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KATHON 886 MW is a registered tank side additive used to control bacteriological growth in metalworking fluids.
KATHON 886 MW microbicide is very effective against bacteria and fungi.
KATHON 886 MW is recommended for use in soluble, semi-synthetic, and synthetic metalworking fluids.
KATHON 886 MW is a formaldehyde-free, 14% active CMIT/MIT metalworking fluid microbicide for water-based cutting fluids.
KATHON 886 MW is used tankside and is recommended for use in soluble, semi-synthetic and synthetic metalworking fluids.
Soluble, synthetic, and semi-synthetic metalworking fluids or coolants provide an excellent environment for the growth of various microorganisms, including bacteria, mold, and yeast.
If allowed to grow, these organisms can have detrimental effects on the fluids.
For example, bacteria, which can grow very quickly, can destroy the integrity of the fluid by discoloration destroying lubricity characteristics, and causing emulsions to split.
Bacteria can also reduce the pH of the fluid, which can promote corrosion.
Some forms of bacteria have objectionable odors.
Fungi typically grow more slowly than bacteria, but can form large masses which clog filters and lines and in some cases lead to system shutdown; fungi also generate foul odors and can cause corrosion.
KATHON 886 MW microbicide is very effective against bacteria and fungi.
KATHON 886 MW is recommended for use in soluble, semi-synthetic, and synthetic metalworking fluids.
Due to the wide variations in coolant formulations, laboratory or pilot tests are recommended to evaluate KATHON 886 MW microbicide in specific metalworking fluids prior to commercial use.
KATHON 886 MW microbicide is supplied as a 14% active liquid in water.
KATHON 886 MW is registered with the U.S. EPA (Environmental Protection Agency), number 707-129.
KATHON 886 MW biocide utilizes a two-step mechanism involving rapid growth inhibition leading to a loss of cell viability.
Growth inhibition is the result of rapid disruption of the central metabolic pathways of the cell by inhibition of several specific enzymes, including dehydrogenases.
The critical enzymes which are affected are associated with the Krebs cycle (alpha- ketoglutarate, pyruvate, and succinate dehydrogenase), nutrient metabolism (lactate dehydrogenase) and energy generation (NADH dehydrogenase).
The key physiological activities that are rapidly inhibited in microbial cells are respiration (oxygen consumption), energy generation (ATP synthesis), and growth (assimilation).
Many of these key enzymes are present in both aerobic and anaerobic microorganisms, which explains why KATHON 886 MW is such a broad spectrum biocide.
Inhibition of cellular activity and growth is rapid (within minutes), whereas cell death (cidal activity) is observed after several hours contact. In general, the higher the concentration of biocide, the shorter the contact time required for more complete kill.
Cell death results from the progressive loss of protein thiols in the cell from one of multiple pathways.
As cell metabolism is disrupted, free radicals are produced which also results in cell death. This unique mechanism results in the broad spectrum of activity of KATHON 886 MW biocide, low use levels for microbial control, and difficulty in attaining resistance by mutation.
Within minutes after addition of KATHON 886 MW microbicide to a metalworking fluid sump, the metabolic activity of the microorganisms in the system shuts down.
This includes cellular respiration (oxygen uptake), growth, energy generation, and nutrient uptake.
The microorganisms, although still alive, are no longer able to reproduce or metabolize metalworking fluid components.
After 24 to 48 hours of contact with a lethal dose of the microbicide, most of the microorganisms have been killed.
KATHON 886 MW microbicide generally retains KATHON 886 MW antimicrobial efficacy in metalworking fluid systems for 1 to 4 weeks.
Variables such as degree of fluid contamination, effectiveness of the filtration system, system turnover time, compatibility between the microbicide and the metalworking fluid components, and other system additives involved, can affect the life of the microbicide in a system.
The active ingredients in KATHON 886 MW microbicide have been shown to reduce microbial fouling and prevent biofilm development.
A number of application studies have been conducted demonstrating reduction of both viable microorganisms (bacteria and fungi) as well as total biomass (total protein and dry solids) on industrial surfaces.
The benefits of reduced microbial fouling include improved system performance, reduced filter plugging, reduced biocorrosion, and improved microbial control.
Additional information on biofouling studies is presented in technical bulletin CS-673R.
