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Lonzabac 12.30, also called N,N-bis(3-aminopropyl)dodecylamine and laurylamine dipropylenediamine, is dodecylamine substituted with 2 propylamine units.
Lonzabac 12.30 is a non-ionic surfactant, antimicrobial agent, preservative, emulsifying agent, dispersing agent, corrosion inhibitor and an anti-static agent used in hair products.
Lonzabac 12.30 is an active material with broad spectrum activity against both gram positive and gram negative bacteria.
CAS Number: 2372-82-9
Molecular Formula: C18H41N3
Molecular Weight: 299.54
EINECS Number: 219-145-8
Synonyms: 2372-82-9, N-(3-Aminopropyl)-N-dodecylpropane-1,3-diamine, Laurylamine dipropylenediamine, N1-(3-aminopropyl)-N1-dodecylpropane-1,3-diamine, N,N-bis(3-aminopropyl)dodecylamine, Bis(aminopropyl)laurylamine, 1,3-Propanediamine,N1-(3-aminopropyl)-N1-dodecyl-, 1,3-Propanediamine, N-(3-aminopropyl)-N-dodecyl-, EINECS 219-145-8, PCJ6308JUE, N-(3-Aminopropyl)-N-dodecyl-1,3-propanediamine, EC 219-145-8, N'-(3-aminopropyl)-N'-dodecylpropane-1,3-diamine, BIS(3-AMINOPROPYL)(DODECYL)AMINE, LONZABAC-12.100, DTXSID3041243, 1,3-Propanediamine, N-(3-aminopropyl)-N-dodecyl, 1,3-Propanediamine, N1-(3-aminopropyl)-N1-dodecyl-, LAURYLAMINE DIPROPYLENEDIAMINE [WHO-DD], AMINOPROPYL)-N-DODECYL-1,3-PROPANEDIAMINE, N-(3-, UNII-PCJ6308JUE, N-?(3-?Aminopropyl)?-?n-?dodecylpropane-?1,?3-?diamine, bis(3-aminopropyl)dodecylamine, N-?(3-?Aminopropyl)?-?n-?dodecylpropane-?1,?3-?diamine (>80%), Lonzabec-12, MFCD04112927, NN-bis-APDA, SCHEMBL24179, bis-(3-aminopropyl)-laurylamine, DTXCID1021243, BCP23852, AKOS015894470, FA76100, FS-6129, DA-43112, LAURYLAMINE DIPROPYLENEDIAMINE [INCI], NS00003278, EN300-265848, G78676, N'-(3-aminopropyl)-N'-dodecyl-propane-1,3-diamine, Q27286479, F1905-6424, Laurylaminedipropylenediamine, N,N-Bis(3-aminopropyl)laurylamine, Bis(aminopropyl)laurylamine;1,3-Propanediamine, N-(3-aminopropyl)-N-dodecyl-;LONZABAC12.100;N-3-AMINOPROPYL-N-DODECYL-1,3-PROPANEDIAMINE;N-(3-Aminopropyl)-N-dodecylpropan-1,3-diamin;3-Propanediamine, N-(3-aminopropyl)-N-dodecyl-1;N,N-Bis-(3-aminopropyl)-laurylamine;methylenediamine
Lonzabac 12.30 maintains its high efficacy in the presence of heavy organic soiling while also having good surfactant properties.
This material is for formulation into antimicrobial/disinfectant product for use on hard nonporous surfaces.
Lonzabac 12.30 is a broad spectrum biocide.
Lonzabac 12.30 maintains high efficacy even in presence of heavy organic soiling.
Lonzabac 12.30 has good surfactant properties and is compatible with selected anionic surfactants.
Lonzabac 12.30 can be used as a disinfectant and preservative in industrial applications where microbial control is important.
Its broad spectrum antimicrobial properties make it suitable for preventing microbial growth in complex formulations without compromising efficacy.
Lonzabac 12.30, chemically known as N,N-Bis(3-aminopropyl)dodecylamine, is a broad-spectrum biocidal agent effective against both gram-positive and gram-negative bacteria.
Lonzabac 12.30 maintains high efficacy even in the presence of heavy organic soiling, such as blood and protein.
Additionally, Lonzabac 12.30 is active against enveloped viruses like Hepatitis B and HIV, and various fungi.
Beyond its antimicrobial properties, it functions as a surfactant and wetting agent, offering good surface-active characteristics.
