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Magnesium octadecanoate finds widespread use in pharmaceuticals and cosmetics industries as a release agent and lubricant, leveraging its softness, insolubility, and low toxicity to enhance production processes.
With versatile applications spanning sectors such as cosmetics, food, polymer, rubber, and paint, magnesium octadecanoate serves as a gelling agent, stabilizer, antiadhesive, and plasticizer, offering tailored manufacturing options in terms of size and density.
As a vital additive in pharmaceuticals, magnesium octadecanoate serves as a flow agent in capsules and tablets, ensuring consistency and quality control, while also finding utility in the food industry for its emulsifying, binding, thickening, and anticaking properties.
CAS Number: 557-04-0
EC Number: 209-150-3
Molecular Formula: C36H70MgO4
Molecular Weight (g/mol): 591.257
Synonyms: 209-150-3 [EINECS], 3919702 [Beilstein], 557-04-0 [RN], 70097M6I30, Dibasic magnesium stearate, Dioctadécanoate de magnésium [French] [ACD/IUPAC Name], Magnesium dioctadecanoate [ACD/IUPAC Name], MAGNESIUM OCTADECANOATE, Magnesium stearate [JAN] [JP15] [NF] [USP], Magnesiumdioctadecanoat [German] [ACD/IUPAC Name], MFCD00036391 [MDL number], OCTADECANOIC ACID MAGNESIUM SALT, Octadecanoic acid, magnesium salt, Octadecanoic acid, magnesium salt (2:1) [ACD/Index Name], stearic acid magnesium salt, Stearic acid, magnesium salt, synpro 90, Synpro Magnesium Stearate 90, WI4390000, (OCTADECANOYLOXY)MAGNESIO OCTADECANOATE, [557-04-0] [RN], 212132-26-8 [RN], EINECS 209-150-3, Magnesium [ACD/Index Name] [ACD/IUPAC Name], magnesium distearate, Magnesium stearate (contain palmitic acid), Magnesium stearate (JP17/NF), Magnesium Stearate NF, Magnesium Stearate NF EP FCC Kosher, MAGNESIUM(2+) DIOCTADECANOATE, MAGNESIUM(2+) ION BIS(N-OCTADECANOATE), magnesium(2+) ion bis(octadecanoate), Magnesium(II) Stearate, magnesiumstearate, octadecanoate, PARTECK LUB MST, Petrac MG 20NF, SM-P, UNII:70097M6I30, UNII-70097M6I30, 硬脂酸镁 [Chinese], MAGNESIUM STEARATE, 557-04-0, Magnesium octadecanoate, Magnesium distearate, Dibasic magnesium stearate, Octadecanoic acid, magnesium salt, magnesium(ii) stearate, Synpro 90, Petrac MG 20NF, Stearic acid, magnesium salt, NS-M (salt), SM-P, Magnesium stearate g, Synpro Magnesium Stearate 90, HSDB 713, Magnesii stearas, Magnesium distearate, pure, EINECS 209-150-3, NP 1500, SM 1000, CHEBI:9254, AI3-01638, magnesium dioctadecanoate, UNII-70097M6I30, Octadecanoic acid, magnesium salt (2:1), 70097M6I30, DTXSID2027208, MAGNESIUM STEARATE (II), MAGNESIUM STEARATE [II], Magnesium stearate [JAN], C36H70MgO4, Magnesium stearate [JAN:NF], DAYCLING, Magnesium stearate, tech, SCHEMBL935, DTXCID307208, Magnesium stearate (JP17/NF), MAGNESIUM STEARATE [MI], CHEMBL2106633, MAGNESIUM STEARATE [HSDB], MAGNESIUM STEARATE [INCI], Stearic Acid Magnesium(II) Salt, MAGNESIUM STEARATE [VANDF], HY-Y1054, MAGNESIUM STEARATE [WHO-DD], AKOS015915201, DB14077, MAGNESII STEARAS [WHO-IP LATIN], CS-0016049, NS00080495, S0238, D02189, A830764, Q416713
Magnesium octadecanoate is the chemical compound with the formula Mg(C18H35O2)2.
