Quick Search
L-Leucine is an essential branched-chain amino acid (BCAA) critical for protein synthesis, muscle recovery, and energy production.
It cannot be synthesized by the body and must be obtained through dietary sources or supplementation.
L-Leucine is widely used in sports nutrition, pharmaceuticals, and food formulations for its anabolic and metabolic roles.
CAS Number: 61-90-5
EC Number: 200-522-0
Molecular Formula: C6H13NO2
Molecular Weight: 131.17 g/mol
Synonyms: L-Leucine, 2-Amino-4-methylpentanoic Acid, (S)-2-Amino-4-methylpentanoic Acid, Leucine, BCAA L-Leucine, Essential Amino Acid Leucine, Muscle Recovery Amino Acid, L-Leucine Powder, Pharmaceutical Grade L-Leucine, Sports Nutrition Leucine, Protein Synthesis Amino Acid, L-Leucine for Supplements, Leucine for Metabolic Support, Leucine for Muscle Growth, Food Grade L-Leucine
APPLICATIONS
L-Leucine is widely used in dietary supplements, such as BCAA powders and capsules, to promote muscle growth and recovery.
L-Leucine is included in sports nutrition products, including protein shakes and bars, to enhance athletic performance and reduce fatigue.
L-Leucine is employed in medical nutrition for patients requiring muscle preservation, such as those with chronic illnesses or during recovery.
L-Leucine is incorporated into food and beverage formulations, including fortified foods, to support protein metabolism.
L-Leucine is used in pharmaceutical formulations for its role in promoting wound healing and tissue repair.
L-Leucine is applied in intravenous nutrition to provide essential amino acids for critically ill patients.
L-Leucine is found in animal feed formulations to enhance protein utilization and promote growth in livestock.
L-Leucine is used in laboratory research to study protein synthesis and metabolism.
L-Leucine is included in weight management products to support muscle retention during calorie-restricted diets.
L-Leucine is utilized in formulations targeting sarcopenia and age-related muscle loss to support muscle mass maintenance.
L-Leucine is employed in specialized medical foods for conditions requiring high protein intake.
L-Leucine is used in skincare formulations for its potential to support collagen synthesis and skin repair.
L-Leucine is added to functional beverages and snacks aimed at fitness enthusiasts and athletes.
L-Leucine is applied in plant-based protein supplements to enhance the amino acid profile.
L-Leucine is used in formulations to prevent muscle catabolism in individuals on low-protein diets.
L-Leucine is widely used in sports nutrition supplements for its ability to promote muscle protein synthesis and support muscle recovery after exercise.
L-Leucine is employed in bodybuilding supplements to enhance strength, improve endurance, and promote muscle growth.
L-Leucine is used in clinical nutrition to aid in the recovery of patients with muscle wasting conditions, such as those suffering from cancer, burns, or severe injuries.
L-Leucine is included in protein powders to improve the bioavailability and effectiveness of protein supplementation, supporting muscle repair and growth.
L-Leucine is used in pre-workout supplements to boost energy levels and enhance workout performance by increasing endurance and reducing muscle fatigue.
L-Leucine is incorporated into weight loss supplements for its role in preserving lean muscle mass while promoting fat loss.
L-Leucine is applied in pediatric nutrition to support the healthy growth and development of infants and children, particularly in individuals with protein malnutrition.
L-Leucine is used in enteral feeding formulas to support recovery in patients who are unable to consume food orally.
L-Leucine is included in anti-aging supplements to help preserve muscle mass and improve overall body composition in older adults.
L-Leucine is employed in dairy products, such as protein-rich beverages and nutritional bars, to enhance the protein content and support muscle maintenance.
L-Leucine is used in food fortification, especially for individuals with special dietary needs or muscle-related health concerns, to improve overall nutritional intake.
L-Leucine is incorporated in energy drinks for its potential to provide sustained energy and support optimal physical performance.
L-Leucine is used in veterinary medicine to improve muscle health and recovery in animals after surgery or illness.
L-Leucine is applied in cosmetic formulations, particularly in anti-aging products, to support collagen production and skin elasticity.
L-Leucine is employed in the formulation of amino acid injections or IV fluids, aiding in the recovery of patients in critical care or undergoing long-term treatments.
L-Leucine is used in muscle-building supplements for athletes to enhance muscle mass and strength while minimizing muscle breakdown during intense training.
L-Leucine is used in protein supplements aimed at improving the performance of endurance athletes, helping them maintain muscle mass and avoid catabolism during long workouts.
L-Leucine is included in high-protein meal replacement shakes and bars to provide a convenient source of amino acids for those with active lifestyles or dietary restrictions.
L-Leucine is used in post-workout recovery formulas to help reduce muscle soreness and promote faster recovery after intense physical activity.
L-Leucine is included in supplements for metabolic disorders to help regulate blood sugar levels and support overall metabolic function.
