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Lake Quinoline Yellow is used in personal care and cosmetics.
Lake Quinoline Yellow is a water-insoluble pigment made by precipitating Quinoline Yellow dye onto an inert substrate—typically aluminum hydroxide—which converts the originally water-soluble dye into a form that can be used in oil-based or non-aqueous applications.
Lake Quinoline Yellow is a coloring pigment.
CAS Number: 12225-21-7
Molecular Formula: C16H9N4O9S2.3Na
Molecular Weight: 534.368
EINECS Number: 235-428-9
Synonyms: 94803-32-4, 2-(1,3-dioxo-2,3-dihydro-1h-inden-2-yl)quinoline-6,8-disulfonic acid, G5MIQ8Q13H, UNII-G5MIQ8Q13H, 6,8-Quinolinedisulfonic acid, 2-(2,3-dihydro-1,3-dioxo-1H-inden-2-yl)-, DTXSID10873126, Chinogelb, Chinogelb Extra, 6,8-Quinolinedisulfonic acid, 2-(1,3-dioxo-2-indanyl)-, Quinoline Yellow S, Jaune de quinoleine, Food Yellow 13, Quinidine Yellow KT, Dye Quinoline Yellow, Japan Yellow 203, Lemon Yellow ZN 3, Basacid Yellow 094, Schultz No. 918, Quinoline Yellow Extra, L-Gelb 3, D&C Yellow No. 10, D and C Yellow No. 10, D & C Yellow no. 10, FD and C Yellow No. 10, Vitasyn Quinoline Yellow 70, CI 47005, 2-(2-Quinolyl)-1,3-indandione disulfonic acid disodium salt, Yellow 203 Aluminum Lake, C.I. Acid yellow 3, 9CI, SCHEMBL5356629, CHEMBL3306382, DTXCID7027964, PD094565, NS00019538, Food Yellow 4:1;KI4;C.I. Pigment Yellow 100;Acid yellow 23 aluminum lake (C.I. 19140:1);Pigment yellow 100 (C.I. 19140:1);Tartrazine alaminium lake;C.I. 19140:1;1H-Pyrazole-3-carboxylic acid, 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-((4-sulfophenyl)azo)- aluminum salt
Lake Quinoline Yellow is a mixture of organic compounds derived from the dye Quinoline Yellow SS (spirit soluble).
Owing to the presence of sulfonate groups, the WS dyes are water-soluble (WS).
Lake Quinoline Yellow is a mixture of disulfonates (principally), monosulfonates and trisulfonates of 2-(2-quinolyl)indan-1,3-dione with a maximum absorption wavelength of 416 nm. p. 119
Lake Quinoline Yellow gives coloration through Dispersion for coloration this product, first pre-disperse in any suitable medium (like propylene glycol, glycerol any convenient medium which is compatible to final product).
This dispersion is then used for the coloration of final product.
Lake Quinoline Yellow can be used in cosmetic products.
It is a yellow color organic pigment.
Lake Quinoline Yellow is an EEC lake based color.
This process, known as “laking”, creates a stable, colored compound that maintains the hue of the original dye while becoming suitable for use in products that require color stability in fats, oils, waxes, and certain plastics.
Unlike the basic dye version, which dissolves easily in water and is used in beverages, gels, and some medications, Lake Quinoline Yellow is dispersible but not soluble, meaning it can be blended into formulations without dissolving, helping to provide consistent and uniform coloring in solid or semi-solid products.
Lake Quinoline Yellow has not been associated with any significant long-term toxicity, is not genotoxic or carcinogenic and there is no evidence of adverse effects on reproduction or development.
Lake Quinoline Yellow colorants in general have been the subject of much scrutiny for their effect on health.
Since the 1970s and the well-publicized advocacy of Benjamin Feingold, there has been public concern that food colorings may cause ADHD-like behavior in children.
These concerns have led the U.S. FDA and other food safety authorities to regularly review the scientific literature, and led the UK FSA to commission a study by researchers at the University of Southampton to assess the effect of a mixture of six food dyes (Tartrazine, Allura Red, Ponceau 4R, Quinoline Yellow WS, Sunset Yellow FCF and Carmoisine (dubbed the "Southampton 6")) and sodium benzoate (a preservative) on children in the general population, who consumed them in beverages; the study published in 2007.
