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LAURYL LACTATE

Synonyms: dodecyl 2-hydroxypropanoate; 2-hydroxypropionic acid dodecyl ester; dodecyl 2-hydroxypropionate; Eutanol G; lauryl lactate; LAURYL LACTATE; Cyclochem LVL; Dodecyl lactate; Dodecyl 2-hydroxypropanoate

Lauryl Lactate is a highly purified alpha hydroxy acid (AHA) ester product. While occasionally used as a surfactant in an emulsion, typical applications for lauryl lactate include emolliency and penetration enhancement in topical formulations. It can also be used as a solubiliser for hydrophobic molecules.

CAS NO:6283-92-7

Synonyms:
dodecyl 2-hydroxypropanoate; 2-hydroxypropionic acid dodecyl ester; dodecyl 2-hydroxypropionate; Eutanol G; lauryl lactate; LAURYL LACTATE; Cyclochem LVL; Dodecyl lactate; Dodecyl 2-hydroxypropanoate; Ceraphyl 31; 6283-92-7; Crodamol LL; Lactic acid, dodecyl ester; Propanoic acid, 2-hydroxy-, dodecyl ester; NSC 7752; Propanoic acid,2-hydroxy-, dodecyl ester; Pelemol LL; EINECS 228-504-8; Chrystap HYL 98; AC1L2KVQ; Lactic Acid Dodecyl Ester; lauryl lactate, AldrichCPR; SCHEMBL33838; LACTIC ACID DODECYLESTER; CTK5B6301; NSC7752; QQQMUBLXDAFBRH-UHFFFAOYSA-N; NSC-7752; 2-Hydroxypropanoic Acid Dodecyl Ester; AKOS015950776; 2-Hydroxypropanoic acid, dodecyl ester; LAURİL LAKTAT; lauril laktat;CeraphylTM 31 ; EXCEPARL® LM-LC; Pelemol LL;Ceraphyl 31;Crodamol LL;Cyclochem LVL;Schercemol LL;Dodecyllactate;Chrystap HYL 98;Lactic Acid Dodecyl Ester;Lactic acid, dodecyl ester (7CI);2-hydroxypropionic acid dodecyl ester;dodecyl 2-hydroxypropionate;Eutanol G;lauryl lactate;LAURYL LACTATE;Cyclochem LVL;Dodecyl lactate;Dodecyl 2-hydroxypropanoate;Ceraphyl 31;6283-92-7;Crodamol LL;Lactic acid, dodecyl ester;Propanoic acid, 2-hydroxy-, dodecyl ester;NSC 7752;Propanoic acid,2-hydroxy-, dodecyl ester;Pelemol LL;EINECS 228-504-8;Chrystap HYL 98;AC1L2KVQ;Lactic Acid Dodecyl Ester;lauryl lactate, AldrichCPR;SCHEMBL33838;LACTIC ACID DODECYLESTER;CTK5B6301;NSC7752;QQQMUBLXDAFBRH-UHFFFAOYSA-N;NSC-7752;2-Hydroxypropanoic Acid Dodecyl Ester;AKOS015950776;2-Hydroxypropanoic acid, dodecyl ester;129086-71-1;AN-21933;LP007872;AB1004645;FT-0670699;10.14272/QQQMUBLXDAFBRH-UHFFFAOYSA-N;doi:10.14272/QQQMUBLXDAFBRH-UHFFFAOYSA-N;143894-91-1;ceraphyl 31;crodamol LL;cyclochem LVL;dermol LL;dodecyl 2-hydroxypropanoate;dodecyl lactate;2-hydroxy-propanoic acid dodecyl ester;2-hydroxypropanoic acid dodecyl ester;2-hydroxypropanoic acid, dodecyl ester;lactic acid dodecyl ester;lactic acid, dodecyl ester;propanoic acid, 2-hydroxy-, dodecyl ester;schercemol LL ester;NSC 7752;Pelemol LL;Ceraphyl 31;Crodamol LL;Cyclochem LVL;Schercemol LL;Dodecyllactate;Chrystap HYL 98;Lactic Acid Dodecyl Ester;Lactic acid, dodecyl ester (7CI);CETYL LACTATE ;Nomilin TRI(N-OCTYLDECYL)ACETYL