Its compatibility with selected anionic surfactants enhances its versatility in formulation.
Due to its low toxicity and high biodegradability, Lonzabac 12.30 is suitable for applications in hospital disinfectants, food industry sanitizers, industrial kitchens, surgical instrument disinfection, and as a bactericidal component in textile treatments.
Lonzabac 12.30 is an active material with broad spectrum activity against both gram positive and gram negative bacteria.
Lonzabac 12.30 maintains its high efficacy in the presence of heavy organic soiling while also having good surfactant properties.
Lonzabac 12.30 is for formulation into antimicrobial/disinfectant product for use on hard nonporous surfaces.
Lonzabac 12.30 has been found to have a wide range of applications in scientific research.
Lonzabac 12.30 has been used as a surfactant for the synthesis and purification of proteins, liposomes, and other biomolecules.
Lonzabac 12.30 is also used in drug delivery systems, as it can be used to modify the surface of liposomes to increase their stability and enhance their drug delivery efficiency.
Additionally, Lonzabac 12.30 has been used as a detergent for various industrial processes, such as emulsification, extraction, and separation.
Lonzabac 12.30 has been found to act as an amphiphilic surfactant, meaning that it has both hydrophilic and hydrophobic regions.
This allows it to form micelles, which are aggregates of molecules that are surrounded by a hydrophilic shell and an inner hydrophobic core.
These micelles can then interact with the surface of biomolecules, such as proteins, and modify their surface properties.
This can be used to increase the solubility of proteins, as well as to increase their stability and improve their drug delivery efficiency.
Lonzabac 12.30 is a highly effective antimicrobial agent that belongs to the class of amphoteric surfactants, specifically designed for use in industrial and institutional cleaning, disinfection, and hygiene applications.
Lonzabac 12.30 is widely used due to its broad-spectrum activity against bacteria, fungi, and viruses, making it an essential component in formulations for disinfectants, sanitizers, and cleaning products.
Effective against both Gram-positive and Gram-negative bacteria, including resistant strains like Pseudomonas aeruginosa and Staphylococcus aureus.
Shows strong fungicidal properties against molds and yeasts, ensuring surfaces remain free of fungal contamination.
Active against enveloped viruses, including HIV, Hepatitis B, and Coronaviruses, making it valuable in medical and hygiene-related applications.
Unlike many disinfectants that lose potency in the presence of organic material (e.g., blood, protein residues), Lonzabac 12.30 remains effective even in soiled environments.
Quickly kills bacteria, fungi, and viruses upon contact, reducing the risk of infection.
Acts as both a disinfectant and detergent, helping to remove biofilms, grease, and dirt.
Safe for use on metals, plastics, and textiles, making it ideal for medical instruments and food processing equipment.
Highly biodegradable and low toxicity, making it safer for both users and the environment.
Unlike many disinfectants that lose effectiveness in the presence of blood, proteins, or fats, Lonzabac 12.30 retains its antimicrobial potency even in heavily soiled environments.
Enhances cleaning efficiency by reducing surface tension, allowing it to penetrate biofilms and organic debris.
Compatible with certain anionic surfactants, which improves its formulation flexibility in multi-purpose disinfectants.
Environmentally friendly, with a high biodegradability profile, making it suitable for applications where environmental safety is a concern.
Exhibits low toxicity to humans and animals, provided it is used according to recommended guidelines.
Healthcare Sector: Used in hospital disinfectants, surgical instrument cleaning solutions, and surface sanitizers.
Incorporated in food-safe sanitizers for industrial kitchens, dairy processing plants, and beverage manufacturing.
Industrial Hygiene: Used in water treatment, textile treatments, and as a preservative in paint, coatings, and adhesives to prevent microbial contamination.
Lonzabac 12.30 is a biocidal surfactant with a wide range of applications in disinfection, industrial cleaning, and antimicrobial formulations.
It is commonly used in healthcare, food processing, industrial hygiene, and water treatment due to its broad-spectrum antimicrobial properties and high stability in challenging conditions.
Lonzabac 12.30 disrupts the structure and function of microbial cell membranes through multiple biochemical interactions:
Penetration into the lipid bilayer of bacteria, fungi, and enveloped viruses.
Destabilization of membrane integrity, causing leakage of essential cellular contents.
Inhibition of enzyme activity and disruption of protein synthesis, leading to microbial death.
Boiling point: 182-184 °C(Press: 1 Torr)
Density: 0.880
vapor pressure: 0Pa at 25℃
solubility: 560g/L in organic solvents at 20 ℃
form: Oil
pka: 10.46±0.10(Predicted)
color: Colourless
Viscosity: 24.18mm2/s
Water Solubility: 190g/L at 20℃
InChI: InChI=1S/C18H41N3/c1-2-3-4-5-6-7-8-9-10-11-16-21(17-12-14-19)18-13-15-20/h2-20H2,1H3
InChIKey: NYNKJVPRTLBJNQ-UHFFFAOYSA-N
SMILES: C(N(CCCN)CCCCCCCCCCCC)CCN
LogP: 0.34 at 20℃
Lonzabac 12.30 has been found to be non-toxic and biodegradable, making it suitable for use in various scientific applications.
Furthermore, Lonzabac 12 has been found to have no significant effect on the biochemical and physiological processes of cells.
This makes Lonzabac 12 a safe and reliable surfactant for use in various scientific applications.
One of the major advantages of Lonzabac 12 is its low toxicity and biodegradability.
This makes Lonzabac 12 a safe and reliable surfactant for use in various scientific applications.
Additionally, Lonzabac 12 has been found to be highly soluble in water, which makes it easy to use in laboratory experiments.
However, Lonzabac 12 has been found to be less effective in some applications, such as the synthesis and purification of proteins, when compared to other surfactants.
This alkylamine is contained in detergent-disinfectants solutions for medical instruments.
Lonzabac 12.30 Antimicrobial is a broad-spectrum biocidal active ingredient with good surfactant properties and is compatible with anionic surfactants.
Lonzabac 12 is effective against both gram-positive and gram-negative bacteria as well as Mycobacterium terrae and Mycobacterium avium.
Lonzabac 12 Antimicrobial maintains high efficacy even at low temperatures and in the presence of heavy organic soil, such as blood and protein, and is also effective against enveloped viruses such as Hepatitis-B (HBV).
Lonzabac 12 is stable across a wide range of pH levels and is usable in formulations for a number of applications such as food processing, institutional, veterinary and medical areas.
Lonzabac 12 Antimicrobial is offered in two product forms, ~27% or ~91% aqueous solution: Lonzabac® 12.30 and Lonzabac® 12.100 respectively.
Lonzabac 12 Antimicrobial is being supported through the European Union Biocidal Products Regulation (BPR)1 Active Substance Review Program for Product.
Lonzabac 12.30 is often used in combination with quaternary ammonium compounds (quats) or chlorine-based disinfectants to enhance its antimicrobial spectrum.
It remains stable over a wide pH range, making it adaptable for different cleaning and disinfecting formulations.
Lonzabac 12.30 is chemically known as N,N-Bis(3-aminopropyl)dodecylamine, an amphoteric surfactant with strong antimicrobial capabilities.
Its molecular structure consists of a long hydrophobic alkyl chain (dodecyl group) attached to a hydrophilic amine-based head group, allowing it to interact with microbial cell membranes and cause cell lysis.
Uses Of Lonzabac 12.30:
Lonzabac 12.30 is used as disinfectant for food processing industry, institutions, hospitals (surfaces and instruments)..
Lonzabac 12.30 is a key component in industrial cleaning solutions, providing effective microbial control in factories, warehouses, office buildings, and public facilities.
It is often included in floor cleaners, restroom disinfectants, and air disinfectant sprays, ensuring that large-scale work environments remain free from disease-causing bacteria and fungi.
Lonzabac 12.30s ability to act as a wetting agent and surfactant makes it highly effective in breaking down grease, dirt, and organic residues, which is particularly useful in industrial settings where heavy contamination occurs.
It is also used in laundry disinfectants and textile treatments, ensuring that fabrics and uniforms remain free from microbial contamination, especially in hospitals, hotels, and commercial laundries.
Lonzabac 12.30 is used as disinfectant for food processing industry, institutions, hospitals (surfaces and instruments).N-?(3-?Aminopropyl)?-?n-?dodecylpropane-?1,?3-?diamine is a reactant used in the synthesis of gluconamide derivatives as cationic surfactants with antimicrobial properties.
Used in hospital-grade disinfectants for surfaces, floors, and high-touch areas.
Incorporated into surgical instrument cleaners to prevent microbial contamination.
Found in hand sanitizers and skin antiseptics due to its gentle yet effective antimicrobial properties.