The study found "a possible link between the consumption of these artificial colours and a sodium benzoate preservative and increased hyperactivity" in the children; the advisory committee to the FSA that evaluated the study also determined that because of study limitations, the results could not be extrapolated to the general population, and further testing was recommended".
The European regulatory community, with a stronger emphasis on the precautionary principle, required labelling and temporarily reduced the acceptable daily intake (ADI) for the food colorings; the UK FSA called for voluntary withdrawal of the colorings by food manufacturers.
However, in 2009 the EFSA re-evaluated the data at hand and determined that "the available scientific evidence does not substantiate a link between the color additives and behavioral effects".
On the basis of other evidence the EFSA also reduced the acceptable daily intake (ADI) from 10 to 0.5 mg/kg.
The US FDA did not make changes following the publication of the Southampton study, but following a citizen petition filed by the Center for Science in the Public Interest in 2008, requesting the FDA ban several food additives, the FDA commenced a review of the available evidence, and still made no changes.
No evidence supports broad claims that food coloring causes food intolerance and ADHD-like behavior in children.
Lake Quinoline Yellow is possible that certain food coloring may act as a trigger in those who are genetically predisposed, but the evidence is weak.
Lake Quinoline Yellow occurs a yellow powder or granules and is manufactured by sulfonating 2-(2-quinolyl)-1,3-indandione.
Lake Quinoline Yellow can be converted to a corresponding aluminum lake.
Lake Quinoline Yellow is commonly used in cosmetics (like eyeshadows, lipsticks, and nail polishes), pharmaceutical tablets and capsules, and food coatings, especially where a strong yellow shade is needed and water solubility is not desirable.
It offers good light stability, tinting strength, and resistance to bleeding or migration, making it a preferred pigment in products that need long-lasting, vibrant color.
From a regulatory perspective, Lake Quinoline Yellow is approved in some regions (such as the EU and parts of Asia) for specific uses, while in others, like the United States, Quinoline Yellow and its lake form are not approved for use in food, drugs, or cosmetics.
Manufacturers must always check local regulations to determine whether its use is permitted and under what conditions.
Lake Quinoline Yellow is the pigment form of the Quinoline Yellow dye, offering enhanced versatility for a wide range of non-aqueous product applications while retaining its bright lemon-yellow appearance.
Lake Quinoline Yellow belongs to the class of quinophthalone dyes.
Lake Quinoline Yellow is generally used as a food colorant.
Lake Quinoline Yellowis anionic in nature and is used to dye wool and silk.
Studies show that Lake Quinoline Yellow is not genotoxic or carcinogenic.
Lake Quinoline Yellow is considered to be safe for human health.
Density: 0.341[at 20℃]
solubility: 600mg/L in organic solvents at 20 ℃
pka: 0[at 20 ℃]
Odor: Odorless
Water Solubility: 561.286mg/L at 30℃
LogP: 0.028 at 25℃
Lake Quinoline Yellow is an organonitrogen compound and an organooxygen compound.
Lake Quinoline Yellow is functionally related to an alpha-amino acid.
Lake Quinoline Yellow is an azo dye complex azo, diazo, azido compounds can detonate.
This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids.
Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents.
Flammable gases are formed by mixing materials in this group with alkali metals.
Lake Quinoline Yellow explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides.
Lake Quinoline Yellow is acid yellow 3 aluminum lake colorant. The product is used in solid sticks and soaps.
Lake Quinoline Yellow is a food color lake pigment formed by precipitation of a food synthetic dye on an insoluble substrate (aluminum hydroxide) in form of aluminum salt that is 12-14% dye and 18-22% dye.
This product can be used as a direct food colorant in bakery products, dairy products, seasonings, and beverages.
Lake Quinoline Yellow is a quinoline derivative with a 1,3-dioxoindan-2-yl substituent at C-2.
Lake Quinoline Yellow has a role as a dye. Quinoline yellow is a member of quinolines, a beta-diketone and an aromatic ketone.
Lake Quinoline Yellow is used in cosmetic composition for application to the skin, lips, and/or body surface.
Lake Quinoline Yellow is a bright yellow dye with green shade.
Lake Quinoline Yellow is insoluble in water, but soluble in nonpolar organic solvents.
Lake Quinoline Yellow is representative of a large class of quinophthalone pigments.
