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MAGNESIUM CITRATE

CAS NUMBER: 3344-18-1

EC NUMBER: 222-093-9

MOLECULAR FORMULA: C12H10Mg3O14

MOLECULR WEIGHT: 451.12

IUPAC NAME: trimagnesium;2-hydroxypropane-1,2,3-tricarboxylate


Magnesium is a naturally occurring mineral that is important for many systems in the body, especially the muscles and nerves. 
Magnesium Citrate also increases water in the intestines.

Magnesium Citrate is used as a laxative to treat occasional constipation.
Magnesium Citrate is also used to empty the colon (large intestine, bowel) before a colonoscopy (examination of the inside of the colon to check for colon cancer and other abnormalities) or certain medical procedures.

Why is Magnesium Citrate medication prescribed?
Magnesium Citrate is used to treat occasional constipation on a short-term basis. 
Magnesium Citrate is in a class of medications called saline laxatives. 
Magnesium Citrate works by causing water to be retained with the stool. 
This increases the number of bowel movements and softens the stool so it is easier to pass.

Magnesium Citrate can be used to help clean out your intestines before a colonoscopy
Magnesium Citrate is an osmotic laxative that comes in a liquid form. 

Magnesium Citrate is a combination of the element magnesium and citric acid. 
Magnesium Citrate can be bought without a prescription in a drug store.

Magnesium Citrate may be used to treat occasional constipation and acid indigestion. 
Magnesium Citrate may also be prescribed to help clear the large intestine of stool before a test such as a colonoscopy or an operation on the digestive system.

Magnesium Citrate is used to treat occasional constipation.
Magnesium is a mineral that your body needs to function properly. 

There are many formulations of magnesium supplements available.
Magnesium Citrate is in a class of drugs called saline laxatives. 
Magnesium Citrate works by increasing fluid in the small intestine.  

Magnesium Citrate is a magnesium preparation in salt form with citric acid in a 1:1 ratio (1 magnesium atom per citrate molecule). 
The name "Magnesium Citrate" is ambiguous and sometimes may refer to other salts such as triMagnesium Citrate which has a magnesium:citrate ratio of 3:2.

Magnesium Citrate is used medicinally as a saline laxative and to completely empty the bowel prior to a major surgery or colonoscopy. 
Magnesium Citrate is available without a prescription, both as a generic and under various brand names. It is also used in the pill form as a magnesium dietary supplement. 

Magnesium Citrate contains 11.23% magnesium by weight. 
Compared to triMagnesium Citrate, it is much more water-soluble, less alkaline, and contains less magnesium.
As a food additive, Magnesium Citrate is used to regulate acidity and is known as E number E345.

Mechanism of Action:
Magnesium Citrate works by attracting water through the tissues by a process known as osmosis. 
Once in the intestine, it can attract enough water into the intestine to induce defecation. 

The additional water stimulates bowel motility. 
This means it can also be used to treat rectal and colon problems. 

Magnesium Citrate functions best on an empty stomach, and should always be followed with a full (eight ounce or 250 ml) glass of water or juice to help the Magnesium Citrate absorb properly and help prevent any complications. 
Magnesium Citrate solutions generally produce bowel movement in one half to three hours.

Magnesium Citrate (3:2) (3 magnesium atoms per 2 citrate molecules), also called trimagnesium bicitrate, trimagnesium dicitrate, triMagnesium Citrate, or the ambiguous name Magnesium Citrate. 
The substance Magnesium Citrate usually has water molecules attached to it. 

Magnesium Citrate is a (hydrated) salt of magnesium and citric acid. 
Magnesium Citrate is not very soluble in water and has a bitter taste

Magnesium is a naturally occurring element that is important to many systems in the body, especially muscles and nerves. 
Magnesium Citrate also increases intestinal water. 

Magnesium Citrate is used as a laxative for the treatment of occasional constipation. 
Magnesium Citrate is delivered as an oral tablet or as a liquid saline laxative. 
Magnesium Citrate retains water through osmosis in the intestines. 

