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Lauramide DEA (Lauric Acid Diethanolamide), is a nonionic surfactant widely used in personal care and household products.
Lauramide DEA (Lauric Acid Diethanolamide) is derived from lauric acid, a fatty acid commonly found in coconut oil, and diethanolamine.
Lauramide DEA (Lauric Acid Diethanolamide) typically appears as a pale yellow to amber liquid or waxy solid, depending on temperature.
CAS Number: 120-40-1
Molecular Formula: C16H33NO3
Molecular Weight: 287.44
EINECS Number: 204-393-1
Synonyms: N,N-Bis(2-hydroxyethyl)dodecanamide, 120-40-1, Lauric diethanolamide, Lauramide DEA, Lauric acid diethanolamide, Lauryl diethanolamide, Lauroyl diethanolamide, Standamidd ld, Alkamide LE, Rolamid cd, Condensate PL, Dodecanamide, N,N-bis(2-hydroxyethyl)-, Comperlan LD, Mackamide LL, Standamid LD, Diethanollauramide, Hetamide ML, Mackamide LLM, Richamide STD, Crillon LDE, Empilan LDE, Ethylan MLD, Rewomid DLMS, Stepan LDA, N,N-Bis(2-hydroxyethyl)lauramide, Coco diethanolamide, Varamid ml 1, Varamide ML 1, Lauroyldiethanolamine, Clindrol 100L, Clindrol 101CG, Clindrol 203CG, Clindrol 210CGN, Monamide 150LW, Richamide 6310, Super Amide L-9A, Super Amide L-9C, Synotol L-60, Unamide J-56, Aminon L 02, Onyxol 345, Bis(2-hydroxyethyl)lauramide, N,N-Diethanollauramide, N,N-Diethylollauramide, Rewomid DL 203/S, Ninol P-621, Steinamid DL 203 S, N,N-Bis(hydroxyethyl)lauramide, Ninol 4821, Diethanolamine lauroylamide, Clindrol superamide 100L, Crillon L.D.E., Lauric acid diethanolamine condensate, N,N-Diethanollauric acid amide, N,N-DI(2-HYDROXYETHYL)LAURAMIDE, EMID 6511, NCI-C55323, N,N-Bis(2-hydroxyethyl)laurylamide, N,N-Bis(2-hydroxyethyl)lauroylamide, Lauric acid diethanolamine, C11DEA, I29I2VHG38, 72968-36-6, DTXSID5025491, Lauric acid diethanolamine condensate (1:1), LDE, NCGC00181001-01, Lankrostat JP, Incromide LR, Lauramido DEA, Lalmin D, LDA (surfactant), Ninol aa62, Clindrol 200L, Chemistat 2500, Ninol aa-62 extra, Chemstat LD 100, Monamid 150-LW, Caswell No. 519A, Duspar LA 2000, CCRIS 4662, lauric diethanol amide, HSDB 5586, N,N-Bis(beta-hydroxyethyl)lauramide, EINECS 204-393-1, EPA Pesticide Chemical Code 079018, Methyl laurate-diethanolamine condensate, BRN 1791417, UNII-I29I2VHG38, Clindrol, AI3-09484, Hartamide LDA, Stremid K, Ablumide LDE, diethanol lauramide, Mackamide L10, Schercomid SL-EX, Carsamide SAL-7, Dehydat 10, EINECS 277-136-4, lauric-diethanolamide, Alkamide 327, MFCD00045982, Schercomid SL-Extra, Witcamide 5138, Witcamide 5195, Clindrol 200 L, Monamid 150 LW, Ninol AA 62 extra, N-Lauroyldiethanolamine, Monamid 150-LMWC, Ninol 30-LL, Ninol AA 62, Pionin D 1110, N,N-Diethanoldodecanamide, N-Dodecanoyldiethanolamine, Diethanolamide lauric acid, C11-Coconut diethanolamide, Diethanol lauric acid amide, EC 204-393-1, Lauric acid-diethanol amide, 4-04-00-01539 (Beilstein Handbook Reference), MLS006010225, LAURAMIDE DEA [VANDF], SCHEMBL284367, DTXCID405491, Schercomid 1214 (Salt/Mix), Diethanolamide of methyl laurate, LAURAMIDE DEA [WHO-DD], CHEMBL1996872, EMID 6541, CHEBI:143726, DTXSID101022608, LAURIC DIETHANOLAMIDE [II], DIETHANOL LAURAMIDE [VANDF], Lauramide, N,N-bis(hydroxyethyl)-, Tox21_112653, LMFA08040058, LAURAMIDE DIETHANOLAMIDE (DEA), AKOS014510507, lauric acid diethanolamide, AldrichCPR, CS-W005513, N,N-Bis(.beta.