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CAS NO:8006-54-0
EC NO:232-348-6
Lanolin is a waxy fatty substance secreted by sebaceous glands of wooly land animals.
Physical State :Solid
Solubility :Soluble in chloroform
Storage :Store at room temperature
Melting Point :38-44° C
Description
Lanolin oil is a secretion from sheep’s skin.
Lanolin’s similar to human sebum, an oil secreted by the sebaceous glands that you may notice particularly on your nose. Unlike sebum, lanolin contains no triglycerides.
Lanolin is sometimes referred to as “wool fat,” but the term is misleading because it lacks triglycerides needed to be considered a fat.
The purpose of lanolin is to condition and protect sheep’s wool.
This conditioning property is why the substance is now widely used in human cosmetics, skin care, and hair products.
Lanolin oil is extracted by putting sheep’s wool through a centrifuge machine that separates the oil from other chemicals and debris.
The process is performed after the sheep is sheared so the extraction of lanolin causes no harm to sheep.
Benefits
Lanolin is a very good ingredient for someone with dry skin, though it can be a problem for someone with oily or breakout-prone skin. Also, as an animal-derived ingredient, lanolin is sometimes viewed as less favorable in comparison to synthetic or plant-derived alternatives.
Chemical Properties
yellow wax
Chemical Properties
Lanolin is a pale yellow-colored, unctuous, waxy substance with a faint, characteristic odor. Melted lanolin is a clear or almost clear, yellow liquid.
Uses
Lanolin (hydrogenated) is a lanolin derivative.
Uses
Lanolin is an emollient with moisturizing properties and an emulsifier with high water–absorption capabilities.
Lanolin forms a network on the skin’s surface rather than a film, as is the case with petrolatum (Vaseline.). While long-term studies associate a low incidence of allergic reactions to lanolin, it remains a controversial ingredient based on a potential pesticide content and potential comedogenicity.
There is a move among high-quality lanolin manufacturers to produce low-pesticide lanolin and among high-quality cosmetic formulators and manufacturers to use the purist form available.
Lanolin’s comedogenicity potential is increasingly debated as some researchers believe it to be inaccurate, especially when lanolin is used in an emulsion.
Lanolin is a sheep’s wool derivative formed by a fat-like viscous secretion of the sheep’s sebaceous glands. Some consider it a natural wax.
Uses
Lanolin is a lanolin derivative. This is the semisolid fraction of lanolin obtained by physical means from whole lanolin.
Production Methods
Lanolin is a naturally occurring wax-like material obtained from the wool of sheep, Ovis aries Linne′ (Fam. Bovidae).
Crude lanolin is saponified with a weak alkali and the resultant saponified fat emulsion is centrifuged to remove the aqueous phase. The aqueous phase contains a soap solution from which, on standing, a layer of partially purified lanolin separates.
Lanolin is then further refined by treatment with calcium chloride, followed by fusion with unslaked lime to dehydrate the lanolin.
The lanolin is finally extracted with acetone and the solvent is removed by distillation.
Definition
A yellowish viscous substance obtained from wool fat.
Lanolin contains cholesterol and terpene compounds, and is used in cosmetics, in ointments, and in treating leather.
Definition
lanolin: An emulsion of purified wool fat in water, containing cholesteroland certain terpene alcoholsand esters.
Lanolin is used in cosmetics.
Pharmaceutical Applications
Lanolin is widely used in topical pharmaceutical formulations and cosmetics.
Lanolin may be used as a hydrophobic vehicle and in the preparation of water-in-oil creams and ointments. When mixed with suitable vegetable oils or with soft paraffin, it produces emollient creams that penetrate the skin and hence facilitate the absorption of drugs.
Lanolin mixes with about twice its own weight of water, without separation, to produce stable emulsions that do not readily become rancid on storage.
Lanolin is used in a wide variety of creams, ointments and emollients.
Lanolin is often used as protective baby skin treatment and lip balm products such as carmex.
Lanolin acts as a lubricant, shoe polish, rust-preventative coatings and a starting material for the production of cholecalciferol using irradiation.