Magnesium Citrate Uses:
This product is being used to clean stools from the intestines prior to surgery or certain intestinal procedures (e.g., colonoscopy, radiography), usually with other products. 
Magnesium Citrate may also be used to relieve constipation. 

However, milder products (e.g. stool softeners, bulk-forming laxatives) should be used for constipation whenever possible. 
Magnesium Citrate is a saline laxative which is thought to work by increasing the fluid in the small intestine. 
Magnesium Citrate usually results in intestinal movement within 30 minutes to 3 hours. 

The uses of Magnesium Citrate are:
*Bowel evacuation

*Constipation

*Bowel Irregularity

*Nutritional supplement and treats acid indigestion

Magnesium Citrate is supplied as an oral tablet or liquid saline laxative. 
Magnesium Citrate retains water in the intestines by osmosis. 
Increasing water in the bowel aids motility, usually producing a bowel movement within one-half to six hours.

Magnesium Citrate is the citrate salt of the element magnesium with cathartic activity. The cathartic action of magnesium cations appears to result, in part, from osmotically mediated water retention, which subsequently stimulates peristalsis. 
In addition, magnesium ions may also stimulate the activity of nitric oxide (NO) synthase and increase the biosynthesis of the phospholipid proinflammatory mediator platelet activating factor (PAF) in the gut. 

Magnesium Citrate is a low volume and osmotic cathartic agent. 
The cathartic action works primarily through the high osmolarity of the solution which draws large amounts of fluid into space where is used. 

Magnesium Citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg. 
Magnesium Citrate is also considered as an active ingredient in over-the-counter products.

Trimagnesium dicitrate is a magnesium salt composed of magnesium and citrate ions in a 3:2 ratio. 
Magnesium Citrate has a role as a laxative. 
Magnesium Citrate contains a citrate(3-).


PHYSICAL PROPERTIES:

-Molecular Weight: 451.12    

-Exact Mass: 449.9621801    

-Monoisotopic Mass: 449.9621801    

-Topological Polar Surface Area: 281 Ų    

-Melting Point: 184 ºC

-Solubility: Partially soluble in cold water


Magnesium Citrate is a commonly used agent that has an osmotic effect (as described earlier) and additionally stimulates the release of cholecystokinin, which results in intraluminal accumulation of fluid and electrolytes thought to promote colonic transit.
Magnesium Citrate is a low volume and osmotic cathartic agent. 

The cathartic action works primarily through the high osmolarity of the solution which draws large amounts of fluid into space where is used.
Magnesium Citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg.
Magnesium Citrate is also considered as an active ingredient in over-the-counter products.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 2    

-Hydrogen Bond Acceptor Count: 14    

-Rotatable Bond Count: 4    

-Heavy Atom Count: 29

-Formal Charge: 0

-Complexity: 211

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 5    

-Compound Is Canonicalized: Yes


Magnesium Citrate has been used in bowel preparations prior to a colonoscopy as a cathartic agent.
Magnesium Citrate is also used in over-the-counter products to relieve occasional constipation.

Magnesium Citrate can be one of the forms used for the administration of dietary supplements
Magnesium Citrate a magnesium salt composed of magnesium and dibasic citrate ions in a 1:1 ratio.

Magnesium Citrate is a magnesium preparation in salt form with citric acid in a 1:1 ratio (1 magnesium atom per citrate molecule). 
The name "Magnesium Citrate" is ambiguous and sometimes may refer to other salts such as triMagnesium Citrate which has a magnesium:citrate ratio of 3:2. 

Magnesium Citrate is used medicinally as a saline laxative and to completely empty the bowel prior to a major surgery or colonoscopy. 
Magnesium Citrate is available without a prescription, both as a generic and under various brand names. It is also used in the pill form as a magnesium dietary supplement. 

Magnesium Citrate contains 11.23% magnesium by weight. 
Compared to triMagnesium Citrate, it is much more water-soluble, less alkaline, and contains less magnesium. 
As a food additive, Magnesium Citrate is used to regulate acidity and is known as E number E345.

Magnesium is a mineral that supports us in the process of turning food into energy and helps us to produce hormones that aid healthy bones, and it’s found in foods like spinach, nuts, and wholemeal bread.
Magnesium Citrate, however, has a very specific purpose—as a natural relief for constipation.

