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MCT (MEDIUM CHAIN TRIGLYCERIDE)

MCT (Medium Chain Triglyceride) is a useful cosmetic agents as emollients, masking agent, perfuming agent, skin conditioning and solvents. 
As a fully saturated emollient tri-ester, MCT (Medium Chain Triglyceride) is recommended as an alternative for mineral or vegetable oils in a wide variety of personal care and pharmaceutical applicatxions. 
As a fully saturated triglyceride, MCT (Medium Chain Triglyceride) is light emollient with good lubricity.

CAS:    65381-09-1
MF:    C21H44O7
MW:    408.58
EINECS:    265-724-3

MCT (Medium Chain Triglyceride) is also an excellent solvent for chemical sunscreens and wetting agent for physical sunscreens.
MCT (Medium Chain Triglyceride) are fats that are made in a lab from coconut and palm kernel oils. 
Typical dietary fats are called long-chain triglycerides.

MCT (Medium Chain Triglyceride) are a fat source for people who cannot tolerate other types of fats. 
These fats might also improve weight loss because the body can more easily break them down into molecules called ketone bodies. 
These ketone bodies can be used for energy.
MCT (Medium Chain Triglyceride) are triglycerides with two or three fatty acids having an aliphatic tail of 6–12 carbon atoms, i.e. medium-chain fatty acids (MCFAs). 
Rich food sources for commercial extraction of MCT (Medium Chain Triglyceride) include palm kernel oil and coconut oil.
MCT (Medium Chain Triglyceride) are found in palm kernel oil and coconut oil and can be separated by fractionation.
They can also be produced by interesterification.
Retail MCT (Medium Chain Triglyceride) powder is MCT oil embedded in starch and thus contains carbohydrates in addition to fats. 
MCT (Medium Chain Triglyceride) is manufactured by spray drying.

MCT (Medium Chain Triglyceride) are types of fat, and they have been shown to have benefits to health and performance. 
MCT (Medium Chain Triglyceride) are the main constituents of fats and each triglyceride is made up of three fatty acids with a backbone of glycerol. 
The majority of fats found in our food are long-chain triglycerides (LCTs). 
MCT (Medium Chain Triglyceride) are triglycerides where the fatty acids in their structure are 6 to 12 carbon atoms in length.

MCT (Medium Chain Triglyceride) is a liquid glycol ether with chemical stability. 
MCT (Medium Chain Triglyceride) is used in the formulation of pharmaceutical preparations, cosmetic products, and dietary supplements. 
MCT (Medium Chain Triglyceride) is used as a solvent for serine proteases and copper complexes in the clinical setting.

Uses
MCT (Medium Chain Triglyceride) is widely used in sunscreen oil, cream and lotion; after-sun protection cream and lotion; used in hair modification oil, cream and head oil, which can make the hair shiny, smooth and easy to comb; bath oil; skin care oil and nutrient solution. 
MCT (Medium Chain Triglyceride) makes the skin lubricated and shiny, and the nutrition is easily absorbed by the skin, which plays a very good role in the uniform and delicate cosmetics.

Calorie Restriction
A 2020 systematic review and meta-analysis supported evidence that MCT (Medium Chain Triglyceride) decreases subsequent energy intake, but does not appear to affect appetite.

Dietary Relevance
Molecular weight analysis of milk from different species showed that while milk fats from all studied species were primarily composed of long-chain fatty acids (16 and 18 carbons long), approximately 10–20% of the fatty acids in milk from horses, cows, sheep, and goats were medium-chain fatty acids.

Some studies have shown that MCT (Medium Chain Triglyceride) can help in the process of excess calorie burning, thus weight loss.
MCT (Medium Chain Triglyceride) are also seen as promoting fat oxidation and reduced food intake.
MCT (Medium Chain Triglyceride) have been recommended by some endurance athletes and the bodybuilding community.
While health benefits from MCT (Medium Chain Triglyceride) seem to occur, a link to improved exercise performance is inconclusive.
A number of studies back the use of MCT (Medium Chain Triglyceride) as a weight loss supplement, but these claims are not without conflict, as about an equal number found inconclusive results.

Pharma Relevance
MCT (Medium Chain Triglyceride) can be used in solutions, liquid suspensions and lipid-based drug delivery systems for emulsions, self-emulsifying drug delivery systems, creams, ointments, gels and foams as well as suppositories. 
MCT (Medium Chain Triglyceride) are also suitable for use as solvent and liquid oily lubricant in soft gels. 
Brand names of pharma-grade MCT (Medium Chain Triglyceride) include Kollisolv MCT 70.

Medical Relevance
MCT (Medium Chain Triglyceride) passively diffuse from the GI tract to the portal system (longer fatty acids are absorbed into the lymphatic system) without requirement for modification like long-chain fatty acids or very-long-chain fatty acids. 
In addition, MCT (Medium Chain Triglyceride) do not require bile salts for digestion. 
Patients who have malnutrition, malabsorption or particular fatty-acid metabolism disorders are treated with MCT (Medium Chain Triglyceride) because MCTs do not require energy for absorption, use, or storage.

MCT (Medium Chain Triglyceride) are generally considered a good biologically inert source of energy that the human body finds reasonably easy to metabolize. 
They have potentially beneficial attributes in protein metabolism, but may be contraindicated in some situations due to a reported tendency to induce ketogenesis and metabolic acidosis.
However, there is other evidence demonstrating no risk of ketoacidosis or ketonemia with MCT (Medium Chain Triglyceride) at levels associated with normal consumption, and that the moderately elevated blood ketones can be an effective treatment for epilepsy.

Due to their ability to be absorbed rapidly by the body, MCT (Medium Chain Triglyceride) have found use in the treatment of a variety of malabsorption ailments. 
MCT (Medium Chain Triglyceride) supplementation with a low-fat diet has been described as the cornerstone of treatment for Waldmann disease.
MCT (Medium Chain Triglyceride) are an ingredient in some specialised parenteral nutritional emulsions in some countries.
Studies have also shown promising results for epilepsy through the use of ketogenic dieting.

Technical uses
MCT (Medium Chain Triglyceride) are bland compared to other fats and do not generate off-notes (dissonant tastes) as quickly as LCTs. 
They are also more polar than LCTs. 
Because of these attributes, they are widely used as carrier oils or solvents for flavours and oral medicines and vitamins.

Synonyms
Caprylic/Capric Triglyceride, CoMMiphora Mukul Resin Extract
2-hydroxy-3-(octanoyloxy)propyldecanoate
1-hydroxy-3-(octanoyloxy)propan-2-yl decanoate
Triglyceride、Hydrogenated Retinol
Medium-Chain Triglycerides (MCT)
Decanoic acid ester with 1,2,3-propanetriol octanoate
decanoyl/octanoyl-glycerides
Octanoic/decanoic triglyceride

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