CITRATE LACTIC ACID ;TETRADECYL ESTER PROTOVERATRINE B STEARYL TARTRATE DEACETYLNOMILIN Paclitaxel PROTOVERATRINE A Docetaxel GYPSOGENIN-3-GLUCORONIDE RUTAEVIN Sitofibrate STEARYL CITRATE MONO PACLITAXEL-[BENZOATE RING-UL-14C] ;PROTOVERATRINE A+B Limonin 3BETA-HYDROXY-5-ANDROSTEN-17-ONE 3-GLUCURONIDE;2-hydroxy-propanoicacidodecylester; 2-hydroxy-propionicaciddodecylester Dodecyllactate Propanoicacid,2-hydroxy-,dodecylester 6283-92-7 2-hydroxy-propanoic acid dodecyl ester ;Lactic Acid Dodecyl Ester Ceraphyl ;31 Chrystap HYL 98 Crodamol LL Cyclochem LVL Lactic acid, dodecyl ester (7CI) NSC 7752 Pelemol LL Schercemol LL Aliphatics Fatty Acid Derivatives & Lipids Glycerols;2-hydroxy-propanoicacidodecylester;2-hydroxy-propionicaciddodecylester;Dodecyllactate;Propanoicacid,2-hydroxy-,dodecylester;2-hydroxy-propanoic acid dodecyl ester;Lactic Acid Dodecyl Ester;Ceraphyl 31;Chrystap HYL 98;EXCEPARL® LM-LC;2-hydroxy-propanoicacidodecylester;2-hydroxy-propionicaciddodecylester;Dodecyllactate;Propanoicacid,2-hydroxy-,dodecylester;2-hydroxy-propanoic acid dodecyl ester;Lactic Acid Dodecyl Ester;2-Hydroxypropanoic Acid Dodecyl Ester; Ceraphyl 31; Chrystap HYL 98; Crodamol LL; Cyclochem LVL; Dodecyl Lactate; Lauryl Lactate; NSC 7752; Pelemol LL;;Lauryl lactate;2-Hydroxypropanoate de dodécyle [French] [ACD/IUPAC Name];Dodecyl 2-hydroxypropanoate [ACD/IUPAC Name];Dodecyl-2-hydroxypropanoat [German] [ACD/IUPAC Name];Lactic acid, dodecyl ester;Propanoic acid, 2-hydroxy-, dodecyl ester [ACD/Index Name];UNII:G5SU0BFK7O;129086-71-1 [RN];143894-91-1 [RN];228-504-8 [EINECS];2-Hydroxypropanoic acid dodecyl ester;2-Hydroxy-propanoic acid dodecyl ester;2-Hydroxypropanoic acid, dodecyl ester;6283-92-7 [RN];Ceraphyl 31;Chrystap HYL 98;Crodamol LL;Cyclochem LVL;dodecyl lactate;Eutanol G;Lactic Acid Dodecyl Ester;LACTIC ACID DODECYLESTER;Lactic acid, dodecyl ester (7CI);Lauryllactate;Pelemol LL;Propanoic acid,2-hydroxy-, dodecyl ester;Schercemol LL;L3; Propanoic acid, 2-hydroxy 2-(C10-16-alkyloxy)-1-methyl-2-oxoethyl ester; Propanoic acid, 2-hydroxy-, 2-(C10-16-alkyloxy)-1-methyl-2-oxoethyl ester; Propanoic Acid, 2-Hydroxy-, 2-(C10-16-Alkyloxy)-1-Methyl-2-Oxoethyl Ester;Dodecyl 2-hydroxypropanoate; 2-Hydroxypropanoic acid, dodecyl ester; Lauryl lactate; Propanoic acid, 2-hydroxy-, dodecyl ester; Ceraphyl 31; Crodamol LL; Cyclochem LVL; Dodecyl lactate; Lactic acid, dodecyl ester; NSC 7752; UNII-G5SU0BFK7O;Cyclochem LVL, Dodecyl lactate, Ceraphyl 31, Crodamol LL, Eutanol G, LAURYL LACTATE, Lactic acid, dodecyl ester, Dodecyl 2-hydroxypropanoate, NSC7752, CID22692, NSC 7752, EINECS 228-504-8, 2-Hydroxypropanoic acid, dodecyl ester, Propanoic acid, 2-hydroxy-, dodecyl ester, 6283-92-7, 129086-71-1, 143894-91-1; lauril laktat; lauryl lactate