Magnesium octadecanoate is a soap, consisting of salt containing two equivalents of stearate (the anion of stearic acid) and one magnesium cation (Mg2+).
Magnesium octadecanoate is a white, water-insoluble powder.
Magnesium octadecanoate's applications exploit its softness, insolubility in many solvents, and low toxicity.
Magnesium octadecanoate is used as a release agent and as a component or lubricant in the production of pharmaceuticals and cosmetics.
Magnesium octadecanoate is the magnesium salt of stearic acid.
Magnesium octadecanoates anhydrate, dihydrate and trihydrate forms have been prepared.
The tabletting of the blends of Magnesium octadecanoate and lactose granules has been described.
The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined.
Magnesium octadecanoate is widely used lubricant in pharmaceutical industry.
Magnesium octadecanoate also plays a role in delaying the process of dissolution.
Magnesium octadecanoates detection in tablets by laser-induced breakdown spectroscopy has been proposed.
Magnesium octadecanoate, the salt of stearic acid, is widely employed as an inactive component in making pharmaceutical tablets.
Magnesium octadecanoate is towards plastic applications.
Magnesium octadecanoate is used as gelling agent, stabilizer, antiadhesive and plasticizer as a lot of different functions in primary sectors ;cosmetics, pharmacy, food, polymer, rubber and paint.
Magnesium octadecanoate can be manufactured with demanded particular size and density, according to production process and industry.
Magnesium octadecanoate is involved in the production of medical tablets, capsules, powders and polymer formulation.
Magnesium octadecanoate is also used as a lubricant for tablets, anti-adherent, in dry coating and as a binding agent.
Magnesium octadecanoate is an important ingredient in baby formulas.
Further, Magnesium octadecanoate is used in the hydrogenation process.
In addition to this, Magnesium octadecanoate is used to bind the sugar in hard candies like mints.
Magnesium octadecanoate is a white, water-insoluble fine powder.
Magnesium octadecanoate is a simple salt made up of two substances, a saturated fat called stearic acid and the mineral magnesium.
Magnesium octadecanoate is the most common additive that is primarily used in capsules and tablets as it is considered a ‘flow agent’ so Magnesium octadecanoate prevents the individual ingredients in a capsule from sticking together.
Magnesium octadecanoate helps improves the consistency and quality control of capsules.
Magnesium octadecanoate is used in the food industry as an emulsifier, binder and thickener, as well as an anticaking, lubricant, and antifoaming agent.
Magnesium octadecanoate is the magnesium salt of stearic acid.
Magnesium octadecanoates anhydrate, dihydrate and trihydrate forms have been prepared.
The tabletting of the blends of Magnesium octadecanoate and lactose granules has been described.
The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined.
Magnesium octadecanoate is widely used lubricant in pharmaceutical industry.
Magnesium octadecanoate also plays a role in delaying the process of dissolution.
Magnesium octadecanoates detection in tablets by laser-induced breakdown spectroscopy has been proposed.
Magnesium octadecanoate is a fine white powder that adds bulk to cosmetic and personal care products, while also providing them with a rich slippery feeling and adhesion.
Magnesium octadecanoate makes products feel good to the touch and enhances the spreadability.
Magnesium octadecanoate can also act as a lubricant and an anti-caking agent.
Magnesium octadecanoate is generally found in products like creams, lotions, and powders where Magnesium octadecanoate improves the overall performance and shelf life of the formulation.
Magnesium octadecanoate is soluble in hot water and has the formula Mg(C18H35O2)2.
Magnesium octadecanoate, a synthetic soap that consists of a mixture of magnesium salts of fatty acids, principally palmitic and stearic acid.
Magnesium octadecanoate is one of the most commonly used excipients and corresponds to the chemical formula, C36H70MgO4.