Commonly used as a sanitizing agent for food-contact surfaces in industrial kitchens and food production lines.
Helps prevent bacterial contamination in dairy processing, breweries, and meatpacking plants.
Acts as a preservative in food packaging materials to extend shelf life.
Effective in cooling towers, industrial water systems, and wastewater treatment plants to prevent microbial growth.
Used in paints, coatings, and adhesives to prevent microbial degradation.
Functions as a bacteriostatic agent in textiles, preventing mold and mildew formation.
Due to its low toxicity and broad-spectrum antimicrobial activity, Lonzabac 12.30 is sometimes used in personal care products such as shampoos, liquid soaps, and skin cleansers to provide antibacterial and antifungal protection.
It helps to prevent microbial contamination in cosmetic formulations, ensuring that products remain safe for use over extended periods.
Lonzabac 12.30 is also used in oral hygiene products, such as mouthwashes and dental rinses, where it provides antibacterial protection against plaque-forming bacteria and oral infections.
One of the less obvious but highly beneficial uses of Lonzabac 12.30 is its role as a preservative in paints, coatings, and adhesives, where microbial contamination can lead to product degradation, discoloration, and foul odors.
In the paint and coatings industry, microbial growth in stored products can cause lumping, separation, and unpleasant smells, reducing the shelf life and overall quality of the final product.
By incorporating Lonzabac 12.30 into water-based paints, coatings, and sealants, manufacturers can prevent mold, bacteria, and yeast contamination, ensuring that their products remain stable for extended periods.
Similarly, in the adhesives and sealant industry, it helps to maintain product consistency and prevent bacterial degradation, which is especially important in construction, packaging, and consumer goods applications.
Lonzabac 12.30 is used in the textile and leather industries to provide antimicrobial protection against mold, mildew, and bacterial growth, which can damage fabrics, synthetic materials, and natural fibers.
Lonzabac 12.30 is incorporated into fabric treatments, antimicrobial coatings, and textile finishing solutions, ensuring that clothing, upholstery, and industrial fabrics remain resistant to microbial degradation even in humid environments.
Additionally, Lonzabac 12.30 is used in leather tanning and processing to prevent bacterial and fungal deterioration, which is particularly important in the production of high-quality leather goods, footwear, and furniture upholstery.
In the agriculture and livestock industries, maintaining hygiene in farms, poultry houses, and animal processing facilities is essential for preventing disease outbreaks and ensuring food safety.
Lonzabac 12.30 is used in disinfecting animal housing, milking equipment, and feed storage containers, reducing the risk of bacterial infections in dairy cows, poultry, and swine.
Lonzabac 12.30 is also incorporated into animal footbaths and veterinary disinfectants, helping to control the spread of zoonotic diseases that can transfer between animals and humans.
Lonzabac 12.30 is used in crop protection formulations to prevent fungal and bacterial contamination of agricultural produce, ensuring that harvested crops remain fresh and free from spoilage microorganisms.
Lonzabac 12.30 is widely used across multiple industries due to its broad-spectrum antimicrobial activity, high stability in organic-rich environments, and compatibility with various cleaning and disinfection formulations.
Its effectiveness against bacteria, fungi, and enveloped viruses makes it a key ingredient in industrial and institutional hygiene products, ensuring surfaces, equipment, and water systems remain free from harmful microbial contamination.
Lonzabac 12.30 plays a crucial role in hospital-grade disinfectants, surface sanitizers, and medical equipment cleaners, helping to maintain strict hygiene standards in healthcare settings.
It is frequently incorporated into disinfectant formulations used for cleaning high-touch surfaces such as hospital beds, operating tables, door handles, and medical instruments, where microbial contamination poses a high risk of infections.
Additionally, due to its biocidal action against drug-resistant pathogens like Methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile, it is used in terminal cleaning procedures in hospitals to ensure complete disinfection of patient rooms, ICUs, and surgical theaters.
Lonzabac 12.30 is also found in antimicrobial hand sanitizers and skin antiseptic formulations, providing healthcare professionals with an effective means of hand hygiene to prevent the spread of infectious diseases within medical facilities.
In food processing plants, commercial kitchens, and beverage manufacturing facilities, maintaining a hygienic environment is essential to prevent foodborne illnesses caused by bacterial and fungal contamination.