Lake Quinoline Yellow is suggested that Lake Quinoline Yellow exhibits excited-state intramolecular proton transfer (ESIPT) behavior and the behavior might be the cause of its decent photostability, by recent spectroscopic study
Lake Quinoline Yellow occurs a yellow powder or granules and is manufactured by sulfonating 2-(2-quinolyl)-1,3-indandione. Quinoline yellow can be converted to a corresponding aluminum lake.
Lake Quinoline Yellow is formed by reacting the Quinoline Yellow dye—a synthetic sulfonated dye from the quinophthalone group—with a metallic salt, typically aluminum hydroxide, to produce a lake pigment.
This process removes the dye’s water solubility and makes it insoluble but dispersible, creating a fine powder pigment.
The term "lake" refers to this class of pigments, which are created by combining soluble dyes with an insoluble base to produce a stable, colored compound.
The laking process retains the dye’s original color, giving the pigment a vivid yellow hue, often described as lemon yellow or greenish-yellow, but transforms it chemically so it behaves differently in formulations.
Lake Quinoline Yellow is often listed as Quinoline Yellow Lake, CI Pigment Yellow 47, or CI 47005:1 in ingredient declarations.
Because it does not dissolve in water, Lake Quinoline Yellow remains stable in oil-based products or dry formulations.
This helps prevent migration, leaching, or smearing of color, making it ideal for long-wearing products.
The lake form provides uniform color dispersion, especially in pressed powders, ointments, and solid dosage forms like tablets or capsules.
Lake Quinoline Yellow ensures the final product has an even, smooth appearance without streaks or spotting.
Lake pigments are generally more resistant to light, heat, and oxidation than dyes.
Lake Quinoline Yellow resists color fading over time, making it suitable for products that may be exposed to light or stored for long periods.
Unlike soluble dyes, which may appear more translucent, Lake Quinoline Yellow offers greater opacity, which helps mask underlying material colors and improves visual appeal in coatings and cosmetics.
Used in eye makeup, blushes, lipsticks, face powders, nail polish, and lotions, Lake Quinoline Yellow helps provide a bright yellow or greenish-yellow tint that blends well with other pigments.
Lake Quinoline Yellow’s especially valued for its non-bleeding properties in oil-based and wax-based formulations.
In coated tablets, gelatin capsules, and chewable medications, Lake Quinoline Yellow serves as a colorant that remains stable and evenly distributed during manufacturing and storage.
It is often used to enhance brand identity or signal flavor or dosage.
In regions where it is permitted, such as the European Union, India, and Japan, it may be used in food coatings, decorations, or certain confections.
However, Lake Quinoline Yellow's important to note that Quinoline Yellow and its lake form are not permitted for use in food or cosmetics in the United States due to FDA restrictions.
Outside regulated industries, it may be used in stationery, inks, plastics, paints, or craft materials to achieve strong yellow coloring with good stability in diverse formulations.
In the EU, Lake Quinoline Yellow is assigned E104, and its lake form is often used under the same classification, subject to maximum permitted levels depending on the product type.
Lake Quinoline Yellow has been linked in some studies to hyperactivity in children, especially when combined with other food colorants and preservatives.
Due to this, products containing it in the EU may require warning labels.
Approved in regions like the EU, Australia, and Japan, but banned in the U.S. for ingestion or topical use.
Lake Quinoline Yellow is always essential to verify local regulatory status before use.
Uses Of Lake Quinoline Yellow:
Lake Quinoline Yellow is a synthetic organic pigment dyes and metabolites, Environmental Testing.
Lake Quinoline Yellow is used as a greenish yellow food additive in certain countries, designated in Europe as the E number E104.
In the EU and Australia, Quinoline Yellow is permitted in beverages and is used in foods, like sauces, decorations, and coatings; Lake Quinoline Yellow is not listed as a permitted food additive in Canada or the US, where it is permitted in medicines and cosmetics and is known as D&C Yellow 10.
Lake Quinoline Yellow is used in spirit lacquers, polystyrene, polycarbonates, polyamides, acrylic resins, and to color hydrocarbon solvents.
Lake Quinoline Yellow is also used in externally applied drugs and cosmetics.
Lake Quinoline Yellow is used in some yellow colored smoke formulations.
Lake Quinoline Yellow belongs to the class of quinophthalone dyes.
Lake Quinoline Yellow is generally used as a food colorant. Quinoline Yellow is anionic in nature and is used to dye wool and silk.
Studies show that Lake Quinoline Yellow is not genotoxic or carcinogenic.
Lake Quinoline Yellow is considered to be safe for human health.
