CHEMICAL IDENTIFICATION & NOMENCLATURE
IUPAC Name: Propan-2-yl tetradecanoate
Common Name: Isopropyl myristate
Trade Names: IPM, Tegosoft M, Crodamol IPM, Dermol IPM
CAS Registry Number: 110-27-0
EC Number: 203-751-4
EINECS: 203-751-4
UN Number: Not regulated
Synonyms:
Isopropyl tetradecanoate,1-Methylethyl tetradecanoate,Tetradecanoic acid, 1-methylethyl ester,Myristic acid isopropyl ester,IPM
Chemical Family: Fatty acid ester emollient
Molecular Formula: C₁₇H₃₄O₂
Molecular Weight: 270.46 g/mol
Chemical Structure: CH₃(CH₂)₁₂COOCH(CH₃)₂
TECHNICAL FUNCTIONS
Primary Functions in Cosmetics:
1. Emollient (Primary Function):
Mechanism: Fills spaces between skin cells
Effect: Softening, smoothing, moisturizing
Spreadability: Excellent due to low viscosity
After-feel: Non-greasy, dry feel
2. Solubilizer/Cosolvent:
For lipophilic actives (vitamins, fragrances, sunscreens)
Enhances penetration of active ingredients
Improves stability of oil-soluble components
3. Viscosity Modifier:
Reduces viscosity of formulations
Improves pourability and spreadability
4. Carrier Oil:
For fragrances and flavors
In aromatherapy products
5. Plasticizer:
In nail polish and hair sprays
Improves flexibility of polymer films
Performance Advantages:
Low Comedogenicity: Non-pore clogging
Excellent Spreadability: Low surface tension
Good Skin Feel: Non-greasy, non-tacky
Compatibility: Wide range of cosmetic ingredients
Stability: Chemically inert in most formulations
5. APPLICATIONS
Cosmetic & Personal Care (90% of consumption):
Application, Typical Concentration, Function
Skin Care, 2-15%, Emollient, solvent, carrier
- Moisturizers, 5-10%, Emollient, penetration enhancer
- Sunscreens, 10-20%, Solvent for UV filters
- Anti-aging, 2-8%, Carrier for actives
- Makeup removers, 10-30%, Solvent for makeup
Hair Care, 1-5%, Conditioner, shine enhancer
Color Cosmetics, 3-10%, Binder, emollient
- Lipsticks, 5-15%, Emollient, glossing agent
- Foundations, 2-8%, Spreadability, moisturizing
Deodorants/Antiperspirants, 2-8%, Emollient, solvent
Fragrances, 5-50%, Carrier/diluent
Baby Products, 2-8%, Mild emollient
Pharmaceutical Applications (8%):
Topical Formulations: Ointments, creams, gels
Transdermal Delivery: Penetration enhancer
Active Solubilization: For poorly soluble drugs
Injectable: Used in some parenteral formulations (high purity)
Industrial Applications (2%):
Lubricants: Light-duty lubricant, mold release agent
Plastics: Plasticizer for certain polymers
Textiles: Fiber lubricant, softening agent
Leather: Fatliquoring agent
Metalworking: Component of cutting oils
Specialty Grades:
Cosmetic Grade: High purity, low odor
Pharmaceutical Grade: USP/EP compliance
Technical Grade: For industrial applications
Organic Certified: From organic feedstocks
Formulation Guidelines:
Compatibility: Excellent with most cosmetic ingredients
Preservation: Does not support microbial growth
Oxidation: Add antioxidants if needed for long storage
Emulsification: Requires emulsifiers for water-containing systems
Temperature: Add at 40-60°C in emulsion preparation
SAFETY INFORMATION ABOUT ISOPROPYL MYRISTATE (IPM)
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:
If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.
In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.
Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.
Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.
Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.
If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product