-hydroxyethyl)lauramide, AS-10219, CAS-120-40-1, SMR001826330, 1ST161670, N pound notN-Bis(2-hydroxyethyl)dodecanamide, NS00010591, G56359, N,N-DI(2-HYDROXYETHYL)LAURAMIDE [HSDB], SBI-0654207.0001, EN300-7489805, 1ST161670-1000, SR-01000944847, SR-01000944847-1, W-109444, BRD-K11548689-001-01-6, Q27280284, Z1262465391, Lauric acid diethanolamide Solution in Methanol, 1000mug/mL, N,N-Bis(2-hydroxyethyl)dodecanamide, 9CI. N,N-Bis(2-hydroxyethyl)lauramideEMALEX NN-7,EMALEX NN-9,LAUROYL DIETHANOLAMIDE,LAURYL DIETHANOLAMIDE,LAURIC DIETHANOLAMIDE,LAURIC ACID DIETHANOLAMIDE,N,N-BIS(2-HYDROXYETHYL)DODECANAMIDE,N,N-BIS(2-HYDROXYETHYL)LAURAMIDE
Lauramide DEA (Lauric Acid Diethanolamide) is a fatty amide.
Lauramide DEA (Lauric Acid Diethanolamide) is a compound made from a saturated fatty acid called lauric acid and diethanolamine or DEA, an ingredient in some cosmetic products that functions as a wetting agent.
Combinations of fatty acids and DEA like lauramide DEA are referred to as diethanolamides.
The diethanolamide lauramide DEA is an ingredient in some personal care products including shampoo, hair coloring products, hand soap, bubble baths, bath gels and lotions.
In cosmetic and personal care products, Lauramide DEA (Lauric Acid Diethanolamide) enhances a product’s ability to form and maintain foam.
Lauramide DEA (Lauric Acid Diethanolamide) also increases the viscosity or thickness of products.
This gives them a more substantial feel.
Without a viscosity-enhancing agent, shampoos and other personal care products would be considered too “runny” by some.
Viscosity increasing agents like Lauramide DEA (Lauric Acid Diethanolamide) are often combined with surfactants to maximize the texture and performance of cosmetic and personal care products that foam like shampoo and bubble bath.
Lauramide DEA (Lauric Acid Diethanolamide) also serves as an emulsion stabilizer that helps to keep water-soluble and oil-soluble ingredients together in a product.
Lauramide DEA (Lauric Acid Diethanolamide)s are found in cosmetic and personal care products in concentrations of between 1 and 10%.
At these concentrations, the Cosmetic Ingredient Review Expert Panel, a group of independent experts that looks at the safety of cosmetic ingredients, deems Lauramide DEA (Lauric Acid Diethanolamide) to be safe.
This assumes that lauramide DEA isn’t contamined with other ingredients called nitrosating agents.
Nitrosating agents interact with lauramide DEA to form nitrosamines, chemicals linked with an increased risk of cancer.
This can happen during the manufacture of a product or during storage.
