PRODUCTS

ISOPROPYL PALMITATE (IPP)

CAS:   142-91-6
MF:   C19H38O2
MW:   298.5
EINECS:   205-571-1

Synonyms
kesscoipp;kesscoisopropylpalmitate;Lexol IPP;Liponate IPP;nikkolipp;Palmitic acid esters;Plymouth ipp;plymouthipp;ISOPROPYL PALMITATE;142-91-6;Isopropyl hexadecanoate;Hexadecanoic acid, 1-methylethyl ester;Isopalm;Emerest 2316;Wickenol 111;Deltyl;Isopal;Propal;Deltyl prime;Tegester isopalm;Ja-fa ippkessco;Sinnoester PIT;Crodamol IPP;Plymouth IPP;Starfol IPP;Unimate IPP;Kessco IPP;Emcol-IP;Isopropyl n-hexadecanoate;Nikkol IPP;Stepan D-70;Palmitic acid, isopropyl ester;1-Methylethyl hexadecanoate;Estol 103;Usaf ke-5;JA-FA Ipp;Kessco isopropyl palmitate;Hexadecanoic acid, isopropyl ester;propan-2-yl hexadecanoate;Hariol ipp;Palmitic Acid Isopropyl Ester;NSC 69169;Estol 1517;HSDB 2647;Tegosoft P;Liponate IPP;UNII-8CRQ2TH63M;EINECS 205-571-1;Lexol IPP;8CRQ2TH63M;MFCD00008993;NSC-69169;BRN 1786567;CHEBI:84262;2-propyl hexadecanoate;AI3-05733;Isopropyl palmitate (NF);Isopropyl palmitate [NF];DTXSID9027104;EC 205-571-1;4-02-00-01167 (Beilstein Handbook Reference);Isopropyl ester of hexadecanoic acid;NCGC00164128-01;WE(2:0(1Me)/16:0);DTXCID507104;ISOPROPYL PALMITATE (II);ISOPROPYL PALMITATE [II];ISOPROPYL PALMITATE (MART.);ISOPROPYL PALMITATE [MART.];ISOPROPYL PALMITATE (USP-RS);ISOPROPYL PALMITATE [USP-RS];ISOPROPYL PALMITATE (EP IMPURITY);ISOPROPYL PALMITATE [EP IMPURITY];CAS-142-91-6;ISOPROPYL PALMITATE (EP MONOGRAPH);ISOPROPYL PALMITATE [EP MONOGRAPH];iso-propylpalmitate;isopropyl-palmitate;Hexadecanoic acid 1-methylethyl ester;ISOPROPYLPALMITATE;Radia 7200;1-methylethyl hexandecanoate;SCHEMBL7743;Palmitic acid-isopropyl ester;Isopropyl palmitate, >=90%;CHEMBL139055;Hexadecanoic acid isopropyl ester;MSK1642;Hexadecanoic acid, 1-methyl ester;ISOPROPYL PALMITATE [HSDB];WLN: 15VOY1 & 1;ISOPROPYL PALMITATE [VANDF];NSC69169;Tox21_112085;Tox21_202558;ISOPROPYL PALMITATE [WHO-DD];LMFA07010675;AKOS015902011;Tox21_112085_1;1ST1642;CS-W012142;HY-W011426;NCGC00164128-02;NCGC00260107-01;BS-15396;Hexadecanoic acidisopropyl n-hexadecanoate;MSK1642-1000;Isopropyl palmitate, technical grade, 90%;DB-042654;NS00009869;P0005;1-Methylethyl ester1-methylethyl hexandecanoate;1ST1642-1000;D04632;SBI-0654057.0001;SR-01000944752;Isopropyl palmitate Solution in Acetone, 1000?g/mL;Q2631777;SR-01000944752-1;BRD-K30758549-001-01-8;Isopropyl palmitate Solution in Acetone, 1000mug/mL;Isopropyl hexadecanoate, European Pharmacopoeia (EP) Reference Standard;Isopropyl palmitate, United States Pharmacopeia (USP) Reference Standard;Isopropyl palmitate, Pharmaceutical Secondary Standard; Certified Reference Material
205-571-1

Isopropyl Palmitate (IPP) is a fatty acid ester and an isopropyl ester.
Isopropyl Palmitate (IPP) is functionally related to a hexadecanoic acid.
Isopropyl Palmitate (IPP) is an analog of isopropyl myristate and an aliphatic ester used as a flavoring ingredient in food industry.
Isopropyl Palmitate (IPP) is one of the volatile compounds found in Psidium salutare fruits and boiled buckwheat flour.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Isopropyl Palmitate (IPP) is the ester of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) is an emollient, moisturizer, thickening agent, and anti-static agent.
The chemical formula is CH3(CH2)14COOCH(CH3)2.

Isopropyl Palmitate (IPP) is a clear and colorless ingredient with a pleasant odor.
In cosmetics and personal care, Isopropyl Palmitate (IPP) is used primarily as an emollient that helps to soothe and soften the skin.
For this reason, Isopropyl Palmitate (IPP) is quite popular in products like moisturizers, lotions, and creams.
Additionally, Isopropyl Palmitate (IPP) is not a paraben and does not contain any preservatives that may be harmful to the skin.
Isopropyl Palmitate (IPP) is also beneficial in enhancing the texture of the products that it is added to.
The chemical formula of Isopropyl Palmitate (IPP) is C19H38O2.
Isopropyl Palmitate (IPP) by McKinley Resources acts as an emollient, moisturizer and thickening agent.
Isopropyl Palmitate (IPP) is a compound of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) contains fatty acid, composed of vitamin A and an antioxidant.
Isopropyl Palmitate (IPP) can easily penetrate the skin and offers softness and suppleness.
Isopropyl Palmitate (IPP) is used in moisturizers, lipstick, facial treatments, eye shadow, hair conditioner, styling gel, concealer, foundation, lip gloss and anti-aging products.
Isopropyl Palmitate (IPP) complies with TSCA and DSL.