The performance of KATHON 886 MW microbicide was tested in controlled laboratory studies versus a pure culture of Mycobacterium chelonae (ATCC 14472).
Results showed 7-20 ppm active ingredient prevented the growth of the Mycobacterium isolate (106 cfu/ml) in dilute and full strength nutrient broth.
An eradication study in a soluble oil fluid showed KATHON 886 MW microbicide at 9 ppm active ingredient was sufficient to provide complete kill of 103 bacteria/ml.
The term "bacterial endotoxin" is synonymous with the lipopolysaccharide (LPS) component of the outer membrane of Gram negative bacteria.
KATHON 886 MW is generally regarded that the Lipid A component of the LPS is directly responsible for the endotoxic activity of certain Gram negative bacteria.
The "endotoxin" terminology refers to the fact that the "toxin" is located on the exterior of the bacterial cell and is "released" from the cell into the surrounding liquid after cell death and lysis.
KATHON 886 MW is important to note that not all LPS from Gram negative bacteria are endotoxins.
The most heavily studied LPS are from Escherichia, Shigella and Salmonella, all of which are enteric or intestinal bacteria.
KATHON 886 MW microbicide has been shown to be efficacious versus many Gram negative bacteria, known to produce endotoxins, under controlled laboratory studies.
Minimum Inhibitory Concentrations for KATHON 886 MW microbicide are within the recommended use range for general bacterial control.
In addition, KATHON 886 MW microbicide does not function by cell lysis or membrane disruption, so killed cells would be less likely to release endotoxins.
KATHON 886 MW microbicide may encounter conditions in certain metalworking fluids where stability is reduced.
Several options exist to improve KATHON 886 MW’s performance and stability.
Addition of inorganic or organic forms of copper to the fluid may improve the stability of the active ingredients and reduce degradation.
Alternatively, KATHON MWC microbicide contains copper salts and is designed for aggressive conditions.
Addition of biosurfactants or biodispersants may improve KATHON 886 MW’s efficacy, especially against biofilms or heavily contaminated systems.
Addition of a chelant, such as EDTA, may also boost efficacy in challenging systems.
KATHON 886 MW microbicide was evaluated for efficacy against thermophilic bacteria in 4 hot aluminum rolling oils.
KATHON 886 MW microbicide at 20 ppm a.i. (143 ppm as supplied) controlled microbial growth at 54°C in all 4 of the fluids (at recommended dilutions) at least 4 weeks and in 1 fluid for 3 weeks.
Tankside Biocide:
KATHON biocides have been used safely and effectively in a variety of industries around the world for more than 20 years. In 1977 Rohm and Haas Company was granted EPA registration for KATHON 886 MW microbicide for use in metalworking fluids, in 2 piece can manufacture, hot aluminum rolling, and general machinery of ferrous and aluminum materials. In 1986, this registration was expanded to include the use of KATHON 886 MW microbicide in metal cleaners and water-based hydraulic fluids.
The information in this brochure has been compiled to familiarize users of KATHON 886 MW microbicide with KATHON 886 MW chemistry, to communicate the tremendous benefits of this product as well as the potential hazards, to provide directions for safe and efficient use of the product, and to aid the user in the event of misuse.
Particular attention should be paid to the Compatibility section of this brochure which provides insight on the stability of KATHON 886 MW microbicide with individual components and additives frequently used in metalworking fluid operations.
KATHON 886 MW microbicide can be used safely and effectively by following the instructions and precautions outlined in this brochure, on the product label, and on the Rohm and Haas Material Safety Data Sheet.
Key Features and Benefits of KATHON 886 MW:
Features of KATHON 886 MW:
Highly effective microbicide,
Broad spectrum activity,
Efficacious versus specific problem-causing microorganisms,
Effective against,
Good temperature and pH stability,
Highly soluble in water and does not foam,
Provides long lasting microbial control,
Fast acting,
Effective at low use rates (10 to 17 ppm ai) and biodegradable,
Does not contain or release formaldehyde.
Benefits of KATHON 886 MW:
Extends metalworking fluid life, resulting in reduced makeup fluid use and costs and lower waste fluid disposal costs.
Provides long lasting and effective contamination prevention versus bacteria and fungi (no performance gaps).
Mycobacterium and endotoxin-producing bacteria (based on controlled laboratory studies).