Magnesium Citrate is a combination of magnesium, salt, and citric acid—also known as a “saline laxative” as it’s so effective in relieving constipation and helping to clear out the intestines
Magnesium Citrate comes in many different forms, making it easy to consume when and how you need to:
-Magnesium Citrate supplements

-Magnesium Citrate tablets

-Magnesium Citrate liquid

-Magnesium powder


Magnesium is a mineral that helps us to turn food into energy and supports healthy bones.
Magnesium Citrate is a combination of magnesium, salt, and citric acid.
The main use of Magnesium Citrate is to clear the bowels before certain procedures and as a natural form of constipation relief since it increases water in the intestines.

Magnesium is a naturally occurring mineral that is important for many systems in the body
Magnesium is a naturally occurring mineral that is important for many systems in the body, especially the muscles and nerves. 

Magnesium Citrate also increases water in the intestines.
Magnesium Citrate is used as a laxative to treat occasional constipation.

Magnesium is a naturally occurring mineral that is important for many systems in the body, especially the muscles and nerves. 
Magnesium Citrate also increases water in the intestines.

Magnesium Citrate is used as a laxative to treat occasional constipation.
Magnesium Citrate is also used to empty the colon (large intestine, bowel) before a colonoscopy (examination of the inside of the colon to check for colon cancer and other abnormalities) or certain medical procedures.

Magnesium Citrate can be used to help clean out your intestines before a colonoscopy
Magnesium Citrate is an osmotic laxative that comes in a liquid form. 

Magnesium Citrate is a combination of the element magnesium and citric acid. 
Magnesium Citrate can be bought without a prescription in a drug store.

Magnesium Citrate may be used to treat occasional constipation and acid indigestion. 
Magnesium Citrate may also be prescribed to help clear the large intestine of stool before a test such as a colonoscopy or an operation on the digestive system.

Magnesium Citrate is used to treat occasional constipation.
Magnesium is a mineral that your body needs to function properly. 

Magnesium Citrate is a (hydrated) salt of magnesium and citric acid. 
Magnesium Citrate is not very soluble in water and has a bitter taste

Magnesium is a naturally occurring element that is important to many systems in the body, especially muscles and nerves. 
Magnesium Citrate also increases intestinal water. 

Magnesium Citrate is used as a laxative for the treatment of occasional constipation. 
Magnesium Citrate is delivered as an oral tablet or as a liquid saline laxative. 
Magnesium Citrate retains water through osmosis in the intestines. 


SYNONYMS: 

Trimagnesium dicitrate
MAGNESIUM CITRATE
TriMagnesium Citrate
magnesium dicitrate
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, magnesium salt (2:3)
trimagnesium;2-hydroxypropane-1,2,3-tricarboxylate
Magnesium Citrate, Mg3(C6H5O7)2
Trimagnesiumdicitrat
MAGNESIUMCITRATE
Magnesium Citrate (VAN)
Magnesium Citrate [USP]
Magnesium Citrate (3:2)
Trimagnesiumdicitrate
EINECS 222-093-9
Tectlol (TN)
Tri Magnesium Citrate
EC 222-093-9
Magnesium Citrate
Citric acid, magnesium salt (2:3) (8CI)
magnesium 2-hydroxypropane-1,2,3-tricarboxylate (3/2)
1,2,3-Propanetricarboxylic acid, hydroxy-, magnesium salt (2:3)
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, magnesium salt (2:3) (9CI)
Citric acid, magnesium salt (2:3), 
Citric acid, magnesium salt (2:3) (8CI), 
EINECS 222-093-9 
LS-121081
MAGNESIUM CITRATE
Magnesium Citrate (3:2)
Magnesium Citrate
Mg3(C6H5O7)2
MAGNESIUM CITRATE
Magnesium Citrate (3:2)
Magnesium Citrate
Mg3(C6H5O7)2
Magnesium Citrate
NSC 83517
Trimagnesiumdicitrat
Trimagnesium dicitrate 

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