Isopropyl Palmitate (IPP) is a fatty acid ester obtained by the formal condensation of carboxy group of palmitic acid with propan-2-ol.
Metabolite observed in cancer metabolism.
Isopropyl Palmitate (IPP) has a role as a human metabolite.
Isopropyl Palmitate (IPP) is a fatty acid ester and an isopropyl ester.
Isopropyl Palmitate (IPP) is functionally related to a hexadecanoic acid.
Isopropyl Palmitate (IPP) is primarily used in the pharmaceutical industry.
In pharmaceuticals, IPP acts as an emulsifier, solvent, humectant, and penetration enhancer in various formulations like creams, lotions, sprays, and gels.
Isopropyl Palmitate (IPP) helps improve the texture and absorption of topical medications.

Isopropyl Palmitate (IPP) Chemical Properties
Melting point: 11-13 °C (lit.)
Boiling point: 160°C 2mm
Density: 0.852 g/mL at 25 °C (lit.)
Vapor pressure: 0.007Pa at 25℃
Refractive index: n20/D 1.438(lit.)
Fp: >230 °F
Storage temp.: 2-8°C
Solubility: <0.001g/l
Form: <11°C Solid,>13°C Liquid
Color: Colourless
Odor: very sl. odor
Biological source: synthetic
Water Solubility: Not miscible or difficult to mix with water.
BRN: 1786567
InChIKey: XUGNVMKQXJXZCD-UHFFFAOYSA-N
LogP: 8.16
CAS DataBase Reference: 142-91-6(CAS DataBase Reference)
NIST Chemistry Reference: Isopropyl Palmitate (IPP)(142-91-6)
EPA Substance Registry System: Isopropyl Palmitate (IPP) (142-91-6)

Isopropyl Palmitate (IPP) is a clear, colorless to pale yellow-colored, practically odorless viscous liquid that solidifies at less than 16°C.

Uses
Isopropyl Palmitate (IPP) is an emollient and moisturizer, it also acts as a binder and solvent.
Similar to isopropyl myristate, Isopropyl Palmitate (IPP) is produced from the combination of palmitic acid (coconut or palm oil) and isopropyl alcohol.
Enzymes are able to metabolize Isopropyl Palmitate (IPP) and studies do not show allergic reactions or toxicity.
Some sources indicate comedogenicity potential.
Isopropyl Palmitate (IPP) is used to formulate and evaluate the suitability of pluronic lecithin organogels containing flurbiprofen for topical application and to characterize microemulsion systems of Isopropyl Palmitate (IPP), water and 2:1 Brij 97, and 1-butanol by different experimental techniques.
Isopropyl Palmitate (IPP) is a very effective ingredient and is used in a wide range of personal care and cosmetic products.
Isopropyl Palmitate (IPP) is beneficial for both skin and hair.

Skin care: Isopropyl Palmitate (IPP) is primarily an emollient that works to soften the skin and also soothe it.
Isopropyl Palmitate (IPP) improves the texture of the skin and reduces the appearance of fine lines and wrinkles.
Commonly, Isopropyl Palmitate (IPP) can be found in creams, lotions and moisturizers

Hair care: Isopropyl Palmitate (IPP) is often used in hair care products because it helps to improve the texture and manageability of hair.
Isopropyl Palmitate (IPP) can help to smooth the cuticle and reduce frizz, making hair more manageable and easier to style.
Isopropyl Palmitate (IPP) can also help to moisturize the hair and scalp, which can reduce itching and flakiness

Cosmetic products: Isopropyl Palmitate (IPP) is commonly used as a solvent.
Isopropyl Palmitate (IPP) can help to dissolve other ingredients and improve the consistency of the product.
Isopropyl Palmitate (IPP) can also help to enhance the spreadability of cosmetics, making them easier to apply to the skin.
Isopropyl Palmitate (IPP) is often used in foundations, lipsticks, and other makeup products

Pharmaceutical Applications
Isopropyl Palmitate (IPP) is a nongreasy emollient with good spreading characteristics, used in topical pharmaceutical formulations and cosmetics such as: bath oils; creams; lotions; make-up; hair care products; deodorants; lip products; suntan preparations; and pressed powders.
Isopropyl Palmitate (IPP) is an established penetration enhancer for transdermal systems.
Isopropyl Palmitate (IPP) has also been used in controlled-release percutaneous films.

Production Methods
Isopropyl Palmitate (IPP) is prepared by the reaction of palmitic acid with propan-2-ol in the presence of an acid catalyst.
A high-purity material is also commercially available, which is produced by enzymatic esterification at low temperatures.

Side effects
Side effects for the skin: If overused, Isopropyl Palmitate (IPP) may cause acne, blackheads, whiteheads, and clogged pores.
Depending on the content of the ingredients in the product, the skin may experience some irritation.
If Isopropyl Palmitate (IPP) is used without dilution, it may cause comedoles.
People with oily skin should also avoid isopropyl palmitate.

Side effects for hair: Excessive use of products containing Isopropyl Palmitate (IPP) on hair can make hair look untidy, oily, and untidy due to excessive moisture in the hair.
When there is an open wound on the scalp, Isopropyl Palmitate (IPP) should also be avoided.