Such ingredients must be excluded from products that contain diethanolamides like Lauramide DEA (Lauric Acid Diethanolamide), although there are still concerns about contamination.
Topically, Lauramide DEA (Lauric Acid Diethanolamide) can cause mild skin irritation.
There are also reports of contact dermatitis and allergic reactions in some people.
Diethanolamides are common ingredients used in cosmetics to act as a foaming agents or as emulsifiers.
Chemically, they are amides formed from diethanolamine and carboxylic acids, typically fatty acids.
Lauramide DEA (Lauric Acid Diethanolamide)s are viscous liquids or waxy solids.
These ingredients are fatty acids derivatives of diethanolamine (DEA).
In cosmetics and personal care products, these ingredients are used in the formulation of shampoos, hair dyes, bath products, and lotions.
Lauramide DEA (Lauric Acid Diethanolamide) helps stabilize and thicken foam in shampoos, body washes, and liquid soaps.
Lauramide DEA (Lauric Acid Diethanolamide) increases the thickness of formulations, giving products a creamier feel.
Lauramide DEA (Lauric Acid Diethanolamide) assists in mixing water with oils and helps to cleanse surfaces by reducing surface tension.
For its thickening and foaming properties, Body Washes and Soaps: As a foaming agent and emollient.
In formulations where a creamy or foamy consistency is desired.
While Lauramide DEA (Lauric Acid Diethanolamide) is effective and popular in many applications, there are safety considerations. Diethanolamine, a component, can react with nitrosating agents to form nitrosamines, which are potentially carcinogenic.
As a result, regulatory bodies like the FDA and EU restrict the presence of nitrosamines in products.
Manufacturers are encouraged to follow guidelines to minimize potential contaminants and use Lauramide DEA (Lauric Acid Diethanolamide) within safe concentrations.
The lauric acid backbone provides a hydrophobic tail, which is responsible for interacting with oils and lipids.
The diethanolamine portion of the molecule has two hydroxyl (-OH) groups, contributing hydrophilic properties.
This part allows the compound to dissolve in water while maintaining emulsification properties.
These structural features give Lauramide DEA (Lauric Acid Diethanolamide) its surfactant properties, allowing it to interact with both oil and water.
This balance of hydrophilic and hydrophobic parts makes it highly effective at reducing surface tension, improving the cleansing action in aqueous solutions.
In facial cleansers, Lauramide DEA (Lauric Acid Diethanolamide) offers a mild cleansing effect without stripping away natural oils, which is critical for dry and sensitive skin types.
In hair care products, it enhances the consistency, giving products a creamy appearance.
Additionally, it helps to trap and stabilize air, giving the impression of a richer, foamy lather.
While less commonly used in leave-on products, Lauramide DEA (Lauric Acid Diethanolamide) can sometimes be found in certain lotions for its emulsifying properties, though regulatory concerns are limiting its use in this area.
Lauramide DEA (Lauric Acid Diethanolamide) is added to improve soil dispersion and emulsify oils, helping to lift dirt and oil from fabrics.
In industrial formulations, it provides a stable emulsion that can tackle grease and oil, beneficial for cleaning tough, greasy surfaces.
In car washes and polishes, Lauramide DEA (Lauric Acid Diethanolamide) enhances foam stability, creating a thick lather that adheres well to surfaces, ensuring a longer contact time for cleaning.
Lauramide DEA (Lauric Acid Diethanolamide)'s production process involves diethanolamine (DEA), which under certain conditions can react with nitrosating agents to form nitrosamines, known to have carcinogenic potential.
Though Lauramide DEA (Lauric Acid Diethanolamide) itself is not harmful, these trace nitrosamines can pose health risks, especially with prolonged exposure.
The EU restricts the use of Lauramide DEA (Lauric Acid Diethanolamide) in cosmetics and personal care products unless nitrosamine contamination is strictly controlled and minimized.
Lauramide DEA (Lauric Acid Diethanolamide) must meet stringent guidelines for purity and low nitrosamine levels.
