LAURYL AMINE OXIDE

Lauryl amine oxide is a non-ionic surfactant that enhances the cleaning efficiency of various products by improving foam stability and viscosity.
Lauryl amine oxide is an amine oxide-based zwitterionic surfactant with a C12 (dodecyl) alkyl tail.
Lauryl amine oxide is widely valued for its stability over a broad pH range and its ability to improve overall formulation performance.

CAS Number: 1643-20-5
EC Number: 216-700-6
Molecular Formula: C14H31NO
Molecular Weight: 229.40 g/mol

Synonyms: N,N-dimethyldodecan-1-amine oxide, DDNO, N,N-Dimethyldodecylamine-N-oxide, LAURYL DIMETHYLAMINE-N-OXIDE, Aromox dmmc-W, Dimethyllaurylamine oxide, N,N-Dimethyldodecylamine oxide, Amonyx AO, Refan [Russian], N,N-dimethyldodecan-1-amine N-oxide, N,N-Dimethyldodecylamine N-oxide, 30% solution in water, Refan, Oxyde de dimethyllaurylamine, N,N-Dimethyl-dodecylaminoxid, C14H31NO, Cyclomox L, Rhodamox L, Softamine L, Genaminox LA, Laurylamine oxide, lauryl dimethylamine oxide, UNII-4F6FC4MI8W, N,N-Dimethyl-1-dodecylamine N-oxide, N-Lauryldimethylamine N-oxide, HSDB 5451, N-Lauryl-N,N-dimethylamine oxide, NCI-C55129, EINECS 216-700-6, N,N-Dimethyl-dodecylaminoxid [Czech], Oxyde de dimethyllaurylamine [French], Dodecylamine, N,N-dimethyl-, N-oxide, Lauryl dimethyl amine oxide, BRN 1769927, 4F6FC4MI8W, 1-Dodecanamine, N,N-dimethl-, N-oxide, amine oxide, dodecyl(dimethyl)-, CHEMBL1233973, MFCD00002049, N,N-Dimethyl-1-dodecanamine-N-oxide

Lauryl amine oxide is an amphoteric (zwitterionic) surfactant derived from lauryl (C12) fatty amines, commonly used in cleaning and personal care formulations.
Lauryl amine oxide provides excellent foam boosting, viscosity enhancement, and mild cleansing properties, making it highly effective in combination with anionic and nonionic surfactants.
Lauryl amine oxide is widely valued for its stability over a broad pH range and its ability to improve overall formulation performance.

Lauryl amine oxide is a chemical compound commonly used in cosmetics as a surfactant and cleansing agent.
Lauryl amine oxide belongs to the class of amine oxide surfactants and is derived from lauric acid, which is found in coconut oil or other vegetable oils.

Lauryl amine oxide appears as a clear to pale yellow liquid with a mild odor.
Lauryl amine oxide has excellent foaming and emulsifying properties, making it suitable for various personal care products such as shampoos, body washes, and facial cleansers.

As a surfactant, Lauryl amine oxide helps to remove dirt, oil, and impurities from the skin and hair, leaving them clean and refreshed.
The chemical formula of Lauryl amine oxide is C14H31NO.

Lauryl amine oxide is an amine oxide-based zwitterionic surfactant with a C12 (dodecyl) alkyl tail.
Lauryl amine oxide is one of the most commonly used surfactants of this type.

Like other amine oxide-based surfactants, lauryl amine oxide is antimicrobial, effective against common bacteria such as S. aureus and E. coli, but it is also non-denaturing and can be used to dissolve proteins.
Lauryl amine oxide is a plant metabolite and has a detergent role.

Lauryl amine oxide is derived from the hydride of a dodecane.
Lauryl amine oxide is a standard liquid surfactant.
Lauryl amine oxide appears as a clear yellow liquid.

Lauryl amine oxide is a non-ionic surfactant that enhances the cleaning efficiency of various products by improving foam stability and viscosity.
This makes it an essential ingredient in liquid hand dishwashing detergents, mild industrial cleaners, and hard surface cleaners.

Additionally, lauryl amine oxide exhibits mild cationic behavior at low pH, which contributes to its effectiveness in caustic cleaners and metal cleaners.
Lauryl amine oxide's ability to act as an emulsifier and conditioning agent further broadens its application in the HI&I sector.
Overall, lauryl amine oxide's multifunctional nature makes it a valuable component in maintaining cleanliness and hygiene across various settings.