Works well in a variety of metalworking conditions up to 60°C (140°F) and pH 9.2.
Cost effective versus competitive tankside treatments.
Quickly controls microbial activity (oxygen consumption) and odor-causing bacteria and fungi.
Better for the environment.
Not subject to formaldehyde concerns.
Directions For Use of KATHON 886 MW:
Metalworking Fluid Preservation:
For maintenance of a non-fouled system, use KATHON 886 MW microbicide at 2.7 fluid ounces (0.23 pounds) per 1,000 gallons of emulsion every 4 weeks or 2.7-12.8 fluid ounces (0.23-1.1 pounds) per 1,000 gallons of emulsion every 8-12 weeks.
For a noticeable fouled system use an initial dose of 5.4-12.8 fl oz (0.46-1.1 pounds) per 1,000 gallons of emulsion followed by subsequent maintenance dosages depending upon the treatment interval noted above.
A higher dosage range and/or increased frequency of treatment may be required depending upon rate of dilution of the preservative with makeup fluid, the nature and severity of contamination, level of control required, filtration effectiveness, and system design, etc.
The preservative should be dispensed into the use dilution of the metalworking fluid using a metering pump and uniformly dispersed throughout the system.
Metal Cleaning Fluid Preservation:
KATHON 886 MW microbicide is recommended as a preservative for the manufacture and use of alkaline, acid, and emulsion based metal cleaning fluids typically used in electroplating, phosphatizing, galvanizing, and general metal cleaning operations.
For addition to a metal cleaning concentrate add KATHON 886 MW at a level to ensure that the final use-dilution fluid contains 44 to 147 ppm as supplied (6.25 - 25 ppm active isothiazolones).
When direct addition to a fouled system, add 5.6-22.6 fl oz (0.48-1.9 lbs) of microbicide to each 1,000 gallons of use-diluted metal cleaning fluid every 3 to 4 weeks to provide 44 to 177 ppm as supplied (6.25 to 25 ppm active isothiazolones).
A higher dosage range and/or increased frequency may be required depending upon dilution rate of the preservative with makeup fluid, the nature and severity of contamination, level of control required, filtration effectiveness, and system design, etc.
The preservative should be dispensed into the use-dilution metal cleaning fluid using a metering pump and uniformly dispersed throughout the system.
Water Based Hydraulic Fluid Preservation:
KATHON 886 MW microbicide is recommended as a preservative for use in the manufacture and use of high waterbased hydraulic fluids and invert emulsion hydraulic fluids.
For the maintenance of a nonfouled system, use KATHON 886 MW microbicide at 9-13 fluid oz (0.76-1.1 lbs) per
1,000 gallons of fluid every 8 weeks. For a noticeably fouled system use an initial dose of 13 to 20 fluid ounces (1.1-1.7 lbs) per 1,000 gallons fluid followed by subsequent maintenance doses.
A higher dosage range and/or increased frequency of treatment may be required depending upon rate of dilution of the preservative with makeup fluid, the nature and severity of contamination, level of control required, filtration effectiveness, system design, etc.
The preservative should be dispensed into the use-dilution of the hydraulic fluid using a metering pump and uniformly dispersed throughout the system.
Recommended Use Practices of KATHON 886 MW:
General Practices When Using KATHON Biocides:
Know the size of your system and dose at the recommended use levels.
To improve performance and longevity add KATHON 886 MW microbicide on the clean side of the filters.
KATHON 886 MW may be necessary to occasionally add KATHON 886 MW microbicide to the dirty side of the filters if large populations of microorganisms are detected there.
Minimize contamination:
Eliminate or minimize dead spots,
Disconnect unused portions of the system,
Do not throw trash in sumps.
Always remember to triple rinse (or equivalent) empty KATHON 886 MW containers to avoid incidental contact.
Post placard with safety information and deactivation protocol near biocide handling area.
Maximizing the Performance of KATHON 886 MW Fungicide Additional guidelines for maximizing the performance of KATHON 886 MW microbicide are as follows:
KATHON 886 MW microbicide stability and performance is improved with lower pH. Whenever possible maintain the pH of system below pH 9.2. Lower pH also makes amines and amine-containing compounds less aggressive.
For systems with pH greater than 9.5, we strongly recommend determination of biological efficacy and chemical stability prior to use.