LAURYL LACTATE 

LAURYL LACTATE
LAURYL LACTATE is classified as :
Emollient
Skin conditioning
CAS Number    6283-92-7
EINECS/ELINCS No:    228-504-8
COSING REF No:    77074
Chem/IUPAC Name:    Dodecyl lactate


Lauryl Lactate
Chemical Description
Lauryl lactate

Product Description
Super Refined Lauryl Lactate is a highly purified alpha hydroxy acid (AHA) ester product. While occasionally used as a surfactant in an emulsion, typical applications for lauryl lactate include emolliency and penetration enhancement in topical formulations. It can also be used as a solubiliser for hydrophobic molecules, such as poorly water soluble active pharmaceutical ingredients (APIs) while still remaining water soluble. It is a naturally derived, mild, and virtually odourless nonionic surfactant.

Chemical Group
Ester

Market Application
Dermatology

Functions
Emollient
Emulsifier
Excipient
Humectant
Penetration enhancer

Administration Route
Topical

Lauryl Lactate
What Is Lauryl Lactate?
Glycolic Acid and Lactic Acid are naturally occuring organic acids also known as Alpha Hydroxy Acids or AHAs. The salts of Glycolic Acid (Ammonium Glycolate, Sodium Glycolate), the salts of Lactic Acid (Ammonium Lactate, Calcium Lactate, Potassiu Lactate, Sodium Lactate, TEA-Lactate) and the esters of Lactic Acid (Methyl Lactate, Ethyl Lactate, Butyl Lactate, Lauryl Lactate, Myristyl Lactate, Cetyl Lactate) may also be used in cosmetics and personal care products. In cosmetics and personal care products, these ingredients are used in the formulation of moisturizers, cleansing products, and other skin care products, as well as in makeup, shampoos, hair dyes and colors and other hair care products.

Why is Lauryl Lactate used in cosmetics and personal care products?
The following functions have been reported for Glycolic Acid, Lactic Acid and their salts and esters.

Buffering agent - Ammonium Lactate, Potassium Lactate, Sodium Lactate
Cosmetic astringent - Calcium Lactate
Exfoliant - Glycolic Acid, Lactic Acid, Ammonium Glycolate, Ammonium Lactate, Calcium Lactate, Potassium Lactate, Sodium Lactate
Humectant - Lactic Acid
pH adjuster - Glycolic Acid, Lactic Acid, Ammonium Glycolate, Sodium Glycolate
Skin conditioning agent - emollient - Lauryl Lactate, Myristyl Lactate, Cetyl Lactate
Skin conditioning agent - humectant - Lactic Acid, Ammonium Lactate, Potassium Lactate, Sodium Lactate, TEA-Lactate
Skin conditioning agent - miscellaneous - Lactic Acid
Solvent - Methyl Lactate, Ethyl Lactate, Butyl Lactate
Scientific Facts: 
Glycolic Acid and Lactic Acid are alpha hydroxy acids (AHAs). They may be either naturally occurring or synthetic. They are often found in products intended to improve the overall look and feel of the skin. Glycolic acid is the most widely used of out of the group and is usually manufactured from sugar cane. Lactic acid, derived primarily from milk and its origins can be traced back to Cleopatra, who purportedly used sour milk on her skin.

Molecular Weight of Lauryl Lactate    258.4 g/mol    Computed by PubChem 2.1 (PubChem release 2019.06.18)
XLogP3-AA of Lauryl Lactate    5.4    Computed by XLogP3 3.0 (PubChem release 2019.06.18)
Hydrogen Bond Donor Count of Lauryl Lactate    1    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Hydrogen Bond Acceptor Count of Lauryl Lactate    3    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Rotatable Bond Count of Lauryl Lactate    13    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Exact Mass of Lauryl Lactate    258.219495 g/mol    Computed by PubChem 2.1 (PubChem release 2019.06.18)
Monoisotopic Mass of Lauryl Lactate    258.219495 g/mol    Computed by PubChem 2.1 (PubChem release 2019.06.18)
Topological Polar Surface Area of Lauryl Lactate    46.5 Ų    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Heavy Atom Count of Lauryl Lactate    18    Computed by PubChem
Formal Charge of Lauryl Lactate    0    Computed by PubChem
Complexity of Lauryl Lactate    192    Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Isotope Atom Count of Lauryl Lactate    0    Computed by PubChem
Defined Atom Stereocenter Count of Lauryl Lactate    0    Computed by PubChem
Undefined Atom Stereocenter Count of Lauryl Lactate    1    Computed by PubChem
Defined Bond Stereocenter Count of Lauryl Lactate    0    Computed by PubChem
Undefined Bond Stereocenter Count of Lauryl Lactate    0    Computed by PubChem
Covalently-Bonded Unit Count of Lauryl Lactate    1    Computed by PubChem
Compound  of Lauryl Lactate Is Canonicalized    Yes

EC NO:228-504-8

Molecular Formula
C15H30O3

IUPAC Name
dodecyl 2-hydroxypropanoate

Lauryl Lactate is a naturally occurring acid known as an Alpha Hydroxy Acid (AHA) found in beauty products and cosmetics functioning as an emollient, skin conditioning agent, and exfoliant. It is also infrequently used to impart fragrance in some products.

Function of Lauryl Lactate

Lauryl Lactate is a naturally occurring acid known as an Alpha Hydroxy Acid (AHA) found in beauty products and cosmetics functioning as an emollient, skin conditioning agent, and exfoliant. It is also infrequently used to impart fragrance in some products.