Lauryl amine oxide is a quaternary ammonium compound that serves as a surfactant and is commonly used in various industrial and consumer applications.
Lauryl amine oxide is characterized by its amphiphilic nature, possessing both hydrophilic and hydrophobic properties, which allows it to effectively reduce surface tension and enhance wetting properties in formulations.

Lauryl amine oxide typically appears as a colorless to pale yellow liquid and is soluble in water, making it suitable for use in detergents, personal care products, and emulsifiers.
Lauryl amine oxide exhibits good foaming properties and is known for its mildness, making it a popular choice in formulations for sensitive skin.

Additionally, Lauryl amine oxide has antimicrobial properties, which can contribute to the preservation of products.
However, like many surfactants, Lauryl amine oxide should be handled with care, as it can cause irritation to the skin and eyes upon direct contact.
Overall, Lauryl amine oxide's versatility and effectiveness make it a valuable ingredient in various chemical formulations.

Lauryl amine oxide is a nonionic/amphoteric surfactant compatible with all classes of surfactants: anionic, nonionic, amphoteric and cationic.
Lauryl amine oxide provides high foaming and thickening properties and is stable in most pH ranges, including stability in peroxide and hypochlorite solutions.
Additionally, Lauryl amine oxide can alleviate the irritating effects of anionic surfactants.

Uses of Lauryl Amine Oxide:
Lauryl amine oxide finds various applications in the cosmetics industry due to its surfactant properties.
Lauryl amine oxide is commonly used in skincare and hair care products as a foaming agent and cleansing ingredient.

Lauryl amine oxide helps to create a rich lather and effectively removes dirt, oil, and impurities from the skin and hair.
Lauryl amine oxide is often found in shampoos, body washes, facial cleansers, and other cleansing formulations.

Additionally, Lauryl amine oxide can contribute to the stability and texture of cosmetic products, acting as an emulsifier and thickening agent.
Lauryl amine oxide's versatile nature makes it a valuable ingredient for formulating effective and enjoyable cosmetic products.

Lauryl amine oxide is used in shampoos, body washes, and facial cleansers to enhance foam and improve mild cleansing performance.
Lauryl amine oxide is applied in dishwashing liquids and household cleaning products to boost foam and grease removal efficiency.

Lauryl amine oxide is utilized in hard surface cleaners and disinfectant formulations to improve wetting and cleaning action.
Lauryl amine oxide is used in industrial and institutional cleaning systems for its stability and compatibility with other surfactants.
Lauryl amine oxide is incorporated into textile cleaning formulations to enhance detergency and foam stability.

Detergents and Surfactants:
They have excellent cleaning and dispersing capabilities and are commonly used in detergents, cleaning agents, fabric softeners, shampoos, and other products.

Emulsifiers:
They can form a stable emulsifying system at the oil-water interface, therefore they are widely used in the preparation of emulsifiers.

Foaming Agents:
They can produce rich foam and are commonly used in detergents and personal care products.

Industry Uses:
Other (specify)
Emulsifier
Intermediate
Foamant
Surface active agents
Surfactant (surface active agent)

Consumer Uses:
Surface active agents
Surfactant (surface active agent)
Emulsifier
Other (specify)

Advantages of Lauryl Amine Oxide:
Lauryl amine oxide provides excellent foam boosting and foam stability in surfactant systems.
Lauryl amine oxide enhances viscosity and improves formulation texture.

Lauryl amine oxide offers good compatibility with anionic, nonionic, and cationic surfactants.
Lauryl amine oxide delivers mildness and low irritation in personal care products.

Lauryl amine oxide improves detergency and grease removal efficiency.
Lauryl amine oxide remains stable over a wide pH range.
Lauryl amine oxide supports formulation performance in both household and industrial cleaning applications.

Origin of Lauryl Amine Oxide:
Lauryl amine oxide is typically synthesized by reacting lauric acid or lauryl alcohol with hydrogen peroxide under controlled conditions.
This reaction leads to the formation of the amine oxide, specifically Lauryl amine oxide.
The resulting compound is then purified and used as a surfactant in various cosmetic and personal care products.

Production of Lauryl Amine Oxide:
Lauryl amine oxide is produced by the oxidation of lauryl dimethylamine using hydrogen peroxide as the oxidizing agent.
Lauryl dimethylamine, typically derived from natural fatty alcohols obtained from coconut or palm kernel oil, is reacted with hydrogen peroxide under controlled temperature and pH conditions.