Avoid adding highly basic additives (alkaline materials with pH of 10-12) immediately prior to or after adding KATHON 886 MW microbicide to your system. If a highly basic additive must be added, allow sufficient time (at least 30 minutes) between additions.
Minimize levels of diethanolamine (DEA) in your system.
If possible use 99% triethanolamine (TEA) or monoethanolamine (MEA) instead of DEA, and use these at as low a level as possible.
Avoid use of mercaptans such as mercaptobenzothiazole.
Some biocides are incompatible with KATHON 886 MW and can degrade KATHON 886 MW.
To maintain performance avoid using Sodium Omadine and Triadine 10 with KATHON 886 MW microbicide.
If a fungicide is needed, use KATHON 893 MW fungicide.
KATHON 886 MW is completely compatible with KATHON 886 MW microbicide.
Always add KATHON 886 MW microbicide directly to the metalworking fluid sump.
Never use KATHON 886 MW microbicide in a spray bottle.
Avoid charging KATHON 886 MW microbicide in high temperature zones, since increasing temperatures accelerate other degradation effects.
Ideally, add KATHON 886 MW microbicide to the fluid below 60°C (140°F).
Avoid adding KATHON 886 MW microbicide and incompatible corrosion inhibitors directly to the tank at the same time.
Solubility of KATHON 886 MW:
KATHON 886 MW microbicide is soluble in water, methanol, ethanol, isopropyl alcohol, acetic acid, and 3.5 parts nbutanol.
KATHON 886 MW microbicide is insoluble in acetone.
Stability pH - KATHON 886 MW microbicide is stable over a wide pH range (3.0-9.2) in water and metalworking fluid systems.
KATHON 886 MW stability and performance are improved at lower pH.
Whenever possible the pH of a system should be maintained below pH 9.2.
Storage of KATHON 886 MW:
KATHON 886 MW microbicide is stable as supplied for at least one year at ambient temperatures and at least six months at 50°C.
Typical Physical Properties of KATHON 886 MW:
These properties are typical but do not constitute specifications.
Appearance: Amber to gold, slightly viscous liquid
Odor: Mild, aromatic
Specific Gravity: 25°C - 1.29
Density: lb./gal. 10.8
pH: 1 to 3
Viscosity: cps 25°C - 16°C
Melting Point: –33°C
Boiling Point: 100°C
Vapor Pressure: (mm Hg) 23°C - 0.1
Synonyms of KATHON 886 MW:
Kathon 886
55965-84-9
Kathon biocide
Kathon CG
Kathon LX
Zonen F
ProClin 300
2-Methylisothiazol-3(2H)-one compound with 5-chloro-2-methylisothiazol-3(2H)-one(14%in H2O)
UNII-15O9QS218W
15O9QS218W
5-chloro-2-methyl-1,2-thiazol-3-one;2-methyl-1,2-thiazol-3-one
Bio-Perge
Kathon WT
3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with 2-methyl-3(2H)-isothiazolone
Microcide III
Somacide RS
5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazolone
Legend MK
Kathon 886MW
Kathon CG/ICP II
Slaoff 360
Kathon 886 W
Kathon RH 886
MBC 215
Tret-O-Lite XC 215
3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with2-methyl-3(2H)-isothiazoloneOTHER CA INDEX NAMES:3(2H)-Isothiazolone, 2-methyl-, mixt. contg.
CCRIS 4652
KKM 43
EPA Pesticide Chemical Code 107103
2-Methylisothiazol-3(2H)-one 5-chloro-2-methylisothiazol-3(2H)-one (1:1)
C8H9ClN2O2S2
SCHEMBL348332
CHEMBL108095
KS-00000R9C
8175AB
MFCD01716911
AKOS016842708
CS-W018768
2-Methylisothiazol-3(2H)-one compound with 5-chloro-2-methylisothiazol-3(2H)-one (1:1)
AK128362
CS-17384
965K849
Q26841195
2-Methylisothiazol-3(2H)-one 5-chloro-2-Methylisothiazol-3(2H)-one
2-Methylisothiazol-3(2H)-one 5-chloro-2-methylisothiazol-3(2H)-one (1:1) 14% in water
2-Methylisothiazol-3(2H)-one compound with 5-chloro-2-methylisothiazol-3(2H)-one (14% in H2O)