Lake Quinoline Yellow is used in the following products: cosmetics and personal care products.
Other release to the environment of Quinoline Yellow is likely to occur from: indoor use as processing aid.
Release to the environment of Lake Quinoline Yellow can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.
Other release to the environment of Lake Quinoline Yellow is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. ooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Lake Quinoline Yellow can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones).
Lake Quinoline Yellow can be used to color cosmetics, drugs, and food, including dietary supplements, sauces, soups and broths, bakery, dairy fats and oil, seafood, seasonings, breath fresheners, desserts, and convenient foods, and beverages.
Lake Quinoline Yellow is widely used as a coloring agent in cosmetic products, particularly in lipsticks, blushes, eyeshadows, foundations, face powders, nail polishes, and eyeliners.
Because it is oil-dispersible and not water-soluble, it is especially effective in waxy or oily formulations, where it provides vibrant, long-lasting color without bleeding or smearing.
Its bright yellow to yellow-green hue makes it ideal for blending with other pigments to create a wide range of tones and shades.
This lake pigment is frequently used in the pharmaceutical industry to impart color to coated tablets, gelatin capsules, chewable tablets, and oral suspensions.
The color serves both functional and branding purposes, helping to distinguish between different drugs or dosages, enhance the product’s appearance, and improve patient compliance by making medication more visually appealing.
The pigment’s stability also ensures that the color remains consistent throughout the shelf life of the product.
Lake Quinoline Yellow can be found in various personal care products, including soaps, lotions, bath bombs, and creams, where it provides a decorative and aesthetically pleasing appearance.
Its resistance to water solubility makes it especially suited for products that are exposed to moisture during use but still need to retain a rich, even color.
In some countries—such as those in the European Union, India, and parts of Asia—Lake Lake Quinoline Yellow is approved for use in food applications.
Lake Quinoline Yellow is commonly used in candy coatings, cake decorations, chewing gum, and colored tablet coatings to produce an attractive yellow appearance that does not dissolve easily in saliva or moisture.
Because of its non-soluble nature, it provides a glossy, uniform finish to food surfaces without bleeding into other parts of the product.
Outside of regulated industries, Lake Quinoline Yellow is often incorporated into printing inks, markers, colored plastics, craft paints, and modeling compounds.
Its excellent color fastness, light stability, and resistance to heat and chemical changes make it an ideal pigment for materials that need to maintain color integrity over time.
Lake Quinoline Yellow is especially useful in school supplies and hobby materials where bright, bold colors are desirable.
In multi-product companies, Lake Quinoline Yellow is often used for visual identification—helping differentiate flavors, formulations, or strengths of a product line.
For example, a yellow-tinted tablet or cosmetic product can instantly signal a lemon flavor, a particular vitamin, or a mild variant.
Because the pigment stays on the surface and retains its hue well, it plays a key role in product consistency and customer recognition.
Safety Profile Of Lake Quinoline Yellow:
Lake Quinoline Yellow, like many synthetic colorants, has been known to cause allergic reactions in certain individuals, especially those with sensitivities to artificial dyes.
Skin irritation, itchiness, or even dermatitis may occur in people who have allergic reactions after direct contact with the pigment.
When used in cosmetics or personal care products, it is important to conduct patch tests to ensure that individuals are not prone to these reactions.
Furthermore, the pigment can sometimes cause respiratory irritation if inhaled as fine particles, especially in industrial settings where the powder is used in the production of large batches.
Certain artificial colorants, including Lake Quinoline Yellow, have been associated with an increased risk of hyperactivity and behavioral problems in children, particularly in combination with other artificial food dyes and preservatives.
Some studies have suggested a link between food colorants and conditions like Attention Deficit Hyperactivity Disorder (ADHD), although this remains controversial.
As a result, some countries have introduced warnings on food products that contain specific synthetic colors, urging parents and caregivers to be cautious when these dyes are consumed in large quantities.
While Lake Quinoline Yellow is generally regarded as safe at low concentrations, there are concerns about the pigment’s toxicity when ingested in large amounts, especially over a long period of time.
Although the pigment is not classified as highly toxic, ingesting significant quantities of it—such as through the consumption of foods or drugs with high levels of artificial colorants—could lead to adverse health effects.
In addition, some studies have suggested that exposure to excessive amounts of certain dyes might contribute to liver or kidney stress in laboratory animals, though these findings have not always been conclusively proven in humans.
