Linoleic Acid is a polyunsaturated omega-6 fatty acid essential for human health, commonly found in vegetable oils, seeds, nuts, and certain animal fats.
Linoleic Acid plays a vital role in maintaining the integrity of cell membranes, supporting skin barrier function, and regulating inflammatory responses.
Linoleic Acid is widely used in food, cosmetics, pharmaceuticals, and industrial formulations due to its biological significance and versatile properties.
CAS Number: 60-33-3
EC Number: 200-470-9
Molecular Formula: C18H32O2
Molecular Weight: 280.45 g/mol
Synonyms: 9,12-Octadecadienoic Acid, cis,cis-Linoleic Acid, LA, Omega-6 Fatty Acid, Essential Fatty Acid, (Z,Z)-9,12-Octadecadienoic Acid, Linolic Acid, Vitamin F Component, Unsaturated Fatty Acid, Plant-Based Omega-6, Linoleic Acid, (9Z,12Z)-Octadeca-9,12-dienoic acid, cis,cis-9,12-Octadecadienoic acid, C18:2 (n−6), 18:2 n‑6 fatty acid, LA, Omega‑6 linoleic acid, n‑6 polyunsaturated fatty acid, PUFA linoleic acid, Unsaturated C18 fatty acid, Telfairic Acid, 9,12-Linoleic acid, 9,12-Octadecadienoic Acid, Vegetable oil fatty acid, Essential linoleic acid, Dietary linoleic acid, Linoleate (acid form), 9Z,12Z-linoleic acid, Linoleic fatty acid, Linolic acid (alt.), Cis‑linoleic acid, Octadecadienoic acid cis‑9,12, Fatty acid 18:2, Polyunsaturated omega‑6 acid, Linolic fatty acid, 18:2(PUFA) acid, Plant-derived linoleic acid, Seed oil acid, Corn oil LA, Safflower oil LA, Sunflower oil LA, Evening primrose LA
APPLICATIONS
Linoleic Acid is used in dietary supplements to support cardiovascular health and essential fatty acid intake.
Linoleic Acid is included in nutritional formulations to maintain balanced lipid profiles.
Linoleic Acid is applied in infant formula and enteral nutrition products for healthy growth.
Linoleic Acid is utilized in functional foods such as fortified cereals, bars, and dairy alternatives.
Linoleic Acid is included in edible oils like sunflower, safflower, and soybean oil for its health benefits.
Linoleic Acid is used in energy drinks and sports nutrition blends to support metabolism.
Linoleic Acid is a key ingredient in skincare products for improving hydration and repairing the skin barrier.
Linoleic Acid is used in moisturizers, serums, and face oils to soothe inflammation and reduce acne.
Linoleic Acid is incorporated into anti-aging and brightening products for its cell-regenerating effects.
Linoleic Acid is found in hair care products to restore shine, reduce dryness, and strengthen strands.
Linoleic Acid is used in scalp treatments and conditioners to support healthy hair growth.
Linoleic Acid is added to beard and eyelash serums for nourishment and conditioning.
Linoleic Acid is included in pharmaceutical formulations to manage skin disorders such as eczema and psoriasis.
Linoleic Acid is studied for its role in wound healing and inflammatory disease treatment.
Linoleic Acid is used in medical creams and ointments to improve skin elasticity and reduce transepidermal water loss.
Linoleic Acid is used in pet foods and veterinary supplements to support skin, coat, and overall wellness in animals.
Linoleic Acid is included in livestock feed to improve meat quality and reproductive health.
Linoleic Acid is used in aquaculture to enrich feed with essential fatty acids for optimal fish health.
Linoleic Acid is utilized in biodegradable lubricants and esters for sustainable industrial applications.
Linoleic Acid is used in the production of alkyd resins, coatings, and plasticizers.
Linoleic Acid is included in green solvents and cleaning products as a renewable component.
Linoleic Acid is used in skincare products to maintain the skin’s moisture barrier.
Linoleic Acid is applied in facial oils to help treat acne-prone skin.
Linoleic Acid is incorporated into moisturizers for its anti-inflammatory properties.
Linoleic Acid is used in anti-aging serums to reduce the appearance of fine lines.
Linoleic Acid is included in creams for dry or irritated skin.
Linoleic Acid is added to body lotions to improve skin smoothness and hydration.
Linoleic Acid is used in scalp treatments to combat dryness and flakiness.
Linoleic Acid is included in hair masks to improve shine and strength.
Linoleic Acid is applied in shampoos to support healthy hair follicles.
Linoleic Acid is used in conditioners to nourish and moisturize damaged hair.
Linoleic Acid is incorporated into lip balms for its emollient properties.
Linoleic Acid is used in makeup removers to dissolve sebum and impurities.
Linoleic Acid is included in sunscreen formulations to prevent oxidative damage.
Linoleic Acid is applied in massage oils for skin hydration and flexibility.
Linoleic Acid is used in cuticle oils to restore nail bed moisture.
Linoleic Acid is included in beard care products to soften coarse facial hair.
Linoleic Acid is used in foot creams to heal cracked skin.
Linoleic Acid is applied in baby care products for its gentle moisturizing effects.
Linoleic Acid is included in eczema creams to relieve itch and inflammation.
Linoleic Acid is used in body butters to reinforce the skin's lipid barrier.
Linoleic Acid is incorporated into tanning lotions to prevent dryness from UV exposure.
Linoleic Acid is used in eye creams to improve skin elasticity around the eyes.
