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Kollidon VA 64 Fine is a water-soluble copolymer composed of vinylpyrrolidone (VP) and vinyl acetate (VA) in a 6:4 ratio.
Kollidon VA 64 Fine is widely used in pharmaceutical, cosmetic, and industrial applications as a binder, film-former, and solubilizer.
Kollidon VA 64 Fine is a white to slightly yellowish, fine powder with good adhesive and film-forming properties, making it particularly useful in tablet formulations and as a dry binder in direct compression processes.
CAS Number: 25086-89-9
Synonyms:
VP/VA Copolymer,Polyvinylpyrrolidone-vinyl acetate copolymer,PVP-VA Copolymer,Copovidone
Introduction
Kollidon VA 64 Fine is a versatile excipient primarily used in the pharmaceutical, food, and cosmetic industries.
It is a polyvinylpyrrolidone (PVP) derivative with specific molecular properties that allow it to function as a binder, stabilizer, and solubilizer.
It is commonly used in tablet formulations, including those that are designed for oral drug delivery.
The fine form of Kollidon VA 64 exhibits distinct advantages in formulations requiring enhanced flowability and solubility.
This section provides an overview of Kollidon VA 64 Fine, its origin, and its significance in various applications.
Chemical Composition and Molecular Structure
Kollidon VA 64 Fine is made from polyvinylpyrrolidone (PVP), a polymer that contains the repeating unit of N-vinylpyrrolidone.
The molecular formula for PVP is
(