The oxidation process converts the tertiary amine into the corresponding amine oxide without significantly altering the carbon chain structure.
The reaction mixture is then stabilized, and excess hydrogen peroxide is removed or decomposed.
The final product is adjusted to the desired concentration and purified if necessary, resulting in a clear to slightly yellow liquid suitable for use in personal care and cleaning formulations.

Stability and Reactivity of Lauryl Amine Oxide:

Chemical stability:
Lauryl amine oxide is stable under normal conditions of use, handling, and storage.

Reactivity:
Lauryl amine oxide shows low reactivity.
May react with strong oxidizing agents.

Conditions to avoid:
Excessive heat.
Contamination.
Extreme pH conditions.

Incompatible materials:
Strong oxidizers.
Strong reducing agents.

Hazardous decomposition products:
Thermal decomposition may produce carbon oxides (CO, CO₂).
Nitrogen-containing fumes may be released.

Handling and Storage of Lauryl Amine Oxide:

Handling:
Handle in accordance with good industrial hygiene practices.
Avoid contact with eyes.
Avoid prolonged skin exposure.

Storage:
Store in a cool, dry, well-ventilated area.
Keep containers tightly closed.

Storage conditions:
Protect from extreme temperatures.
Protect from contamination.

Packaging materials:
Use compatible plastic or lined containers.

Shelf life:
Stable for extended periods under recommended storage conditions.

First Aid Measures of Lauryl Amine Oxide:

Inhalation:
Move to fresh air.
Seek medical attention if irritation persists.

Skin contact:
Wash thoroughly with water and soap.

Eye contact:
Rinse cautiously with water for several minutes.
Seek medical advice if irritation continues.

Ingestion:
Rinse mouth.
Do not induce vomiting.
Seek medical advice if necessary.

Most important symptoms:
Eye and skin irritation may occur.

Firefighting Measures of Lauryl Amine Oxide:

Suitable extinguishing media:
Water spray.
Foam.
Dry chemical powder.
Carbon dioxide (CO₂).

Specific hazards:
May release irritating fumes.
Nitrogen oxides may be formed during combustion.

Protective equipment for firefighters:
Use self-contained breathing apparatus.
Wear protective clothing.

Special precautions:
Avoid inhalation of combustion gases.

Accidental Release Measures of Lauryl Amine Oxide:

Personal precautions:
Avoid contact.
Ensure adequate ventilation.

Environmental precautions:
Prevent large quantities from entering drains or water systems.

Methods for cleanup:
Absorb with inert material such as sand or vermiculite.
Collect for disposal.

Exposure Controls / Personal Protection of Lauryl Amine Oxide:

Occupational exposure limits:
Not specifically established.

Engineering controls:
Provide adequate general ventilation.

Respiratory protection:
Not normally required.
Use mask if aerosol or mist is generated.

Hand protection:
Use chemical-resistant gloves.

Eye protection:
Use safety goggles.

Skin protection:
Wear protective clothing for prolonged exposure.

Hygiene measures:
Wash hands after handling.
Avoid contact with eyes and skin.

Identifiers of Lauryl Amine Oxide:
CAS Number: 1643-20-5
EC Number: 216-700-6
Molecular Formula: C₁₄H₃₁NO
Molecular Weight: 229.40 g/mol
Chemical Class: Amine oxide surfactant
Structure Type: Tertiary amine oxide (R–N⁺(CH₃)₂–O⁻)
Origin: Synthetic (derived from lauryl dimethylamine)
Physical Form: Liquid

CAS Number: 1643-20-5
Chem/IUPAC Name: Dodecyldimethylamine oxide
EINECS/ELINCS No: 216-700-6
COSING REF No: 78481

Properties of Lauryl Amine Oxide:
Appearance: Clear to pale yellow liquid
Odor: Mild, characteristic
pH (10% solution): ~6.0–8.0
Density: ~0.90–1.00 g/cm³
Viscosity: Low to medium
Solubility: Fully miscible with water
Active Content: Typically 25–35% (commercial solutions)

Melting Point: 132-133°C
pH: 6.0-8.0
Solubility: Soluble in water
Viscosity: Moderate to high

Molecular Weight: 229.40 g/mol
XLogP3-AA: 5.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 11
Exact Mass: 229.240564612 Da
Monoisotopic Mass: 229.240564612 Da
Topological Polar Surface Area: 18.1 Ų
Heavy Atom Count: 16
Complexity: 146
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes