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Mackamine LA acts as a performance stabilizer and foam controller under extreme chemical conditions.
In personal care, Mackamine LA functions as a mildness enhancer, foam quality improver, and sensory modifier, contributing to user comfort and product aesthetics rather than chemical resistance.
CAS Number: 1643-20-5 (typical for lauryldimethylamine oxide)
EC/EINECS Number: 216-700-6 (for lauryldimethylamine oxide)
Chemical Name: Lauramine Oxide (general commercial trade name)
Chemical Formula (example lauryldimethylamine oxide): C14H31NO
Molecular Weight (approx.): ~229.4 g/mol
SYNONYMS:
Lauramine oxide, Dodecyldimethylamine oxide, Dimethyldodecylamine N-oxide, N-dodecyl-N,N-dimethylamine oxide, Laurylamine oxide, Lauryldimethylamine N-oxide, DDAO, Ammonyx LO
Mackamine LA is a vegetable-derived grade of lauramine oxide that offers excellent foam boosting and foam stability.
Mackamine LA is compatible with most surfactants and, due to the absence of amide or ester groups, will not hydrolyze in acidic systems.
Mackamine LA is also stable in highly alkaline products and in the presence of hypochlorite bleach.
Mackamine LA is a commercial vegetable-derived grade of lauramine oxide, a type of amphoteric surfactant widely used in cleaning and personal care formulations.
Mackamine LA is valued for its excellent foam boosting, foam stability, and conditioning properties, and is compatible with many other surfactants.
Mackamine LA does not contain amide or ester groups and is stable in both acidic and alkaline systems.
Mackamine LA is a pure, vegetable-derived foaming agent.
Mackamine LA acts as a secondary surfactant and conditioning agent.
Mackamine LA is compatible with most surfactants and does not hydrolyze in acid systems.
Mackamine LA is a salt and preservative-free grade.
Mackamine LA is also stable in highly alkaline products.
Mackamine LA is suitable for shampoos, bubble bath, hand soaps, face and body cleansers.
Mackamine LA is a vegetable derived grade of lauramine oxide that provides excellent foam boosting and foam stability.
Mackamine LA is compatible with most surfactants, contains no amide or ester groups and will not hydrolyze in acid systems.
Mackamine LA is also stable in highly alkaline products.
USES and APPLICATIONS of MACKAMINE LA:
Viscosity control is another area where performance diverges.
In industrial products, viscosity is usually kept low for pumping, spraying, or automated dosing, and Mackamine LA’s role is mainly to maintain clarity and stability rather than build thickness.
In personal care products, however, Mackamine LA actively contributes to viscosity enhancement when combined with anionic surfactants and electrolytes, enabling the creation of thick, aesthetically pleasing gels without excessive salt addition.
From a formulation safety perspective, industrial products prioritize chemical resistance and storage stability, while personal care products prioritize dermatological compatibility.
In industrial cleaners, Mackamine LA may be used at relatively higher active levels because end-user skin contact is limited or controlled.
In personal care products, usage levels of Mackamine LA are carefully optimized to balance performance with long-term skin and eye tolerance.
In summary, Mackamine LA plays two very different roles depending on the application.
In industrial cleaning, Mackamine LA acts as a performance stabilizer and foam controller under extreme chemical conditions.
In personal care, Mackamine LA functions as a mildness enhancer, foam quality improver, and sensory modifier, contributing to user comfort and product aesthetics rather than chemical resistance.
The same molecule delivers value in both sectors, but for fundamentally different reasons rooted in formulation goals and end-use expectations.
Mackamine LA is broadly used as a surfactant and foam boosting agent.
Personal Care & Cosmetics use of Mackamine LA: Shampoos and conditioners, Body washes and skin cleansers, Liquid hand soaps, and Bubble baths.
Mackamine LA can act as a secondary surfactant, enhancing foam volume, stability, and mild conditioning feel.
Home & Industrial Cleaning uses of Mackamine LA: Liquid dishwashing products, Bleach and alkaline cleaners, Hard-surface cleaners, Laundry and institutional cleaning formulations.
Mackamine LA is especially useful where stable foam and emulsification is required even in complex formulations.
In industrial cleaning and personal care, Mackamine LA functions as a secondary surfactant and conditioning/foam-enhancing agent in products ranging from shampoos to alkaline cleaners.
Mackamine LA provides excellent foam boosting and stability.
Mackamine LA exhibits good viscosity and low level of residual amine.
From an environmental and regulatory perspective, Mackamine LA is typically regarded as readily biodegradable when used in formulations and does not bioaccumulate significantly.
Mackamine LA aligns well with modern formulation trends aimed at improving environmental profiles while maintaining performance.
Vegetable-derived feedstocks used in many commercial grades further support sustainability claims, although exact sourcing depends on the manufacturer.
Finally, in practical use, Mackamine LA is rarely used as the sole surfactant.
Mackamine LA's real strength lies in synergistic blending, where small additions (often 2–6% active matter in finished products) dramatically improve foam quality, stability, mildness, and formulation robustness.
This makes Mackamine LA a highly cost-effective functional ingredient rather than just a primary cleaning agent.
In industrial and institutional cleaning, Mackamine LA is primarily valued for its robustness and chemical tolerance.
Industrial formulations of Mackamine LA often operate under extreme conditions such as high alkalinity, strong oxidizers (e.g. bleach), elevated electrolyte levels, and hard water.
Under these conditions, many surfactants lose effectiveness or destabilize, but Mackamine LA maintains its surfactant activity and structural integrity.
Its amine oxide chemistry allows Mackamine LA to remain stable and functional even when exposed to sodium hydroxide, sodium hypochlorite, or high salt concentrations, which is why it is frequently used in heavy-duty cleaners, degreasers, and disinfectants.
In industrial systems, foam is not always desired for aesthetic reasons, but controlled and persistent foam can be functionally important.
Mackamine LA creates foam that is mechanically stable rather than airy, meaning it resists collapse under shear and rinsing.
This is beneficial in applications such as spray-on cleaners, CIP (clean-in-place) systems, and vertical surface cleaners, where foam helps extend contact time and improve soil removal.
In these applications, Mackamine LA is used mainly for foam control, emulsification of oily soils, and formulation stability, rather than skin compatibility.
By contrast, in personal care formulations, Mackamine LA is selected primarily for its sensory and mildness benefits rather than chemical toughness.
Shampoos, body washes, and hand soaps operate at much lower alkalinity and are designed for frequent human contact.
In these systems, Mackamine LA functions as a secondary surfactant that softens the cleansing action of stronger anionic surfactants such as SLES or ALS.
Mackamine LA modifies micelle structures, reducing the tendency of surfactants to strip skin lipids or denature proteins, which results in a noticeably gentler feel on skin and hair.
Foam performance in personal care is also fundamentally different from industrial use.
Here, the goal is not durability under harsh conditions but foam quality and sensory perception.
Mackamine LA produces a creamy, dense, and uniform foam that feels rich and luxurious, even when total surfactant levels are reduced.
This allows formulators to improve consumer perception while maintaining mildness and lowering irritation potential.
The foam collapses smoothly during rinsing, leaving less residue compared to harsher foaming agents.
BENEFITS & FUNCTIONAL CHARACTERISTICS of MACKAMINE LA:
Excellent Foam Boosting and Foam Stability — Mackamine LA increases lather quality and persistence.
Compatibility with Many Surfactants — Mackamine LA can be used with anionic, non-ionic, cationic, and amphoteric systems.
Vegetable-Derived Grade — many commercial variants use coconut or palm oil feedstocks.
Stable Across pH Ranges — effective in both acidic and alkaline environments.
Conditioning Effect — mild on skin and hair compared to some anionic surfactants.
FUNCTIONS of MACKAMINE LA:
Anti-Static Agent, Detergent, Emulsifier, Foam Booster, Foam Stabilizer, Foaming Agent, Surfactant, Surfactant (Amphoteric), Thickener, Wetting Agent
LABELING CLAIMS of MACKAMINE LA:
Amide-free, Animal Products-free, Biodegradable, Cold Processable, Diethanolamide-free, Diethanolamine-free, Diethanolamine-free (DEA)-free, Formaldehyde-free, Glycerin-free, Monoethanolamine (MEA)-free, Naturally Derived, Plant-Based, Preservative-free, Salt-free
PHYSICAL and CHEMICAL PROPERTIES of MACKAMINE LA:
Chemical Name: Lauramine Oxide (general commercial trade name)
Underlying Chemical Family: Amine Oxides
Common Structure: alkyl dimethylamine N-oxide with a long alkyl chain (typically C12 derived from lauric sources)
CAS Number: 1643-20-5 (typical for lauryldimethylamine oxide)
EC/EINECS Number: 216-700-6 (for lauryldimethylamine oxide)
Chemical Formula (example lauryldimethylamine oxide): C14H31NO
Molecular Weight (approx.): ~229.4 g/mol
Physical Form: Clear liquid at room temperature (Mackamine LA specification).
Appearance: Clear to pale liquid; low color – Gardner ≤1.0.
pH (10% aqueous): ~7.0–9.0 (neutral to mildly alkaline).
Density: ~0.97 g/cm³ at 25 °C.
Amine Oxide Content: ~29–31 % (typical commercial specification).
Free Amine Content: <1 % (low residual amine).
Hydrogen Peroxide Content (impurity): <0.2 %.
Stability: stable in both highly acidic and alkaline products;
does not hydrolyze easily due to absence of ester/amide groups.
Chemical behavior: As an amine oxide surfactant,
it has both hydrophobic (alkyl chain) and hydrophilic (amine oxide) segments,
giving it strong amphiphilic character for detergency and foam stabilization.
Physical state: Liquid
Appearance: Clear to slightly hazy liquid
Color: Colorless to pale yellow
Odor: Mild, characteristic
Active matter (amine oxide): ~29–31 %
Water content: Balance to 100 %
Density (25 °C): ~0.96–0.99 g/cm³
pH (10% aqueous solution): ~7.0–9.0
Viscosity (25 °C): Low to medium (typically 50–300 mPa·s, grade dependent)
Solubility in water: Completely soluble
Solubility in organic solvents: Limited; soluble in polar solvents
Cloud point: Not sharply defined (surfactant solution)
Free amine content: < 1 %
Hydrogen peroxide content: < 0.2 %
Pour point: Typically above 0 °C (varies with formulation)
Foaming tendency: High (foam-boosting surfactant)
Chemical type: Amine oxide surfactant
Surfactant class: Amphoteric / zwitterionic
Ionic character:
• Cationic-like under acidic conditions
• Non-ionic-like under neutral to alkaline conditions
Chemical stability: Stable under normal storage and use conditions
pH stability range: Broad (effective in acidic, neutral, and alkaline systems)
Hydrolytic stability: High (contains no ester or amide groups)
Oxidative stability: Good; compatible with bleach and oxidizing systems
Electrolyte tolerance: High (stable in presence of salts and hard water ions)
Compatibility: Compatible with anionic, nonionic, cationic, and amphoteric surfactants
Reactivity: Low; does not readily react with common formulation ingredients
Biodegradability: Readily biodegradable (typical for amine oxide surfactants)
Bioaccumulation potential: Low
Surface activity: High; reduces surface tension effectively
Foam behavior: Produces dense, stable, creamy foam
Emulsification ability: Good for oils and greasy soils
Hydrophobic group: C12 alkyl chain (lauryl-based, vegetable derived)
Hydrophilic group: Dimethylamine oxide
Amphiphilic nature: Strong (excellent detergency and foam synergy)
Micelle formation: Efficient; improves micelle packing in mixed systems
FIRST AID MEASURES of MACKAMINE LA:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of MACKAMINE LA:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of MACKAMINE LA:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of MACKAMINE LA:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of MACKAMINE LA:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of MACKAMINE LA:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