L-Leucine is employed in weight management programs to help prevent the loss of lean muscle mass during calorie restriction.
L-Leucine is used in sports drinks and recovery drinks to help restore energy, build muscle, and support metabolic function post-exercise.
L-Leucine is included in protein-based nutritional shakes for older adults to support healthy aging, prevent muscle loss, and maintain bone health.
L-Leucine is used in clinical dietetic formulations designed for individuals recovering from surgery or trauma to promote muscle rebuilding and recovery.
L-Leucine is incorporated into energy-boosting snacks for athletes to sustain energy levels and enhance physical performance during endurance activities.
DESCRIPTION
L-Leucine is a white crystalline powder with a slightly bitter taste and no discernible odor.
This amino acid is hydrophobic, making it highly effective in the structural stability of proteins.
L-Leucine is essential for activating the mTOR pathway, which plays a key role in protein synthesis and muscle growth.
L-Leucine is found naturally in high-protein foods, such as meat, dairy, legumes, and nuts.
This amino acid is rapidly absorbed and metabolized, making it ideal for pre- and post-workout supplementation.
L-Leucine enhances energy production by serving as a precursor for the synthesis of alanine and glutamine during exercise.
L-Leucine contributes to nitrogen balance and prevents muscle breakdown under stress or caloric deficits.
This compound is stable under normal storage conditions, ensuring its effectiveness in dietary and pharmaceutical products.
L-Leucine supports overall metabolic health by improving glucose regulation and insulin sensitivity.
L-Leucine is an essential branched-chain amino acid (BCAA) that plays a crucial role in protein synthesis and muscle metabolism.
L-Leucine is one of the nine essential amino acids, meaning it cannot be synthesized by the body and must be obtained through diet or supplementation.
L-Leucine is primarily found in high-protein foods such as meat, dairy, eggs, and legumes, and is often included in amino acid supplements for muscle health.
L-Leucine is essential for regulating blood sugar levels, enhancing muscle recovery, and promoting the synthesis of muscle proteins following physical activity.
L-Leucine is known to activate the mTOR (mechanistic target of rapamycin) pathway, which plays a key role in muscle growth, cell regeneration, and repair.
L-Leucine is important in maintaining a positive nitrogen balance in the body, which is critical for muscle growth and recovery during and after exercise.
L-Leucine is considered a potent anabolic amino acid, promoting muscle building while helping to prevent muscle catabolism (breakdown).
L-Leucine has been shown to improve endurance by decreasing fatigue and supporting the energy needs of muscles during prolonged exercise.
L-Leucine is frequently used in combination with other BCAAs, such as isoleucine and valine, for optimal muscle repair, growth, and maintenance.
L-Leucine is naturally present in the body in various tissues, including muscle cells, where it plays a significant role in protein metabolism and muscle function.
PROPERTIES
Chemical Formula: C6H13NO2
Molecular Weight: 131.17 g/mol
Common Name: L-Leucine
Appearance: White crystalline powder
Odor: Odorless
Taste: Slightly bitter
Solubility: Soluble in water; slightly soluble in ethanol
Melting Point: Approx. 293°C (decomposes)
Reactivity: Stable under normal conditions; avoid strong oxidizing agents
Chemical Stability: Stable in a wide pH range
Storage Temperature: Store at 15–30°C in a cool, dry place
FIRST AID
Inhalation:
If L-Leucine dust is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.
Skin Contact:
Wash the affected area thoroughly with soap and water.
If skin irritation or rash develops, seek medical attention.
Remove contaminated clothing and wash before reuse.
Eye Contact:
Flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.
Ingestion:
If L-Leucine is ingested in large amounts, rinse the mouth thoroughly with water.
Seek medical attention if discomfort or symptoms persist.
If the person is conscious, give small sips of water to drink.
Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care as needed.
HANDLING AND STORAGE
Handling:
Personal Protection:
Wear appropriate personal protective equipment (PPE), such as gloves, safety goggles, and protective clothing, when handling L-Leucine.
Avoid generating dust during handling.
Ventilation:
Ensure proper ventilation to minimize exposure to airborne particles.
Use local exhaust systems if necessary.
Avoidance:
Avoid direct contact with eyes, skin, and clothing.
Do not eat, drink, or smoke while handling.
Wash hands thoroughly after handling.
Spill and Leak Procedures:
Contain spills to prevent further release.
Use inert absorbent materials (e.g., sand, vermiculite) to collect spilled material.
Dispose of waste according to local regulations.
Storage:
Store in a cool, dry, well-ventilated area away from moisture, heat, and incompatible materials.
Keep containers tightly closed and properly labeled.
Protect from direct sunlight and contamination.
Handling Cautions:
Avoid prolonged exposure to high humidity or temperatures to maintain product integrity.
Ensure containers are sealed properly to prevent contamination.