Magnesium octadecanoate is described in pharmacopoeia as a mixture of organic acids, chiefly Magnesium octadecanoate, and magnesium palmitate.
Magnesium octadecanoate is supplied as a very fine, light, white impalpable powder.
When touched, Magnesium octadecanoate feels greasy and readily adheres to the skin.
Magnesium octadecanoate is a solid, white powder at room temperature.
Magnesium octadecanoate is a FDA-approved inactive ingredient commonly used in the pharmaceutical industry as a lubricant and release agent in the manufacture of tablet, capsule, and powder dosage forms.
Magnesium octadecanoate is generally recognized as safe by the FDA.
Magnesium octadecanoate exists as a salt form and is useful for it's lubricating properties for capsules and tablets in industry.
Magnesium octadecanoate is used to help prevent pharmaceutical ingredients from adhering to industry equipment.
Magnesium octadecanoate may be derived from both plant and animal sources.
Magnesium octadecanoate is a common additive used in the pharmaceutical industry.
Magnesium octadecanoate is a white, odorless, and tasteless powder that is highly insoluble in water, but soluble in organic solvents.
The chemical formula for Magnesium octadecanoate is Mg(C18H35O2)2.
Have you ever wondered what that coating on your medications and vitamins is? It’s an additive made from Magnesium octadecanoate.
Magnesium octadecanoate is a fine white powder that sticks to your skin and is greasy to the touch.
Magnesium octadecanoate’s a simple salt made up of two substances, a saturated fat called stearic acid and the mineral magnesium.
Stearic acid can also be found in many foods, such as:
chicken
eggs
cheese
chocolate
walnuts
salmon
cotton seed oil
palm oil
coconut oil
Magnesium octadecanoate is commonly added to many foods, pharmaceuticals, and cosmetics.
In medications and vitamins, Magnesium octadecanoate's primary purpose is to act as a lubricant.
Uses of Magnesium octadecanoate:
Magnesium octadecanoate is often used as an anti-adherent in the manufacture of medical tablets, capsules and powders.
In this regard, the substance is also useful because Magnesium octadecanoate has lubricating properties, preventing ingredients from sticking to manufacturing equipment during the compression of chemical powders into solid tablets; Magnesium octadecanoate is the most commonly used lubricant for tablets.
However, Magnesium octadecanoate might cause lower wettability and slower disintegration of the tablets and slower and even lower dissolution of the drug.
Magnesium octadecanoate can also be used efficiently in dry coating processes.
In the production of pressed candies, Magnesium octadecanoate serves as a release agent.
Magnesium octadecanoate is also used to bind sugar in hard candies such as mints.
Magnesium octadecanoate is a common ingredient in baby formulas.
In the EU and EFTA Magnesium octadecanoate is listed as food additive E470b.
Uses of Magnesium octadecanoate as excipient in pharmaceuticals:
Magnesium octadecanoate is a widely used excipient in the pharmaceutical industry, serving a variety of purposes in drug formulation and manufacturing.
Here are some of the major uses of Magnesium octadecanoate in pharmaceutical products:
Lubricant:
One of the most common uses of Magnesium octadecanoate in pharmaceutical products is as a lubricant.
Magnesium octadecanoate is added to drug formulations to reduce friction between particles and facilitate their movement through manufacturing equipment, such as tablet presses and capsule filling machines.
This helps to ensure consistent and efficient production of drug products.
Magnesium octadecanoate is used as a lubricant for tablets and capsules in a range of 0.2 to 5%.
Anti-adherent:
Magnesium octadecanoate can also serve as an anti-adherent in pharmaceutical products.
Magnesium octadecanoate is added to prevent drug particles from sticking to the surfaces of manufacturing equipment, which can cause blockages or uneven dosing.
Flow agent:
In addition to lubrication, Magnesium octadecanoate can also improve the flow properties of drug powders.
Magnesium octadecanoate is added to reduce the cohesive forces between particles and improve their flowability, making Magnesium octadecanoate easier to handle and process them during manufacturing.