Lauramide DEA (Lauric Acid Diethanolamide) has set limits on allowable nitrosamine levels in products and encourages formulations to be tested for nitrosamines, especially in rinse-off products.
Some regulatory agencies worldwide are pushing for transparency around Lauramide DEA (Lauric Acid Diethanolamide)-containing ingredients, and some companies have begun reformulating products to eliminate Lauramide DEA in favor of safer alternatives.
Melting point: 45-48℃
Boiling point: 429.73°C (rough estimate)
Density 0.9610 (rough estimate)
vapor pressure: 0.002Pa at 20℃
refractive index: 1.4545 (estimate)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 14.13±0.10(Predicted)
color: White to Off-White
Water Solubility: 49.91mg/L at 20℃
LogP. 3.48
Lauramide DEA (Lauric Acid Diethanolamide) is synthesized through a reaction between lauric acid, a medium-chain fatty acid, and diethanolamine.
This combination results in a compound with both hydrophilic (water-attracting) and hydrophobic (water-repelling) ends, enabling it to bridge water and oil components in various products.
Lauramide DEA (Lauric Acid Diethanolamide) enhances the texture and viscosity of liquid formulations, allowing them to feel rich and creamy.
In shampoos, Lauramide DEA (Lauric Acid Diethanolamide) contributes to a luxurious feel by increasing thickness and providing a stable, dense foam.
This ingredient boosts foam stability, ensuring that the foam lasts longer, which is particularly valued in products like hand washes, shampoos, and body gels.
Its ability to form stable bubbles improves user experience in cleansing routines.
Lauramide DEA (Lauric Acid Diethanolamide) is gentle on the skin compared to harsher surfactants.
Its mild nature makes it ideal for personal care products like facial cleansers, moisturizing body washes, and sensitive skin products, where it supports cleaning without excessive dryness.
The lauric acid component in Lauramide DEA (Lauric Acid Diethanolamide) has emollient effects, which means it can help to soften and condition the skin or hair, reducing dryness after use.
Due to its creamy, foaming, and gentle cleansing properties, Lauramide DEA (Lauric Acid Diethanolamide) is extensively used in: Shampoos and Conditioners: It not only thickens the formula but also provides a rich lather that enhances user satisfaction.
Known for its stable foam, it’s a preferred ingredient for products where prolonged foaming is desirable.
Facial Cleansers: For gentle cleansing, Lauramide DEA (Lauric Acid Diethanolamide) offers a soft, non-stripping clean, suitable for sensitive skin formulations.
Lauramide DEA (Lauric Acid Diethanolamide) enhances foam and viscosity, giving the product a thicker, more luxurious feel.
In surface cleaners, it helps reduce surface tension, allowing the solution to spread more evenly across surfaces for improved cleaning efficacy.
Lauramide DEA (Lauric Acid Diethanolamide) is used in some industrial applications where stable foaming or emulsification is necessary.
Its ability to withstand various pH levels makes it adaptable for specialty cleaners and formulations.
Lauramide DEA (Lauric Acid Diethanolamide) does come with some health considerations.
Lauramide DEA (Lauric Acid Diethanolamide), the amine component of Lauramide DEA, can react with certain ingredients to form nitrosamines, compounds identified as potential carcinogens.
Though Lauramide DEA itself is not classified as carcinogenic, the risk of nitrosamine formation has prompted regulatory agencies.
Regulations in the EU, FDA, and other regions restrict nitrosamine levels in cosmetics and require manufacturers to take measures to avoid contamination.
Some regions discourage its use in leave-on products like lotions, due to the potential for longer skin exposure.
As an organic compound, Lauramide DEA can break down in wastewater treatment processes. However, biodegradation rates vary, and in large concentrations, it could contribute to aquatic toxicity.
To mitigate environmental impact, manufacturers are moving towards safer, biodegradable alternatives where possible.
Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents.
They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones.
Alcohols exhibit both weak acid and weak base behavior.
They may initiate the polymerization of isocyanates and epoxides.
Organic amides/imides react with azo and diazo compounds to generate toxic gases.
Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents.
Amides are very weak bases (weaker than water).
Lauramide DEA (Lauric Acid Diethanolamide) imides are less basic yet and in fact react with strong bases to form salts.
That is, they can react as acids.
Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile.
The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Uses Of Lauramide DEA (Lauric Acid Diethanolamide):
Lauramide DEA (Lauric Acid Diethanolamide) is used in preparation method of water-absorbent resin for improving anti-caking performance.
Lauramide DEA (Lauric Acid Diethanolamide) is used as a thickener and foam stabilizer to create a rich, luxurious lather and improve texture.
Enhances foam production and stability, giving a creamy feel while gently cleansing the skin.
Provides mild cleansing that doesn’t strip natural oils, suitable for sensitive or dry skin.
Creates long-lasting bubbles that enhance the bathing experience.
Lauramide DEA (Lauric Acid Diethanolamide) adds thickness and foam stability, improving the cleaning experience and effectiveness.
Helps emulsify and lift dirt and grease from surfaces, making it easier to wipe away residue.
Contributes to foam formation and helps disperse oils and dirt from fabrics.
Lauramide DEA (Lauric Acid Diethanolamide) is used to stabilize foam, creating a dense lather that adheres to the vehicle’s surface, allowing for improved cleaning action.
Helps in breaking down and emulsifying oils and greases, making it useful for industrial cleaning applications.
Added to foaming disinfectants and sanitizers to maintain foam and improve spreadability.
Occasionally used as a secondary emulsifier in creams and lotions, helping to blend water and oil-based ingredients.
Increases thickness and creaminess, enhancing the application experience for conditioning hair products.
Lauramide DEA (Lauric Acid Diethanolamide) is used as a minor additive in certain industrial emulsions where stable, water-oil emulsification is needed.
Provides a mild cleaning agent in textile and leather processing, assisting in removing oils and other residues.
Lauramide DEA (Lauric Acid Diethanolamide) provides a creamy, stable foam, enhancing the sensory experience and making the product easier to distribute through hair.
Its thickening effect gives shampoos a more luxurious feel, helping to create body and volume.
Known for its mildness and ability to boost foam, Lauramide DEA (Lauric Acid Diethanolamide) adds richness to the lather while being gentle on the skin, reducing the likelihood of dryness or irritation.
Due to its gentle cleansing action, Lauramide DEA (Lauric Acid Diethanolamide) is often included in facial cleansers for sensitive or dry skin types, allowing effective cleansing without over-drying.
It contributes to the dense foam in shaving products, helping the formula adhere to the skin and providing a smooth glide for razors.
It stabilizes foam in bath bombs and bubble baths, creating a dense, lasting layer of bubbles that enhances the bathing experience.
In hand washes, Lauramide DEA (Lauric Acid Diethanolamide) helps generate a thick, stable foam that is ideal for frequent washing, providing a satisfying lather without being overly harsh.
Lauramide DEA (Lauric Acid Diethanolamide)’s foaming and grease-cutting properties make it effective in dish soaps, helping to emulsify oils and improve the removal of food residues from dishes.
In multipurpose sprays and surface cleaners, it acts as an emulsifier and surfactant, helping to remove dirt and grease from various household surfaces, like countertops and sinks.
Lauramide DEA (Lauric Acid Diethanolamide) assists in creating a stable foam and enhances the detergent’s ability to dissolve and lift oils, dirt, and residues from fabrics, improving overall cleaning power.
In foaming toilet bowl cleaners, Lauramide DEA (Lauric Acid Diethanolamide) helps create a thick foam that clings to surfaces, allowing active ingredients to work effectively on stains and limescale.