Lanolin is used to soften and break baseball gloves.
Further, Lanolin is used in various leather treatments by mixing with other ingredients like neatsfoot oil, beeswax and glycerine.
Chemical Name Lanolin (Technical Grade)
Synonyms Wool Fat
CAS Number 8006-54-0
Appearance Dark Yellow Semi-Solid
Storage Room Temperature
Solubility Chloroform (Slightly)
Category Building Blocks; Standards; Miscellaneous;
Applications Lanolin (cas# 8006-54-0) is a useful research chemical.
A yellow fat obtained from sheep's wool.
Lanolin is used as an emollient, cosmetic, and pharmaceutic aid.
Lanolin has been used for thousands of years for its ability to soften and relieve dry, painful, and cracked skin.
Lanolin is popularity peaked in the mid-1900s but is now declining due to its potential to cause skin allergies. Read on to find out more about the uses of lanolin, precautions, and user experiences.
What is Lanolin?
Lanolin comes from wool grease, which is a wax secreted by sheep glands.
Lanolin protects sheep wool from the weather and harsh environments.The ability of lanolin to help cleanse the skin and retain its moisture makes it a common component in cosmetics and medical creams. However, its potential to cause allergies in sensitive people is a potential downside.
To be safe for use, lanolin must contain only a small percentage of fatty acids, moisture, ash, and chloride.
There must be no alkali, ammonia, glycerin, petrolatum, or other impurities present.
Mechanism of Action
Lanolin has strong emulsifying properties. This means that lanolin is able to break large fat particles, mix them with an aqueous phase, and distribute them evenly.
Lanolin also helps with absorption. Because of these properties, lanolin combines well with materials used in cosmetics and pharmaceuticals.
Lanolin also has soothing, cleansing, and lubricating properties. These make it useful in the medical field as a base for creams and ointments.
Uses of Lanolin
1) Dry & Damaged Skin
Medilan is a medical-grade lanolin that is ultra-purified and hypoallergenic, meaning that it causes very little irritation to the skin.
Lanolin increases the water content in your skin. The hypoallergenic, soothing, and moisturizing nature of lanolin makes it useful for eczema and other dry skin conditions.
Topical lanolin decreased the amount of water lost through the skin, the severity of dermatitis, and the bacteria on the outer layer of skin.
Lanolin helps increase new skin growth, which supports wound healing.
Nipple Cream
A traumatic nipple is one of the most common problems for breastfeeding mothers.
Chapped Lips
2) Dry Eyes
Lanolin has an effect on treating dry eyes and corneal abrasions.
Lanolin anhydrous CAS 8006-54-0 is produced from the refining of wool grease which is naturally renewable and is obtained from the shorn wool of live sheep during the wool washing process.
Lanolin is slight yellow ointment,melting point 38-44oC.
Lanolin’s role in nature is to protect wool and skin against the ravages of climate and the environment; it also seems to play a role in skin (integumental) hygiene.
Lanolin and its many derivatives are used extensively in products designed for the protection, treatment and beautification of human skin.
Lanolin conforms to the USP BP standard for cosmetic and pharmaceutical use. And for lanolin cosmetic and pharma use,it is better to use odorless lanolin.
Application
- In medicine, Lanolin is mainly used for dispensing rheumatism paste, zinc oxide adhesive plaster and cream base.
- In cosmetics, lanolin can make skin smooth and tender, the cosmetic grade lanolin can be used for cold cream, anti-wrinkle cream, anti-cracking cream, cream shampoo, conditioner, hair cream, lipstick and advanced soap etc., is a excellent nourishing substance. can make due to the lack of natural moisture and dry or rough skin softening and restoration
Main function
-Lanolin extremely effective emollient in restoring and maintaining the all important hydration (moisture balance) of the stratum corneum, and so prevents drying and chapping of the skin. Equally important, it does not alter the skin's normal transpiration.
-Lanolin has been shown to cause the water in the skin to build up to its normal level of 10-30%, by retarding without completely inhibiting trans-epidermal moisture loss.