Magnesium octadecanoate has various uses in both cosmetics and skincare products.
Primarily, Magnesium octadecanoate enhances the texture and performance of formulations within the cosmetic industry.
Cosmetic products:
Magnesium octadecanoate is a good anti-caking agent that works wonders with cosmetic products.
Magnesium octadecanoate promotes a slippery texture that enhances the blend and spreadability of products like blushes, eyeshadows, and foundations.
Magnesium octadecanoate also aids with adherence to allow for long-lasting wear.
Skin care:
Magnesium octadecanoate is often utilized as a thickening agent and emulsifier.
Magnesium octadecanoate helps to stabilize and bind the ingredients in creams, lotions, and moisturizers, ensuring a consistent and smooth texture.
Magnesium octadecanoate also aids in the absorption of oils and active ingredients, facilitating their delivery into the skin for improved efficacy.
Applications of Magnesium octadecanoate:
Magnesium octadecanoate may be used as excipient in the formulations of diclofenac sodium tablets.
Magnesium octadecanoate may be used for the preparation of tramadol HCl matrix tablets.
Manufacturing of Magnesium octadecanoate:
Magnesium octadecanoate can be derived from various sources such as animal, vegetable, and synthetic materials.
Animal-derived Magnesium octadecanoate is usually sourced from beef or pork tallow, while vegetable-derived Magnesium octadecanoate is obtained from hydrogenated cottonseed or palm oil.
Synthetic Magnesium octadecanoate is produced by combining magnesium oxide or magnesium hydroxide with stearic acid.
Magnesium octadecanoate is produced by the reaction of sodium stearate with magnesium salts or by treating magnesium oxide with stearic acid.
Occurrence of Magnesium octadecanoate:
Magnesium octadecanoate is a major component of bathtub rings.
When produced by soap and hard water, Magnesium octadecanoate and calcium stearate both form a white solid insoluble in water, and are collectively known as soap scum.
Origin of Magnesium octadecanoate:
Magnesium octadecanoate is generally produced by the reaction between magnesium salts and stearic acid.
Stearic acid is neutralized with magnesium hydroxide or magnesium carbonate, resulting in the formation of Magnesium octadecanoate.
Magnesium octadecanoate is then purified, dried, and milled into a fine powder for use in cosmetics and other applications.
Handling and storage of Magnesium octadecanoate:
Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.
Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids
Stability and reactivity of Magnesium octadecanoate:
Reactivity:
No data available
Chemical stability:
Magnesium octadecanoate is chemically stable under standard ambient conditions (room temperature).
Possibility of hazardous reactions:
No data available
Conditions to avoid:
no information available
Incompatible materials:
Strong oxidizing agents
Safety of Magnesium octadecanoate:
Magnesium octadecanoate is generally considered safe for human consumption at levels below 2500 mg per kg of body weight per day and is classified in the United States as generally recognized as safe (GRAS).
In 1979, the FDA's Subcommittee on GRAS Substances (SCOGS) reported, "There is no evidence in the available information on Magnesium octadecanoate that demonstrates, or suggests reasonable grounds to suspect, a hazard to the public when they are used at levels that are now current and in the manner now practiced, or which might reasonably be expected in the future."
Magnesium octadecanoate is generally safe for use and has no reported side effects.
Magnesium octadecanoate also does not clog pores or cause breakouts.
Patch testing of Magnesium octadecanoate with Magnesium octadecanoate can be done for sensitive skin, but is not typically required.
Depending on the source and manufacturing of this compound, Magnesium octadecanoate can be vegan and halal.
First aid measures of Magnesium octadecanoate:
If inhaled:
After inhalation:
Fresh air.
In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
Indication of any immediate medical attention and special treatment needed:
No data available
Firefighting measures of Magnesium octadecanoate:
Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
Special hazards arising from the substance or mixture:
Carbon oxides
Magnesium oxide
Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus.
