine) is often used in degreasers, detergents, and all-purpose cleaners, where its surfactant-forming ability enhances the removal of oils, greases, and particulate soils from hard surfaces.
Its capacity to improve the wetting of surfaces and to reduce surface tension makes it particularly effective in cleaning metal machinery, automotive parts, and food processing equipment.
The agrochemical industry makes extensive use of Isopropanolamine (Monoisopropanolamine) as a neutralizing or solubilizing agent in the preparation of herbicide and pesticide formulations.
By forming water-soluble salts with acidic active ingredients, Isopropanolamine (Monoisopropanolamine) helps these chemicals dissolve evenly in spray solutions, ensures a more uniform distribution over crop surfaces, and enhances their chemical stability during storage.
In addition, Isopropanolamine (Monoisopropanolamine) serves as a chemical intermediate in the production of corrosion inhibitors, cement grinding aids, textile finishing agents, and water treatment chemicals.
In cement grinding, for example, small amounts of MIPA can be added to milling operations to prevent particle agglomeration, improve flow characteristics, and increase overall grinding efficiency.
In metalworking fluids, Isopropanolamine (Monoisopropanolamine)-based additives help reduce friction, protect against rust, and extend the lifespan of cutting tools.
The combination of these properties — pH control, emulsification, solubilization, and chemical reactivity — makes Monoisopropanolamine a multipurpose ingredient that bridges the needs of industries as varied as personal care, agriculture, coatings, and heavy manufacturing, often allowing for the reduction or replacement of multiple separate additives in a single, cost-effective formulation.
Safety Profile:
Isopropanolamine (Monoisopropanolamine) can pose a variety of health, safety, and environmental hazards if it is not handled properly, primarily because it is both an amine and an alcohol, giving it reactive and irritating characteristics that can affect the skin, eyes, respiratory tract, and aquatic life.
In its pure form or in concentrated solutions, Isopropanolamine (Monoisopropanolamine) is strongly alkaline and can cause chemical burns or severe irritation to the skin upon direct contact, particularly if exposure is prolonged or occurs on sensitive or damaged skin.
Even short-term skin exposure can lead to redness, itching, and dryness, and in some cases, dermatitis can develop from repeated or chronic contact.
When Isopropanolamine (Monoisopropanolamine) comes into contact with the eyes, it can produce serious irritation, pain, watering, and redness, and higher concentrations have the potential to cause long-lasting damage to the corneal surface, resulting in blurred vision or other visual disturbances.
Inhalation of Isopropanolamine (Monoisopropanolamine) vapors, mists, or aerosols, especially in poorly ventilated environments or during industrial processing, can irritate the nose, throat, and lungs, causing coughing, sore throat, chest tightness, and in some cases, difficulty breathing.
Repeated inhalation over time may contribute to chronic respiratory irritation or sensitization in particularly sensitive individuals.