Lauramide DEA (Lauric Acid Diethanolamide) stabilizes foam in car wash formulas, allowing it to cling to vehicle surfaces for longer cleaning action.
This is especially beneficial for products designed for pressure washers or foam cannons.
For industrial cleaning, it acts as an emulsifier to break down and remove grease, oil, and grime from machinery and equipment.
This improves the cleaning process, especially in sectors like automotive and manufacturing.
In specialized cleaning formulations, Lauramide DEA (Lauric Acid Diethanolamide) helps remove stubborn stains and oils from porous materials like concrete and stone, by enabling better penetration and emulsification of grease and dirt.
In certain topical pharmaceutical preparations, Lauramide DEA (Lauric Acid Diethanolamide) is sometimes used to help stabilize emulsions, though alternatives are often preferred in this industry due to DEA-related safety concerns.
In some agricultural applications, Lauramide DEA (Lauric Acid Diethanolamide) can be used as an emulsifier in sprays, helping to disperse active ingredients evenly across crops.
In textile and leather processing, Lauramide DEA (Lauric Acid Diethanolamide) is used in formulations to help clean and soften fibers by emulsifying oils and residues from processing.
Lauramide DEA (Lauric Acid Diethanolamide) is particularly useful in pre-treatment stages where fabric needs to be cleaned before further processing.
In many products, Lauramide DEA (Lauric Acid Diethanolamide) is included specifically for its ability to stabilize and maintain foam consistency over time.
This improves user experience, particularly in personal care products where rich foam is desired.
Lauramide DEA (Lauric Acid Diethanolamide) is frequently used to adjust the viscosity of liquid products, such as shampoos and dishwashing liquids, adding a creamy texture and reducing the need for additional thickeners.
Lauramide DEA (Lauric Acid Diethanolamide) helps oil and water-based ingredients blend seamlessly in emulsions.
This property is especially useful in products where oil and water phases are difficult to stabilize, such as creams and lotions.
In “green” and eco-friendly formulations, Lauramide DEA (Lauric Acid Diethanolamide) is often scrutinized, but it’s still sometimes included because it is biodegradable.
However, manufacturers are developing DEA-free alternatives that match Lauramide DEA (Lauric Acid Diethanolamide)’s performance in an environmentally safer way.
Lauramide DEA (Lauric Acid Diethanolamide) is primarily used in rinse-off products, where minimal residue remains on the skin or surfaces.
This helps mitigate health concerns related to nitrosamines, which are typically more of a risk in leave-on products.
Because of safety concerns, some formulators are replacing Lauramide DEA (Lauric Acid Diethanolamide) with surfactants like cocamidopropyl betaine, sodium cocoyl glutamate, or lauryl glucoside, which offer similar foaming and thickening benefits without the DEA-related risks.
Safety Profile Of Lauramide DEA (Lauric Acid Diethanolamide):
Lauramide DEA (Lauric Acid Diethanolamide) itself isn’t directly classified as a carcinogen. However, during its manufacturing and under certain conditions (like reactions with nitrosating agents), it can produce nitrosamines, which are known carcinogens.
Nitrosamines can form as by-products, particularly in products stored for long periods, and are associated with an increased risk of cancer, especially in the liver and kidneys.
Lauramide DEA (Lauric Acid Diethanolamide) can cause mild to moderate irritation to the skin and eyes, especially in high concentrations.
This is particularly a concern for workers who handle it in its concentrated form during manufacturing or formulation processes.
Some people may experience allergic contact dermatitis or sensitization to Lauramide DEA (Lauric Acid Diethanolamide), leading to itching, redness, and rashes upon skin contact, particularly in individuals with sensitive skin.
When used in aerosol or spray products, Lauramide DEA (Lauric Acid Diethanolamide) could be inhaled, leading to potential respiratory irritation.
Prolonged exposure to aerosols containing Lauramide DEA may cause respiratory issues, particularly for workers in production settings.