Further information:
none
Accidental release measures of Magnesium octadecanoate:
Personal precautions, protective equipment and emergency procedures:
Advice for non-emergency personnel:
Avoid inhalation of dusts.
Evacuate the danger area, observe emergency procedures, consult an expert.
Environmental precautions:
No special precautionary measures necessary.
Methods and materials for containment and cleaning up:
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
Avoid generation of dusts.
Identifiers of Magnesium octadecanoate:
CAS Number: 557-04-0
ChEBI: CHEBI:9254
ChemSpider: 10704
ECHA InfoCard: 100.008.320
E number: E572 (acidity regulators, ...)
PubChem CID: 11177
UNII: 70097M6I30
CompTox Dashboard (EPA): DTXSID2027208
InChI: InChI=1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
Key: HQKMJHAJHXVSDF-UHFFFAOYSA-L
InChI=1/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
Key: HQKMJHAJHXVSDF-NUQVWONBAM
SMILES: [Mg+2].[O-]C(=O)CCCCCCCCCCCCCCCCC.[O-]C(=O)CCCCCCCCCCCCCCCCC
CAS: 557-04-0
Molecular Formula: C36H70MgO4
Molecular Weight (g/mol): 591.257
MDL Number: MFCD00036391
InChI Key: HQKMJHAJHXVSDF-UHFFFAOYSA-L
PubChem CID: 11177
ChEBI: CHEBI:9254
IUPAC Name: magnesium;octadecanoate
SMILES: CCCCCCCCCCCCCCCCCC(=O)[O-].CCCCCCCCCCCCCCCCCC(=O)[O-].[Mg+2]
Synonym(s): Stearic acid magnesium salt
Linear Formula: [CH3(CH2)16CO2]2Mg
CAS Number: 557-04-0
Molecular Weight: 591.24
Beilstein: 3919702
EC Number: 209-150-3
MDL number: MFCD00036391
PubChem Substance ID: 24865972
NACRES: NA.22
Compound Formula: [CH3(CH2)16CO2]2Mg
Molecular Weight: 591.24
Appearance: White Powder
Melting Point: 200°C
Boiling Point: N/A
Density: N/A
Solubility in H2O: N/A
Exact Mass: 590.512452 g/mol
Monoisotopic Mass: 590.512452 g/mol
Linear Formula: [CH3(CH2)16CO2]2Mg
MDL Number: MFCD00036391
EC No.: 209-150-3
Beilstein/Reaxys No.: 3919702
Pubchem CID: 11177
IUPAC Name: magnesium; octadecanoate
SMILES: CCCCCCCCCCCCCCCCCCC(=O)[O-].CCCCCCCCCCCCCCCCC(=O)[O-].[Mg+2]
InchI Identifier: InChI=1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
InchI Key: HQKMJHAJHXVSDF-UHFFFAOYSA-L
Properties of Magnesium octadecanoate:
Chemical formula: Mg(C18H35O2)2
Molar mass: 591.27 g/mol
Appearance: light white powder
Odor: slight
Density: 1.026 g/cm3
Melting point: 88.5 °C (191.3 °F; 361.6 K)
Solubility in water: 0.003 g/100 mL (15 °C)
0.004 g/100 mL (25 °C)
0.008 g/100 mL (50 °C)
Solubility: negligible in ether and alcohol slightly soluble in benzene
grade: technical grade
Quality Level: 100
form: powder
composition:
palmitate salt, 25%
stearate salt, 65%
mp: 200 °C (lit.)
SMILES string: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
InChI key: HQKMJHAJHXVSDF-UHFFFAOYSA-L
Specifications of Magnesium octadecanoate:
Melting Point: 148°C to 152°C
Quantity: 250 g
Solubility Information: Slightly soluble in benzene. Insoluble in water,alcohol and ether.
Formula Weight: 591.27
Chemical Name or Material: Magnesium octadecanoate
Names of Magnesium octadecanoate:
IUPAC name:
Magnesium octadecanoate