Linoleic Acid is included in overnight masks for overnight repair and moisture retention.
Linoleic Acid is used in pharmaceutical ointments to promote wound healing.
Linoleic Acid is applied in stretch mark creams to support collagen production.
Linoleic Acid is included in acne creams for its sebum-regulating abilities.
Linoleic Acid is used in anti-pollution skincare products to counteract environmental stress.
Linoleic Acid is incorporated into cleansing balms for its ability to dissolve makeup and oil.
Linoleic Acid is used in anti-redness treatments for its calming effect on sensitive skin.
Linoleic Acid is added to dietary supplements for cardiovascular health.
Linoleic Acid is used in fortified foods to promote healthy cholesterol levels.
Linoleic Acid is included in pet nutrition to improve skin and coat condition.
Linoleic Acid is used in poultry feed to enhance egg quality.
Linoleic Acid is incorporated into nutritional beverages for essential fatty acid content.
Linoleic Acid is used in infant formulas to support early brain and eye development.
Linoleic Acid is added to health bars as a functional lipid source.
Linoleic Acid is used in nutricosmetics for beauty-from-within supplements.
Linoleic Acid is applied in clinical nutrition formulas for malnourished patients.
Linoleic Acid is included in vegan capsules for skin and joint health.
Linoleic Acid is used in emulsifiers in food and personal care formulations.
Linoleic Acid is incorporated into cooking oils for its unsaturated fat profile.
Linoleic Acid is used in dairy substitutes to balance fatty acid content.
Linoleic Acid is included in margarines as part of a heart-healthy fat blend.
Linoleic Acid is used in plant-based meat products for juiciness and mouthfeel.
Linoleic Acid is applied in animal feed to improve growth and energy utilization.
Linoleic Acid is used in agricultural biostimulants to enhance plant metabolism.
Linoleic Acid is included in capsule-based supplements for inflammatory conditions.
Linoleic Acid is used in antioxidant formulations with vitamins A and E.
Linoleic Acid is added to cosmetic emulsions for its stability and skin affinity.
Linoleic Acid is used in pharmaceutical excipients for dermal drug delivery.
DESCRIPTION
Linoleic Acid is a colorless to pale yellow oily liquid with a mild, slightly fatty odor.
Linoleic Acid contains two cis-double bonds at carbon 9 and carbon 12, classifying it as an omega-6 polyunsaturated fatty acid.
Linoleic Acid is not synthesized by the human body and must be obtained from dietary sources.
Linoleic Acid is primarily extracted from vegetable oils such as sunflower, safflower, soybean, and corn oils.
Linoleic Acid is susceptible to oxidation and is often stabilized with antioxidants like tocopherols.
Linoleic Acid is sensitive to heat and light, requiring careful storage to maintain stability.
Linoleic Acid is a component of ceramides and lipids in the epidermis, playing a role in maintaining skin moisture and integrity.
Linoleic Acid is metabolized into arachidonic acid and other bioactive lipid mediators involved in inflammation and immunity.
Linoleic Acid is approved for use in food, pharmaceutical, and cosmetic products by global regulatory authorities.
Linoleic Acid supports cardiovascular health by helping to manage cholesterol levels.
Linoleic Acid is often deficient in acne-prone skin, which makes topical application beneficial.
Linoleic Acid exhibits anti-inflammatory properties that are beneficial in skincare and nutrition.
Linoleic Acid contributes to the fluidity and function of cell membranes.
Linoleic Acid is widely used in both the cosmetic and nutraceutical industries due to its multifunctionality.
PROPERTIES
Chemical Name: Linoleic Acid
CAS Number: 60-33-3
EC Number: 200-470-9
Molecular Formula: C18H32O2
Molecular Weight: 280.45 g/mol
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild fatty odor
Melting Point: -5°C to -11°C
Boiling Point: ~230°C (decomposes)
Flash Point: >200°C
Density: ~0.91 g/cm³ at 20°C
Solubility: Insoluble in water; soluble in alcohol, ether, and other organic solvents
Acid Value: Typically ~190–200 mg KOH/g
Iodine Value: ~170–180
Storage: Store in a cool, dry, and dark place, preferably under nitrogen
Stability: Sensitive to oxidation; stabilize with antioxidants
FIRST AID
Inhalation:
Move to fresh air if irritation occurs from vapor exposure.
Seek medical attention if symptoms persist.
Skin Contact:
Wash affected area with soap and water.
Generally non-irritating and skin-friendly.
Eye Contact:
Flush eyes with water for at least 15 minutes.
Consult a physician if irritation continues.
Ingestion:
Non-toxic in food-grade form.
Rinse mouth and drink water if consumed in excess.
Seek medical attention if adverse symptoms occur.
Note to Physicians:
No specific antidote.
Supportive and symptomatic treatment recommended.
HANDLING AND STORAGE
Handling:
Use protective gloves and eyewear in industrial settings.
Minimize exposure to air and light to prevent rancidity.
Handle with care in cosmetic and food processing environments.
Storage:
Store in tightly closed containers in a cool, dry place.
Use amber bottles or inert gas flushing for long-term stability.
Keep away from oxidizing agents and direct sunlight.
Spill Procedures:
Wipe or absorb with inert material such as sand or vermiculite.
Clean surface thoroughly to prevent slipping hazard.
Dispose according to local environmental regulations.
Disposal:
Dispose of in accordance with local and national regulations.
Small quantities may be composted or used in animal feed if uncontaminated.