-Lanolin has the unique property of absorbing twice its own weight of water.
-Lanolin has the physical properties of increasing adhesion to dry skin, and forming protective films on the skin.
-Lanolin is compatible with most fats and waxes used in cosmetics and pharmaceutical preparations.
-Lanolin is self emulsifying, producing very stable w/o emulsions with water and is often used in this hydrous form.
Lanolin is a Deriv. of unctuous fatty sebaceous secretion of sheep, Ovis aries, consisting of complex mixt. of esters of high m.w. aliphatic, steroid, or triterpenoid alcohol and fatty acids
Lanolin uses and applications include: Soaps; face creams; facial tissues; hair set and suntan preparations; plasticizer for rubber; lubricant for textiles, metalworking compds.; EP agent, slip agent for metalworkingrust preventative coatings; in printing inks; waterproofing agent for leather; chewing gum base; food glazing agent; pharmaceutical emollient, ointment base, filler, vehicle; protectant in diaper rash, hemorrhoidal, antibiotic ointments; rheology control agent, dispersant, cryst. inhibitor for wax in printing inks; antistat, emollient, emulsifier, solvent, cosolvent, plasticizer, wetting agent for cosmetics; surfactant lubricant in food-contact coatings; in paperpaperboard in contact with aqueousfatty foods; defoamer in food-contact paperpaperboard; in cellophane for food packaging; plasticizer in food-contact rubber articles for repeated use
Lanolin, also known as wool wax or wool grease, is a yellow fat obtained from sheep's wool.
Lanolin is used as an emollient, cosmetic, and pharmaceutic aid.
Lanolin contains a complex combination of esters and polyesters, consisting chiefly of cholesteryl and isocholesteryl esters of the higher fatty acids.
Lanolin and its many derivatives are used extensively in both the personal care (e.g., high value cosmetics, facial cosmetics, lip products) and health care sectors such as topical liniments.
Lanolin is also found in lubricants, rust-preventive coatings, shoe polish, and other commercial products.
Lanolin is a relatively common allergen and is often misunderstood as a wool allergy. However, allergy to a lanolin-containing product is difficult to pinpoint and often other products containing lanolin may be fine for use. Patch testing can be done if a lanolin allergy is suspected.
A typical high purity grade of lanolin is composed predominantly of long chain waxy esters (approximately 97% by weight) the remainder being lanolin alcohols, lanolin acids and lanolin hydrocarbons.
An estimated 8,000 to 20,000 different types of lanolin esters are present in lanolin, resulting from combinations between the 200 or so different lanolin acids and the 100 or so different lanolin alcohols identified so far.
Lanolin’s complex composition of long chain esters, hydroxy esters, diesters, lanolin alcohols, and lanolin acids means in addition to it being a valuable product in its own right, it is also the starting point for the production of a whole spectrum of lanolin derivatives, which possess wide-ranging chemical and physical properties.
The main derivatisation routes include hydrolysis, fractional solvent crystallisation, esterification, hydrogenation, and alkoxylation[4] and quaternisation.
Lanolin derivatives obtained from these processes are used widely in both high-value cosmetics and skin treatment products.
Hydrolysis of lanolin yields lanolin alcohols and lanolin acids.
Lanolin alcohols are a rich source of cholesterol (an important skin lipid) and are powerful water-in-oil emulsifiers; they have been used extensively in skin care products for over 100 years.Notably, approximately 40% of the acids derived from lanolin are alpha hydroxy acids (AHAs).
The use of AHAs in skin care products has attracted a great deal of attention in recent years.
Lanolin also called wool fat is a product extracted from the secreted wool grease which is attached to wool.A light yellow or brownish-yellow ointment of anhydrous lanolin.
Lanolin is an ideal raw material for the production of skin care products such as cold cream, anti-wrinkle cream, anti-crack cream, shampoo cream, hair conditioner, hair cream, lip balm and high-grade soap.
Lanolin could used in listed as below:
1.Lanolin used as anti-rust additive.Lubricants, rubber emulsifiers.
