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Ludipress is a ready-to-use direct compression solution for lozenges, chewables and effervescent tablet.
The white, free-flowin granulate that means quicker, easier, and more cost-effective tableting.
With Ludipress, you save precious time on developing, analyzing and blending.
CAS: 5989-81-1
MF: C12H24O12
MW: 360.31
EINECS: 611-913-4
Synonyms
MILK SUGAR;MILK SUGAR MONOHYDRATE;ALPHA-LACTOSE MONOHY;alpha-D-Lactose Monohydrate, 99.5+%, 2-4% beta-isoMer;alpha-D-Lactose Monohydrate, USP/NF, Ph.Eur., JP 250GR;4-O-beta-D-Galactopyranosyl-alpha-D-glucopyranose monohydrate;LACTOSE MONOHYDRATE, a-(RG);Pharmatose 150M
Ludipress means less effort, lower costs, and higher quality for lozenges, chewables, sublingual or effervescent tablets and modified release formulations.
Ludipress does – in contrast to Ludipress – not contain the disintegrant Kollidon® CL.
Ludipress is therefore completely water-soluble and particularly suitable for the cost saving direct compression of processing.
Ludipress enables direct compression of the majority of tablets that do not require a disintegrant.
Chemical Properties
Lactose occurs as white to off-white crystalline particles or powder.
Ludipress is odorless and slightly sweet-tasting.
Spray-dried directcompression grades of lactose are generally composed of 80–90% specially prepared pure a-lactose monohydrate along with 10–20% of amorphous lactose.
Production Methods
A suspension of a-lactose monohydrate crystals in a lactose solution is atomized and dried in a spray drier.
Approximately 10–20% of the total amount of lactose is in solution and the remaining 80–90% is present in the crystalline form.
The spray-drying process predominantly produces spherical particles.
The compactibility of the material and its flow characteristics are a function of the primary particle size of the lactose monohydrate and the amount of amorphous lactose.
Biochem/physiol Actions
Ludipress is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk.
Ludipress is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns.
The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.