Because Lauryl Lactate is so versatile, it is seen as an ingredient in a variety of beauty products and cosmetics, including: moisturizers, exfoliants, cleansers, body lotions, makeup, shampoos, hair dyes, and conditioners.

What Is Lauryl Lactate
Glycolic Acid and Lactic Acid are naturally occuring organic acids also known as Alpha Hydroxy Acids or AHAs. The salts of Glycolic Acid (Ammonium Glycolate, Sodium Glycolate), the salts of Lactic Acid (Ammonium Lactate, Calcium Lactate, Potassiu Lactate, Sodium Lactate, TEA-Lactate) and the esters of Lactic Acid (Methyl Lactate, Ethyl Lactate, Butyl Lactate, Lauryl Lactate, Myristyl Lactate, Cetyl Lactate) may also be used in cosmetics and personal care products. In cosmetics and personal care products, these ingredients are used in the formulation of moisturizers, cleansing products, and other skin care products, as well as in makeup, shampoos, hair dyes and colors and other hair care products.

Lauryl Lactate is used to reduce tackiness and greasiness of other components, such as petrolatum. It imparts non-oily lubricity to hydro-alcoholic products. It is easy to emulsify and best at neutral pH. This product provides viscosity building & lather creaminess to shampoos and body washes.

Lauryl Lactate is a naturally occurring acid known as an Alpha Hydroxy Acid (AHA) found in beauty products and cosmetics functioning as an emollient, skin conditioning agent, and exfoliant. It is also infrequently used to impart fragrance in some products.

APPLICATION FIELD
Bath and shower products
Hair care
Skin care

DESCRIPTION
Natural Liquid thickener even for EO- & SLES-Free formulations
PEG-, Nitrogen- & Salt-Free product
Biodegradable, Mild and Safe product
Viscosity and pH Stabiliser
Rheology Modifier

PROPERTIES
Thickener

PHYSICAL PROPERTIES OF LAURYL LACTATE
Appearance:    pale yellow to yellow clear liquid (est)
Assay:    88.00 to 100.00 % 
Food Chemicals Codex Listed:    No
Specific Gravity:    0.91000 to 0.92200 @ 25.00 °C.
Pounds per Gallon - (est).:    7.572 to 7.672
Refractive Index:    1.44170 to 1.44560 @ 25.00 °C.
Boiling Point:    303.00 to 304.00 °C. @ 760.00 mm Hg
Acid Value:    5.00 max. KOH/g
Saponification Value:    210.00 to 225.00
Vapor Pressure:    0.000080 mm/Hg @ 25.00 °C. (est)
Flash Point:    271.00 °F. TCC ( 132.78 °C. )

 Density:    0.9±0.1 g/cm3
Boiling Point:    304.1±10.0 °C at 760 mmHg
Vapour Pressure:    0.0±1.4 mmHg at 25°C
Enthalpy of Vaporization:    63.1±6.0 kJ/mol
Flash Point:    133.1±7.0 °C
Index of Refraction:    1.452
Molar Refractivity:    74.8±0.3 cm3
#H bond acceptors:    3
#H bond donors:    1
#Freely Rotating Bonds:    13
#Rule of 5 Violations:    1
ACD/LogP:    5.13
ACD/LogD (pH 5.5):    5.32
ACD/BCF (pH 5.5):    6562.17
ACD/KOC (pH 5.5):    18785.97
ACD/LogD (pH 7.4):    5.32
ACD/BCF (pH 7.4):    6562.15
ACD/KOC (pH 7.4):    18785.93
Polar Surface Area:    47 Å2
Polarizability:    29.7±0.5 10-24cm3
Surface Tension:    33.5±3.0 dyne/cm
Molar Volume:    277.5±3.0 cm3

Functions:

Lauryl Lactate is a naturally occurring acid known as an Alpha Hydroxy Acid (AHA) found in beauty products and cosmetics functioning as an emollient, skin conditioning agent, and exfoliant. It is also infrequently used to impart fragrance in some products (Source).

Because Lauryl Lactate is so versatile, it is seen as an ingredient in a variety of beauty products and cosmetics, including: moisturizers, exfoliants, cleansers, body lotions, makeup, shampoos, hair dyes, and conditioners.

Safety Measures/Side Effects:

The CIR has approved Lauryl Lactate for use in cosmetics, but only in concentrates less than 10%, and only with a pH level of 3.5 or greater (Source).

In addition, it is important to note that while Lauryl Lactate itself is not considered carcinogenic, because it is classified as an AHA and sometimes used as an exfoliant, it is thought to increase the risk of cancer because it exposes the upper layers of the dermis to UV rays. Therefore, Lauryl Lactate should always be used with a sunscreen to negate this increase risk

The FDA has approved Lauryl Lactate as GRAS (Generally Recognized as Safe) when used as a food additive.

 

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