Lonzabac 12.30 is widely used in sanitizing food-contact surfaces, including cutting boards, conveyor belts, food processing machinery, and storage containers, ensuring that no harmful pathogens remain on equipment after cleaning procedures.
It is particularly useful in meat and poultry processing plants, where organic residues like blood and fats can compromise the effectiveness of traditional disinfectants, but Lonzabac 12.30 remains active even in heavily soiled conditions.
Lonzabac 12.30 is used in dairy production facilities, breweries, and beverage bottling plants, where it helps to eliminate bacterial biofilms that can form inside pipelines, fermenters, and bottling equipment, ensuring that products remain safe for consumption and free from spoilage microorganisms.
Microbial contamination in water systems, cooling towers, and wastewater treatment plants can lead to the proliferation of harmful bacteria such as Legionella pneumophila, which is responsible for Legionnaires’ disease.
Lonzabac 12.30 is widely used in industrial water treatment formulations to inhibit bacterial growth, prevent biofilm formation, and maintain water purity in closed-loop systems, cooling towers, and industrial boilers.
Its stability in various pH conditions and high resistance to organic interference makes it ideal for maintaining microbiological control in large-scale water circulation systems.
Additionally, Lonzabac 12.30 is used in wastewater treatment plants to prevent the growth of odor-causing bacteria and fungi, improving overall sanitation and ensuring that treated water meets regulatory standards.
Lonzabac 12.30 is a versatile antimicrobial agent with widespread applications in healthcare, food processing, industrial cleaning, water treatment, paint preservation, textiles, agriculture, and personal care products.
Its broad-spectrum efficacy, stability in organic-rich environments, and compatibility with various formulations make it an essential ingredient in disinfection and hygiene solutions across multiple industries.
Safety Profile Of Lonzabac 12.30:
Lonzabac 12.30, despite its effectiveness as a broad-spectrum antimicrobial agent, presents several potential hazards that require careful handling and appropriate safety measures.
While it is considered low in toxicity when used at recommended concentrations, exposure to highly concentrated forms of the chemical can pose health risks to humans, animals, and the environment.
Below are the key hazards associated with Lonzabac 12.30, explained in longer and more detailed sentences.
Lonzabac 12.30, when handled in its undiluted or highly concentrated form, can cause moderate to severe skin irritation upon direct contact.
This occurs because it disrupts cell membranes, a mechanism that makes it highly effective against bacteria but also potentially damaging to human skin cells.
If the solution comes into contact with the skin, redness, dryness, burning sensations, and even chemical burns may develop, particularly if exposure is prolonged or repeated over time.
Individuals with pre-existing skin conditions, such as eczema or dermatitis, may experience exacerbation of symptoms, leading to increased skin sensitivity, peeling, or inflammation.
To prevent these effects, it is recommended that individuals handling Lonzabac 12.30 wear protective gloves, long-sleeved clothing, and other appropriate personal protective equipment (PPE) to minimize skin exposure.
One of the most significant hazards of Lonzabac 12.30 is its potential to cause severe eye irritation or even permanent eye damage if it comes into direct contact with the eyes.
Because it functions as a biocidal surfactant, it can break down the protective lipid layers of the eye’s surface, leading to intense irritation, redness, tearing, swelling, and blurred vision.
In severe cases, chemical burns to the cornea may occur, potentially resulting in long-term vision impairment.
If exposure occurs, the affected individual should immediately flush their eyes with clean water for at least 15 minutes and seek medical attention to prevent further damage.
Safety goggles or full-face shields should always be worn when handling concentrated solutions of Lonzabac 12.30 to prevent accidental eye exposure.
Although Lonzabac 12.30 is typically formulated as a liquid solution, it may produce aerosols or vapors when sprayed, misted, or used in industrial-scale applications.
Inhalation of these vapors or fine droplets can cause irritation of the respiratory tract, leading to coughing, shortness of breath, throat discomfort, and nasal congestion.
Individuals with pre-existing respiratory conditions, such as asthma or chronic bronchitis, may be more susceptible to worsening symptoms, including wheezing, chest tightness, and difficulty breathing.
Prolonged exposure in poorly ventilated areas may lead to headaches, dizziness, or nausea due to the chemical’s mild neurotoxic effects.
To minimize inhalation risks, Lonzabac 12.30 should always be used in well-ventilated areas, and respiratory protection (such as an N95 or chemical-resistant mask) should be worn when working with high concentrations in aerosolized form.