2. Lanolin is the ideal raw material for the production of skin care products such as cold cream, anti-wrinkle cream, anti-crack cream, shampoo cream, conditioner, hair cream, lip balm and high grade soap.
3. Lanolin used as an analytical reagent.
4. Jum sugar mastication.
Lanolin also used as the raw materials of edible spices.
5. Lanolin is commonly used as oil-in-water emulsifier and an excellent moisturizing substance.
Application
Lanolin Anhydrous could applied to cosmetic, food, industrial field.
Lanolin is a yellow fat obtained from sheep's wool.
Lanolin is used topically for sore, cracked nipples during breastfeeding.
Description
Anhydrous lanolin is off-white to yellowish brown, viscous, ointment-like substance.
Lanolin is easy to dissolve in chloroform or ether, soluble in hot ethanol, slightly dissolved in ethanol, insoluble in water, but can be mixed evenly with about 2 times of water.
Application
Lanolin is an ideal raw material for the production of cold creams, anti-wrinkle creams, anti-cracking creams, shampoos, conditioners, hair creams, lipsticks and high-end soaps.
Lanolin is often used as a water-in-oil emulsifier and is an excellent moisturizer material.
Lanolin is a product with good water absorption, moisturizing, lipophilic, emulsifying and dispersing properties.
Lanolin is used in cosmetics, medicine, leather, agriculture and other industries.
Lanolin is a natural substance obtained from sheep or goat wool.
Sheep or goat wool, which is purified from mineral salts by simple washing beforehand, is then washed with alkaline solution or soapy water and lanolin accumulated on the surface is obtained.
One can speak of lanolin considered in this way.
This form of lanolin is in the form of an emulsion and is mixed in the form of very small particles. For lanolin in emulsion, it is used in acid precipitation or Ca and Mg precipitation methods other than centrifugation method.
Low-quality allergen applications of lanolin are made.
Lanolin, which can be engineered around the world, will be guessing its small cities, roasting, preparing, and making up of a small enough region to guess, and visitors around the world.
While lanolin draws attention with its appearance in cracks and performance improvement, lanolin used in cracks and cracked heels is also effective in cuticle heater.
It can be experienced on their nipples to lick their babies off their babies or to be used on vehicles in service lanolin service.
Lanolin (from Latin lāna 'wool', and oleum 'oil'), also called wool yolk, wool wax, or wool grease, is a wax secreted by the sebaceous glands of wool-bearing animals.
Lanolin used by humans comes from domestic sheep breeds that are raised specifically for their wool. Historically, many pharmacopoeias have referred to lanolin as wool fat (adeps lanae); however, as lanolin lacks glycerides (glycerol esters), it is not a true fat.
Lanolin primarily consists of sterol esters instead.
Lanolin's waterproofing property aids sheep in shedding water from their coats. Certain breeds of sheep produce large amounts of lanolin.
Lanolin's role in nature is to protect wool and skin from climate and the environment; it also plays a role in skin (integumental) hygiene.
Lanolin and its derivatives are used in the protection, treatment and beautification of human skin.
Composition
A typical high-purity grade of lanolin is composed predominantly of long chain waxy esters (approximately 97% by weight) with the remainder being lanolin alcohols, lanolin acids and lanolin hydrocarbons.
An estimated 8,000 to 20,000 different types of lanolin esters are present in lanolin, resulting from combinations between the 200 or so different lanolin acids and the 100 or so different lanolin alcohols identified so far.
Lanolin’s complex composition of long-chain esters, hydroxyesters, diesters, lanolin alcohols, and lanolin acids means in addition to it being a valuable product in its own right, it is also the starting point for the production of a whole spectrum of lanolin derivatives, which possess wide-ranging chemical and physical properties.
The main derivatisation routes include hydrolysis, fractional solvent crystallisation, esterification, hydrogenation, alkoxylation and quaternisation.
Lanolin derivatives obtained from these processes are used widely in both high-value cosmetics and skin treatment products.
Hydrolysis of lanolin yields lanolin alcohols and lanolin acids.
Lanolin alcohols are a rich source of cholesterol (an important skin lipid) and are powerful water-in-oil emulsifiers; they have been used extensively in skincare products for over 100 years.
Notably, approximately 40% of the acids derived from lanolin are alpha-hydroxy acids (AHAs). The use of AHAs in skin care products has attracted a great deal of attention in recent years. Details of the AHAs isolated from lanolin can be seen in the table below.
Applications
Lanolin ointment
Lanolin and its many derivatives are used extensively in both the personal care (e.g., high value cosmetics, facial cosmetics, lip products) and health care sectors such as topical liniments.
Lanolin is also found in lubricants, rust-preventive coatings, shoe polish, and other commercial products.
Lanolin is a relatively common allergen and is often misunderstood as a wool allergy. However, allergy to a lanolin-containing product is difficult to pinpoint and often other products containing lanolin may be fine for use. Patch testing can be done if a lanolin allergy is suspected.
Lanolin is frequently used in protective baby skin treatment and for sore nipples from breastfeeding.
Lanolin is used commercially in many industrial products ranging from rustproof coatings to lubricants.
Some sailors use lanolin to create slippery surfaces on their propellers and stern gear to which barnacles cannot adhere.
Commercial products (e.g. Lanocote) containing up to 85% lanolin are used to prevent corrosion in marine fasteners, especially when two different metals are in contact with each other and saltwater. The water-repellent properties make it valuable in many applications as a lubricant grease where corrosion would otherwise be a problem.
7-Dehydrocholesterol from lanolin is used as a raw material for producing vitamin D3 by irradiation with ultraviolet light.
Baseball players often use it to soften and break in their baseball gloves (shaving cream with lanolin is popularly used for this).
Anhydrous liquid lanolin, combined with parabens, has been used in trials as artificial tears to treat dry eye.
Anhydrous lanolin is also used as a lubricant for brass instrument tuning slides.
Lanolin can also be restored to woollen garments to make them water and dirt repellent, such as for cloth diaper covers.
Lanolin is also used in lip balm products such as Carmex. For some people, it can irritate the lips.
Lanolin is sometimes used by people on continuous positive airway pressure therapy to reduce irritation with masks, particular nasal pillow masks that can often create sore spots in the nostrils.
Lanolin is a popular additive to moustache wax, particularly 'extra-firm' varieties.
Lanolin is used as a primary lubricating component in aerosol-based brass lubricants in the ammunition reloading process. Mixed warm 1:12 with highly concentrated ethanol (usually 99%), the ethanol acts as a carrier which evaporates quickly after application, leaving a fine film of lanolin behind to prevent brass seizing in resizing dies.
Lanolin, when mixed with ingredients such as neatsfoot oil, beeswax and glycerol, is used in various leather treatments, for example in some saddle soaps and in leather care products.
Lanolin is defined as an emollient used in the skin care and cosmetic industry, in body creams and lotions.
What is Lanolin?
Lanolin is an oily yellow substance made from the secretions (sebum) of sheep's skin glands to soften their wool.
It is a natural, animal product harvested from chopped wool. Unrefined lanolin has been used by various cultures for thousands of years, and refined lanolin has been in ointments for over a hundred years.
What Does Lanolin Do?
Lanolin is a long chain waxy ester that contains cholesterol but has a different composition from human sebum.
More commonly in skincare, it adds a molecule to provide a smoother skin feel. Due to its high oil content, lanolin is occlusive, meaning it prevents water from evaporating from the skin. This keeps the skin moist and helps the skin heal.
Where is Lanolin Cream Used?
Lanolin is generally considered safe for intact skin. But the incidence of lanolin allergy is increasing rapidly, despite being a common ingredient in many products marketed to help heal eczema, burns, abrasions, raw nipples, and post-treatment skin.
Lanolin Cream Benefits
Lanolin cream is the number one nipple cream recommended by mothers and doctors. Clinically tested. Lanolin soothes and protects sore nipples for nursing mothers.
Lanolin Cream is safe for mother and baby. No need to clean before breastfeeding. It is 100 percent natural and hypoallergenic, specially designed for mothers and babies. Contains no preservatives, parabens, fragrances or flavors.
Relieves sore nipples. Intense, rich cream soothes and protects sore nipples. It has clinically proven and ultra pure ingredients. One-component lanolin cream has a unique purification process to remove impurities with no additives.
Lanolin Cream is necessary for breastfeeding. You can use it to soothe and protect sensitive skin. Wash your hands thoroughly. Soften a pea-sized amount between fingers and apply to the entire breast area after each feeding or as needed. Apply before shower to protect sensitive nipples.
Lanolin Cream can also be used for dry and cracked heels, feet, elbows, legs and arms.
Lanolin Cream is applied to moisturize, soften and care for the whole body.
Lanolin is the trade name of an oil obtained from the fat of sheep's wool.
Lanolin is an ester like all oils.
Lanolin is a mixture of clesteral esters and higher fatty acids (palmitate, stearate and aleate), which are the main constituents of lanolin.
Lanolin is a light yellow ointment.
Lanolin is slightly fragrant.
Lanolin is soluble in petroleum ether, ether, chloroform and hot anhydrous alcohol. The melting point of lanolin is 40-42°C.
Lanolin should be protected as it is damaged by light and air. Long storage or an aqueous emulsion of lanolin may hydrolyze and oxidize.
Lanolin can be preserved for a long time using antioxidants.
Lanolin comes in two varieties. One is hydrated (aqueous) lanolin and is yellowish white in color. Aqueous lanolin contains about 30% water and is insoluble in water.
Lanolin is soluble in chloroform and ether. The second is anhydrous lanolin, a semisolid and yellowish substance.
Lanolin is insoluble in water, but gives a mixture of twice its own weight in water, and the lanolin in this mixture is inseparable from water.
Lanolin is soluble in other organic solvents and hot alcohol.
Lanolin is obtained from sheep's wool. Sheep wool is cleaned of mineral salts by simple washing. Then it is washed with soapy water or alkaline solution.
In this wash, the lanolin is removed from the wool.
This soapy water contains 0.5-5% lanolin. In this mixture, lanolin is in the form of emulsion and is separated from the mixture as very small particles. Centrifugation, acid precipitation, or precipitation as Ca and Mg salts can be used to separate lanolin from this emulsifier.
To purify, Lanolin is filtered through special soil strainers. The color is bleached. Sulphate acid, potassium bichromate, chlorine and hydrogen peroxide are used for this process.
In its pure form, lanolin is yellow in color with a strong odor. People who handle sheep and raw wool often feel that their fingers are soft and supple as a result of the wax their skin absorbs, while their hands tend to smell strong and slightly gamey due to the lanolin. In processing, some of this fragrance can be removed, making it more neutral.
During wool processing, most of the lanolin is removed from the wool, but some can be left to provide natural waterproofing. After the beeswax is extracted from the wool, it can be purified for commercial use.
IUPAC names
LANOLIN
Lanolin
lanolinlanol
SYNONYMS:
2598-99-4 [RN]
309-376-3 [EINECS]
Hexadecanoic acid, octadecyl ester [ACD/Index Name]
MFCD00056224
OCTADECYL HEXADECANOATE
Octadecyl palmitate [ACD/IUPAC Name]
Octadecylpalmitat [German] [ACD/IUPAC Name]
Palmitate d'octadécyle [French] [ACD/IUPAC Name]
palmitic acid stearyl ester
Palmitic acid, octadecyl ester
STEARYL PALMITATE
[2598-99-4]
100231-74-1 [RN]
100231-75-2 [RN]
17661-50-6 [RN]
1-Hexadecyl hexadecanoate
2239-78-3 [RN]
4-02-00-01168 (Beilstein Handbook Reference) [Beilstein]
4-02-00-01220 (Beilstein Handbook Reference) [Beilstein]
540-10-3 [RN]
8006-54-0 [RN]
CETEARYL OLIVATE
CETEARYL PALMITATE
Cetin
CETYL ESTERS WAX
CETYL PALMITATE
